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Carolyn Bertozzi

Carolyn Ruth Bertozzi (born October 10, 1966) is an American chemist and Nobel laureate, known for her wide-ranging work spanning both chemistry and biology. She coined the term "bioorthogonal chemistry"[2] for chemical reactions compatible with living systems. Her recent efforts include synthesis of chemical tools to study cell surface sugars called glycans and how they affect diseases such as cancer, inflammation, and viral infections like COVID-19.[3] At Stanford University, she holds the Anne T. and Robert M. Bass Professorship in the School of Humanities and Sciences.[4] Bertozzi is also an Investigator at the Howard Hughes Medical Institute (HHMI)[5] and is the former director of the Molecular Foundry, a nanoscience research center at Lawrence Berkeley National Laboratory.[6]

Carolyn Bertozzi
Bertozzi in 2022
Born
Carolyn Ruth Bertozzi

(1966-10-10) October 10, 1966 (age 57)
Boston, Massachusetts, U.S.
Education
Known forBioorthogonal chemistry
RelativesAndrea Bertozzi (sister)
Awards
Scientific career
FieldsChemistry
Institutions
ThesisSynthesis and biological activity of carbon-linked glycosides (1993)
Doctoral advisorMark D. Bednarski
Doctoral students
External videos
"What the sugar coating on your cells is trying to tell you", TEDx Stanford
"Carolyn R. Bertozzi Wins 2022 AAAS Lifetime Mentor Award", AAAS, 10 February 2022

She received the MacArthur "genius" award at age 33.[7] In 2010, she was the first woman to receive the prestigious Lemelson–MIT Prize faculty award. She is a member of the National Academy of Sciences (2005), the Institute of Medicine (2011), and the National Academy of Inventors (2013). In 2014, it was announced that Bertozzi would lead ACS Central Science, the American Chemical Society's first peer-reviewed open access journal, which offers all content free to the public.[8] Since 2021 she has been a member of the Accademia dei Lincei.[9] As an open lesbian in academia and science, Bertozzi has been a role model for students and colleagues.[10][11]

Bertozzi was awarded the 2022 Nobel Prize in Chemistry, jointly with Morten P. Meldal and Karl Barry Sharpless, "for the development of click chemistry and bioorthogonal chemistry".[12]

Education edit

Carolyn Bertozzi received her B.A. summa cum laude in chemistry from Harvard University, where she worked with Professor Joe Grabowski on the design and construction of a photoacoustic calorimeter.[13] Grabowski was impressed with her work and required Bertozzi to write a thesis on this project, which was submitted and Bertozzi won the Thomas T. Hoopes Undergraduate Thesis Prize with a large prize money.[14] While an undergraduate, she played in several bands, notably Bored of Education with future Rage Against the Machine guitarist Tom Morello.[15][16] After graduating from Harvard in 1988, she worked at Bell Labs with Chris Chidsey.[17]

Bertozzi completed her Ph.D. in chemistry at University of California, Berkeley in 1993 with Mark Bednarski, working on the chemical synthesis of oligosaccharide analogs.[18][19] While at Berkeley, she discovered that viruses can bind to sugars in the body.[20] The discovery led to her field of research, glycobiology. During Bertozzi's third year of graduate school, Bednarski was diagnosed with colon cancer, which resulted in him taking a leave of absence and changing his career path by enrolling in medical school. This left Bertozzi and the rest of the lab to complete their Ph.D. work with no direct supervision.[21][22]

Career and research edit

After graduating from Berkeley with a Ph.D., Bertozzi was a postdoctoral fellow at University of California, San Francisco (UCSF) with Steven Rosen, where she studied the activity of endothelial oligosaccharides in promoting cell adhesion at inflammation sites.[23][24] While working with Rosen at UCSF, Bertozzi was able to modify the protein and sugar molecules in the walls of living cells so that the cells accept foreign materials such as implants.[25]

In 1996 Bertozzi became a faculty member in the UC Berkeley College of Chemistry[26] and a faculty scientist at Lawrence Berkeley National Laboratory, where she served as the director of the Molecular Foundry.[23][27] She has been an investigator with HHMI since 2000.[6] In 1999, while working with HHMI and at Berkeley, she founded the field of bioorthogonal chemistry and coined the term in 2003.[28][29][30] This new field and technique allows researchers to chemically modify molecules in living organisms and not interrupt the processes of the cell.[31] In 2015, Bertozzi moved to Stanford University to join the ChEM-H Institute.[32]

Bertozzi studies the glycobiology of underlying diseases such as cancer, inflammatory disorders such as arthritis, and infectious diseases such as tuberculosis. In particular, Bertozzi has advanced the understanding of cell surface oligosaccharides involved in cell recognition and inter-cellular communication. Bertozzi has applied the techniques of bioorthogonal chemistry to study glycocalyx, the sugars that surround the cell membrane. Her discoveries have advanced the field of biotherapeutics.[33] Her lab has also developed tools for research. One such development is creating chemical tools for studying glycans in living systems.[6] Her lab's development of nanotechnologies which probe biological systems lead to the development of a fast point-of-care tuberculosis test in 2018.[34][35] In 2017, due to her lab's discovery of linking the sugars on the surface of cancer cells and their ability to avoid the immune system defenses, she was invited to speak at Stanford's TED talk, giving a talk entitled "What the sugar coating on your cells is trying to tell you".[36]

Biotechnology startups edit

In 2001, Bertozzi and Steve Rosen co-founded Thios Pharmaceuticals in Emeryville, California, the first company to target sulfation pathways.[37] Thios Pharmaceuticals dissolved in 2005.[38]

In 2008, Bertozzi founded a startup of her own: Redwood Bioscience also in Emeryville, California.[39] Redwood Bioscience is a biotechnology company that uses SMARTag, a site-specific protein modification technology that allows small drugs to attach to sites on the proteins and can be used to help fight cancers.[20][40] Redwood Bioscience was acquired by Catalent Pharma Solutions in 2014. Bertozzi remains a part of the advisory board for the biologics sector of the company.[40]

In 2014, she co-founded Enable Biosciences[28] of South San Francisco, California.[41] It focuses on biotechnologies for at-home diagnoses for type 1 diabetes, HIV, and other diseases.[28][42]

Bertozzi became a co-founder of Palleon Pharma of Waltham, Massachusetts, in 2015.[43] Palleon Pharma focuses on investigating glycoimmune checkpoint inhibitors as a potential treatment for cancer.[44]

In 2017, Bertozzi helped found InterVenn Biosciences, which uses mass spectrometry and artificial intelligence to enhance glycoproteomics for target and biomarker discovery, ovarian cancer diagnostics, and predicting the successes and failures of clinical trials.[28][45]

