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Wikipedia

Lasker Award

The Lasker Awards have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine. They are administered by the Lasker Foundation, which was founded by Albert Lasker and his wife Mary Woodard Lasker (later a medical research activist). The awards are sometimes referred to as "America's Nobels".

Lasker Award
President Lyndon Johnson accepting the special Albert Lasker Award for Leadership in Health
Awarded forMajor contributions to medical science
Sponsored byLasker Foundation
Date1945
Reward(s)$250,000
Highlights
Basic (2019)Max Dale Cooper
Jacques Miller
Clinical (2019)H. Michael Shepard
Dennis J. Slamon
Axel Ullrich
Public Service (2019)GAVI
Websitelaskerfoundation.org

The Lasker Awards have gained a reputation for identifying future winners of the Nobel Prize. Eighty-six Lasker laureates have received the Nobel Prize, including 32 in the last two decades.[1][2] Claire Pomeroy is the current president of the Lasker Foundation.

Award

The award is given in four branches of medical science:[1]

  1. Albert Lasker Basic Medical Research Award
  2. Lasker-DeBakey Clinical Medical Research Award
  3. Lasker-Bloomberg Public Service Award (Renamed in 2011 from Mary Woodard Lasker Public Service Award. Renamed in 2000 from Albert Lasker Public Service Award.)
  4. Lasker-Koshland Special Achievement Award in Medical Science (1994–)(optional)

The awards carry an honorarium of $250,000 for each category.[3]

A collection of papers from the Albert and Mary Lasker Foundation were donated to the National Library of Medicine by Mrs. Albert D. Lasker in April 1985.[4]

In addition to the main awards, there are historical awards that are no longer awarded.[5]

Recent awards

Recent winners include the following:

