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Life expectancy

Life expectancy is a statistical measure of the average time an organism is expected to live, based on the year of its birth, current age, and other demographic factors like sex. The most commonly used measure is life expectancy at birth (LEB), which can be defined in two ways. Cohort LEB is the mean length of life of a birth cohort (all individuals born in a given year) and can be computed only for cohorts born so long ago that all their members have died. Period LEB is the mean length of life of a hypothetical cohort[1][2] assumed to be exposed, from birth through death, to the mortality rates observed at a given year.[3]

Life expectancy in USA, China and Russia, 1960–2020
Life expectancy in the largest European countries, 1960–2020
Life expectancy at birth, measured by region, between 1950 and 2050
Life expectancy by world region, from 1770 to 2018
Gender Die Gap: global gender life expectancy gap at birth for countries and territories as defined by WHO for 2019. Open the original svg-file and hover over a bubble to show its data. The square of the bubbles is proportional to country population based on estimation of the UN.

National LEB figures reported by national agencies and international organizations for human populations are estimates of period LEB. In the Bronze Age and the Iron Age, human LEB was 26 years; in 2010, world LEB was 67.2 years. In recent years, LEB in Eswatini (formerly Swaziland) is 49, while LEB in Japan is 83. The combination of high infant mortality and deaths in young adulthood from accidents, epidemics, plagues, wars, and childbirth, before modern medicine was widely available, significantly lowers LEB. For example, a society with a LEB of 40 would have relatively few people dying at exactly 40: most will die before 30 or after 55. In populations with high infant mortality rates, LEB is highly sensitive to the rate of death in the first few years of life. Because of this sensitivity, LEB can be grossly misinterpreted, leading to the belief that a population with a low LEB would have a small proportion of older people.[4] A different measure, such as life expectancy at age 5 (e5), can be used to exclude the effect of infant mortality to provide a simple measure of overall mortality rates other than in early childhood. For instance, in a society with a life expectancy of 30, it may nevertheless be common to have a 40-year remaining timespan at age 5 (but perhaps not a 60-year one).

Until the middle of the 20th century, infant mortality was approximately 40–60% of the total mortality. Excluding child mortality, the average life expectancy during the 12th–19th centuries was approximately 55 years. If a person survived childhood, they had about a 50% chance of living 50–55 years, instead of only 25–40 years.[5]

Aggregate population measures—such as the proportion of the population in various age groups—are also used alongside individual-based measures—such as formal life expectancy—when analyzing population structure and dynamics. Pre-modern societies had universally higher mortality rates and lower life expectancies at every age for both males and females. This example is relatively rare.

Life expectancy, longevity, and maximum lifespan are not synonymous. Longevity refers to the relatively long lifespan of some members of a population. Maximum lifespan is the age at death for the longest-lived individual of a species. Mathematically, life expectancy is denoted [a] and is the mean number of years of life remaining at a given age , with a particular mortality.[6] Because life expectancy is an average, a particular person may die many years before or after the expected survival.

Life expectancy is also used in plant or animal ecology,[7] and in life tables (also known as actuarial tables). The concept of life expectancy may also be used in the context of manufactured objects,[8] though the related term[dubious ] shelf life is commonly used for consumer products, and the terms "mean time to breakdown" (MTTB) and "mean time between failures" (MTBF) are used in engineering.

Human patterns

Maximum

The longest verified lifespan for any human is that of Frenchwoman Jeanne Calment, who is verified as having lived to age 122 years, 164 days, between 21 February 1875 and 4 August 1997. This is referred to as the "maximum life span," which is the upper boundary of life, the maximum number of years any human is known to have lived.[9] A theoretical study shows that the maximum life expectancy at birth is limited by the human life characteristic value δ, which is around 104 years.[10] According to a study by biologists Bryan G. Hughes and Siegfried Hekimi, there is no evidence for limit on human lifespan.[11][12] However, this view has been questioned on the basis of error patterns.[13]

Records of human lifespan above age 100 are highly susceptible to errors.[13] For example, the previous world-record holder for human lifespan, Carrie C. White was uncovered as a simple typographic error after more than two decades.[13][failed verification]

Variation over time

The following information is derived from the 1961 Encyclopædia Britannica and other sources, some with questionable accuracy. Unless otherwise stated, it represents estimates of the life expectancies of the world population as a whole. In many instances, life expectancy varied considerably according to class and gender.

Life expectancy at birth takes account of infant mortality and child mortality but not prenatal mortality.

Era Life expectancy at birth in years Notes
Paleolithic 22–33[14] Based on the data from modern hunter-gatherer populations, it is estimated that at 15, life expectancy was an additional 39 years (total 54), with a 60% probability of reaching 15.[15]
Neolithic 20[16] – 33[17] Based on Early Neolithic data, total life expectancy at 15 would be 28–33 years.[18]
Bronze Age and Iron Age[19] 26 Based on Early and Middle Bronze Age data, total life expectancy at 15 would be 28–36 years.[18]
Classical Greece[20] 25[21] – 28[22] Based on Athens Agora and Corinth data, total life expectancy at 15 would be 37–41 years.[18] Most Greeks and Romans died young. About half of all children died before adolescence. Those who survived to the age of 30 had a reasonable chance of reaching 50 or 60. The truly elderly, however, were rare. Because so many died in childhood, life expectancy at birth was probably between 20 and 30 years.[23]
Classical Rome 20–33

[24][25][26][23][14][27]

Data is lacking, but computer models provide the estimate. If a person survived to age 20, they could expect to live around 30 years more. Life expectancy was probably slightly longer for women than men.[28]

When infant mortality is factored out (i.e. counting only the 67[24]–75% who survived the first year), life expectancy is around 34–41 more years (i.e. expected to live to 35–42). When child mortality is factored out (i.e. counting only the 55-65% who survived to age 5), life expectancy is around 40–45 (i.e. age 45–50).[26] The ~50% that reached age 10 could also expect to reach ~45-50;[24] at 15 to ~48–54; at 40 to ~60;[24] at 50 to ~64–68; at 60 to ~70–72; at 70 to ~76–77.[26][28]

Vedic India 50 50-75 was considered the average lifespan by Vedic texts.[29] Ancient Ayurveda focused on cleaning body, boiling water before drinking and similar modern sanitisation practices.
Wang clan of China, 1st c. AD – 1749 35 For the 60% that survived the first year (i.e. excluding infant mortalities), life expectancy rose to ~35.[30][31]
Early Middle Ages (Europe, from the late 5th or early 6th century to the 10th century) 30–35 Life expectancy for those of both sexes who survived birth averaged about 30–35 years. However, if a Gaulish boy made it past age 20, he might expect to live 25 more years, while a woman at age 20 could normally expect about 17 more years. Anyone who survived until 40 had a good chance at another 15 to 20 years.[32]
Pre-Columbian Mesoamerica[33] >40 The average Aztec life expectancy was 41.2 years for men and 42.1 for women.
Late medieval English peerage[34][35] 30–33[27] In Europe, around one-third of infants died in their first year.[14] Once children reached the age of 10, their life expectancy was 32.2 years, and for those who survived to 25, the remaining life expectancy was 23.3 years. Such estimates reflected the life expectancy of adult males from the higher ranks of English society in the Middle Ages, and were similar to that computed for monks of the Christ Church in Canterbury during the 15th century.[27] At age 21, life expectancy of an aristocrat was an additional 43 years (total age 64).[36]
Early modern England (16th – 18th century)[19] 33–40 For males in the 18th century it was 34 years.[37] For 15-year-old girls: around the 15th – 16th century it was ~33 years (48 total), and in the 18th century it was ~42 (57 total).[38]
18th-century England[39][14] 25–40 For most of the century it ranged from 35 to 40; however, in the 1720s it dipped as low as 25.[39] For 15-year-old girls, it was ~42 (57 total).[38] During the second half of the century it was ~37,[40] while for the elite it passed 40 and approached 50.[30]
Pre-Champlain Canadian Maritimes[41] 60 Samuel de Champlain wrote that in his visits to Mi'kmaq and Huron communities, he met people over 100 years old. Daniel Paul attributes the incredible lifespan in the region to low stress and a healthy diet of lean meats, diverse vegetables, and legumes.[42]
18th-century Prussia[37] 24.7 For males.[37]
18th-century France[37] 27.5–30 For males:[37] 24.8 years in 1740–1749, 27.9 years in 1750–1759, 33.9 years in 1800–1809.[31]
18th-century American colonies[14] 28 Massachusetts colonists who reached the age of 50 could expect to live until 71, and those who were still alive at 60 could expect to reach 75.
Beginning of the 19th century[39] ~29 Demographic research suggests that at the beginning of the 19th century, no country in the world had a life expectancy longer than 40 years. India was ~25 years, while Belgium was ~40 years.[39] For Europe as a whole, it was ~33 years.[40]
Early 19th-century England[19][39][30] 40 For the 84% who survived the first year (i.e. excluding infant mortality), the average age was ~46[30]–48. If they reached 20, then it was ~60; if 50, then ~70; if 70, then ~80.[39] For a 15-year-old girl it was ~60–65.[38] For the upper-class, LEB rose from ~45 to 50.[30]