She co-founded Grace Science Foundation in 2018. The foundation focuses on curing NGLY1 deficiency through developing therapeutics that are efficient and inexpensive.[46]

In 2019, she co-founded both OliLux Biosciences and Lycia Therapeutics. OliLux Biosciences develops new methods for tuberculosis detection.[28][47] The founding of Lycia Therapeutics occurred when Bertozzi's group discovered lysosome-targeting chimeras (LYTACs). The new molecule class may be able to degrade some cardiovascular disease and cancer targets.[48] Lycia Therapeutics focuses on developing technology which utilizes lysosome-targeting chimeras (LYTACs).[28]

Bertozzi also previously served on the research advisory board of several pharmaceutical companies including GlaxoSmithKline, and until 2021 Eli Lilly.[49]

Publications edit

Bertozzi has over 600 publications on Web of Science; the most cited are:

  • Sletten, EM; Bertozzi, CR (2009). "Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality". Angewandte Chemie International Edition in English. 48 (38): 6974–98. doi:10.1002/anie.200900942. PMC 2864149. PMID 19714693.
  • Bertozzi, Carolyn R.; Kiessling, Laura L. (2001). "Chemical Glycobiology". Science. 291 (5512): 2357–64. Bibcode:2001Sci...291.2357B. doi:10.1126/science.1059820. PMID 11269316. S2CID 9585674.
  • Saxon, Eliana; Bertozzi, Carolyn R. (2000). "Cell Surface Engineering by a Modified Staudinger Reaction". Science. 287 (5460): 2007–10. Bibcode:2000Sci...287.2007S. doi:10.1126/science.287.5460.2007. PMID 10720325. S2CID 19720277.
  • Agard, Nicholas J.; Prescher, Jennifer A.; Bertozzi, Carolyn R. (2005). "A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems". Journal of the American Chemical Society. 126 (46): 15046–15047. doi:10.1021/ja044996f. PMID 15547999.
  • Dube, DH; Bertozzi, CR (2005). "Glycans in cancer and inflammation—potential for therapeutics and diagnostics". Nature Reviews Drug Discovery. 4 (6): 477–88. doi:10.1038/nrd1751. PMID 15931257. S2CID 22525932.

Awards and honors edit

 
Carolyn Bertozzi, receiving the Emanuel Merck Lectureship in 2011

Personal life edit

Bertozzi grew up in Lexington, Massachusetts, the daughter of the late Norma Gloria (Berringer) and William Bertozzi.[88] Her father was of Italian descent.[89] Her maternal grandparents were from Nova Scotia, Canada.[14] She has two sisters, one of whom, Andrea Bertozzi, is on the mathematics faculty at the University of California, Los Angeles.[90] Her father was a physics professor at the Massachusetts Institute of Technology.[91][23]

Bertozzi and her two sisters grew up around science. Because their father was a physics professor, when asked what she and her sisters wanted to be when they grew up, the answer was unanimous: a nuclear physicist. The three girls would attend MIT camps, as their father dreamt that they would attend MIT due to a "mixture of pride and the promise of free tuition." To William's dismay, Carolyn attended Harvard instead because the school offered strengths outside of just science.[23]

Bertozzi briefly considered a career in music. In high school, she won several awards for music compositions and musical accomplishments. Her talent on the keyboard earned her offers as a music major from several university rock bands, but she felt that she was "always centered on the sciences".[23] Bertozzi is a lesbian and has been out since the late 1980s.[92]