Year Award Laureate(s) Reason
2022 Basic Richard O. Hynes For discoveries concerning the integrins – key mediators of cell-matrix and cell-cell adhesion in physiology and disease.[6]
Erkki Ruoslahti
Timothy A. Springer
Clinical Yuk Ming Dennis Lo For the discovery of fetal DNA in maternal blood, leading to noninvasive prenatal testing for Down syndrome.[7]
Public Service Lauren Gardner For creating the Covid-19 Dashboard, which set a new standard for disseminating authoritative public health data in real time.[8]
2021 Basic Karl Deisseroth For the discovery of light-sensitive microbial proteins that can activate or silence individual brain cells and for their use in developing optogenetics – a revolutionary technique for neuroscience.[9]
Peter Hegemann
Dieter Oesterhelt
Clinical Katalin Karikó For the discovery of a new therapeutic technology based on the modification of messenger RNA – enabling rapid development of highly effective Covid-19 vaccines.[10]
Drew Weissman
Special Achievement David Baltimore As one of the premier biomedical scientists of the last five decades, he is renowned for the breadth and beauty of his discoveries in virology, immunology, and cancer; for his academic leadership; for his mentorship of prominent scientists; and for his influence as a public advocate for science.[11]
2019 Basic Max Dale Cooper For their discovery of the two distinct classes of lymphocytes, B and T cells – a monumental achievement that provided the organizing principle of the adaptive immune system and launched the course of modern immunology.[12]
Jacques Miller
Clinical H. Michael Shepard For their invention of Herceptin, the first monoclonal antibody that blocks a cancer-causing protein, and for its development as a life-saving therapy for women with breast cancer.[13]
Dennis J. Slamon
Axel Ullrich
Public Service GAVI vaccination alliance For providing sustained access to childhood vaccines around the globe, saving millions of lives, and for highlighting the power of immunization to prevent disease.[14]
2018 Basic C. David Allis For discoveries elucidating how gene expression is influenced by chemical modification of histones – the proteins that package DNA within chromosomes.
Michael Grunstein
Clinical John B. Glen For the discovery and development of propofol, a chemical whose rapid action and freedom from residual effects have made it the most widely used agent for induction of anesthesia in patients throughout the world.
Special Achievement Joan Argetsinger Steitz For four decades of leadership in biomedical science – exemplified by pioneering discoveries in RNA biology, generous mentorship of budding scientists, and vigorous and passionate support of women in science.
2017 Basic Michael N. Hall For discoveries concerning the nutrient-activated TOR proteins and their central role in the metabolic control of cell growth.[15]
Clinical Douglas R. Lowy For technological advances that enabled development of HPV vaccines for prevention of cervical cancer and other tumors caused by human papillomaviruses.
John T. Schiller [de]
Public Service Planned Parenthood For providing essential health services and reproductive care to millions of women for more than a century.
2016 Basic William G. Kaelin Jr. For the discovery of the pathway by which cells from humans and most animals sense and adapt to changes in oxygen availability – a process essential for survival.[16]
Peter J. Ratcliffe
Gregg L. Semenza
Clinical Ralf F. W. Bartenschlager For development of a system to study the replication of the virus that causes hepatitis C and for use of this system to revolutionize the treatment of this chronic, often lethal disease.[17]
Charles M. Rice
Michael J. Sofia
Special Achievement Bruce M. Alberts For fundamental discoveries in DNA replication and protein biochemistry; for visionary leadership in directing national and international scientific organizations to better people’s lives; and for passionate dedication to improving education in science and mathematics.[18]
2015 Basic Stephen J. Elledge For discoveries concerning the DNA-damage response – a fundamental mechanism that protects the genomes of all living organisms.[19]
Evelyn M. Witkin
Clinical James P. Allison For the discovery and development of a monoclonal antibody therapy that unleashes the immune system to combat cancer.[20]
Public Service Médecins Sans Frontières For bold leadership in responding to the recent Ebola outbreak in Africa and for sustained and effective frontline responses to health emergencies.[21]
2014 Basic Kazutoshi Mori For discoveries concerning the unfolded protein response – an intracellular quality control system that detects harmful misfolded proteins in the endoplasmic reticulum and signals the nucleus to carry out corrective measures.
Peter Walter
Clinical Alim-Louis Benabid For the development of deep brain stimulation of the subthalamic nucleus, a surgical technique that reduces tremors and restores motor function in patients with advanced Parkinson's disease.
Mahlon R. DeLong
Special Achievement Mary-Claire King For bold, imaginative, and diverse contributions to medical science and human rights – she discovered the BRCA1 gene locus that causes hereditary breast cancer and deployed DNA strategies that reunite missing persons or their remains with their families.
2013 Basic Richard H. Scheller For discoveries concerning the molecular machinery and regulatory mechanism that underlie the rapid release of neurotransmitters.[22]
Thomas C. Südhof
Clinical Graeme M. Clark For the development of the modern cochlear implant – a device that bestows hearing to individuals with profound deafness.[23]
Ingeborg Hochmair
Blake S. Wilson
Public Service Bill Gates For leading a historic transformation in the way we view the globe's most pressing health concerns and improving the lives of millions of the world's most vulnerable.[24]
Melinda Gates
2012 Basic Michael Sheetz For discoveries concerning cytoskeletal motor proteins, machines that move cargoes within cells, contract muscles, and enable cell movements.[25]
James Spudich
Ronald Vale
Clinical Roy Calne For the development of liver transplantation, which has restored normal life to thousands of patients with end-stage liver disease.[26]
Thomas Starzl
Special Achievement Donald D. Brown For exceptional leadership and citizenship in biomedical science – exemplified by fundamental discoveries concerning the nature of genes; by selfless commitment to young scientists; and by disseminating revolutionary technologies to the scientific community.[27]
Tom Maniatis
2011 Basic Franz-Ulrich Hartl For discoveries concerning the cell's protein-folding machinery, exemplified by cage-like structures that convert newly made proteins into their biologically active forms.[28]
Arthur L. Horwich
Clinical Tu Youyou For the discovery of artemisinin, a drug therapy for malaria that has saved millions of lives across the globe, especially in the developing world.[29]
Public Service National Institutes of Health Clinical Center For serving, since its inception, as a model research hospital – providing innovative therapy and high-quality patient care, treating rare and severe diseases, and producing outstanding physician-scientists whose collective work has set a standard of excellence in biomedical research.[30]