Less than half of the people born in the mid-19th century made it past their 50th birthday. In contrast, 97% of the people born in 21st century England and Wales can expect to live longer than 50 years.[39]

19th-century British India[43] 25.4
19th-century world average[39] 28.5–32 Over the course of the century: Europe rose from ~33 to 43, the Americas from ~35 to 41, Oceania ~35 to 48, Asia ~28, Africa 26.[39] In 1820s France, LEB was ~38, and for the 80% that survived, it rose to ~47. For Moscow serfs, LEB was ~34, and for the 66% that survived, it rose to ~36.[30] Western Europe in 1830 was ~33 years, while for the people of Hau-Lou in China, it was ~40.[40] The LEB for a 10-year-old in Sweden rose from ~44 to ~54.[39]
1900 world average[44] 31–32[39] Around 48 years in Oceania, 43 in Europe, and 41 in the Americas.[39] Around 47 in the U.S.[14] and around 48 for 15-year-old girls in England.[38]
1950 world average[44] 45.7–48[39] Around 60 years in Europe, North America, Oceania, Japan, and parts of South America; but only 41 in Asia and 36 in Africa. Norway led with 72, while in Mali it was merely 26.[39]
2019–2020 world average 72.6–73.2
[39][45][46]
  • Females: 75.6 years
  • Males: 70.8 years
  • Range: ~54 (Central African Republic) – 85.3 (Hong Kong)[46]

Life expectancy increases with age as the individual survives the higher mortality rates associated with childhood. For instance, the table above gives the life expectancy at birth among 13th-century English nobles at 30. Having survived to the age of 21, a male member of the English aristocracy in this period could expect to live:[36]

  • 1200–1300: to age 64
  • 1300–1400: to age 45 (because of the bubonic plague)
  • 1400–1500: to age 69
  • 1500–1550: to age 71

17th-century English life expectancy was only about 35 years, largely because infant and child mortality remained high. Life expectancy was under 25 years in the early Colony of Virginia,[47] and in seventeenth-century New England, about 40% died before reaching adulthood.[48] During the Industrial Revolution, the life expectancy of children increased dramatically.[49] The under-5 mortality rate in London decreased from 74.5% (in 1730–1749) to 31.8% (in 1810–1829).[50][51]

Public health measures are credited with much of the recent increase in life expectancy. During the 20th century, despite a brief drop due to the 1918 flu pandemic,[52] the average lifespan in the United States increased by more than 30 years, of which 25 years can be attributed to advances in public health.[53]

Regional variations

 
Life expectancy in 1800, 1950, and 2015 – visualization by Our World in Data

Human beings are expected to live on average 30–40 years in Eswatini[54] and 82.6 years in Japan.[b] An analysis published in 2011 in The Lancet attributes Japanese life expectancy to equal opportunities, public health, and diet.[56][57]

 
Plot of life expectancy vs. GDP per capita in 2009. This phenomenon is known as the Preston curve.
 
Graphs of life expectancy at birth for some sub-Saharan countries showing the fall in the 1990s primarily due to the HIV pandemic[58]

There are great variations in life expectancy between different parts of the world, mostly caused by differences in public health, medical care, and diet. The impact of AIDS on life expectancy is particularly notable in many African countries. According to projections made by the United Nations in 2002, the life expectancy at birth for 2010–2015 (if HIV/AIDS did not exist) would have been:[59]

  • 70.7 years instead of 31.6 years, Botswana
  • 69.9 years instead of 41.5 years, South Africa
  • 70.5 years instead of 31.8 years, Zimbabwe

Actual life expectancy in Botswana declined from 65 in 1990 to 49 in 2000 before increasing to 66 in 2011. In South Africa, life expectancy was 63 in 1990, 57 in 2000, and 58 in 2011. And in Zimbabwe, life expectancy was 60 in 1990, 43 in 2000, and 54 in 2011.[60]

During the last 200 years, African countries have generally not had the same improvements in mortality rates that have been enjoyed by countries in Asia, Latin America, and Europe.[61][62]

In the United States, African-American people have shorter life expectancies than their European-American counterparts. For example, white Americans in 2010 are expected to live until age 78.9, but black Americans only until age 75.1. This 3.8-year gap, however, is the lowest it has been since 1975 at the latest. The greatest difference was 7.1 years in 1993.[63] In contrast, Asian-American women live the longest of all ethnic groups in the United States, with a life expectancy of 85.8 years.[64] The life expectancy of Hispanic-Americans is 81.2 years.[63] According to the new government reports in the US, life expectancy in the country dropped again because of the rise in suicide and drug overdose rates. The Centers for Disease Control (CDC) found nearly 70,000 more Americans died in 2017 than in 2016, with rising rates of death among 25- to 44-year-olds.[65]

Cities also experience a wide range of life expectancy based on neighborhood breakdowns. This is largely due to economic clustering and poverty conditions that tend to associate based on geographic location. Multi-generational poverty found in struggling neighborhoods also contributes. In United States cities such as Cincinnati, the life expectancy gap between low income and high-income neighborhoods touches 20 years.[66]

Economic circumstances

 
Life expectancy is higher in rich countries with low economic inequality.[67]
 
Life expectancy vs healthcare spending of rich OECD countries[68]

Economic circumstances also affect life expectancy. For example, in the United Kingdom, life expectancy in the wealthiest and richest areas is several years higher than in the poorest areas. This may reflect factors such as diet and lifestyle, as well as access to medical care. It may also reflect a selective effect: people with chronic life-threatening illnesses are less likely to become wealthy or to reside in affluent areas.[69] In Glasgow, the disparity is amongst the highest in the world: life expectancy for males in the heavily deprived Calton area stands at 54, which is 28 years less than in the affluent area of Lenzie, which is only 8 km (5.0 mi) away.[70][71]

A 2013 study found a pronounced relationship between economic inequality and life expectancy.[72] However, in contrast, a study by José A. Tapia Granados and Ana Diez Roux at the University of Michigan found that life expectancy actually increased during the Great Depression, and during recessions and depressions in general.[73] The authors suggest that when people are working at a more extreme degree during prosperous economic times, they undergo more stress, exposure to pollution, and the likelihood of injury among other longevity-limiting factors.

Life expectancy is also likely to be affected by exposure to high levels of highway air pollution or industrial air pollution. This is one way that occupation can have a major effect on life expectancy. Coal miners (and in prior generations, asbestos cutters) often have lower life expectancies than average. Other factors affecting an individual's life expectancy are genetic disorders, drug use, tobacco smoking, excessive alcohol consumption, obesity, access to health care, diet, and exercise.

Sex differences

 
Pink: Countries where female life expectancy at birth is higher than males. Blue: A few countries in southern Africa where females have shorter lives due to AIDS.[74]

In the present, female human life expectancy is greater than that of males, despite females having higher morbidity rates (see Health Survival paradox). There are many potential reasons for this. Traditional arguments tend to favor sociology-environmental factors: historically, men have generally consumed more tobacco, alcohol, and drugs than women in most societies, and are more likely to die from many associated diseases such as lung cancer, tuberculosis, and cirrhosis of the liver.[75] Men are also more likely to die from injuries, whether unintentional (such as occupational, war, or car accidents) or intentional (suicide).[75] Men are also more likely to die from most of the leading causes of death (some already stated above) than women. Some of these in the United States include cancer of the respiratory system, motor vehicle accidents, suicide, cirrhosis of the liver, emphysema, prostate cancer, and coronary heart disease.[9] These far outweigh the female mortality rate from breast cancer and cervical cancer. In the past, mortality rates for females in child-bearing age groups were higher than for males at the same age.

A paper from 2015 found that female fetuses have a higher mortality rate than male fetuses.[76] This finding contradicts papers dating from 2002 and earlier that attribute the male sex to higher in-utero mortality rates.[77][78][79] Among the smallest premature babies (those under 2 pounds (910 grams)), females have a higher survival rate. At the other extreme, about 90% of individuals aged 110 are female. The difference in life expectancy between men and women in the United States dropped from 7.8 years in 1979 to 5.3 years in 2005, with women expected to live to age 80.1 in 2005.[80] Data from the United Kingdom shows the gap in life expectancy between men and women decreasing in later life. This may be attributable to the effects of infant mortality and young adult death rates.[81]

Some argue that shorter male life expectancy is merely another manifestation of the general rule, seen in all mammal species, that larger-sized individuals within a species tend, on average, to have shorter lives.[82][83] This biological difference[clarification needed] occurs because women have more resistance to infections and degenerative diseases.[9]

In her extensive review of the existing literature, Kalben concluded that the fact that women live longer than men was observed at least as far back as 1750 and that, with relatively equal treatment, today males in all parts of the world experience greater mortality than females. However, Kalben's study was restricted to data in Western Europe alone, where the demographic transition occurred relatively early. United Nations statistics from mid-twentieth century onward, show that in all parts of the world, females have a higher life expectancy at age 60 than males.[84] Of 72 selected causes of death, only 6 yielded greater female than male age-adjusted death rates in 1998 in the United States. Except for birds, for almost all of the animal species studied, males have higher mortality than females. Evidence suggests that the sex mortality differential in people is due to both biological/genetic and environmental/behavioral risk and protective factors.[85]