References edit

  1. ^ Prescher, Jennifer Ann (2006). Probing Glycosylation in Living Animals with Bioorthogonal Chemistries (PhD thesis). University of California, Berkeley. OCLC 892833679. ProQuest 305348554.
  2. ^ "Carolyn R. Bertozzi". HHMI.org. Retrieved February 5, 2020.
  3. ^ "Carolyn Bertozzi | Department of Chemistry". chemistry.stanford.edu. Retrieved March 16, 2022.
  4. ^ Adams, Amy. "Stanford chemist explains excitement of chemistry to students, the public". Stanford News. Retrieved July 19, 2015.
  5. ^ "Carolyn Bertozzi honored by GLBT organization". UC Berkeley News. February 27, 2007. Retrieved February 8, 2013.
  6. ^ a b c . HHMI. Archived from the original on May 16, 2013. Retrieved February 8, 2013.
  7. ^ "Carolyn Bertozzi, Organic Chemist". MacArthur Foundation. Retrieved February 3, 2015.
  8. ^ Wang, Linda. "Carolyn Bertozzi To Lead ACS Central Science | Chemical & Engineering News". cen.acs.org. Retrieved August 19, 2015.
  9. ^ "Alla lincea Carolyn Bertozzi uno dei Nobel per la Chimica 2022" [Carolyn Bertozzi one of the 2022 Nobel Prize winners in Chemistry]. www.lincei.it (in Italian). Accademia Nazionale dei Lincei. Retrieved October 7, 2022.
  10. ^ a b Cassell, Heather (February 22, 2007). "Two Bay Area gay scientists honored". Bay Area Reporter. Retrieved October 5, 2022.
  11. ^ a b "NOGLSTP to Honor Bertozzi, Gill, Mauzey, and Bannochie at 2007 Awards Ceremony in February". NOGLSTP. Retrieved February 19, 2019.
  12. ^ a b "Press release: The Nobel Prize in Chemistry 2022" (Press release). The Nobel Prize. October 5, 2022.
  13. ^ Grabowski, Joseph J.; Bertozzi, Carolyn R.; Jacobsen, John R.; Jain, Ahamindra; Marzluff, Elaine M.; Suh, Annie Y. (1992). "Fluorescence probes in biochemistry: An examination of the non-fluorescent behavior of dansylamide by photoacoustic calorimetry". Analytical Biochemistry. 207 (2): 214–26. doi:10.1016/0003-2697(92)90003-P. PMID 1481973.
  14. ^ a b "Oral history interview with Carolyn R. Bertozzi".
  15. ^ . NIGMS. Archived from the original on October 5, 2017. Retrieved February 8, 2013.
  16. ^ Houlton, Sarah (January 12, 2018). "Carolyn Bertozzi". Chemistry World. Royal Society of Chemistry. Retrieved October 7, 2020.
  17. ^ Stewart, Eric (March 27, 2017). "Carolyn Bertozzi' s Winding Road to an Extraordinary Career". inChemistry. American Chemical Society. Retrieved February 17, 2020.
  18. ^ Bertozzi, Carolyn Ruth. Synthesis and biological activity of carbon-linked glycosides (Ph.D. thesis). University of California, Berkeley. OCLC 30660316. ProQuest 304068526.
  19. ^ "Bertozzi: Infectious In Her Enthusiasm". Chemical & Engineering News. 78 (5): 26–35. January 31, 2000.
  20. ^ a b . lemelson.mit.edu. Archived from the original on August 10, 2020. Retrieved February 5, 2020.
  21. ^ Azvolunsky, Anna (May 31, 2016). "Carolyn Bertozzi: Glycan Chemist". The Scientist. Retrieved October 7, 2020.
  22. ^ Baker, Mitzi (March 22, 2006). "Bednarski, pioneer of new cancer therapies, dies at 47". Stanford University. Retrieved October 15, 2022.
  23. ^ a b c d e Davis, T. (February 16, 2010). "Profile of Carolyn Bertozzi". Proceedings of the National Academy of Sciences. 107 (7): 2737–2739. Bibcode:2010PNAS..107.2737D. doi:10.1073/pnas.0914469107. PMC 2840349. PMID 20160128.
  24. ^ Gardiner, Mary Beth (Winter 2005). "The Right Chemistry" (PDF). HHMI Bulletin: 8–12. Retrieved October 24, 2015.
  25. ^ . Chemical Heritage Foundation. Archived from the original on July 12, 2016.
  26. ^ Sanders, Robert (October 5, 2022). "Chemistry Nobelist Carolyn Bertozzi's years at UC Berkeley". Berkeley News. Retrieved October 15, 2022.
  27. ^ "Former Berkeley Lab Scientist Carolyn Bertozzi Wins 2022 Nobel Prize in Chemistry". Retrieved September 7, 2022.
  28. ^ a b c d e f "Carolyn Bertozzi's glycorevolution". Chemical & Engineering News. Retrieved February 12, 2020.
  29. ^ "NIHF Inductee Carolyn Bertozzi Invented Bioorthogonal Chemistry". www.invent.org. Retrieved February 5, 2020.
  30. ^ Sletten, Ellen M.; Bertozzi, Carolyn R. (September 20, 2011). "From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions". Accounts of Chemical Research. 44 (9): 666–676. doi:10.1021/ar200148z. ISSN 0001-4842. PMC 3184615. PMID 21838330.
  31. ^ Sletten, Ellen M.; Bertozzi, Carolyn R. (2009). "Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality". Angewandte Chemie International Edition in English. 48 (38): 6974–6998. doi:10.1002/anie.200900942. ISSN 1433-7851. PMC 2864149. PMID 19714693.
  32. ^ . bertozzigroup.stanford.edu. Archived from the original on August 6, 2019. Retrieved April 13, 2018.
  33. ^ Xiao, Han; Woods, Elliot C.; Vukojicic, Petar; Bertozzi, Carolyn R. (August 22, 2016). "Precision glycocalyx editing as a strategy for cancer immunotherapy". Proceedings of the National Academy of Sciences. 113 (37): 10304–10309. Bibcode:2016PNAS..11310304X. doi:10.1073/pnas.1608069113. ISSN 0027-8424. PMC 5027407. PMID 27551071.
  34. ^ a b . MIT. Archived from the original on August 10, 2020. Retrieved May 13, 2014.
  35. ^ Kamariza, Mireille; Shieh, Peyton; Ealand, Christopher S.; Peters, Julian S.; Chu, Brian; Rodriguez-Rivera, Frances P.; Babu Sait, Mohammed R.; Treuren, William V.; Martinson, Neil; Kalscheuer, Rainer; Kana, Bavesh D. (2018). "Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe". Science Translational Medicine. 10 (430): eaam6310. doi:10.1126/scitranslmed.aam6310. ISSN 1946-6242. PMC 5985656. PMID 29491187.
  36. ^ Bertozzi, Carolyn. "Carolyn Bertozzi | Speaker | TED". www.ted.com. Retrieved February 5, 2020.
  37. ^ McCarthy, Alice A. (February 2004). "Thios Pharmaceuticals Targeting Sulfation Pathways" (PDF). Chemistry & Biology. 11 (2): 147–148. doi:10.1016/j.chembiol.2004.02.008. PMID 15123271.
  38. ^ "Thios Pharmaceuticals | www.inknowvation.com". www.inknowvation.com. Retrieved January 27, 2023.
  39. ^ McCook, Alison (March 6, 2013). "Women in Biotechnology: Barred from the Boardroom". Scientific American. Retrieved October 24, 2015.
  40. ^ a b "Redwood Bioscience Inc. | IPIRA". ipira.berkeley.edu. Retrieved February 5, 2020.
  41. ^ "Contact". Enable Biosciences. Retrieved October 13, 2022.
  42. ^ "Enable Biosciences, Inc. | IPIRA". ipira.berkeley.edu. Retrieved February 12, 2020.