2010 Basic Douglas L. Coleman Discovery of leptin, a hormone that regulates appetite and body weight – a breakthrough that opened obesity research to molecular exploration.[31]
Jeffrey M. Friedman
Clinical Napoleone Ferrara Discovery of VEGF as a major mediator of angiogenesis and the development of an effective anti-VEGF therapy for wet macular degeneration, a leading cause of blindness in the elderly.[32]
Special Achievement David Weatherall For 50 years of international statesmanship in biomedical science – exemplified by discoveries concerning genetic diseases of the blood and for leadership in improving clinical care for thousands of children with thalassemia throughout the developing world.[33]
2009 Basic John Gurdon Discoveries concerning nuclear reprogramming, the process that instructs specialized adult cells to form early stem cells – creating the potential to become any type of mature cell for experimental or therapeutic purposes.[34]
Shinya Yamanaka
Clinical Brian Druker The development of molecularly-targeted treatments for chronic myeloid leukemia, converting a fatal cancer into a manageable chronic condition.[35]
Nicholas Lydon
Charles Sawyers
Public Service Michael Bloomberg Employing sound science in political decision making; setting a world standard for the public's health as an impetus for government action; leading the way to reduce the scourge of tobacco use; and advancing public health through enlightened philanthropy.[36]
2008 Basic Victor Ambros Discoveries that revealed an unanticipated world of tiny RNAs that regulate gene function in plants and animals.[37]
David Baulcombe
Gary Ruvkun
Clinical Akira Endo The discovery of the statins – drugs with remarkable LDL-cholesterol-lowering properties that have revolutionized the prevention and treatment of coronary heart disease.[38]
Special Achievement Stanley Falkow A 51-year career as one of the great microbe hunters of all time – he discovered the molecular nature of antibiotic resistance, revolutionized the way we think about how pathogens cause disease, and mentored more than 100 students, many of whom are now distinguished leaders in the fields of microbiology and infectious diseases.[2]
2007 Basic Ralph Steinman The discovery of dendritic cells – the preeminent component of the immune system that initiates and regulates the body's response to foreign antigens.[39]
Clinical Alain Carpentier The development of prosthetic mitral and aortic valves, which have prolonged and enhanced the lives of millions of people with heart disease.[40]
Albert Starr
Public Service Anthony Fauci For his role as the principal architect of two major U.S. governmental programs, one aimed at AIDS and the other at biodefense.[41]
2006 Basic Elizabeth Blackburn The prediction and discovery of telomerase, a remarkable RNA-containing enzyme that synthesizes the ends of chromosomes, protecting them and maintaining the integrity of the genome[42]
Carol Greider
Jack Szostak
Clinical Aaron Beck The development of cognitive therapy, which has transformed the understanding and treatment of many psychiatric conditions, including depression, suicidal behavior, generalized anxiety, panic attacks, and eating disorders.[43]
Special Achievement Joseph Gall A distinguished 57-year-career as a founder of modern cell biology and the field of chromosome structure and function; bold experimentalist; inventor of in situ hybridization; and early champion of women in science.[44]
2005 Basic Ernest McCulloch Ingenious experiments that first identified a stem cell – the blood-forming stem cell – which set the stage for all current research on adult and embryonic stem cells.[45]
James Till
Clinical Alec John Jeffreys Development of two powerful technologies – Southern hybridization and DNA fingerprinting – that together revolutionized human genetics and forensic diagnostics.[46]
Edwin Mellor Southern
Public Service Nancy Brinker For creating one of the world's great foundations devoted to curing breast cancer and for dramatically increasing public awareness about this devastating disease.[47]
2004 Basic Pierre Chambon For the discovery of the superfamily of nuclear hormone receptors and elucidation of a unifying mechanism that regulates embryonic development and diverse metabolic pathways.[48]
Ronald M. Evans
Elwood V. Jensen
Clinical Charles Kelman For revolutionizing the surgical removal of cataracts, turning a 10-day hospital stay into an outpatient procedure, and dramatically reducing complications.[49]
Special Achievement Matthew Meselson For a lifetime career that combines penetrating discovery in molecular biology with creative leadership in the public policy of chemical and biological weapons.[50]
2003 Basic Robert G. Roeder Pioneering studies on eukaryotic RNA polymerases and the general transcriptional machinery, which opened gene expression in animal cells to biochemical analysis.[51]
Clinical Marc Feldmann Discovery of anti-TNF therapy as an effective treatment for rheumatoid arthritis and other autoimmune diseases.[52]
Ravinder N. Maini
Public Service Christopher Reeve Perceptive, sustained, and heroic advocacy for medical research in general, and victims of disability in particular.[53]
2002 Basic James E. Rothman Discoveries revealing the universal molecular machinery that orchestrates the budding and fusion of membrane vesicles – a process essential to organelle formation, nutrient uptake, and secretion of hormones and neurotransmitters.[54]
Randy W. Schekman
Clinical Willem J. Kolff Development of renal hemodialysis, which changed kidney failure from a fatal to a treatable disease, prolonging the useful lives of millions of patients.[55]
Belding H. Scribner
Special Achievement James E. Darnell Jr. For an exceptional career in biomedical science during which he opened two fields in biology – RNA processing and cytokine signaling – and fostered the development of many creative scientists.[56]
2001 Basic Mario R. Capecchi Development of a powerful technology for manipulating the mouse genome with exquisite precision, which allows the creation of animal models of human disease.[57]
Martin J. Evans
Oliver Smithies
Clinical Robert G. Edwards Development of in vitro fertilization, a technological advance that has revolutionized the treatment of human infertility.[58]
Public Service William H. Foege For courageous leadership in improving worldwide public health, and his prominent role in the eradication of smallpox.[59]
2000 Basic Aaron Ciechanover For the discovery and recognition of the broad significance of the ubiquitin system of regulated protein degradation, a fundamental process that influences vital cellular events, including the cell cycle, malignant transformation, and responses to inflammation and immunity.[60]
Avram Hershko
Alexander Varshavsky
Clinical Harvey J. Alter Discovery of the virus that causes hepatitis C and the development of screening methods that reduced the risk of blood transfusion-associated hepatitis in the U.S. from 30% in 1970 to virtually zero in 2000.[61]
Michael Houghton
Special Achievement Sydney Brenner For 50 years of brilliant creativity in biomedical science – exemplified by his legendary work on the genetic code; his daring introduction of the roundworm Caenorhabditis elegans as a system for tracing the birth and death of every cell in a living animal; his rational voice in the debate on recombinant DNA; and his trenchant wit.[62]