One recent suggestion is that mitochondrial mutations which shorten lifespan continue to be expressed in males (but less so in females) because mitochondria are inherited only through the mother. By contrast, natural selection weeds out mitochondria that reduce female survival; therefore, such mitochondria are less likely to be passed on to the next generation. This thus suggests that females tend to live longer than males. The authors claim that this is a partial explanation.[86][87]

Another explanation is the unguarded X hypothesis. According to this hypothesis, one reason for why the average lifespan of males isn't as long as that of females––by 18% on average, according to the study––is that they have a Y chromosome which can't protect an individual from harmful genes expressed on the X chromosome, while a duplicate X chromosome, as present in female organisms, can ensure harmful genes aren't expressed.[88][89]

Before the Industrial Revolution, men lived longer than women on average.[90][91] In developed countries, starting around 1880, death rates decreased faster among women, leading to differences in mortality rates between males and females. Before 1880, death rates were the same. In people born after 1900, the death rate of 50- to 70-year-old men was double that of women of the same age. Men may be more vulnerable to cardiovascular disease than women, but this susceptibility was evident only after deaths from other causes, such as infections, started to decline.[92] Most of the difference in life expectancy between the sexes is accounted for by differences in the rate of death by cardiovascular diseases among persons aged 50–70.[93]

Genetics

The heritability of lifespan is estimated to be less than 10%, meaning the majority of variation in lifespan is attributable due to differences in environment rather than genetic variation.[94] However, researchers have identified regions of the genome which can influence the length of life and the number of years lived in good health. For example, a genome-wide association study of 1 million lifespans found 12 genetic loci which influenced lifespan by modifying susceptibility to cardiovascular and smoking-related disease.[95] The locus with the largest effect is APOE. Carriers of the APOE ε4 allele live approximately one year less than average (per copy of the ε4 allele), mainly due to increased risk of Alzheimer's disease.[95]

 
"Healthspan, parental lifespan, and longevity are highly genetically correlated."[96]

In July 2020, scientists identified 10 genomic loci with consistent effects across multiple lifespan-related traits, including healthspan, lifespan, and longevity.[96] The genes affected by variation in these loci highlighted haem metabolism as a promising candidate for further research within the field. This study suggests that high levels of iron in the blood likely reduce, and genes involved in metabolising iron likely increase healthy years of life in humans.[97]

A follow-up study which investigated the genetics of frailty and self-rated health in addition to healthspan, lifespan, and longevity also highlighted haem metabolism as an important pathway, and found genetic variants which lower blood protein levels of LPA and VCAM1 were associated with increased healthy lifespan.[98]

Centenarians

In developed countries, the number of centenarians is increasing at approximately 5.5% per year, which means doubling the centenarian population every 13 years, pushing it from some 455,000 in 2009 to 4.1 million in 2050.[99] Japan is the country with the highest ratio of centenarians (347 for every 1 million inhabitants in September 2010). Shimane Prefecture had an estimated 743 centenarians per million inhabitants.[100]

In the United States, the number of centenarians grew from 32,194 in 1980 to 71,944 in November 2010 (232 centenarians per million inhabitants).[101]

Mental illness

Mental illness is reported to occur in approximately 18% of the average American population.[102][103]

 
Life expectancy in the seriously mentally ill is much shorter than the general population.[104]

The mentally ill have been shown to have a 10- to 25-year reduction in life expectancy.[105] Generally, the reduction of lifespan in the mentally ill population compared to the mentally stable population has been studied and documented.[106][107][108][109][110]

The greater mortality of people with mental disorders may be due to death from injury, from co-morbid conditions, or medication side effects.[111] For instance, psychiatric medications can increase the risk of developing diabetes.[112][113][114][115] It has been shown that the psychiatric medication olanzapine can increase risk of developing agranulocytosis, among other comorbidities.[116][117] Psychiatric medicines also affect the gastrointestinal tract; the mentally ill have a four times risk of gastrointestinal disease.[118][119][120]

As of 2020 and the COVID-19 pandemic, researchers have found an increased risk of death in the mentally ill.[121][122][123]

Other illnesses

The life expectancy of people with diabetes, which is 9.3% of the U.S. population, is reduced by roughly 10–20 years.[124][125] People over 60 years old with Alzheimer's disease have about a 50% life expectancy of 3–10 years.[126] Other demographics that tend to have a lower life expectancy than average include transplant recipients[127] and the obese.[128]

Education

Education on all levels has been shown to be strongly associated with increased life expectancy.[129] This association may be due partly to higher income,[130] which can lead to increased life expectancy. Despite the association, among identical twin pairs with different education levels, there is only weak evidence of a relationship between educational attainment and adult mortality.[129]

According to a paper from 2015, the mortality rate for the Caucasian population in the United States from 1993 to 2001 is four times higher[dubious ] for those who did not complete high school compared to those who have at least 16 years of education.[129] In fact, within the U.S. adult population, people with less than a high school education have the shortest life expectancies.

Preschool education also plays a large role in life expectancy. It was found that high-quality early-stage childhood education had positive effects on health. Researchers discovered this by analyzing the results of the Carolina Abecedarian Project, finding that the disadvantaged children who were randomly assigned to treatment had lower instances of risk factors for cardiovascular and metabolic diseases in their mid-30s.[131]

Evolution and aging rate

Various species of plants and animals, including humans, have different lifespans. Evolutionary theory states that organisms which—by virtue of their defenses or lifestyle—live for long periods and avoid accidents, disease, predation, etc. are likely to have genes that code for slow aging, which often translates to good cellular repair. One theory is that if predation or accidental deaths prevent most individuals from living to an old age, there will be less natural selection to increase the intrinsic life span.[132] That finding was supported in a classic study of opossums by Austad;[133] however, the opposite relationship was found in an equally prominent study of guppies by Reznick.[134][135]

One prominent and very popular theory states that lifespan can be lengthened by a tight budget for food energy called caloric restriction.[136] Caloric restriction observed in many animals (most notably mice and rats) shows a near doubling of life span from a very limited calorific intake. Support for the theory has been bolstered by several new studies linking lower basal metabolic rate to increased life expectancy.[137][138][139] That is the key to why animals like giant tortoises can live so long.[140] Studies of humans with life spans of at least 100 have shown a link to decreased thyroid activity, resulting in their lowered metabolic rate.[citation needed]

In a broad survey of zoo animals, no relationship was found between investment of the animal in reproduction and its life span.[141]

Calculation

 
A survival tree to explain the calculations of life-expectancy. Red numbers indicate a chance of survival at a specific age, and blue ones indicate age-specific death rates.

In actuarial notation, the probability of surviving from age   to age   is denoted   and the probability of dying during age   (i.e. between ages   and  ) is denoted   . For example, if 10% of a group of people alive at their 90th birthday die before their 91st birthday, the age-specific death probability at 90 would be 10%. This probability describes the likelihood of dying at that age, and is not the rate at which people of that age die.[c] It can be shown that

 

 

 

 

 

(1)

The curtate future lifetime, denoted  , is a discrete random variable representing the remaining lifetime at age  , rounded down to whole years. Life expectancy, more technically called the curtate expected lifetime and denoted   ,[a] is the mean of  —that is to say, the expected number of whole years of life remaining, assuming survival to age  .[142] So,

 

 

 

 

 

(2)

Substituting (1) into the sum and simplifying gives the final result [143]

 

 

 

 

 

(3)

If the assumption is made that, on average, people live a half year on the year of their death, the complete life expectancy at age   would be  .

By definition, life expectancy is an arithmetic mean. It can also be calculated by integrating the survival curve from 0 to positive infinity (or equivalently to the maximum lifespan, sometimes called 'omega'). For an extinct or completed cohort (all people born in the year 1850, for example), it can of course simply be calculated by averaging the ages at death. For cohorts with some survivors, it is estimated by using mortality experience in recent years. The estimates are called period cohort life expectancies.

The starting point for calculating life expectancy is the age-specific death rates of the population members. If a large amount of data is available, a statistical population can be created that allow the age-specific death rates to be simply taken as the mortality rates actually experienced at each age (the number of deaths divided by the number of years "exposed to risk" in each data cell). However, it is customary to apply smoothing to remove (as much as possible) the random statistical fluctuations from one year of age to the next. In the past, a very simple model used for this purpose was the Gompertz function, but more sophisticated methods are now used.[144] The most common modern methods include:

  • fitting a mathematical formula (such as the Gompertz function, or an extension of it) to the data.
  • looking at an established mortality table derived from a larger population and making a simple adjustment to it (such as multiplying by a constant factor) to fit the data. (In cases of relatively small amounts of data.)
  • looking at the mortality rates actually experienced at each age and applying a piecewise model (such as by cubic splines) to fit the data. (In cases of relatively large amounts of data.)