  43. ^ . Archived from the original on July 6, 2019. Retrieved October 5, 2022.
  44. ^ "Palleon Pharma". MassBio. Retrieved May 28, 2020.
  45. ^ "InterVenn Biosciences | AI-Driven Mass Spectrometry". intervenn.bio. Retrieved February 12, 2020.
  46. ^ . rarediseases.info.nih.gov. Archived from the original on October 22, 2020. Retrieved February 12, 2020.
  47. ^ Dinkele, Ryan; Gessner, Sophia; Koch, Anastasia S.; Morrow, Carl; Gqada, Melitta; Kamariza, Mireille; Bertozzi, Carolyn R.; Smith, Brian; McLoud, Courtney; Kamholz, Andrew; Bryden, Wayne (December 27, 2019). "Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis bioaerosols". bioRxiv: 2019.12.23.887729. doi:10.1101/2019.12.23.887729. S2CID 213539003.
  48. ^ Banik, Steven; Pedram, Kayvon; Wisnovsky, Simon; Riley, Nicholas; Bertozzi, Carolyn (November 20, 2019). "Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins". Figshare. doi:10.26434/chemrxiv.7927061.v2. S2CID 213002729.
  49. ^ Company, Eli Lilly and. "Lilly Announces that Professor Carolyn Bertozzi has Resigned from its Board of Directors". www.prnewswire.com (Press release). Retrieved March 16, 2022.
  50. ^ Chuang, Theodore D. (December 7, 1987). "Harvard Phi Beta Kappa Inductees Announced | News | The Harvard Crimson". www.thecrimson.com. from the original on September 10, 2013. Retrieved June 1, 2021.
  51. ^ a b c d e "Dr. Bertozzi to Speak at Drug Discovery Symposium". News Center. November 4, 2002. Retrieved June 1, 2021.
  52. ^ "Horace S. Isbell Award". ACS Carbohydrate. Retrieved June 1, 2021.
  53. ^ . Arnold and Mabel Beckman Foundation. Archived from the original on August 2, 2018. Retrieved August 1, 2018.
  54. ^ "Arthur C. Cope Scholar Awards". American Chemical Society. Retrieved June 1, 2021.
  55. ^ a b c d "Major Awards & Honors | College of Chemistry". chemistry.berkeley.edu. Retrieved June 1, 2021.
  56. ^ "President Honors Outstanding Young Scientists". clintonwhitehouse4.archives.gov. Retrieved September 7, 2019.
  57. ^ a b Korte, Andrea (October 5, 2022). "AAAS Fellows Carolyn Bertozzi and K. Barry Sharpless Receive Nobel Prize in Chemistry | American Association for the Advancement of Science". American Association for the Advancement of Science. Retrieved October 29, 2022.
  58. ^ a b "UC Berkeley chemist, biologist, entrepreneur awarded $500,000 Lemelson–MIT Prize | Research UC Berkeley". vcresearch.berkeley.edu. Retrieved June 1, 2021.
  59. ^ "Book of Members, 1780–2010: Chapter B" (PDF). American Academy of Arts and Sciences. Retrieved June 24, 2011.
  60. ^ "05.03.2005 – Three UC Berkeley faculty named to National Academy of Sciences". www.berkeley.edu. Retrieved September 7, 2019.
  61. ^ "Ernst Schering Prize 2007 – Schering Stiftung". Retrieved June 1, 2021.
  62. ^ Kamerling, Johannis P. (March 1, 2008). "The Roy L. Whistler International Award in Carbohydrate Chemistry 2008". Glycobiology. 18 (3): 209. doi:10.1093/glycob/cwn005. ISSN 0959-6658. PMID 18326004.
  63. ^ "List of Members". www.leopoldina.org. Retrieved October 8, 2017.
  64. ^ "ACS May Gibbs Award Meeting". archive.chicagoacs.net. Retrieved October 5, 2022.
  65. ^ "Nichols Medal". newyorkacs.online. Retrieved June 1, 2021.
  66. ^ "Carolyn Bertozzi Wins Harrison Howe Award | February 23, 2009, Issue – Vol. 87 Issue 8 | Chemical & Engineering News". cen.acs.org. Retrieved September 7, 2019.
  67. ^ "Two UC Berkeley faculty named to Institute of Medicine". Berkeley News. November 30, 2001. Retrieved February 10, 2020.
  68. ^ "Bioorganic & Medicinal Chemistry Letters | Tetrahedron Young Investigator Award 2011: Carolyn R. Bertozzi | ScienceDirect.com". www.sciencedirect.com. Retrieved September 7, 2019.
  69. ^ "EM Lectureship – Research | Merck KGaA, Darmstadt, Germany". www.emdgroup.com. Retrieved June 1, 2021.
  70. ^ "Simmons among nine honorary degree recipients". Brown University. May 16, 2012. Retrieved May 28, 2014.
  71. ^ "Heinrich Wieland Prize 2012 goes to Carolyn R. Bertozzi". Boehringer Ingelheim Foundation. October 18, 2012. Archived from the original on July 2, 2014. Retrieved June 30, 2014.
  72. ^ "Carolyn Bertozzi and George Smoot Elected to National Academy of Inventors | Research UC Berkeley". vcresearch.berkeley.edu. Retrieved September 7, 2019.
  73. ^ . www2.rimls.nl. Archived from the original on June 16, 2021. Retrieved September 7, 2019.
  74. ^ "Carolyn Bertozzi". Bertozzi Group. Retrieved October 5, 2022.
  75. ^ "Arthur C. Cope Awards". August 25, 2016.
  76. ^ "Distinguished scientists elected as Fellows and Foreign Members of the Royal Society". The Royal Society. May 9, 2018. Retrieved May 10, 2018.
  77. ^ "Carolyn Bertozzi". www.nasonline.org. Retrieved January 22, 2020.
  78. ^ "Chemistry for the Future Solvay Prize – The 2020 Laureate". Solvay. Retrieved February 5, 2020.
  79. ^ "F.A. Cotton Medal". chem.tamu.edu. Retrieved June 9, 2020.
  80. ^ "Carolyn R. Bertozzi". February 8, 2022. Retrieved October 5, 2022.
  81. ^ "Winners of Heineken Prizes 2022 announced". Heineken. June 8, 2022. Retrieved October 3, 2022.
  82. ^ Dickson Prize 2022
  83. ^ "Welch Award in Chemistry". Welch. Retrieved October 5, 2022.
  84. ^ "Bijvoet Medals awarded to Carolyn Bertozzi and Vishva Dixit". Utrecht University. October 3, 2022. Retrieved October 3, 2022.
  85. ^ Jilani, Zaid (February 10, 2022). "Carolyn R. Bertozzi Wins 2022 AAAS Lifetime Mentor Award | American Association for the Advancement of Science". American Association for the Advancement of Science. Retrieved October 29, 2022.
  86. ^ "Roger Adams Award". www.organicdivision.org. Retrieved February 28, 2023.
  87. ^ "Nobel Laureate Carolyn R. Bertozzi, PhD, to Receive 2023 AACR Award for Outstanding Achievement in Chemistry in Cancer Research". American Association for Cancer Research (AACR). Retrieved January 6, 2024.
  88. ^ "NORMA GLORIA BERTOZZI Obituary (2021) Boston Globe". Legacy.com.
  89. ^ "Italian American Scientist Carolyn Bertozzi Wins the Nobel Prize in Chemistry". October 5, 2022.
  90. ^ "UCLA Math Department Faculty". Retrieved June 4, 2012.
  91. ^ "MIT Physics Department Faculty". Retrieved June 4, 2012.
  92. ^ Navals, Pauline (April 5, 2022). "ONE ON ONE WITH CAROLYN BERTOZZI". Chemical & Engineering News.