Historical awards

Awards no longer made include Special Public Health Awards, Special Awards, Group Awards, and Lasker Awards made by the International Society for the Rehabilitation of the Disabled, the National Committee Against Mental Illness, and Planned Parenthood - World Population.[5] Awards were also presented for medical journalism.[5]

Special Public Health awards

Special awards

Group awards

International Society for the Rehabilitation of the Disabled

National Committee Against Mental Illness

Planned Parenthood - World Population

See also

References

  1. ^ a b "The Lasker Awards Overview". Retrieved 2013-11-26.
  2. ^ a b The Lasker Foundation – 2008 Special Achievement Award
  3. ^ . Archived from the original on 2015-05-31. Retrieved 2015-06-07.
  4. ^ "Albert and Mary Lasker Foundation - Albert Lasker Awards Archives (1944-)". National Library of Medicine.
  5. ^ a b c "Historical Archive: Awards No Longer Given by the Foundation". Lasker Foundation. Retrieved 2019-10-17.
  6. ^ The Lasker Foundation – 2022 Basic Medical Research Award
  7. ^ The Lasker Foundation – 2022 Clinical Medical Research Award
  8. ^ The Lasker Foundation – 2022 Special Achievement
  9. ^ The Lasker Foundation – 2021 Basic Medical Research Award
  10. ^ The Lasker Foundation – 2021 Clinical Medical Research Award
  11. ^ The Lasker Foundation – 2021 Special Achievement
  12. ^ - 2019 Basic Medical Research Award
  13. ^ - 2019 Clinical Medical Research Award
  14. ^ The Lasker Foundation - 2019 Public Service Award
  15. ^ The Lasker Foundation – 2017 Basic Medical Research Award
  16. ^ The Lasker Foundation – 2016 Basic Medical Research Award
  17. ^ The Lasker Foundation – 2016 Clinical Medical Research Award
  18. ^ The Lasker Foundation – 2016 Special Achievement
  19. ^ The Lasker Foundation – 2015 Basic Medical Research Award
  20. ^ The Lasker Foundation – 2015 Clinical Medical Research Award
  21. ^ The Lasker Foundation – 2015 Public Service Award
  22. ^ The Lasker Foundation – 2013 Basic Medical Research Award
  23. ^ The Lasker Foundation – 2013 Clinical Medical Research Award
  24. ^ The Lasker Foundation – 2013 Public Service
  25. ^ The Lasker Foundation – 2012 Basic Medical Research Award 2012-09-23 at the Wayback Machine
  26. ^ The Lasker Foundation – 2012 Clinical Medical Research Award
  27. ^ The Lasker Foundation – 2012 Special Achievement 2012-09-29 at the Wayback Machine
  28. ^ The Lasker Foundation – 2011 Basic Medical Research Award 2011-09-26 at the Wayback Machine
  29. ^ The Lasker Foundation – 2011 Clinical Medical Research Award
  30. ^ The Lasker Foundation – 2011 Public Service Award 2011-09-27 at the Wayback Machine
  31. ^ The Lasker Foundation – 2010 Basic Medical Research Award 2010-10-08 at the Wayback Machine
  32. ^ The Lasker Foundation – 2010 Clinical Medical Research Award 2011-03-22 at the Wayback Machine
  33. ^ The Lasker Foundation – 2010 Special Achievement Award 2011-03-22 at the Wayback Machine
  34. ^ The Lasker Foundation – 2009 Basic Medical Research Award 2009-09-25 at the Wayback Machine
  35. ^ The Lasker Foundation – 2009 Clinical Medical Research Award 2009-09-22 at the Wayback Machine
  36. ^ The Lasker Foundation – 2009 Public Service Award 2009-09-25 at the Wayback Machine
  37. ^ The Lasker Foundation – 2008 Basic Medical Research Award 2008-09-19 at the Wayback Machine
  38. ^ The Lasker Foundation – 2008 Clinical Medical Research Award 2008-09-19 at the Wayback Machine
  39. ^ The Lasker Foundation – 2007 Basic Medical Research Award
  40. ^ The Lasker Foundation – 2007 Clinical Medical Research Award 2008-09-19 at the Wayback Machine
  41. ^ The Lasker Foundation – 2007 Public Service Award 2008-09-19 at the Wayback Machine
  42. ^ The Lasker Foundation – 2006 Basic Medical Research Award
  43. ^ The Lasker Foundation – 2006 Clinical Medical Research Award 2008-09-19 at the Wayback Machine
  44. ^ The Lasker Foundation – 2006 Special Achievement Award 2008-09-19 at the Wayback Machine
  45. ^ The Lasker Foundation – 2005 Basic Medical Research Award 2010-07-16 at the Wayback Machine
  46. ^ The Lasker Foundation – 2005 Clinical Medical Research Award 2010-07-16 at the Wayback Machine
  47. ^ The Lasker Foundation – 2005 Public Service Award 2008-09-19 at the Wayback Machine
  48. ^ The Lasker Foundation – 2004 Basic Medical Research Award
  49. ^ The Lasker Foundation – 2004 Clinical Medical Research Award 2010-07-16 at the Wayback Machine
  50. ^ The Lasker Foundation – 2004 Special Achievement Award 2008-09-19 at the Wayback Machine
  51. ^ The Lasker Foundation – 2003 Basic Medical Research Award 2010-07-16 at the Wayback Machine
  52. ^ The Lasker Foundation – 2003 Clinical Medical Research Award 2010-07-16 at the Wayback Machine
  53. ^ The Lasker Foundation – 2003 Public Service Award 2008-09-19 at the Wayback Machine
  54. ^ The Lasker Foundation – 2002 Basic Medical Research Award 2010-07-16 at the Wayback Machine
  55. ^ The Lasker Foundation – 2002 Clinical Medical Research Award 2010-07-16 at the Wayback Machine
  56. ^ The Lasker Foundation – 2002 Special Achievement Award 2010-07-16 at the Wayback Machine
  57. ^ The Lasker Foundation – 2001 Basic Medical Research Award 2010-07-16 at the Wayback Machine
  58. ^ The Lasker Foundation – 2001 Clinical Medical Research Award 2010-10-09 at the Wayback Machine
  59. ^ The Lasker Foundation – 2001 Public Service Award 2010-07-16 at the Wayback Machine
  60. ^ The Lasker Foundation – 2000 Basic Medical Research Award 2015-03-30 at the Wayback Machine
  61. ^ The Lasker Foundation – 2000 Clinical Medical Research Award 2012-05-18 at the Wayback Machine
  62. ^ The Lasker Foundation – 2000 Special Achievement Award
  63. ^ "The Albert Lasker Awards for 1960". American Journal of Public Health and the Nation's Health. 50 (12): 1948. 1960. doi:10.2105/AJPH.50.12.1946. PMC 1373507. PMID 18017803.

