Carl was the son of Carl Isidor Cori (1865, Brüx [Czech: Most], Bohemia, Austrian Empire–1954, Vienna), a zoologist, and Maria Cori (née Lippich; 1870, Graz–1922, Prague), a daughter of the Italian-Bohemian/Austrian physician Ferdinand Lippich [de; cs] (1838, Padua–1913, Prague).[16][17]
The Cori family came from the Papal State (later the Roman Republic, today's Central Italy) to the royal Bohemian crownland, (Monarchical Austria at the end of the 17th century). Carl Ferdinand's grandfather Eduard Cori (1812–1889)[18] was an administrative officer and beekeeper in Brüx, and his grandmother was Rosina Trinks (?–1909).[19] Carl Ferdinand's younger sister Margarete Cori (born 1905) was a lecturer in Prague and the wife of the Bohemian geneticist Felix Mainx (1900, Prague–1983, Vienna).[20]
He grew up in Trieste, where his father Carl Isidor was the director of the Marine Biological Station. In late 1914 the Cori family moved to Prague and Carl entered the medical school of Charles University in Prague. While studying there he met his future wife Gerty Theresa Radnitz. He was drafted into the Austro-Hungarian Army and served in the ski corps, and later was transferred to the sanitary corps, for which he set up a laboratory in Trieste. At the end of the war Carl completed his studies, graduating with Gerty in 1920. Carl and Gerty married that year and worked together in clinics in Vienna. Their only child, Tom, married Anne, a daughter of the American constitutional lawyer and anti-feminist Phyllis Schlafly.[21]
Career
Carl was invited to Graz to work with Otto Loewi to study the effect of the vagus nerve on the heart (Loewi would receive the Nobel Prize in Physiology or Medicine in 1936 for this work). While Carl was in Graz, Gerty remained in Vienna. A year later Carl was offered a position at the State Institute for the Study of Malignant Diseases (now Roswell Park Comprehensive Cancer Center) in Buffalo, New York and the Coris moved to Buffalo, New York. In 1928, they became naturalized citizens of the United States.
While at the Institute the Coris’ research focused on carbohydrate metabolism, leading to the definition of the Cori cycle in 1929. In 1931, Carl accepted a position at the Washington University School of Medicine in St. Louis, Missouri. Carl joined as professor of pharmacology and in 1942 was made professor of biochemistry. In St. Louis, the Coris continued their research on glycogen and glucose and began to describe glycogenolysis, identifying and synthesizing the important enzyme glycogen phosphorylase. For these discoveries, they received the Nobel Prize in Physiology or Medicine in 1947, making them the third ever married couple to win the Nobel Prize.
Gerty died in 1957 and Carl married Anne Fitzgerald-Jones (1909-2006) in 1960. He stayed on at Washington University until 1966, when he retired as chair of the biochemistry department. He was appointed visiting professor of Biological Chemistry at Harvard University while maintaining a laboratory space at the Massachusetts General Hospital, where he pursued research in genetics. From 1968 to 1983, he collaborated with noted geneticist Salomé Glüecksohn-Waelsch of the Albert Einstein College of Medicine in New York, until the 1980s when illness prevented him from continuing.[22] In 1976, Carl received the Laurea honoris causa in Medicine from the University of Trieste. Carl shares a star with Gerty on the St. Louis Walk of Fame.[23]
^Kornberg, A. (2001). "Remembering our teachers". The Journal of Biological Chemistry. 276 (1): 3–11. doi:10.1016/S0021-9258(18)44198-1. PMID 11134064.
^Cohn, M. (1992). "Carl Ferdinand Cori: December 5, 1896-October 19, 1984". Biographical Memoirs of the National Academy of Sciences. 61: 79–109. PMID 11616228.
^Houssay, B. A. (1956). "Carl F. And Gerty T. Cori". Biochimica et Biophysica Acta. 20 (1): 11–16. doi:10.1016/0006-3002(56)90255-4. PMID 13315342.
^Cech, P. (2001). "The Coris, a married couple native to Prague and Nobel laureates". Casopis Lekaru Ceskych. 140 (1): 26–30. PMID 11242981.