The age-specific death rates are calculated separately for separate groups of data that are believed to have different mortality rates (such as males and females, or smokers and non-smokers) and are then used to calculate a life table from which one can calculate the probability of surviving to each age. While the data required are easily identified in the case of humans, the computation of life expectancy of industrial products and wild animals involves more indirect techniques. The life expectancy and demography of wild animals are often estimated by capturing, marking, and recapturing them.[145] The life of a product, more often termed shelf life, is also computed using similar methods. In the case of long-lived components, such as those used in critical applications (e.g. aircraft), methods like accelerated aging are used to model the life expectancy of a component.[8]

It is important to note that the life expectancy statistic is usually based on past mortality experience and assumes that the same age-specific mortality rates will continue. Thus, such life expectancy figures need to be adjusted for temporal trends before calculating how long a currently living individual of a particular age is expected to live. Period life expectancy remains a commonly used statistic to summarize the current health status of a population. However, for some purposes, such as pensions calculations, it is usual to adjust the life table used by assuming that age-specific death rates will continue to decrease over the years, as they have usually done in the past. That is often done by simply extrapolating past trends, but some models exist to account for the evolution of mortality, like the Lee–Carter model.[146]

As discussed above, on an individual basis, some factors correlate with longer life. Factors that are associated with variations in life expectancy include family history, marital status, economic status, physique, exercise, diet, drug use (including smoking and alcohol consumption), disposition, education, environment, sleep, climate, and health care.[9]

Healthy life expectancy

To assess the quality of these additional years of life, 'healthy life expectancy' has been calculated for the last 30 years. Since 2001, the World Health Organization has published statistics called Healthy life expectancy (HALE), defined as the average number of years that a person can expect to live in "full health" excluding the years lived in less than full health due to disease and/or injury.[147][148] Since 2004, Eurostat publishes annual statistics called Healthy Life Years (HLY) based on reported activity limitations. The United States uses similar indicators in the framework of the national health promotion and disease prevention plan "Healthy People 2010". More and more countries are using health expectancy indicators to monitor the health of their population.

The long-standing quest for longer life led in the 2010s to a more promising focus on increasing HALE, also known as a person's "healthspan". Besides the benefits of keeping people healthier longer, a goal is to reduce health-care expenses on the many diseases associated with cellular senescence. Approaches being explored include fasting, exercise, and senolytic drugs.[149]

Forecasting

Forecasting life expectancy and mortality form an important subdivision of demography. Future trends in life expectancy have huge implications for old-age support programs (like U.S. Social Security and pension) since the cash flow in these systems depends on the number of recipients who are still living (along with the rate of return on the investments or the tax rate in pay-as-you-go systems). With longer life expectancies, the systems see increased cash outflow; if the systems underestimate increases in life-expectancies, they will be unprepared for the large payments that will occur, as humans live longer and longer.

Life expectancy forecasting is usually based on one of two different approaches:

  1. Forecasting the life expectancy directly, generally using ARIMA or other time-series extrapolation procedures. This has the advantage of simplicity, but it cannot account for changes in mortality at specific ages, and the forecast number cannot be used to derive other life table results. Analyses and forecasts using this approach can be done with any common statistical/mathematical software package, like EViews, R, SAS, Stata, Matlab, or SPSS.
  2. Forecasting age-specific death rates and computing the life expectancy from the results with life table methods. This is usually more complex than simply forecasting life expectancy because the analyst must deal with correlated age-specific mortality rates, but it seems to be more robust than simple one-dimensional time series approaches. It also yields a set of age-specific rates that may be used to derive other measures, such as survival curves or life expectancies at different ages. The most important approach in this group is the Lee-Carter model,[150] which uses the singular value decomposition on a set of transformed age-specific mortality rates to reduce their dimensionality to a single time series, forecasts that time series, and then recovers a full set of age-specific mortality rates from that forecasted value. The software includes Professor Rob J. Hyndman's and UC Berkeley's LCFIT system.

Policy uses

Life expectancy is one of the factors in measuring the Human Development Index (HDI) of each nation along with adult literacy, education, and standard of living.[151]

Life expectancy is used in describing the physical quality of life of an area. It is also used for an individual when the value of a life settlement is determined a life insurance policy is sold for a cash asset.[clarification needed]

Disparities in life expectancy are often cited as demonstrating the need for better medical care or increased social support. A strongly associated indirect measure is income inequality. For the top 21 industrialized countries, if each person is counted equally, life expectancy is lower in more unequal countries (r = −0.907).[152] There is a similar relationship among states in the U.S. (r = −0.620).[153]

Life expectancy vs. maximum life span

Life expectancy is commonly confused with the average age an adult could expect to live. This confusion may create the expectation that an adult would be unlikely to exceed an average life expectancy, even though, with all statistical probability, an adult, who has already avoided many statistical causes of adolescent mortality, should be expected to outlive the average life expectancy calculated from birth.[154] One must compare the life expectancy of the period after childhood to estimate also the life expectancy of an adult.[154] Life expectancy can change dramatically after childhood, even in preindustrial times as is demonstrated by the Roman Life Expectancy table[clarification needed], which estimates life expectancy to be 25 years at birth, but 53 years upon reaching age 25.[155][full citation needed] Additional studies similarly show a dramatic increase in life expectancy once adulthood was reached.[156][157]

Life expectancy differs from maximum life span. Life expectancy is an average for all people in the population—including those who die shortly after birth, those who die in early adulthood (e.g. childbirth, war), and those who live unimpeded until old age. Maximum lifespan is an individual-specific concept, and therefore is an upper bound rather than an average.[154] Science author Christopher Wanjek writes, "[H]as the human race increased its life span? Not at all. This is one of the biggest misconceptions about old age: we are not living any longer." The maximum life span, or oldest age a human can live, may be constant.[154] Further, there are many examples of people living significantly longer than the average life expectancy of their time period, such as Socrates (71), Saint Anthony the Great (105), Michelangelo (88), and John Adams (90).[154]

However, anthropologist John D. Hawks criticizes the popular conflation of life span (life expectancy) and maximum life span when popular science writers falsely imply that the average adult human does not live longer than their ancestors. He writes, "[a]ge-specific mortality rates have declined across the adult lifespan. A smaller fraction of adults die at 20, at 30, at 40, at 50, and so on across the lifespan. As a result, we live longer on average... In every way we can measure, human lifespans are longer today than in the immediate past, and longer today than they were 2000 years ago... age-specific mortality rates in adults really have reduced substantially."[158]

See also

Increasing life expectancy

Notes

  1. ^ a b In standard actuarial notation, ex refers to the expected future lifetime of (x) in whole years, while x (with a ring above the e) denotes the complete expected future lifetime of (x), including the fraction.
  2. ^ Japan's recorded life expectancy may have been very slightly increased by counting many infant deaths as stillborn.[55]
  3. ^ Note the different units: a probability is unit-less, whereas a mortality rate has units (such as deaths per population per year).

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Further reading

External links

  • Charts for all countries
  • —Visualizations of how life expectancy around the world has changed historically (by Max Roser). Includes life expectancy for different age groups. Charts for all countries, world maps, and links to more data sources.
  • Global Agewatch has the latest internationally comparable statistics on life expectancy from 195 countries.
  • Rank Order—Life expectancy at birth December 29, 2018, at the Wayback Machine from the CIA's World Factbook.
  • Annual Life Tables since 1966; Decennial Life Tables since 1890 from the US Centers for Disease Controls and Prevention, National Center for Health Statistics.
  • from the University of Texas.
  • Animal lifespans: from Tesarta Online (Internet Archive); The Life Span of Animals from Dr. Bob's All Creatures Site.