External links

  • The Lasker Foundation - Official site
  • Albert and Mary Lasker Foundation - Albert Lasker Awards Archives (1944-)—National Library of Medicine finding aid

lasker, award, have, been, awarded, annually, since, 1945, living, persons, have, made, major, contributions, medical, science, have, performed, public, service, behalf, medicine, they, administered, lasker, foundation, which, founded, albert, lasker, wife, ma. The Lasker Awards have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine They are administered by the Lasker Foundation which was founded by Albert Lasker and his wife Mary Woodard Lasker later a medical research activist The awards are sometimes referred to as America s Nobels Lasker AwardPresident Lyndon Johnson accepting the special Albert Lasker Award for Leadership in HealthAwarded forMajor contributions to medical scienceSponsored byLasker FoundationDate1945Reward s 250 000HighlightsBasic 2019 Max Dale Cooper Jacques MillerClinical 2019 H Michael Shepard Dennis J Slamon Axel UllrichPublic Service 2019 GAVIWebsitelaskerfoundation wbr orgThe Lasker Awards have gained a reputation for identifying future winners of the Nobel Prize Eighty six Lasker laureates have received the Nobel Prize including 32 in the last two decades 1 2 Claire Pomeroy is the current president of the Lasker Foundation Contents 1 Award 2 Recent awards 3 Historical awards 3 1 Special Public Health awards 3 2 Special awards 3 3 Group awards 3 4 International Society for the Rehabilitation of the Disabled 3 5 National Committee Against Mental Illness 3 6 Planned Parenthood World Population 4 See also 5 References 6 External linksAward EditThe award is given in four branches of medical science 1 Albert Lasker Basic Medical Research Award Lasker DeBakey Clinical Medical Research Award Lasker Bloomberg Public Service Award Renamed in 2011 from Mary Woodard Lasker Public Service Award Renamed in 2000 from Albert Lasker Public Service Award Lasker Koshland Special Achievement Award in Medical Science 1994 optional The awards carry an honorarium of 250 000 for each category 3 A collection of papers from the Albert and Mary Lasker Foundation were donated to the National Library of Medicine by Mrs Albert D Lasker in April 1985 4 In addition to the main awards there are historical awards that are no longer awarded 5 Recent awards EditRecent winners include the following Year Award Laureate s Reason2022 Basic Richard O Hynes For discoveries concerning the integrins key mediators of cell matrix and cell cell adhesion in physiology and disease 6 Erkki RuoslahtiTimothy A SpringerClinical Yuk Ming Dennis Lo For the discovery of fetal DNA in maternal blood leading to noninvasive prenatal testing for Down syndrome 7 Public Service Lauren Gardner For creating the Covid 19 Dashboard which set a new standard for disseminating authoritative public health data in real time 8 2021 Basic Karl Deisseroth For the discovery of light sensitive microbial proteins that can activate or silence individual brain cells and for their use in developing optogenetics a revolutionary technique for neuroscience 9 Peter HegemannDieter OesterheltClinical Katalin Kariko For the discovery of a new therapeutic technology based on the modification of messenger RNA enabling rapid development of highly effective Covid 19 vaccines 10 Drew WeissmanSpecial Achievement David Baltimore As one of the premier biomedical scientists of the last five decades he is renowned for the breadth and beauty of his discoveries in virology immunology and cancer for his academic leadership for his mentorship of prominent scientists and for his influence as a public advocate for science 11 2019 Basic Max Dale Cooper For their discovery of the two distinct classes of lymphocytes B and T cells a monumental achievement that provided the organizing principle of the adaptive immune system and launched the course of modern immunology 12 Jacques MillerClinical H Michael Shepard For their invention of Herceptin the first monoclonal antibody that blocks a cancer causing protein and for its development as a life saving therapy for women with breast cancer 13 Dennis J SlamonAxel UllrichPublic Service GAVI vaccination alliance For providing sustained access to childhood vaccines around the globe saving millions of lives and for highlighting the power of immunization to prevent disease 14 2018 Basic C David Allis For discoveries elucidating how gene expression is influenced by chemical modification of histones the proteins that package DNA within chromosomes Michael GrunsteinClinical John B Glen For the discovery and development of propofol a chemical whose rapid action and freedom from residual effects have made it the most widely used agent for induction of anesthesia in patients throughout the world Special Achievement Joan Argetsinger Steitz For four decades of leadership in biomedical science exemplified by pioneering discoveries in RNA biology generous mentorship of budding scientists and vigorous and passionate support of women in science 2017 Basic Michael N Hall For discoveries concerning the nutrient activated TOR proteins and their central role in the metabolic control of cell growth 15 Clinical Douglas R Lowy For technological advances that enabled development of HPV vaccines for prevention of cervical cancer and other tumors caused by human papillomaviruses John T Schiller de Public Service Planned Parenthood For providing essential health services and reproductive care to millions of women for more than a century 2016 Basic William G Kaelin Jr For the discovery of the pathway by which cells from humans and most animals sense and adapt to changes in oxygen availability a process essential for survival 16 Peter J RatcliffeGregg L SemenzaClinical Ralf F W Bartenschlager For development of a system to study the replication of the virus that causes hepatitis C and for use of this system to revolutionize the treatment of this chronic often lethal disease 17 Charles M RiceMichael J SofiaSpecial Achievement Bruce M Alberts For fundamental discoveries in DNA replication and protein biochemistry for visionary leadership in directing national and international scientific organizations to better people s lives and for passionate dedication to improving education in science and mathematics 18 2015 