External links edit

  • Official website of Bertozzi Research Group
  • What the sugar coating on your cells is trying to tell you – TED Talk

carolyn, bertozzi, carolyn, ruth, bertozzi, born, october, 1966, american, chemist, nobel, laureate, known, wide, ranging, work, spanning, both, chemistry, biology, coined, term, bioorthogonal, chemistry, chemical, reactions, compatible, with, living, systems,. Carolyn Ruth Bertozzi born October 10 1966 is an American chemist and Nobel laureate known for her wide ranging work spanning both chemistry and biology She coined the term bioorthogonal chemistry 2 for chemical reactions compatible with living systems Her recent efforts include synthesis of chemical tools to study cell surface sugars called glycans and how they affect diseases such as cancer inflammation and viral infections like COVID 19 3 At Stanford University she holds the Anne T and Robert M Bass Professorship in the School of Humanities and Sciences 4 Bertozzi is also an Investigator at the Howard Hughes Medical Institute HHMI 5 and is the former director of the Molecular Foundry a nanoscience research center at Lawrence Berkeley National Laboratory 6 Carolyn BertozziBertozzi in 2022BornCarolyn Ruth Bertozzi 1966 10 10 October 10 1966 age 57 Boston Massachusetts U S EducationHarvard University AB University of California Berkeley MS PhD Known forBioorthogonal chemistryRelativesAndrea Bertozzi sister AwardsMacArthur Foundation Fellowship 1999 ACS Award in Pure Chemistry 2001 Lemelson MIT Prize 2010 Heinrich Wieland Prize 2012 Wolf Prize 2022 Dickson Prize 2022 Welch Award in Chemistry 2022 Nobel Prize in Chemistry 2022 Scientific careerFieldsChemistryInstitutionsStanford UniversityUniversity of California BerkeleyLawrence Berkeley National LaboratoryUniversity of California San FranciscoThesisSynthesis and biological activity of carbon linked glycosides 1993 Doctoral advisorMark D BednarskiDoctoral studentsLisa Marcaurelle Howard Hang Mireille Kamariza Lara Mahal Jennifer Prescher 1 External videos What the sugar coating on your cells is trying to tell you TEDx Stanford Carolyn R Bertozzi Wins 2022 AAAS Lifetime Mentor Award AAAS 10 February 2022She received the MacArthur genius award at age 33 7 In 2010 she was the first woman to receive the prestigious Lemelson MIT Prize faculty award She is a member of the National Academy of Sciences 2005 the Institute of Medicine 2011 and the National Academy of Inventors 2013 In 2014 it was announced that Bertozzi would lead ACS Central Science the American Chemical Society s first peer reviewed open access journal which offers all content free to the public 8 Since 2021 she has been a member of the Accademia dei Lincei 9 As an open lesbian in academia and science Bertozzi has been a role model for students and colleagues 10 11 Bertozzi was awarded the 2022 Nobel Prize in Chemistry jointly with Morten P Meldal and Karl Barry Sharpless for the development of click chemistry and bioorthogonal chemistry 12 Contents 1 Education 2 Career and research 2 1 Biotechnology startups 2 2 Publications 2 3 Awards and honors 3 Personal life 4 References 5 External linksEducation editCarolyn Bertozzi received her B A summa cum laude in chemistry from Harvard University where she worked with Professor Joe Grabowski on the design and construction of a photoacoustic calorimeter 13 Grabowski was impressed with her work and required Bertozzi to write a thesis on this project which was submitted and Bertozzi won the Thomas T Hoopes Undergraduate Thesis Prize with a large prize money 14 While an undergraduate she played in several bands notably Bored of Education with future Rage Against the Machine guitarist Tom Morello 15 16 After graduating from Harvard in 1988 she worked at Bell Labs with Chris Chidsey 17 Bertozzi completed her Ph D in chemistry at University of California Berkeley in 1993 with Mark Bednarski working on the chemical synthesis of oligosaccharide analogs 18 19 While at Berkeley she discovered that viruses can bind to sugars in the body 20 The discovery led to her field of research glycobiology During Bertozzi s third year of graduate school Bednarski was diagnosed with colon cancer which resulted in him taking a leave of absence and changing his career path by enrolling in medical school This left Bertozzi and the rest of the lab to complete their Ph D work with no direct supervision 21 22 Career and research editAfter graduating from Berkeley with a Ph D Bertozzi was a postdoctoral fellow at University of California San Francisco UCSF with Steven Rosen where she studied the activity of endothelial oligosaccharides in promoting cell adhesion at inflammation sites 23 24 While working with Rosen at UCSF Bertozzi was able to modify the protein and sugar molecules in the walls of living cells so that the cells accept foreign materials such as implants 25 In 1996 Bertozzi became a faculty member in the UC Berkeley College of Chemistry 26 and a faculty scientist at Lawrence Berkeley National Laboratory where she served as the director of the Molecular Foundry 23 27 She has been an investigator with HHMI since 2000 6 In 1999 while working with HHMI and at Berkeley she founded the field of bioorthogonal chemistry and coined the term in 2003 28 29 30 This new field and technique allows researchers to chemically modify molecules in living organisms and not interrupt the processes of the cell 31 In 2015 Bertozzi moved to Stanford University to join the ChEM H Institute 32 Bertozzi studies the glycobiology of underlying diseases such as cancer inflammatory disorders such as arthritis and infectious diseases such as tuberculosis In particular Bertozzi has advanced the understanding of cell surface oligosaccharides involved in cell recognition and inter cellular communication Bertozzi has applied the techniques of bioorthogonal chemistry to study glycocalyx the sugars that surround the cell membrane Her discoveries have advanced the field of biotherapeutics 33 Her lab has also developed tools for research One such development is creating chemical tools for studying glycans in living systems 6 Her lab s development of nanotechnologies which probe biological systems lead to the development of a fast point of care tuberculosis test in 2018 34 35 In 2017 due to her lab s discovery of linking the sugars on the surface of cancer cells and their ability to avoid the immune system defenses she was invited to speak at