life, expectancy, this, article, about, normal, lifespan, novel, life, expectancy, novel, human, lifespan, redirects, here, lifespan, person, stages, maturation, this, article, require, cleanup, meet, wikipedia, quality, standards, specific, problem, clarifica. This article is about normal lifespan For the novel see Life Expectancy novel Human lifespan redirects here For the lifespan of a person in stages see Maturation This article may require cleanup to meet Wikipedia s quality standards The specific problem is Clarification needed at times Please help improve this article if you can November 2022 Learn how and when to remove this template message Life expectancy is a statistical measure of the average time an organism is expected to live based on the year of its birth current age and other demographic factors like sex The most commonly used measure is life expectancy at birth LEB which can be defined in two ways Cohort LEB is the mean length of life of a birth cohort all individuals born in a given year and can be computed only for cohorts born so long ago that all their members have died Period LEB is the mean length of life of a hypothetical cohort 1 2 assumed to be exposed from birth through death to the mortality rates observed at a given year 3 Life expectancy in USA China and Russia 1960 2020 Life expectancy in the largest European countries 1960 2020 Life expectancy at birth measured by region between 1950 and 2050 Life expectancy by world region from 1770 to 2018 Gender Die Gap global gender life expectancy gap at birth for countries and territories as defined by WHO for 2019 Open the original svg file and hover over a bubble to show its data The square of the bubbles is proportional to country population based on estimation of the UN National LEB figures reported by national agencies and international organizations for human populations are estimates of period LEB In the Bronze Age and the Iron Age human LEB was 26 years in 2010 world LEB was 67 2 years In recent years LEB in Eswatini formerly Swaziland is 49 while LEB in Japan is 83 The combination of high infant mortality and deaths in young adulthood from accidents epidemics plagues wars and childbirth before modern medicine was widely available significantly lowers LEB For example a society with a LEB of 40 would have relatively few people dying at exactly 40 most will die before 30 or after 55 In populations with high infant mortality rates LEB is highly sensitive to the rate of death in the first few years of life Because of this sensitivity LEB can be grossly misinterpreted leading to the belief that a population with a low LEB would have a small proportion of older people 4 A different measure such as life expectancy at age 5 e5 can be used to exclude the effect of infant mortality to provide a simple measure of overall mortality rates other than in early childhood For instance in a society with a life expectancy of 30 it may nevertheless be common to have a 40 year remaining timespan at age 5 but perhaps not a 60 year one Until the middle of the 20th century infant mortality was approximately 40 60 of the total mortality Excluding child mortality the average life expectancy during the 12th 19th centuries was approximately 55 years If a person survived childhood they had about a 50 chance of living 50 55 years instead of only 25 40 years 5 Aggregate population measures such as the proportion of the population in various age groups are also used alongside individual based measures such as formal life expectancy when analyzing population structure and dynamics Pre modern societies had universally higher mortality rates and lower life expectancies at every age for both males and females This example is relatively rare Life expectancy longevity and maximum lifespan are not synonymous Longevity refers to the relatively long lifespan of some members of a population Maximum lifespan is the age at death for the longest lived individual of a species Mathematically life expectancy is denoted e x displaystyle e x a and is the mean number of years of life remaining at a given age x displaystyle x with a particular mortality 6 Because life expectancy is an average a particular person may die many years before or after the expected survival Life expectancy is also used in plant or animal ecology 7 and in life tables also known as actuarial tables The concept of life expectancy may also be used in the context of manufactured objects 8 though the related term dubious discuss shelf life is commonly used for consumer products and the terms mean time to breakdown MTTB and mean time between failures MTBF are used in engineering Contents 1 Human patterns 1 1 Maximum 1 2 Variation over time 1 3 Regional variations 1 4 Economic circumstances 1 5 Sex differences 1 6 Genetics 1 7 Centenarians 1 8 Mental illness 1 9 Other illnesses 1 10 Education 2 Evolution and aging rate 3 Calculation 4 Healthy life expectancy 5 Forecasting 6 Policy uses 7 Life expectancy vs maximum life span 8 See also 8 1 Increasing life expectancy 9 Notes 10 References 11 Further reading 12 External linksHuman patterns EditMaximum Edit The longest verified lifespan for any human is that of Frenchwoman Jeanne Calment who is verified as having lived to age 122 years 164 days between 21 February 1875 and 4 August 1997 This is referred to as the maximum life span which is the upper boundary of life the maximum number of years any human is known to have lived 9 A theoretical study shows that the maximum life expectancy at birth is limited by the human life characteristic value d which is around 104 years 10 According to a study by biologists Bryan G Hughes and Siegfried Hekimi there is no evidence for limit on human lifespan 11 12 However this view has been questioned on the basis of error patterns 13 Records of human lifespan above age 100 are highly susceptible to errors 13 For example the previous world record holder for human lifespan Carrie C White was uncovered as a simple typographic error after more than two decades 13 failed verification Variation over time Edit Further information Longevity and List of countries by past life expectancy The following information is derived from the 1961 Encyclopaedia Britannica and other sources some with questionable accuracy Unless otherwise stated it represents estimates of the life expectancies of the world population as a whole In many instances life expectancy varied considerably according to class and gender Life expectancy at birth takes account of infant mortality and child mortality but not prenatal mortality Era Life expectancy at birth in years NotesPaleolithic 22 33 14 Based on the data from modern hunter gatherer populations it is estimated that at 15 life expectancy was an additional 39 years total 54 with a 60 probability of reaching 15 15 Neolithic 20 16 33 17 Based on Early Neolithic data total life expectancy at 15 would be 28 33 years 18 Bronze Age and Iron Age 19 26 Based on Early and Middle Bronze Age data total life expectancy at 15 would be 28 36 years 18 Classical Greece 20 25 21 28 22 Based on Athens Agora and Corinth data total life expectancy at 15 would be 37 41 years 18 Most Greeks and Romans died young About half of all children died before adolescence Those who survived to the age of 30 had a reasonable chance of reaching 50 or 60 The truly elderly however were rare Because so many died in childhood life expectancy at birth was probably between 20 and 30 years 23 Classical Rome 20 33 24 25 26 23 14 27 Data is lacking but computer models provide the estimate If a person survived to age 20 they could expect to live around 30 years more Life expectancy was probably slightly longer for women than men 28 When infant mortality is factored out i e counting only the 67 24 75 who survived the first year life expectancy is around 34 41 more years i e expected to live to 35 42 When child mortality is factored out i e counting only the 55 65 who survived to age 5 life expectancy is around 40 45 i e age 45 50 26 The 50 that reached age 10 could also expect to reach 45 50 24 at 15 to 48 54 at 40 to 60 24 at 50 to 64 68 at 60 to 70 72 at 70 to 76 77 26 28 Vedic India 50 50 75 was considered the average lifespan by Vedic texts 29 Ancient Ayurveda focused on cleaning body boiling water before drinking and similar modern sanitisation practices Wang clan of China 1st c AD 1749 35 For the 60 that survived the first year i e excluding infant mortalities life expectancy rose to 35 30 31 Early Middle Ages Europe from the late 5th or early 6th century to the 10th century 30 35 Life expectancy for those of both sexes who survived birth averaged about 30 35 years However if a Gaulish boy made it past age 20 he might expect to live 25 more years while a woman at age 20 could normally expect about 17 more years Anyone who survived until 40 had a good chance at another 15 to 20 years 32 Pre Columbian Mesoamerica 33 gt 40 The average Aztec life expectancy was 41 2 years for men and 42 1 for women Late medieval English peerage 34 35 30 33 27 In Europe around one third of infants died in their first year 14 Once children reached the age of 10 their life expectancy was 32 2 years and for those who survived to 25 the remaining life expectancy was 23 3 years Such estimates reflected the life expectancy of adult males from the higher ranks of English society in the Middle Ages and were similar to that computed for monks of the Christ Church in Canterbury during the 15th century 27 At age 21 life expectancy of an aristocrat was an additional 43 years total age 64 36 Early modern England 16th 18th century 19 33 40 For males in the 18th century it was 34 years 37 For 15 year old girls around the 15th 16th century it was 33 years 48 total and in the 18th century it was 42 57 total 38 18th century England 39 14 25 40 For most of the century it ranged from 35 to 40 however in the 1720s it dipped as low as 25 39 For 15 year old girls it was 42 57 total 38 During the second half of the century it was 37 40 while for the elite it passed 40 and approached 50 30 Pre Champlain Canadian Maritimes 41 60 Samuel de Champlain wrote that in his visits to Mi kmaq and Huron communities he met people over 100 years old Daniel Paul attributes the incredible lifespan in the region to low stress and a healthy diet of lean meats diverse vegetables and legumes 42 18th century Prussia 37 24 7 For males 37 18th century France 37 27 5 30 For males 37 24 8 years in 1740 1749 27 9 years in 1750 1759 33 9 years in 1800 1809 31 18th century American colonies 14 28 Massachusetts colonists who reached the age of 50 could expect to live until 71 and those who were still alive at 60 could expect to reach 75 Beginning of the 19th century 39 29 Demographic research suggests that at the beginning of the 19th century no country in the world had a life expectancy longer than 40 years India was 25 years while Belgium was 40 years 39 For Europe as a whole it was 33 years 40 Early 19th century England 19 39 30 40 For the 84 who survived the first year i e excluding infant mortality the average age was 46 30 48 If they reached 20 then it was 60 if 50 then 70 if 70 then 80 39 For a 15 year old girl it was 60 65 38 For the upper class LEB rose from 45 to 50 30 Less than half of the people born in the mid 19th century made it past their 50th birthday In contrast 97 of the people born in 21st century England and Wales can expect to live longer than 50 years 39 19th century British India 43 25 419th century world average 39 28 5 32 Over the course of the century Europe rose from 33 to 43 the Americas from 35 to 41 Oceania 35 to 48 Asia 28 Africa 26 39 In 1820s France LEB was 38 and for the 80 that survived it rose to 47 For Moscow serfs LEB was 34 and for the 66 that survived it rose to 36 30 Western Europe in 1830 was 33 years while for the people of Hau Lou in China it was 40 40 The LEB for a 10 year old in Sweden rose from 44 to 54 39 1900 world average 44 31 32 39 