L5 is a small haplogroup centered in East Africa. The highest frequency is in MbutiPygmies from Eastern Central Africa at 15%.[3] It is present in relatively small frequencies in Tanzania (Sandawe and others), Kenya, Chad, Ethiopia, Sudan, Nubia, Egypt[4][Note 1] and Saudi Arabia.[5]
Haplogroup L5 has been observed among specimens at the island cemetery in Kulubnarti, Sudan, which date from the Early Christian period (AD 550–800).[6]
Subcladesedit
Treeedit
This phylogenetic tree of haplogroup L5 subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[2] and subsequent published research.
Most Recent Common Ancestor (MRCA)
L1-6
L2-6
L5
L5a
L5a1
L5a1a
L5a1b
L5a1c
L5a2
L5c
L5c1
L5c2
Referencesedit
^Soares, P; Ermini, L; Thomson, N; Mormina, M; Rito, T; Röhl, A; Salas, A; Oppenheimer, S; MacAulay, V (2009). "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock". American Journal of Human Genetics. 84 (6): 740–59. doi:10.1016/j.ajhg.2009.05.001. PMC2694979. PMID 19500773.
^ abvan Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457. S2CID 27566749.
^Sarah A. Tishkoff et al. 2007, Molecular Biology and Evolution 2007 24(10):2180-2195
^Stevanovitch, A; A. Gilles; E. Bouzaid; R. Kefi; F. Paris; R. P. Gayraud; J. L. Spadoni; F. El-Chenawi; E. Béraud-Colomb (29 Jan 2004). "Mitochondrial DNA Sequence Diversity in a Sedentary Population from Egypt". Annals of Human Genetics. 68 (1): 23–39. doi:10.1046/j.1529-8817.2003.00057.x. PMID 14748828. S2CID 44901197.
^Abu-Amero et al. 2008 February. "Mitochondrial DNA structure in the Arabian Peninsula", BMC Evolutionary Biology. 8(45): 52.
^Sirak, Kendra; Frenandes, Daniel; Novak, Mario; Van Gerven, Dennis; Pinhasi, Ron (2016). "Abstract Book of the IUAES Inter-Congress 2016 - A community divided? Revealing the community genome(s) of Medieval Kulubnarti using next- generation sequencing". Abstract Book of the Iuaes Inter-Congress 2016. IUAES: 115.
haplogroup, human, mitochondrial, mtdna, clade, previously, known, possible, time, origin114, possible, place, origineast, africa, upper, nile, valleyancestorl2, 6descendantsl5a, l5cdefining, mutations3423, 7972, 12432, 12950, contents, distribution, subclades. Haplogroup L5 is a human mitochondrial DNA mtDNA clade It was previously known as L1e Haplogroup L5Possible time of origin114 200 126 200 YBP 1 Possible place of originEast Africa Upper Nile ValleyAncestorL2 6DescendantsL5a L5cDefining mutations3423 7972 12432 12950 2 Contents 1 Distribution 2 Subclades 2 1 Tree 3 References 4 Notes 5 External linksDistribution editL5 is a small haplogroup centered in East Africa The highest frequency is in Mbuti Pygmies from Eastern Central Africa at 15 3 It is present in relatively small frequencies in Tanzania Sandawe and others Kenya Chad Ethiopia Sudan Nubia Egypt 4 Note 1 and Saudi Arabia 5 Haplogroup L5 has been observed among specimens at the island cemetery in Kulubnarti Sudan which date from the Early Christian period AD 550 800 6 Subclades editTree edit This phylogenetic tree of haplogroup L5 subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation 2 and subsequent published research Most Recent Common Ancestor MRCA L1 6 L2 6 L5 L5a L5a1 L5a1a L5a1b L5a1c L5a2 L5c L5c1 L5c2References edit Soares P Ermini L Thomson N Mormina M Rito T Rohl A Salas A Oppenheimer S MacAulay V 2009 Correcting for Purifying Selection An Improved Human Mitochondrial Molecular Clock American Journal of Human Genetics 84 6 740 59 doi 10 1016 j ajhg 2009 05 001 PMC 2694979 PMID 19500773 a b van Oven Mannis Manfred Kayser 13 Oct 2008 Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation Human Mutation 30 2 E386 E394 doi 10 1002 humu 20921 PMID 18853457 S2CID 27566749 Sarah A Tishkoff et al 2007 History of Click Speaking Populations of Africa Inferred from mtDNA and Y Chromosome Genetic Variation Molecular Biology and Evolution 2007 24 10 2180 2195 Stevanovitch A A Gilles E Bouzaid R Kefi F Paris R P Gayraud J L Spadoni F El Chenawi E Beraud Colomb 29 Jan 2004 Mitochondrial DNA Sequence Diversity in a Sedentary Population from Egypt Annals of Human Genetics 68 1 23 39 doi 10 1046 j 1529 8817 2003 00057 x PMID 14748828 S2CID 44901197 Abu Amero et al 2008 February Mitochondrial DNA structure in the Arabian Peninsula BMC Evolutionary Biology 8 45 52 Sirak Kendra Frenandes Daniel Novak Mario Van Gerven Dennis Pinhasi Ron 2016 Abstract Book of the IUAES Inter Congress 2016 A community divided Revealing the community genome s of Medieval Kulubnarti using next generation sequencing Abstract Book of the Iuaes Inter Congress 2016 IUAES 115 Notes edit Sample UPE52 is subclade L5a External links edit nbsp Wikimedia Commons has media related to Haplogroup L5 mtDNA General Mannis van Oven s Phylotree Haplogroup L5 Ian Logan s Haplogroup L5 YFull MTree s Haplogroup L5 MITOMAP s Haplogroup L5 Phylogenetic tree of human mitochondrial DNA mtDNA haplogroups Mitochondrial Eve L L0 L1 6 L1 L2 L3 L4 L5 L6M N CZ D E G Q O A S R I W X YC Z B F R0 pre JT P UHV JT KH V J T nbsp This genetics article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Haplogroup L5 amp oldid 1197522808, wikipedia, wiki, book, books, library,