Basic Stephen J Elledge For discoveries concerning the DNA damage response a fundamental mechanism that protects the genomes of all living organisms 19 Evelyn M WitkinClinical James P Allison For the discovery and development of a monoclonal antibody therapy that unleashes the immune system to combat cancer 20 Public Service Medecins Sans Frontieres For bold leadership in responding to the recent Ebola outbreak in Africa and for sustained and effective frontline responses to health emergencies 21 2014 Basic Kazutoshi Mori For discoveries concerning the unfolded protein response an intracellular quality control system that detects harmful misfolded proteins in the endoplasmic reticulum and signals the nucleus to carry out corrective measures Peter WalterClinical Alim Louis Benabid For the development of deep brain stimulation of the subthalamic nucleus a surgical technique that reduces tremors and restores motor function in patients with advanced Parkinson s disease Mahlon R DeLongSpecial Achievement Mary Claire King For bold imaginative and diverse contributions to medical science and human rights she discovered the BRCA1 gene locus that causes hereditary breast cancer and deployed DNA strategies that reunite missing persons or their remains with their families 2013 Basic Richard H Scheller For discoveries concerning the molecular machinery and regulatory mechanism that underlie the rapid release of neurotransmitters 22 Thomas C SudhofClinical Graeme M Clark For the development of the modern cochlear implant a device that bestows hearing to individuals with profound deafness 23 Ingeborg HochmairBlake S WilsonPublic Service Bill Gates For leading a historic transformation in the way we view the globe s most pressing health concerns and improving the lives of millions of the world s most vulnerable 24 Melinda Gates2012 Basic Michael Sheetz For discoveries concerning cytoskeletal motor proteins machines that move cargoes within cells contract muscles and enable cell movements 25 James SpudichRonald ValeClinical Roy Calne For the development of liver transplantation which has restored normal life to thousands of patients with end stage liver disease 26 Thomas StarzlSpecial Achievement Donald D Brown For exceptional leadership and citizenship in biomedical science exemplified by fundamental discoveries concerning the nature of genes by selfless commitment to young scientists and by disseminating revolutionary technologies to the scientific community 27 Tom Maniatis2011 Basic Franz Ulrich Hartl For discoveries concerning the cell s protein folding machinery exemplified by cage like structures that convert newly made proteins into their biologically active forms 28 Arthur L HorwichClinical Tu Youyou For the discovery of artemisinin a drug therapy for malaria that has saved millions of lives across the globe especially in the developing world 29 Public Service National Institutes of Health Clinical Center For serving since its inception as a model research hospital providing innovative therapy and high quality patient care treating rare and severe diseases and producing outstanding physician scientists whose collective work has set a standard of excellence in biomedical research 30 2010 Basic Douglas L Coleman Discovery of leptin a hormone that regulates appetite and body weight a breakthrough that opened obesity research to molecular exploration 31 Jeffrey M FriedmanClinical Napoleone Ferrara Discovery of VEGF as a major mediator of angiogenesis and the development of an effective anti VEGF therapy for wet macular degeneration a leading cause of blindness in the elderly 32 Special Achievement David Weatherall For 50 years of international statesmanship in biomedical science exemplified by discoveries concerning genetic diseases of the blood and for leadership in improving clinical care for thousands of children with thalassemia throughout the developing world 33 2009 Basic John Gurdon Discoveries concerning nuclear reprogramming the process that instructs specialized adult cells to form early stem cells creating the potential to become any type of mature cell for experimental or therapeutic purposes 34 Shinya YamanakaClinical Brian Druker The development of molecularly targeted treatments for chronic myeloid leukemia converting a fatal cancer into a manageable chronic condition 35 Nicholas LydonCharles SawyersPublic Service Michael Bloomberg Employing sound science in political decision making setting a world standard for the public s health as an impetus for government action leading the way to reduce the scourge of tobacco use and advancing public health through enlightened philanthropy 36 2008 Basic Victor Ambros Discoveries that revealed an unanticipated world of tiny RNAs that regulate gene function in plants and animals 37 David BaulcombeGary RuvkunClinical Akira Endo The discovery of the statins drugs with remarkable LDL cholesterol lowering properties that have revolutionized the prevention and treatment of coronary heart disease 38 Special Achievement Stanley Falkow A 51 year career as one of the great microbe hunters of all time he discovered the molecular nature of antibiotic resistance revolutionized the way we think about how pathogens cause disease and mentored more than 100 students many of whom are now distinguished leaders in the fields of microbiology and infectious diseases 2 2007 Basic Ralph Steinman The discovery of dendritic cells the preeminent component of the immune system that initiates and regulates the body s response to foreign antigens 39 Clinical Alain Carpentier The development of prosthetic mitral and aortic valves which have prolonged and enhanced the lives of millions of people with heart disease 40 Albert StarrPublic Service Anthony Fauci For his role as the principal architect of two major U S governmental programs one aimed at AIDS and the other at biodefense 41 2006 Basic Elizabeth Blackburn The prediction and discovery of telomerase a remarkable RNA containing enzyme that synthesizes the ends of chromosomes protecting them and maintaining the integrity of the genome 42 Carol GreiderJack SzostakClinical Aaron Beck The development of cognitive therapy which has transformed the understanding and treatment of many psychiatric conditions including depression suicidal behavior generalized anxiety panic