Stanford s TED talk giving a talk entitled What the sugar coating on your cells is trying to tell you 36 Biotechnology startups edit In 2001 Bertozzi and Steve Rosen co founded Thios Pharmaceuticals in Emeryville California the first company to target sulfation pathways 37 Thios Pharmaceuticals dissolved in 2005 38 In 2008 Bertozzi founded a startup of her own Redwood Bioscience also in Emeryville California 39 Redwood Bioscience is a biotechnology company that uses SMARTag a site specific protein modification technology that allows small drugs to attach to sites on the proteins and can be used to help fight cancers 20 40 Redwood Bioscience was acquired by Catalent Pharma Solutions in 2014 Bertozzi remains a part of the advisory board for the biologics sector of the company 40 In 2014 she co founded Enable Biosciences 28 of South San Francisco California 41 It focuses on biotechnologies for at home diagnoses for type 1 diabetes HIV and other diseases 28 42 Bertozzi became a co founder of Palleon Pharma of Waltham Massachusetts in 2015 43 Palleon Pharma focuses on investigating glycoimmune checkpoint inhibitors as a potential treatment for cancer 44 In 2017 Bertozzi helped found InterVenn Biosciences which uses mass spectrometry and artificial intelligence to enhance glycoproteomics for target and biomarker discovery ovarian cancer diagnostics and predicting the successes and failures of clinical trials 28 45 She co founded Grace Science Foundation in 2018 The foundation focuses on curing NGLY1 deficiency through developing therapeutics that are efficient and inexpensive 46 In 2019 she co founded both OliLux Biosciences and Lycia Therapeutics OliLux Biosciences develops new methods for tuberculosis detection 28 47 The founding of Lycia Therapeutics occurred when Bertozzi s group discovered lysosome targeting chimeras LYTACs The new molecule class may be able to degrade some cardiovascular disease and cancer targets 48 Lycia Therapeutics focuses on developing technology which utilizes lysosome targeting chimeras LYTACs 28 Bertozzi also previously served on the research advisory board of several pharmaceutical companies including GlaxoSmithKline and until 2021 Eli Lilly 49 Publications edit Bertozzi has over 600 publications on Web of Science the most cited are Sletten EM Bertozzi CR 2009 Bioorthogonal Chemistry Fishing for Selectivity in a Sea of Functionality Angewandte Chemie International Edition in English 48 38 6974 98 doi 10 1002 anie 200900942 PMC 2864149 PMID 19714693 Bertozzi Carolyn R Kiessling Laura L 2001 Chemical Glycobiology Science 291 5512 2357 64 Bibcode 2001Sci 291 2357B doi 10 1126 science 1059820 PMID 11269316 S2CID 9585674 Saxon Eliana Bertozzi Carolyn R 2000 Cell Surface Engineering by a Modified Staudinger Reaction Science 287 5460 2007 10 Bibcode 2000Sci 287 2007S doi 10 1126 science 287 5460 2007 PMID 10720325 S2CID 19720277 Agard Nicholas J Prescher Jennifer A Bertozzi Carolyn R 2005 A Strain Promoted 3 2 Azide Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems Journal of the American Chemical Society 126 46 15046 15047 doi 10 1021 ja044996f PMID 15547999 Dube DH Bertozzi CR 2005 Glycans in cancer and inflammation potential for therapeutics and diagnostics Nature Reviews Drug Discovery 4 6 477 88 doi 10 1038 nrd1751 PMID 15931257 S2CID 22525932 Awards and honors edit nbsp Carolyn Bertozzi receiving the Emanuel Merck Lectureship in 20111987 Phi Beta Kappa 50 1997 Alfred P Sloan Research Fellowship 51 1997 Horace S Isbell Award in Carbohydrate Chemistry 52 1998 Glaxo Wellcome Scholars Award 51 1998 Beckman Young Investigators Award 53 1999 Arthur C Cope Scholar Award of the American Chemical Society 54 1999 Camille Dreyfus Teacher Scholar Award 51 1999 MacArthur Fellowship 55 2000 Presidential Early Career Award for Scientists and Engineers 56 2000 Merck Academic Development Program Award 51 2001 UC Berkeley Distinguished Teaching Award 55 2001 ACS Award in Pure Chemistry 51 2001 Donald Sterling Noyce Prize for Excellence in Undergraduate Teaching 55 2001 Fellow of the American Association for the Advancement of Science 57 2002 Irving Sigal Young Investigator Award of the Protein Society 58 2003 Fellow of the American Academy of Arts and Sciences 59 2004 Agnes Fay Morgan Research Award of Iota Sigma Pi citation needed 2005 Havinga Medal Univ Leiden citation needed 2005 Member of the National Academy of Sciences 55 2005 T Z and Irmgard Chu Distinguished Professorship in Chemistry 60 2007 Ernst Schering Prize 61 2007 LGBTQ Scientist of the Year Award from the National Organization of Gay and Lesbian Scientists and Technical Professionals 10 11 2008 Li Ka Shing Women in Science Award 58 2008 Roy L Whistler International Award in Carbohydrate Chemistry 62 2008 Member of the German Academy of Sciences Leopoldina 63 2008 Willard Gibbs Award 64 2009 William H Nichols Medal 65 2009 Harrison Howe Award 66 2009 Albert Hofmann Medal Univ Zurich citation needed 2010 Lemelson MIT Prize 34 2010 Royal Society of Chemistry Organic Division Bioorganic Chemistry Award 2011 Member of the Institute of Medicine 67 2011 Tetrahedron Young Investigator Award for Bioorganic and Medicinal Chemistry 68 2011 Emanuel Merck Lectureship 69 2012 Honorary Doctorate of Science from Brown University 70 2012 Heinrich Wieland Prize 71 2013 Elected Fellow of the National Academy of Inventors 72 2013 Hans Bloemendal Award 73 2015 UCSF 150th Anniversary Alumni Excellence Awards 74 2017 Arthur C Cope Award 75 2018 Foreign Member of the Royal Society ForMemRS 76 2020 John J Carty Award for the Advancement of Science 77 2020 Chemistry for the Future Solvay Prize 78 2020 F A Cotton Medal for Excellence in Chemical Research 79 2022 Wolf Prize in Chemistry 80 2022 Dr H P Heineken Prize for Biochemistry and Biophysics 81 2022 Dickson Prize in Medicine 82 2022 Welch Award in Chemistry 83 2022 Bijvoet Medal of the Bijvoet Centre for Biomolecular Research of Utrecht University 84 2022 Lifetime Mentor Award American Association for the Advancement of Science 85 57 2022 Nobel Prize in Chemistry 12 2023 Roger Adams Award 86 2023 AACR Award for Outstanding Achievement in Chemistry in Cancer Research 87 Personal life editBertozzi grew up in Lexington Massachusetts the daughter of the late Norma Gloria Berringer and William Bertozzi 88 Her father was of Italian descent 89 Her maternal grandparents were from Nova Scotia Canada 14 She has two sisters one of whom Andrea