Around 48 years in Oceania 43 in Europe and 41 in the Americas 39 Around 47 in the U S 14 and around 48 for 15 year old girls in England 38 1950 world average 44 45 7 48 39 Around 60 years in Europe North America Oceania Japan and parts of South America but only 41 in Asia and 36 in Africa Norway led with 72 while in Mali it was merely 26 39 2019 2020 world average 72 6 73 2 39 45 46 Females 75 6 years Males 70 8 years Range 54 Central African Republic 85 3 Hong Kong 46 Life expectancy increases with age as the individual survives the higher mortality rates associated with childhood For instance the table above gives the life expectancy at birth among 13th century English nobles at 30 Having survived to the age of 21 a male member of the English aristocracy in this period could expect to live 36 1200 1300 to age 64 1300 1400 to age 45 because of the bubonic plague 1400 1500 to age 69 1500 1550 to age 7117th century English life expectancy was only about 35 years largely because infant and child mortality remained high Life expectancy was under 25 years in the early Colony of Virginia 47 and in seventeenth century New England about 40 died before reaching adulthood 48 During the Industrial Revolution the life expectancy of children increased dramatically 49 The under 5 mortality rate in London decreased from 74 5 in 1730 1749 to 31 8 in 1810 1829 50 51 Public health measures are credited with much of the recent increase in life expectancy During the 20th century despite a brief drop due to the 1918 flu pandemic 52 the average lifespan in the United States increased by more than 30 years of which 25 years can be attributed to advances in public health 53 Regional variations Edit Further information List of countries by life expectancy Life expectancy in 1800 1950 and 2015 visualization by Our World in Data Human beings are expected to live on average 30 40 years in Eswatini 54 and 82 6 years in Japan b An analysis published in 2011 in The Lancet attributes Japanese life expectancy to equal opportunities public health and diet 56 57 Plot of life expectancy vs GDP per capita in 2009 This phenomenon is known as the Preston curve Graphs of life expectancy at birth for some sub Saharan countries showing the fall in the 1990s primarily due to the HIV pandemic 58 There are great variations in life expectancy between different parts of the world mostly caused by differences in public health medical care and diet The impact of AIDS on life expectancy is particularly notable in many African countries According to projections made by the United Nations in 2002 the life expectancy at birth for 2010 2015 if HIV AIDS did not exist would have been 59 70 7 years instead of 31 6 years Botswana 69 9 years instead of 41 5 years South Africa 70 5 years instead of 31 8 years ZimbabweActual life expectancy in Botswana declined from 65 in 1990 to 49 in 2000 before increasing to 66 in 2011 In South Africa life expectancy was 63 in 1990 57 in 2000 and 58 in 2011 And in Zimbabwe life expectancy was 60 in 1990 43 in 2000 and 54 in 2011 60 During the last 200 years African countries have generally not had the same improvements in mortality rates that have been enjoyed by countries in Asia Latin America and Europe 61 62 In the United States African American people have shorter life expectancies than their European American counterparts For example white Americans in 2010 are expected to live until age 78 9 but black Americans only until age 75 1 This 3 8 year gap however is the lowest it has been since 1975 at the latest The greatest difference was 7 1 years in 1993 63 In contrast Asian American women live the longest of all ethnic groups in the United States with a life expectancy of 85 8 years 64 The life expectancy of Hispanic Americans is 81 2 years 63 According to the new government reports in the US life expectancy in the country dropped again because of the rise in suicide and drug overdose rates The Centers for Disease Control CDC found nearly 70 000 more Americans died in 2017 than in 2016 with rising rates of death among 25 to 44 year olds 65 Cities also experience a wide range of life expectancy based on neighborhood breakdowns This is largely due to economic clustering and poverty conditions that tend to associate based on geographic location Multi generational poverty found in struggling neighborhoods also contributes In United States cities such as Cincinnati the life expectancy gap between low income and high income neighborhoods touches 20 years 66 Economic circumstances Edit Life expectancy is higher in rich countries with low economic inequality 67 Life expectancy vs healthcare spending of rich OECD countries 68 Economic circumstances also affect life expectancy For example in the United Kingdom life expectancy in the wealthiest and richest areas is several years higher than in the poorest areas This may reflect factors such as diet and lifestyle as well as access to medical care It may also reflect a selective effect people with chronic life threatening illnesses are less likely to become wealthy or to reside in affluent areas 69 In Glasgow the disparity is amongst the highest in the world life expectancy for males in the heavily deprived Calton area stands at 54 which is 28 years less than in the affluent area of Lenzie which is only 8 km 5 0 mi away 70 71 A 2013 study found a pronounced relationship between economic inequality and life expectancy 72 However in contrast a study by Jose A Tapia Granados and Ana Diez Roux at the University of Michigan found that life expectancy actually increased during the Great Depression and during recessions and depressions in general 73 The authors suggest that when people are working at a more extreme degree during prosperous economic times they undergo more stress exposure to pollution and the likelihood of injury among other longevity limiting factors Life expectancy is also likely to be affected by exposure to high levels of highway air pollution or industrial air pollution This is one way that occupation can have a major effect on life expectancy Coal miners and in prior generations asbestos cutters often have lower life expectancies than average Other factors affecting an individual s life expectancy are genetic disorders drug use tobacco smoking excessive alcohol consumption obesity access to health care diet and exercise Sex differences Edit Pink Countries where female life expectancy at birth is higher than males Blue A few countries in southern Africa where females have shorter lives due to AIDS 74 In the present female human life expectancy is greater than that of males despite females having higher morbidity rates see Health Survival paradox There are many potential reasons for this Traditional arguments tend to favor sociology environmental factors historically men have generally consumed more tobacco alcohol and drugs than women in most societies and are more likely to die from many associated diseases such as lung cancer tuberculosis and cirrhosis of the liver 75 Men are also more likely to die from injuries whether unintentional such as occupational war or car accidents or intentional suicide 75 Men are also more likely to die from most of the leading causes of death some already stated above than women Some of these in the United States include cancer of the respiratory system motor vehicle accidents suicide cirrhosis of the liver emphysema prostate cancer and coronary heart disease 9 These far outweigh the female mortality rate from breast cancer and cervical cancer In the past mortality rates for females in child bearing age groups were higher than for males at the same age A paper from 2015 found that female fetuses have a higher mortality rate than male fetuses 76 This finding contradicts papers dating from 2002 and earlier that attribute the male sex to higher in utero mortality rates 77 78 79 Among the smallest premature babies those under 2 pounds 910 grams females have a higher survival rate At the other extreme about 90 of individuals aged 110 are female The difference in life expectancy between men and women in the United States dropped from 7 8 years in 1979 to 5 3 years in 2005 with women expected to live to age 80 1 in 2005 80 Data from the United Kingdom shows the gap in life expectancy between men and women decreasing in later life This may be attributable to the effects of infant mortality and young adult death rates 81 Some argue that shorter male life expectancy is merely another manifestation of the general rule seen in all mammal species that larger sized individuals within a species tend on average to have shorter lives 82 83 This biological difference clarification needed occurs because women have more resistance to infections and degenerative diseases 9 In her extensive review of the existing literature Kalben concluded that the fact that women live longer than men was observed at least as far back as 1750 and that with relatively equal treatment today males in all parts of the world experience greater mortality than females However Kalben s study was restricted to data in Western Europe alone where the demographic transition occurred relatively early United Nations statistics from mid twentieth century onward show that in all parts of the world females have a higher life expectancy at age 60 than males 84 Of 72 selected causes of death only 6 yielded greater female than male age adjusted death rates in 1998 in the United States Except for birds for almost all of the animal species studied males have higher mortality than females Evidence suggests that the sex mortality differential in people is due to both biological genetic and environmental behavioral risk and protective factors 85 One recent suggestion is that mitochondrial mutations which shorten lifespan continue to be expressed in males but less so in females because mitochondria are inherited only through the mother By contrast natural selection weeds out mitochondria that reduce female survival therefore such mitochondria are less likely to be passed on to the next generation This thus suggests that females tend to live longer than males The authors claim that this is a partial explanation 86 87 Another explanation is the unguarded X hypothesis According to this hypothesis one reason for why the average lifespan of males isn t as long as that of females by 18 on average according to the study is that they have a Y chromosome which can t protect an individual from harmful genes expressed on the X chromosome while a duplicate X chromosome as present in female organisms can ensure harmful genes aren t expressed 88 89 Before the Industrial Revolution men lived longer than women on average 90 91 In developed countries starting around 1880 death rates decreased faster among women leading to differences in mortality rates between males and females Before 1880 death rates were the same In people born after 1900 the death rate of 50 to 70 year old men was double that of women of the same age Men may be more vulnerable to cardiovascular disease than women but this susceptibility was evident only after deaths from other causes such as infections started to decline 92 Most of the difference in life expectancy between the sexes is accounted for by differences in the rate of death by cardiovascular diseases among persons aged 50 70 93 Genetics Edit Further information Genetics of aging The heritability of lifespan is estimated to be less than 10 meaning the majority of variation in lifespan is attributable due to differences in environment rather than genetic variation 94 However researchers have identified regions of the genome which can influence the length of life and the number of years lived in good health For example a genome wide association study of 1 million lifespans found 12 genetic loci which influenced lifespan by modifying susceptibility to cardiovascular and smoking related disease 95 The locus with the largest effect is APOE Carriers of the APOE