^Shampo, M. A.; Kyle, R. A. (2000). "Carl Cori—Nobel Laureate in Medicine or Physiology". Mayo Clinic Proceedings. 75 (12): 1274. doi:10.4065/75.12.1274. PMID 11126836.
^Raju, T. N. (1999). "The Nobel Chronicles. 1947: Carl Ferdinand Cori (1896-1984); Gerty Theresa Radnitz Cori (1896-1957); and Bernardo Alberto Houssay (1887-1971)". Lancet. 353 (9158): 1108. doi:10.1016/s0140-6736(05)76476-x. PMID 10199387. S2CID 54345835.
^Sulek, K. (1968). "Nobel prize for Carl Ferdinand Cori and Gerta Theresa Cori in 1947 for discovery of the course of catalytic metabolism of glycogen. Prize for Alberto Bernardo Houssay for discovery on the role of the hypophysis in carbohydrate metabolism". Wiadomosci Lekarskie. 21 (17): 1609–1610. PMID 4882480.
^"Carl and Gerti Cori and Carbohydrate Metabolism". American Chemical Society. Archived from the original on January 12, 2013. Retrieved June 6, 2012.
^Kenéz, J. (1977). "Liver glycogen and enzyme research (Carl Ferdinand CPORI)". Orvosi Hetilap. 118 (8): 463–465. PMID 320540.
^Cori, C. F. (1969). "The Call of Science". Annual Review of Biochemistry. 38: 1–20. doi:10.1146/annurev.bi.38.070169.000245. PMID 4896237.
^. www.wien.gv.at. Archived from the original on 2017-02-02.
^"Nobels All Around | National Review". National Review. 22 September 2012. Retrieved 13 March 2018.
^Ginsberg, Judah (September 21, 2004). . National Historic Chemical Landmark. American Chemical Society. Archived from the original on October 24, 2012. Retrieved August 28, 2012.
^St. Louis Walk of Fame. . stlouiswalkoffame.org. Archived from the original on 31 October 2012. Retrieved 25 April 2013.
^"Reply to a parliamentary question" (PDF) (in German). p. 73. Retrieved 28 December 2012.
^"Carl F. Cori". www.nasonline.org. Retrieved 2023-03-15.
^"APS Member History". search.amphilsoc.org. Retrieved 2023-03-15.
^"Carl Ferdinand Cori". American Academy of Arts & Sciences. Retrieved 2023-03-15.
^Colin G. Nichols named Carl F. Cori Professor 2016-01-07 at the Wayback Machine, Washington University in St. Louis, 2007-02-21
External links
Carl Cori on Nobelprize.org including the Nobel Lecture December 11, 1947 Polysaccharide Phosphorylase
March 24, 2023
carl, ferdinand, cori, formemrs, december, 1896, october, 1984, czech, american, biochemist, pharmacologist, born, prague, then, austria, hungary, czech, republic, together, with, wife, gerty, cori, argentine, physiologist, bernardo, houssay, received, nobel, . Carl Ferdinand Cori ForMemRS 1 December 5 1896 October 20 1984 was a Czech American biochemist and pharmacologist born in Prague 3 4 then in Austria Hungary now Czech Republic who together with his wife Gerty Cori and Argentine physiologist Bernardo Houssay received a Nobel Prize in 1947 for their discovery of how the glucose derivative glycogen animal starch is broken down and resynthesized in the body for use as a store and source of energy 5 6 7 8 9 In 2004 both Coris were designated a National Historic Chemical Landmark in recognition of their work that elucidated carbohydrate metabolism 10 11 12 13 14 15 Carl Ferdinand CoriBorn 1896 12 05 December 5 1896Prague Austro Hungarian EmpireDiedOctober 20 1984 1984 10 20 aged 87 Cambridge Massachusetts U S NationalityAustrian HungarianCitizenshipUnited StatesAlma materFirst Faculty of Medicine Charles University in PragueKnown forMetabolism of carbohydratesSpouse s Gerty Radnitz m 1920 died 1957 wbr Anne Fitzgerald Jones m 1960 wbr Children1AwardsAlbert Lasker Award for Basic Medical Research 1946 Nobel Prize in Physiology or Medicine 1947 Willard Gibbs Award 1948 ForMemRS 1950 1 Scientific careerFieldsBiochemistryInstitutionsWashington University in St LouisInfluencedArthur Kornberg 2 Websitenobelprize wbr org wbr medicine wbr laureates wbr 1947 wbr cori cf bio wbr htmlCarl Cori with his wife and fellow