Bertozzi is on the mathematics faculty at the University of California Los Angeles 90 Her father was a physics professor at the Massachusetts Institute of Technology 91 23 Bertozzi and her two sisters grew up around science Because their father was a physics professor when asked what she and her sisters wanted to be when they grew up the answer was unanimous a nuclear physicist The three girls would attend MIT camps as their father dreamt that they would attend MIT due to a mixture of pride and the promise of free tuition To William s dismay Carolyn attended Harvard instead because the school offered strengths outside of just science 23 Bertozzi briefly considered a career in music In high school she won several awards for music compositions and musical accomplishments Her talent on the keyboard earned her offers as a music major from several university rock bands but she felt that she was always centered on the sciences 23 Bertozzi is a lesbian and has been out since the late 1980s 92 References edit Prescher Jennifer Ann 2006 Probing Glycosylation in Living Animals with Bioorthogonal Chemistries PhD thesis University of California Berkeley OCLC 892833679 ProQuest 305348554 Carolyn R Bertozzi HHMI org Retrieved February 5 2020 Carolyn Bertozzi Department of Chemistry chemistry stanford edu Retrieved March 16 2022 Adams Amy Stanford chemist explains excitement of chemistry to students the public Stanford News Retrieved July 19 2015 Carolyn Bertozzi honored by GLBT organization UC Berkeley News February 27 2007 Retrieved February 8 2013 a b c Carolyn Bertozzi HHMI Archived from the original on May 16 2013 Retrieved February 8 2013 Carolyn Bertozzi Organic Chemist MacArthur Foundation Retrieved February 3 2015 Wang Linda Carolyn Bertozzi To Lead ACS Central Science Chemical amp Engineering News cen acs org Retrieved August 19 2015 Alla lincea Carolyn Bertozzi uno dei Nobel per la Chimica 2022 Carolyn Bertozzi one of the 2022 Nobel Prize winners in Chemistry www lincei it in Italian Accademia Nazionale dei Lincei Retrieved October 7 2022 a b Cassell Heather February 22 2007 Two Bay Area gay scientists honored Bay Area Reporter Retrieved October 5 2022 a b NOGLSTP to Honor Bertozzi Gill Mauzey and Bannochie at 2007 Awards Ceremony in February NOGLSTP Retrieved February 19 2019 a b Press release The Nobel Prize in Chemistry 2022 Press release The Nobel Prize October 5 2022 Grabowski Joseph J Bertozzi Carolyn R Jacobsen John R Jain Ahamindra Marzluff Elaine M Suh Annie Y 1992 Fluorescence probes in biochemistry An examination of the non fluorescent behavior of dansylamide by photoacoustic calorimetry Analytical Biochemistry 207 2 214 26 doi 10 1016 0003 2697 92 90003 P PMID 1481973 a b Oral history interview with Carolyn R Bertozzi Meet Carolyn Bertozzi NIGMS Archived from the original on October 5 2017 Retrieved February 8 2013 Houlton Sarah January 12 2018 Carolyn Bertozzi Chemistry World Royal Society of Chemistry Retrieved October 7 2020 Stewart Eric March 27 2017 Carolyn Bertozzi s Winding Road to an Extraordinary Career inChemistry American Chemical Society Retrieved February 17 2020 Bertozzi Carolyn Ruth Synthesis and biological activity of carbon linked glycosides Ph D thesis University of California Berkeley OCLC 30660316 ProQuest 304068526 Bertozzi Infectious In Her Enthusiasm Chemical amp Engineering News 78 5 26 35 January 31 2000 a b Carolyn Bertozzi Lemelson MIT Program lemelson mit edu Archived from the original on August 10 2020 Retrieved February 5 2020 Azvolunsky Anna May 31 2016 Carolyn Bertozzi Glycan Chemist The Scientist Retrieved October 7 2020 Baker Mitzi March 22 2006 Bednarski pioneer of new cancer therapies dies at 47 Stanford University Retrieved October 15 2022 a b c d e Davis T February 16 2010 Profile of Carolyn Bertozzi Proceedings of the National Academy of Sciences 107 7 2737 2739 Bibcode 2010PNAS 107 2737D doi 10 1073 pnas 0914469107 PMC 2840349 PMID 20160128 Gardiner Mary Beth Winter 2005 The Right Chemistry PDF HHMI Bulletin 8 12 Retrieved October 24 2015 Carolyn Bertozzi Chemical Heritage Foundation Archived from the original on July 12 2016 Sanders Robert October 5 2022 Chemistry Nobelist Carolyn Bertozzi s years at UC Berkeley Berkeley News Retrieved October 15 2022 Former Berkeley Lab Scientist Carolyn Bertozzi Wins 2022 Nobel Prize in Chemistry Retrieved September 7 2022 a b c d e f Carolyn Bertozzi s glycorevolution Chemical amp Engineering News Retrieved February 12 2020 NIHF Inductee Carolyn Bertozzi Invented Bioorthogonal Chemistry www invent org Retrieved February 5 2020 Sletten Ellen M Bertozzi Carolyn R September 20 2011 From Mechanism to Mouse A Tale of Two Bioorthogonal Reactions Accounts of Chemical Research 44 9 666 676 doi 10 1021 ar200148z ISSN 0001 4842 PMC 3184615 PMID 21838330 Sletten Ellen M Bertozzi Carolyn R 2009 Bioorthogonal Chemistry Fishing for Selectivity in a Sea of Functionality Angewandte Chemie International Edition in English 48 38 6974 6998 doi 10 1002 anie 200900942 ISSN 1433 7851 PMC 2864149 PMID 19714693 Carolyn R Bertozzi bertozzigroup stanford edu Archived from the original on August 6 2019 Retrieved April 13 2018 Xiao Han Woods Elliot C Vukojicic Petar Bertozzi Carolyn R August 22 2016 Precision glycocalyx editing as a strategy for cancer immunotherapy Proceedings of the National Academy of Sciences 113 37 10304 10309 Bibcode 2016PNAS 11310304X doi 10 1073 pnas 1608069113 ISSN 0027 8424 PMC 5027407 PMID 27551071 a b Carolyn Bertozzi 2010 Lemelson MIT Prize MIT Archived from the original on August 10 2020 Retrieved May 13 2014 Kamariza Mireille Shieh Peyton Ealand Christopher S Peters Julian S Chu Brian Rodriguez Rivera Frances P Babu Sait Mohammed R Treuren William V Martinson Neil Kalscheuer Rainer Kana Bavesh D 2018 Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe Science Translational Medicine 10 430 eaam6310 doi 10 1126 scitranslmed aam6310 ISSN 1946 6242 PMC 5985656 PMID 29491187 Bertozzi Carolyn Carolyn Bertozzi Speaker TED www ted com Retrieved February 5 2020 McCarthy Alice A February 2004 Thios Pharmaceuticals Targeting Sulfation Pathways PDF Chemistry amp Biology 11 2 147 148 doi 10 1016 j chembiol 2004 02 008 PMID 15123271 Thios Pharmaceuticals www inknowvation com www inknowvation com Retrieved January 27 2023 McCook Alison March 6 2013 Women in Biotechnology Barred from the Boardroom Scientific American Retrieved October 24 2015 a b Redwood Bioscience