e4 allele live approximately one year less than average per copy of the e4 allele mainly due to increased risk of Alzheimer s disease 95 Healthspan parental lifespan and longevity are highly genetically correlated 96 In July 2020 scientists identified 10 genomic loci with consistent effects across multiple lifespan related traits including healthspan lifespan and longevity 96 The genes affected by variation in these loci highlighted haem metabolism as a promising candidate for further research within the field This study suggests that high levels of iron in the blood likely reduce and genes involved in metabolising iron likely increase healthy years of life in humans 97 A follow up study which investigated the genetics of frailty and self rated health in addition to healthspan lifespan and longevity also highlighted haem metabolism as an important pathway and found genetic variants which lower blood protein levels of LPA and VCAM1 were associated with increased healthy lifespan 98 Centenarians Edit Main article Centenarian In developed countries the number of centenarians is increasing at approximately 5 5 per year which means doubling the centenarian population every 13 years pushing it from some 455 000 in 2009 to 4 1 million in 2050 99 Japan is the country with the highest ratio of centenarians 347 for every 1 million inhabitants in September 2010 Shimane Prefecture had an estimated 743 centenarians per million inhabitants 100 In the United States the number of centenarians grew from 32 194 in 1980 to 71 944 in November 2010 232 centenarians per million inhabitants 101 Mental illness Edit Mental illness is reported to occur in approximately 18 of the average American population 102 103 Life expectancy in the seriously mentally ill is much shorter than the general population 104 The mentally ill have been shown to have a 10 to 25 year reduction in life expectancy 105 Generally the reduction of lifespan in the mentally ill population compared to the mentally stable population has been studied and documented 106 107 108 109 110 The greater mortality of people with mental disorders may be due to death from injury from co morbid conditions or medication side effects 111 For instance psychiatric medications can increase the risk of developing diabetes 112 113 114 115 It has been shown that the psychiatric medication olanzapine can increase risk of developing agranulocytosis among other comorbidities 116 117 Psychiatric medicines also affect the gastrointestinal tract the mentally ill have a four times risk of gastrointestinal disease 118 119 120 As of 2020 and the COVID 19 pandemic researchers have found an increased risk of death in the mentally ill 121 122 123 Other illnesses Edit The life expectancy of people with diabetes which is 9 3 of the U S population is reduced by roughly 10 20 years 124 125 People over 60 years old with Alzheimer s disease have about a 50 life expectancy of 3 10 years 126 Other demographics that tend to have a lower life expectancy than average include transplant recipients 127 and the obese 128 Education Edit Education on all levels has been shown to be strongly associated with increased life expectancy 129 This association may be due partly to higher income 130 which can lead to increased life expectancy Despite the association among identical twin pairs with different education levels there is only weak evidence of a relationship between educational attainment and adult mortality 129 According to a paper from 2015 the mortality rate for the Caucasian population in the United States from 1993 to 2001 is four times higher dubious discuss for those who did not complete high school compared to those who have at least 16 years of education 129 In fact within the U S adult population people with less than a high school education have the shortest life expectancies Preschool education also plays a large role in life expectancy It was found that high quality early stage childhood education had positive effects on health Researchers discovered this by analyzing the results of the Carolina Abecedarian Project finding that the disadvantaged children who were randomly assigned to treatment had lower instances of risk factors for cardiovascular and metabolic diseases in their mid 30s 131 Evolution and aging rate EditMain article Life history theory Various species of plants and animals including humans have different lifespans Evolutionary theory states that organisms which by virtue of their defenses or lifestyle live for long periods and avoid accidents disease predation etc are likely to have genes that code for slow aging which often translates to good cellular repair One theory is that if predation or accidental deaths prevent most individuals from living to an old age there will be less natural selection to increase the intrinsic life span 132 That finding was supported in a classic study of opossums by Austad 133 however the opposite relationship was found in an equally prominent study of guppies by Reznick 134 135 One prominent and very popular theory states that lifespan can be lengthened by a tight budget for food energy called caloric restriction 136 Caloric restriction observed in many animals most notably mice and rats shows a near doubling of life span from a very limited calorific intake Support for the theory has been bolstered by several new studies linking lower basal metabolic rate to increased life expectancy 137 138 139 That is the key to why animals like giant tortoises can live so long 140 Studies of humans with life spans of at least 100 have shown a link to decreased thyroid activity resulting in their lowered metabolic rate citation needed In a broad survey of zoo animals no relationship was found between investment of the animal in reproduction and its life span 141 Calculation EditFurther information Life table The mathematics A survival tree to explain the calculations of life expectancy Red numbers indicate a chance of survival at a specific age and blue ones indicate age specific death rates In actuarial notation the probability of surviving from age x displaystyle x to age x n displaystyle x n is denoted n p x displaystyle n p x and the probability of dying during age x displaystyle x i e between ages x displaystyle x and x 1 displaystyle x 1 is denoted q x displaystyle q x For example if 10 of a group of people alive at their 90th birthday die before their 91st birthday the age specific death probability at 90 would be 10 This probability describes the likelihood of dying at that age and is not the rate at which people of that age die c It can be shown thatk p x q x k k p x k 1 p x displaystyle k p x q x k k p x k 1 p x 1 The curtate future lifetime denoted K x displaystyle K x is a discrete random variable representing the remaining lifetime at age x displaystyle x rounded down to whole years Life expectancy more technically called the curtate expected lifetime and denoted e x displaystyle e x a is the mean of K x displaystyle K x that is to say the expected number of whole years of life remaining assuming survival to age x displaystyle x 142 So e x E K x k 0 k Pr K x k k 0 k k p x q x k displaystyle e x operatorname E K x sum k 0 infty k cdot Pr K x k sum k 0 infty k k p x q x k 2 Substituting 1 into the sum and simplifying gives the final result 143 e x k 1 k p x displaystyle e x sum k 1 infty k p x 3 If the assumption is made that on average people live a half year on the year of their death the complete life expectancy at age x displaystyle x would be e x 1 2 displaystyle e x 1 2 By definition life expectancy is an arithmetic mean It can also be calculated by integrating the survival curve from 0 to positive infinity or equivalently to the maximum lifespan sometimes called omega For an extinct or completed cohort all people born in the year 1850 for example it can of course simply be calculated by averaging the ages at death For cohorts with some survivors it is estimated by using mortality experience in recent years The estimates are called period cohort life expectancies The starting point for calculating life expectancy is the age specific death rates of the population members If a large amount of data is available a statistical population can be created that allow the age specific death rates to be simply taken as the mortality rates actually experienced at each age the number of deaths divided by the number of years exposed to risk in each data cell However it is customary to apply smoothing to remove as much as possible the random statistical fluctuations from one year of age to the next In the past a very simple model used for this purpose was the Gompertz function but more sophisticated methods are now used 144 The most common modern methods include fitting a mathematical formula such as the Gompertz function or an extension of it to the data looking at an established mortality table derived from a larger population and making a simple adjustment to it such as multiplying by a constant factor to fit the data In cases of relatively small amounts of data looking at the mortality rates actually experienced at each age and applying a piecewise model such as by cubic splines to fit the data In cases of relatively large amounts of data The age specific death rates are calculated separately for separate groups of data that are believed to have different mortality rates such as males and females or smokers and non smokers and are then used to calculate a life table from which one can calculate the probability of surviving to each age While the data required are easily identified in the case of humans the computation of life expectancy of industrial products and wild animals involves more indirect techniques The life expectancy and demography of wild animals are often estimated by capturing marking and recapturing them 145 The life of a product more often termed shelf life is also computed using similar methods In the case of long lived components such as those used in critical applications e g aircraft methods like accelerated aging are used to model the life expectancy of a component 8 It is important to note that the life expectancy statistic is usually based on past mortality experience and assumes that the same age specific mortality rates will continue Thus such life expectancy figures need to be adjusted for temporal trends before calculating how long a currently living individual of a particular age is expected to live Period life expectancy remains a commonly used statistic to summarize the current health status of a population However for some purposes such as pensions calculations it is usual to adjust the life table used by assuming that age specific death rates will continue to decrease over the years as they have usually done in the past That is often done by simply extrapolating past trends but some models exist to account for the evolution of mortality like the Lee Carter model 146 As discussed above on an individual basis some factors correlate with longer life Factors that are associated with variations in life expectancy include family history marital status economic status physique exercise diet drug use including smoking and alcohol consumption disposition education environment sleep climate and health care 9 Healthy life expectancy EditTo assess the quality of these additional years of life healthy life expectancy has been calculated for the last 30 years Since 2001 the World Health Organization has published statistics called Healthy life expectancy HALE defined as the average number of years that a person can expect to live in full health excluding the years lived in less than full health due to disease and or injury 147 148 Since 2004 Eurostat publishes annual statistics called Healthy Life Years HLY based on reported activity limitations The United States uses similar indicators in the framework of the national health promotion and disease prevention plan Healthy People 2010 More and more countries