Nobelist Gerty Cori in 1947 Contents 1 Education and early life 2 Career 3 Awards and honors 4 References 5 External linksEducation and early life EditCarl was the son of Carl Isidor Cori 1865 Brux Czech Most Bohemia Austrian Empire 1954 Vienna a zoologist and Maria Cori nee Lippich 1870 Graz 1922 Prague a daughter of the Italian Bohemian Austrian physician Ferdinand Lippich de cs 1838 Padua 1913 Prague 16 17 The Cori family came from the Papal State later the Roman Republic today s Central Italy to the royal Bohemian crownland Monarchical Austria at the end of the 17th century Carl Ferdinand s grandfather Eduard Cori 1812 1889 18 was an administrative officer and beekeeper in Brux and his grandmother was Rosina Trinks 1909 19 Carl Ferdinand s younger sister Margarete Cori born 1905 was a lecturer in Prague and the wife of the Bohemian geneticist Felix Mainx 1900 Prague 1983 Vienna 20 He grew up in Trieste where his father Carl Isidor was the director of the Marine Biological Station In late 1914 the Cori family moved to Prague and Carl entered the medical school of Charles University in Prague While studying there he met his future wife Gerty Theresa Radnitz He was drafted into the Austro Hungarian Army and served in the ski corps and later was transferred to the sanitary corps for which he set up a laboratory in Trieste At the end of the war Carl completed his studies graduating with Gerty in 1920 Carl and Gerty married that year and worked together in clinics in Vienna Their only child Tom married Anne a daughter of the American constitutional lawyer and anti feminist Phyllis Schlafly 21 Career EditCarl was invited to Graz to work with Otto Loewi to study the effect of the vagus nerve on the heart Loewi would receive the Nobel Prize in Physiology or Medicine in 1936 for this work While Carl was in Graz Gerty remained in Vienna A year later Carl was offered a position at the State Institute for the Study of Malignant Diseases now Roswell Park Comprehensive Cancer Center in Buffalo New York and the Coris moved to Buffalo New York In 1928 they became naturalized citizens of the United States While at the Institute the Coris research focused on carbohydrate metabolism leading to the definition of the Cori cycle in 1929 In 1931 Carl accepted a position at the Washington University School of Medicine in St Louis Missouri Carl joined as professor of pharmacology and in 1942 was made professor of biochemistry In St Louis the Coris continued their research on glycogen and glucose and began to describe glycogenolysis identifying and synthesizing the important enzyme glycogen phosphorylase For these discoveries they received the Nobel Prize in Physiology or Medicine in 1947 making them the third ever married couple to win the Nobel Prize Gerty died in 1957 and Carl married Anne Fitzgerald Jones 1909 2006 in 1960 He stayed on at Washington University until 1966 when he retired as chair of the biochemistry department He was appointed visiting professor of Biological Chemistry at Harvard University while maintaining a laboratory space at the Massachusetts General Hospital where he pursued research in genetics From 1968 to 1983 he collaborated with noted geneticist Salome Gluecksohn Waelsch of the Albert Einstein College of Medicine in New York until the 1980s when illness prevented him from continuing 22 In 1976 Carl received the Laurea honoris causa in Medicine from the University of Trieste Carl shares a star with Gerty on the St Louis Walk of Fame 23 Awards and honors EditIn addition to winning the Nobel Prize Cori won the Albert Lasker Award for Basic Medical Research in 1946 and in 1959 the Austrian Decoration for Science and Art 24 Cori was elected a member of the United States National Academy of Sciences in 1940 25 a member of the American Philosophical Society