attacks and eating disorders 43 Special Achievement Joseph Gall A distinguished 57 year career as a founder of modern cell biology and the field of chromosome structure and function bold experimentalist inventor of in situ hybridization and early champion of women in science 44 2005 Basic Ernest McCulloch Ingenious experiments that first identified a stem cell the blood forming stem cell which set the stage for all current research on adult and embryonic stem cells 45 James TillClinical Alec John Jeffreys Development of two powerful technologies Southern hybridization and DNA fingerprinting that together revolutionized human genetics and forensic diagnostics 46 Edwin Mellor SouthernPublic Service Nancy Brinker For creating one of the world s great foundations devoted to curing breast cancer and for dramatically increasing public awareness about this devastating disease 47 2004 Basic Pierre Chambon For the discovery of the superfamily of nuclear hormone receptors and elucidation of a unifying mechanism that regulates embryonic development and diverse metabolic pathways 48 Ronald M EvansElwood V JensenClinical Charles Kelman For revolutionizing the surgical removal of cataracts turning a 10 day hospital stay into an outpatient procedure and dramatically reducing complications 49 Special Achievement Matthew Meselson For a lifetime career that combines penetrating discovery in molecular biology with creative leadership in the public policy of chemical and biological weapons 50 2003 Basic Robert G Roeder Pioneering studies on eukaryotic RNA polymerases and the general transcriptional machinery which opened gene expression in animal cells to biochemical analysis 51 Clinical Marc Feldmann Discovery of anti TNF therapy as an effective treatment for rheumatoid arthritis and other autoimmune diseases 52 Ravinder N MainiPublic Service Christopher Reeve Perceptive sustained and heroic advocacy for medical research in general and victims of disability in particular 53 2002 Basic James E Rothman Discoveries revealing the universal molecular machinery that orchestrates the budding and fusion of membrane vesicles a process essential to organelle formation nutrient uptake and secretion of hormones and neurotransmitters 54 Randy W SchekmanClinical Willem J Kolff Development of renal hemodialysis which changed kidney failure from a fatal to a treatable disease prolonging the useful lives of millions of patients 55 Belding H ScribnerSpecial Achievement James E Darnell Jr For an exceptional career in biomedical science during which he opened two fields in biology RNA processing and cytokine signaling and fostered the development of many creative scientists 56 2001 Basic Mario R Capecchi Development of a powerful technology for manipulating the mouse genome with exquisite precision which allows the creation of animal models of human disease 57 Martin J EvansOliver SmithiesClinical Robert G Edwards Development of in vitro fertilization a technological advance that has revolutionized the treatment of human infertility 58 Public Service William H Foege For courageous leadership in improving worldwide public health and his prominent role in the eradication of smallpox 59 2000 Basic Aaron Ciechanover For the discovery and recognition of the broad significance of the ubiquitin system of regulated protein degradation a fundamental process that influences vital cellular events including the cell cycle malignant transformation and responses to inflammation and immunity 60 Avram HershkoAlexander VarshavskyClinical Harvey J Alter Discovery of the virus that causes hepatitis C and the development of screening methods that reduced the risk of blood transfusion associated hepatitis in the U S from 30 in 1970 to virtually zero in 2000 61 Michael HoughtonSpecial Achievement Sydney Brenner For 50 years of brilliant creativity in biomedical science exemplified by his legendary work on the genetic code his daring introduction of the roundworm Caenorhabditis elegans as a system for tracing the birth and death of every cell in a living animal his rational voice in the debate on recombinant DNA and his trenchant wit 62 Historical awards EditAwards no longer made include Special Public Health Awards Special Awards Group Awards and Lasker Awards made by the International Society for the Rehabilitation of the Disabled the National Committee Against Mental Illness and Planned Parenthood World Population 5 Awards were also presented for medical journalism 5 Special Public Health awards Edit 1975 Merck Sharp and Dohme Research Laboratories Karl H Beyer de Jr James M Sprague John E Baer Frederick C Novello 1980 National Heart Lung and Blood Institute 1984 Dorothy T Krieger Kevin McLaughlin Jr 1987 Centennial Salute to the National Institutes of HealthSpecial awards Edit 1947 Thomas Parran Jr 1949 Haven Emerson 1952 Charles Edward Amory Winslow 1956 Alan Gregg 1959 J Lister Hill and John E FogartyGroup awards Edit 1946 National Institutes of Health National Regional Research Laboratory of the US Department of Agriculture Board for the Coordination of Malarial Studies Bureau of Entomology and Plant Quarantine of the US Department of Agriculture Army Epidemiological Board 1947 British Ministry of Health and Ministry of Food United States Committee on Joint Causes of Death 1948 Veterans Administration s Department of Medicine and Surgery 1949 American Academy of Pediatrics Life Insurance Medical Research Fund 1950 International Health Division of The Rockefeller Foundation 1951 Health Insurance Plan of Greater New York Alcoholics Anonymous 1953 Division of Research Grants of the National Institutes of Health University Laboratory of Physical Chemistry Related to Medicine at Harvard University 1954 Streptococcal Disease Laboratory Armed Forces Epidemiological Board Francis E Warren Air Force Base Charles H Rammelkamp Jr Director 1956 Food and Drug Administration Medical Care Program Welfare and Retirement Fund of the United Mine Workers of America 1960 Crippled Children s Program of the Children s Bureau Chronic Disease Program of the California State Department of Public Health Lester Breslow 63 International Society for the Rehabilitation of the Disabled Edit 1954 Henry H Kessler Juan Farill Viscount Nuffield 1957 Howard A Rusk Fabian W G Langenskiold World Veterans Federation 1960 