Inc IPIRA ipira berkeley edu Retrieved February 5 2020 Contact Enable Biosciences Retrieved October 13 2022 Enable Biosciences Inc IPIRA ipira berkeley edu Retrieved February 12 2020 Palleon Pharma Leadership Archived from the original on July 6 2019 Retrieved October 5 2022 Palleon Pharma MassBio Retrieved May 28 2020 InterVenn Biosciences AI Driven Mass Spectrometry intervenn bio Retrieved February 12 2020 Grace Science Foundation rarediseases info nih gov Archived from the original on October 22 2020 Retrieved February 12 2020 Dinkele Ryan Gessner Sophia Koch Anastasia S Morrow Carl Gqada Melitta Kamariza Mireille Bertozzi Carolyn R Smith Brian McLoud Courtney Kamholz Andrew Bryden Wayne December 27 2019 Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis bioaerosols bioRxiv 2019 12 23 887729 doi 10 1101 2019 12 23 887729 S2CID 213539003 Banik Steven Pedram Kayvon Wisnovsky Simon Riley Nicholas Bertozzi Carolyn November 20 2019 Lysosome Targeting Chimeras LYTACs for the Degradation of Secreted and Membrane Proteins Figshare doi 10 26434 chemrxiv 7927061 v2 S2CID 213002729 Company Eli Lilly and Lilly Announces that Professor Carolyn Bertozzi has Resigned from its Board of Directors www prnewswire com Press release Retrieved March 16 2022 Chuang Theodore D December 7 1987 Harvard Phi Beta Kappa Inductees Announced News The Harvard Crimson www thecrimson com Archived from the original on September 10 2013 Retrieved June 1 2021 a b c d e Dr Bertozzi to Speak at Drug Discovery Symposium News Center November 4 2002 Retrieved June 1 2021 Horace S Isbell Award ACS Carbohydrate Retrieved June 1 2021 Carolyn R Bertozzi Arnold and Mabel Beckman Foundation Archived from the original on August 2 2018 Retrieved August 1 2018 Arthur C Cope Scholar Awards American Chemical Society Retrieved June 1 2021 a b c d Major Awards amp Honors College of Chemistry chemistry berkeley edu Retrieved June 1 2021 President Honors Outstanding Young Scientists clintonwhitehouse4 archives gov Retrieved September 7 2019 a b Korte Andrea October 5 2022 AAAS Fellows Carolyn Bertozzi and K Barry Sharpless Receive Nobel Prize in Chemistry American Association for the Advancement of Science American Association for the Advancement of Science Retrieved October 29 2022 a b UC Berkeley chemist biologist entrepreneur awarded 500 000 Lemelson MIT Prize Research UC Berkeley vcresearch berkeley edu Retrieved June 1 2021 Book of Members 1780 2010 Chapter B PDF American Academy of Arts and Sciences Retrieved June 24 2011 05 03 2005 Three UC Berkeley faculty named to National Academy of Sciences www berkeley edu Retrieved September 7 2019 Ernst Schering Prize 2007 Schering Stiftung Retrieved June 1 2021 Kamerling Johannis P March 1 2008 The Roy L Whistler International Award in Carbohydrate Chemistry 2008 Glycobiology 18 3 209 doi 10 1093 glycob cwn005 ISSN 0959 6658 PMID 18326004 List of Members www leopoldina org Retrieved October 8 2017 ACS May Gibbs Award Meeting archive chicagoacs net Retrieved October 5 2022 Nichols Medal newyorkacs online Retrieved June 1 2021 Carolyn Bertozzi Wins Harrison Howe Award February 23 2009 Issue Vol 87 Issue 8 Chemical amp Engineering News cen acs org Retrieved September 7 2019 Two UC Berkeley faculty named to Institute of Medicine Berkeley News November 30 2001 Retrieved February 10 2020 Bioorganic amp Medicinal Chemistry Letters Tetrahedron Young Investigator Award 2011 Carolyn R Bertozzi ScienceDirect com www sciencedirect com Retrieved September 7 2019 EM Lectureship Research Merck KGaA Darmstadt Germany www emdgroup com Retrieved June 1 2021 Simmons among nine honorary degree recipients Brown University May 16 2012 Retrieved May 28 2014 Heinrich Wieland Prize 2012 goes to Carolyn R Bertozzi Boehringer Ingelheim Foundation October 18 2012 Archived from the original on July 2 2014 Retrieved June 30 2014 Carolyn Bertozzi and George Smoot Elected to National Academy of Inventors Research UC Berkeley vcresearch berkeley edu Retrieved September 7 2019 Bloemendal Medal www2 rimls nl Archived from the original on June 16 2021 Retrieved September 7 2019 Carolyn Bertozzi Bertozzi Group Retrieved October 5 2022 Arthur C Cope Awards August 25 2016 Distinguished scientists elected as Fellows and Foreign Members of the Royal Society The Royal Society May 9 2018 Retrieved May 10 2018 Carolyn Bertozzi www nasonline org Retrieved January 22 2020 Chemistry for the Future Solvay Prize The 2020 Laureate Solvay Retrieved February 5 2020 F A Cotton Medal chem tamu edu Retrieved June 9 2020 Carolyn R Bertozzi February 8 2022 Retrieved October 5 2022 Winners of Heineken Prizes 2022 announced Heineken June 8 2022 Retrieved October 3 2022 Dickson Prize 2022 Welch Award in Chemistry Welch Retrieved October 5 2022 Bijvoet Medals awarded to Carolyn Bertozzi and Vishva Dixit Utrecht University October 3 2022 Retrieved October 3 2022 Jilani Zaid February 10 2022 Carolyn R Bertozzi Wins 2022 AAAS Lifetime Mentor Award American Association for the Advancement of Science American Association for the Advancement of Science Retrieved October 29 2022 Roger Adams Award www organicdivision org Retrieved February 28 2023 Nobel Laureate Carolyn R Bertozzi PhD to Receive 2023 AACR Award for Outstanding Achievement in Chemistry in Cancer Research American Association for Cancer Research AACR Retrieved January 6 2024 NORMA GLORIA BERTOZZI Obituary 2021 Boston Globe Legacy com Italian American Scientist Carolyn Bertozzi Wins the Nobel Prize in Chemistry October 5 2022 UCLA Math Department Faculty Retrieved June 4 2012 MIT Physics Department Faculty Retrieved June 4 2012 Navals Pauline April 5 2022 ONE ON ONE WITH CAROLYN BERTOZZI Chemical amp Engineering News External links edit nbsp Scholia has a profile for Carolyn Bertozzi Q7442 Official website of Bertozzi Research Group What the sugar coating on your cells is trying to tell you TED Talk nbsp Wikimedia Commons has media related to Carolyn Bertozzi Carolyn Bertozzi on Nobelprize org nbsp Bertozzi s et al publication list Hardcastle M 2023 QnAs with Carolyn R Bertozzi Proceedings of the National Academy of Sciences of the United States of America 120 1 e2220665120 Bibcode 2023PNAS 12020665H doi 10 1073 pnas 2220665120 PMC 9910447 PMID 36584297 Retrieved from https en wikipedia org w index php title Carolyn Bertozzi amp oldid 1193951079, wikipedia, wiki, book, books, library,

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