in 1947 26 a member of the American Academy of Arts and Sciences 27 and a Foreign Member of the Royal Society ForMemRS in 1950 1 The Carl Cori Endowed Professorship at Washington University is named in his honor currently held by Colin Nichols 28 References Edit a b c Randle Philip 1986 Carl Ferdinand Cori 5 December 1896 20 October 1984 Biographical Memoirs of Fellows of the Royal Society 32 66 95 doi 10 1098 rsbm 1986 0003 JSTOR 770108 PMID 11621260 Kornberg A 2001 Remembering our teachers The Journal of Biological Chemistry 276 1 3 11 doi 10 1016 S0021 9258 18 44198 1 PMID 11134064 Cohn M 1992 Carl Ferdinand Cori December 5 1896 October 19 1984 Biographical Memoirs of the National Academy of Sciences 61 79 109 PMID 11616228 Houssay B A 1956 Carl F And Gerty T Cori Biochimica et Biophysica Acta 20 1 11 16 doi 10 1016 0006 3002 56 90255 4 PMID 13315342 Cech P 2008 Nobel Prize laureates Casopis Lekaru Ceskych 147 7 410 412 PMID 18678102 Cech P 2001 The Coris a married couple native to Prague and Nobel laureates Casopis Lekaru Ceskych 140 1 26 30 PMID 11242981 Shampo M A Kyle R A 2000 Carl Cori Nobel Laureate in Medicine or Physiology Mayo Clinic Proceedings 75 12 1274 doi 10 4065 75 12 1274 PMID 11126836 Raju T N 1999 The Nobel Chronicles 1947 Carl Ferdinand Cori 1896 1984 Gerty Theresa Radnitz Cori 1896 1957 and Bernardo Alberto Houssay 1887 1971 Lancet 353 9158 1108 doi 10 1016 s0140 6736 05 76476 x PMID 10199387 S2CID 54345835 Sulek K 1968 Nobel prize for Carl Ferdinand Cori and Gerta Theresa Cori in 1947 for discovery of the course of catalytic metabolism of glycogen Prize for Alberto Bernardo Houssay for discovery on the role of the hypophysis in carbohydrate metabolism Wiadomosci Lekarskie 21 17 1609 1610 PMID 4882480 Carl and Gerti Cori and Carbohydrate Metabolism American Chemical Society Archived from the original on January 12 2013 Retrieved June 6 2012 Kenez J 1977 Liver glycogen and enzyme research Carl Ferdinand CPORI Orvosi Hetilap 118 8 463 465 PMID 320540 Cori C F 1969 The Call of Science Annual Review of Biochemistry 38 1 20 doi 10 1146 annurev bi 38 070169 000245 PMID 4896237 Carl Ferdinand Cori Biographical Memoirs of the National Academy of Sciences Ihde A J Cori Carl Ferdinand and Gerty Theresa Radnitz Cori American National Biography Online Feb 2000 Carl and Gerti Cori and Carbohydrate Metabolism Archived 2013 01 12 at archive today from American Chemical Society National Historic Chemical Landmarks Dolezal Helmut Cori Carl Isidor in Neue Deutsche Biographie 3 1957 p 360 1 2 3 4 5 commons File Anonym Franz Eduard Cori jpg Cori Carl Deutsche Biographie Felix Mainx Wien Geschichte Wiki www wien gv at Archived from the original on 2017 02 02 Nobels All Around National Review National Review 22 September 2012 Retrieved 13 March 2018 Ginsberg Judah September 21 2004 Carl and Gerty Cori and Carbohydrate Metabolism National Historic Chemical Landmark American Chemical Society Archived from the original on October 24 2012 Retrieved August 28 2012 St Louis Walk of Fame St Louis Walk of Fame Inductees stlouiswalkoffame org Archived from the original on 31 October 2012 Retrieved 25 April 2013 Reply to a parliamentary question PDF in German p 73 Retrieved 28 December 2012 Carl F Cori www nasonline org Retrieved 2023 03 15 APS Member History search amphilsoc org Retrieved 2023 03 15 Carl Ferdinand Cori American Academy of Arts amp Sciences Retrieved 2023 03 15 Colin G Nichols named Carl F Cori Professor Archived 2016 01 07 at the Wayback Machine Washington University in St Louis 2007 02 21External links EditCarl Cori on Nobelprize org including the Nobel Lecture December 11 1947 Polysaccharide Phosphorylase Retrieved from https en wikipedia org w index php title Carl Ferdinand Cori amp oldid 1144785277, wikipedia, wiki, book, books, library,