are using health expectancy indicators to monitor the health of their population The long standing quest for longer life led in the 2010s to a more promising focus on increasing HALE also known as a person s healthspan Besides the benefits of keeping people healthier longer a goal is to reduce health care expenses on the many diseases associated with cellular senescence Approaches being explored include fasting exercise and senolytic drugs 149 Forecasting EditForecasting life expectancy and mortality form an important subdivision of demography Future trends in life expectancy have huge implications for old age support programs like U S Social Security and pension since the cash flow in these systems depends on the number of recipients who are still living along with the rate of return on the investments or the tax rate in pay as you go systems With longer life expectancies the systems see increased cash outflow if the systems underestimate increases in life expectancies they will be unprepared for the large payments that will occur as humans live longer and longer Life expectancy forecasting is usually based on one of two different approaches Forecasting the life expectancy directly generally using ARIMA or other time series extrapolation procedures This has the advantage of simplicity but it cannot account for changes in mortality at specific ages and the forecast number cannot be used to derive other life table results Analyses and forecasts using this approach can be done with any common statistical mathematical software package like EViews R SAS Stata Matlab or SPSS Forecasting age specific death rates and computing the life expectancy from the results with life table methods This is usually more complex than simply forecasting life expectancy because the analyst must deal with correlated age specific mortality rates but it seems to be more robust than simple one dimensional time series approaches It also yields a set of age specific rates that may be used to derive other measures such as survival curves or life expectancies at different ages The most important approach in this group is the Lee Carter model 150 which uses the singular value decomposition on a set of transformed age specific mortality rates to reduce their dimensionality to a single time series forecasts that time series and then recovers a full set of age specific mortality rates from that forecasted value The software includes Professor Rob J Hyndman s R package called demography and UC Berkeley s LCFIT system Policy uses EditLife expectancy is one of the factors in measuring the Human Development Index HDI of each nation along with adult literacy education and standard of living 151 Life expectancy is used in describing the physical quality of life of an area It is also used for an individual when the value of a life settlement is determined a life insurance policy is sold for a cash asset clarification needed Disparities in life expectancy are often cited as demonstrating the need for better medical care or increased social support A strongly associated indirect measure is income inequality For the top 21 industrialized countries if each person is counted equally life expectancy is lower in more unequal countries r 0 907 152 There is a similar relationship among states in the U S r 0 620 153 Life expectancy vs maximum life span EditLife expectancy is commonly confused with the average age an adult could expect to live This confusion may create the expectation that an adult would be unlikely to exceed an average life expectancy even though with all statistical probability an adult who has already avoided many statistical causes of adolescent mortality should be expected to outlive the average life expectancy calculated from birth 154 One must compare the life expectancy of the period after childhood to estimate also the life expectancy of an adult 154 Life expectancy can change dramatically after childhood even in preindustrial times as is demonstrated by the Roman Life Expectancy table clarification needed which estimates life expectancy to be 25 years at birth but 53 years upon reaching age 25 155 full citation needed Additional studies similarly show a dramatic increase in life expectancy once adulthood was reached 156 157 Life expectancy differs from maximum life span Life expectancy is an average for all people in the population including those who die shortly after birth those who die in early adulthood e g childbirth war and those who live unimpeded until old age Maximum lifespan is an individual specific concept and therefore is an upper bound rather than an average 154 Science author Christopher Wanjek writes H as the human race increased its life span Not at all This is one of the biggest misconceptions about old age we are not living any longer The maximum life span or oldest age a human can live may be constant 154 Further there are many examples of people living significantly longer than the average life expectancy of their time period such as Socrates 71 Saint Anthony the Great 105 Michelangelo 88 and John Adams 90 154 However anthropologist John D Hawks criticizes the popular conflation of life span life expectancy and maximum life span when popular science writers falsely imply that the average adult human does not live longer than their ancestors He writes a ge specific mortality rates have declined across the adult lifespan A smaller fraction of adults die at 20 at 30 at 40 at 50 and so on across the lifespan As a result we live longer on average In every way we can measure human lifespans are longer today than in the immediate past and longer today than they were 2000 years ago age specific mortality rates in adults really have reduced substantially 158 See also EditBiodemography Calorie restriction Demography Depreciation DNA damage theory of aging Glasgow effect Healthcare inequality Indefinite lifespan Life table Lindy effect List of countries by life expectancy List of countries by past life expectancy List of longest living organisms Maximum life span Medieval demography Mitohormesis Mortality rate Population pyramid Senescence Increasing life expectancy Edit Strategies for engineered negligible senescence SENS John Sperling Life extension Longevity Rejuvenation Public health Infant mortalityNotes Edit a b In standard actuarial notation ex refers to the expected future lifetime of x in whole years while e x with a ring above the e denotes the complete expected future lifetime of x including the fraction Japan s recorded life expectancy may have been very slightly increased by counting many infant deaths as stillborn 55 Note the different units a probability is unit less whereas a mortality rate has units such as deaths per population per year References Edit Life Expectancy What does this actually mean Our World in Data Retrieved August 31 2020 Period and cohort life expectancy explained December 2019 Office for National Statistics www ons gov uk Retrieved August 31 2020 S Shryock J S Siegel et al The Methods and Materials of Demography Washington DC US Bureau of the Census 1973 Laden Greg May 1 2011 Falsehood If this was the Stone Age I d be dead by now ScienceBlogs Archived from the original on November 11 2012 Retrieved August 31 2014 Felinah Memo Hazara Khan ad Din Old Age Height and Nutrition Common Misconceptions About Medieval England PDF Arthur O Sullivan Steven M Sheffrin 2003 Economics Principles in Action Pearson Prentice Hall p 473 ISBN 978 0 13 063085 8 John S Millar Richard M Zammuto 1983 Life Histories of Mammals An Analysis of Life Tables Ecology Ecological Society of America 64 4 631 635 doi 10 2307 1937181 JSTOR 1937181 a b Eliahu Zahavi Vladimir Torbilo amp Solomon Press 1996 Fatigue Design Life Expectancy of Machine Parts CRC Press ISBN 0 8493 8970 4 a b c d Santrock John 2007 Life Expectancy A Topical Approach to Life Span Development pp 128 132 New York New York The McGraw Hill Companies Inc X Liu 2015 Life equations for the senescence process Biochemistry and Biophysics Reports 4 228 233 arXiv 1502 00759 doi 10 1016 j bbrep 2015 09 020 PMC 5669524 PMID 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1993 We Were Not the Savages A Micmac Perspective on the Collision of European and Aboriginal Civilizations 1st ed Nimbus ISBN 978 1 55109 056 6 Life expectancy Our World in Data Retrieved August 28 2018 a b Prentice Thomson Health history and hard choices Funding dilemmas in a fast changing world PDF World Health Organization Global Health Histories Retrieved November 4 2010 72 6 U N Department of Economic and Social Affairs Population Division World Population Prospects 2019 PDF 72 7 Life expectancy at birth total years Data data worldbank org a b Life Expectancy by Country and in the World Worldometer www worldometers info 1 Stratfordhall org Archived 15 February 2020 at the Wayback Machine Death in Early America Archived December 30 2010 at the Wayback Machine Digital History Modernization Population Change Encyclopaedia Britannica Mabel C Buer Health Wealth and Population in the Early Days of the Industrial Revolution London George Routledge amp Sons 1926 page 30 ISBN 0 415 38218 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healthier for longer New Scientist Retrieved May 2 2019 The Lee Carter Method for Forecasting Mortality with Various Extensions and Applications SOA PDF SOA Retrieved April 9 2018 International Human Development Indicators UNDP Hdrstats undp org Archived from the original on April 20 2009 Retrieved November 4 2010 De Vogli R 2005 Has the relation between income inequality and life expectancy disappeared Evidence from Italy and top industrialised countries Journal of Epidemiology amp Community Health 59 2 158 162 doi 10 1136 jech 2004 020651 PMC 1733006 PMID 15650149 Kaplan G A Pamuk E R Lynch J W Cohen R D Balfour J L 1996 Inequality in income and mortality in the United States analysis of mortality and potential pathways BMJ 312 7037 999 1003 doi 10 1136 bmj 312 7037 999 PMC 2350835 PMID 8616393 a b c d e Wanjek Christopher 2002 Bad Medicine Misconceptions and Misuses Revealed from Distance Healing to Vitamin O Wiley pp 70 71 ISBN 978 0471434993 Frier Demography 789 Common Myths Dead at Forty July 13 2007 Archived from the original on July 13 2007 Life Expectancy by Age 1850 2011 InfoPlease Hawks John 2009 Human lifespans have not been constant for the last 2000 years Further reading EditLeonid A Gavrilov amp Natalia S Gavrilova 1991 The Biology of Life Span A Quantitative Approach New York Harwood Academic Publisher ISBN 3 7186 4983 7 Kochanek Kenneth D Elizabeth Arias and Robert N Anderson 2013 How Did Cause of Death Contribute to Racial Differences in Life Expectancy in the United States in 2010 Hyattsville Md U S Department of Health and Human Services Centers for Disease Control and Prevention National Center for Health Statistics External links Edit Wikimedia Commons has media related to Life expectancy Charts for all countries Our World In Data Life Expectancy Visualizations of how life expectancy around the world has changed historically by Max Roser Includes life expectancy for different age groups Charts for all countries world maps and links to more data sources Global Agewatch has the latest internationally comparable statistics on life expectancy from 195 countries Rank Order Life expectancy at birth Archived December 29 2018 at the Wayback Machine from the CIA s World Factbook Annual Life Tables since 1966 Decennial Life Tables since 1890 from the US Centers for Disease Controls and Prevention National Center for Health Statistics Life expectancy in Roman times from the University of Texas Animal lifespans Animal Lifespans from Tesarta Online Internet Archive The Life Span of Animals from Dr Bob s All Creatures Site Retrieved from https en wikipedia org w index php title Life expectancy amp oldid 1131117716, wikipedia, wiki, book, books, library,

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