Mary E Switzer Gudmund Harlem Paul W Brand 1963 Renato de Costa Bomfim Kurt Jansson Leonard W Mayo 1966 Poul Stochholm Wiktor Dega Eugene J Taylor 1969 Gustav Gringas Mr and Mrs Raden Soeharso Andre Trannoy International Labour Organization 1972 James F Garrett Kamala V Nimbkar Jean RegniersNational Committee Against Mental Illness Edit 1944 William C Menninger 1945 G Brock Chisholm John Rawlings Rees 1946 W Horsley Gantt Jules H Masserman Walter Lerch Douglass Rice Sharpe Lawrence K Frank 1947 Catherine MacKenzie 1948 C Anderson Aldrich Mike Gorman Al Ostrow 1949 Mildred C Scoville Albert DeutschPlanned Parenthood World Population Edit 1945 John McLeod Felix J Underwood 1946 Robert Latou Dickinson Irl Cephas Riggin 1947 Alan F Guttmacher Abraham Stone 1948 John Rock Richard N Pierson 1949 George M Cooper Carl G Hartman 1950 Margaret Sanger Bessie L Moses 1951 Guy Irving Burch William Vogt 1952 John William Roy Norton Herbert Thoms Eleanor Bellows Pillsbury 1953 Harry Emerson Fosdick Elise Ottesen Jensen 1954 Dhanvanthi Rama Rau M C Chang Howard C Taylor 1955 Warren O Nelson Robert Carter Cook 1958 Harrison S Brown 1959 Julian Huxley 1960 Gregory Pincus 1961 John D Rockefeller III 1964 Cass Canfield 1965 C Lee Buxton Estelle T GriswoldSee also EditList of medicine awardsReferences Edit a b The Lasker Awards Overview Retrieved 2013 11 26 a b The Lasker Foundation 2008 Special Achievement Award The Lasker Awards Media page Archived from the original on 2015 05 31 Retrieved 2015 06 07 Albert and Mary Lasker Foundation Albert Lasker Awards Archives 1944 National Library of Medicine a b c Historical Archive Awards No Longer Given by the Foundation Lasker Foundation Retrieved 2019 10 17 The Lasker Foundation 2022 Basic Medical Research Award The Lasker Foundation 2022 Clinical Medical Research Award The Lasker Foundation 2022 Special Achievement The Lasker Foundation 2021 Basic Medical Research Award The Lasker Foundation 2021 Clinical Medical Research Award The Lasker Foundation 2021 Special Achievement 2019 Basic Medical Research Award 2019 Clinical Medical Research Award The Lasker Foundation 2019 Public Service Award The Lasker Foundation 2017 Basic Medical Research Award The Lasker Foundation 2016 Basic Medical Research Award The Lasker Foundation 2016 Clinical Medical Research Award The Lasker Foundation 2016 Special Achievement The Lasker Foundation 2015 Basic Medical Research Award The Lasker Foundation 2015 Clinical Medical Research Award The Lasker Foundation 2015 Public Service Award The Lasker Foundation 2013 Basic Medical Research Award The Lasker Foundation 2013 Clinical Medical Research Award The Lasker Foundation 2013 Public Service The Lasker Foundation 2012 Basic Medical Research Award Archived 2012 09 23 at the Wayback Machine The Lasker Foundation 2012 Clinical Medical Research Award The Lasker Foundation 2012 Special Achievement Archived 2012 09 29 at the Wayback Machine The Lasker Foundation 2011 Basic Medical Research Award Archived 2011 09 26 at the Wayback Machine The Lasker Foundation 2011 Clinical Medical Research Award The Lasker Foundation 2011 Public Service Award Archived 2011 09 27 at the Wayback Machine The Lasker Foundation 2010 Basic Medical Research Award Archived 2010 10 08 at the Wayback Machine The Lasker Foundation 2010 Clinical Medical Research Award Archived 2011 03 22 at the Wayback Machine The Lasker Foundation 2010 Special Achievement Award Archived 2011 03 22 at the Wayback Machine The Lasker Foundation 2009 Basic Medical Research Award Archived 2009 09 25 at the Wayback Machine The Lasker Foundation 2009 Clinical Medical Research Award Archived 2009 09 22 at the Wayback Machine The Lasker Foundation 2009 Public Service Award Archived 2009 09 25 at the Wayback Machine The Lasker Foundation 2008 Basic Medical Research Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2008 Clinical Medical Research Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2007 Basic Medical Research Award The Lasker Foundation 2007 Clinical Medical Research Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2007 Public Service Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2006 Basic Medical Research Award The Lasker Foundation 2006 Clinical Medical Research Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2006 Special Achievement Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2005 Basic Medical Research Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2005 Clinical Medical Research Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2005 Public Service Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2004 Basic Medical Research Award The Lasker Foundation 2004 Clinical Medical Research Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2004 Special Achievement Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2003 Basic Medical Research Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2003 Clinical Medical Research Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2003 Public Service Award Archived 2008 09 19 at the Wayback Machine The Lasker Foundation 2002 Basic Medical Research Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2002 Clinical Medical Research Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2002 Special Achievement Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2001 Basic Medical Research Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2001 Clinical Medical Research Award Archived 2010 10 09 at the Wayback Machine The Lasker Foundation 2001 Public Service Award Archived 2010 07 16 at the Wayback Machine The Lasker Foundation 2000 Basic Medical Research Award Archived 2015 03 30 at the Wayback Machine The Lasker Foundation 2000 Clinical Medical Research Award Archived 2012 05 18 at the Wayback Machine The Lasker Foundation 2000 Special Achievement Award The Albert Lasker Awards for 1960 American Journal of Public Health and the Nation s Health 50 12 1948 1960 doi 10 2105 AJPH 50 12 1946 PMC 1373507 PMID 18017803 External links EditThe Lasker Foundation Official site Albert and Mary Lasker Foundation Albert Lasker Awards Archives 1944 National Library of Medicine finding aid Retrieved from https en wikipedia org w index php title Lasker Award amp oldid 1112917622, wikipedia, wiki, book, books, library,

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