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Disodium phosphate

Disodium phosphate (DSP), or disodium hydrogen phosphate, or sodium phosphate dibasic, is an inorganic compound with the chemical formula Na2HPO4. It is one of several sodium phosphates. The salt is known in anhydrous form as well as hydrates Na2HPO4·nH2O, where n is 2, 7, 8, and 12. All are water-soluble white powders. The anhydrous salt is hygroscopic.[1]

Disodium phosphate

  Sodium, Na
  Phosphorus, P
  Oxygen, O
  Hydrogen, H
Names
IUPAC name
Disodium hydrogen phosphate
Other names
  • Acetest
  • Dibasic sodium phosphate
  • Disodium hydrogen orthophosphate
  • Disodium hydrogen phosphate
  • Disodium phosphate
  • Sodium phosphate dibasic
Identifiers
  • 7558-79-4 Y
  • 10028-24-7 (dihydrate) Y
  • 7782-85-6 (heptahydrate) Y
  • 10039-32-4 (dodecahydrate) Y
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:34683 Y
ChEMBL
  • ChEMBL1060 Y
ChemSpider
  • 22625 Y
ECHA InfoCard 100.028.590
EC Number
  • 231-448-7
E number E339(ii) (antioxidants, ...)
  • 24203
RTECS number
  • WC4500000
UNII
  • 22ADO53M6F Y
  • 94255I6E2T (dihydrate) Y
  • 70WT22SF4B (heptahydrate) Y
  • E1W4N241FO (dodecahydrate) Y
  • DTXSID1026039
  • InChI=1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-3 N
    Key: BNIILDVGGAEEIG-UHFFFAOYSA-K N
  • InChI=1/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-3
    Key: BNIILDVGGAEEIG-DFZHHIFOAK
  • OP(=O)([O-])[O-].[Na+].[Na+]
Properties
Na2HPO4
Molar mass
  • 141.96 g/mol (anhydrous)
  • 177.99 g/mol (dihydrate)
  • 268.07 g/mol (heptahydrate)
Appearance White crystalline solid
Odor Odorless
Density 1.7 g/cm3
Melting point 250 °C (482 °F; 523 K) Decomposes
7.7 g/(100 ml) (20 °C)
11.8 g/(100 ml) (25 °C, heptahydrate)
Solubility Insoluble in ethanol
log P −5.8
Acidity (pKa) 12.35
−56.6·10−6 cm3/mol
1.35644 to 1.35717 at 20°C
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Irritant
NFPA 704 (fire diamond)
Health 1: Exposure would cause irritation but only minor residual injury. E.g. turpentineFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
1
0
0
Flash point Non-flammable
Lethal dose or concentration (LD, LC):
17000 mg/kg (rat, oral)
Safety data sheet (SDS) ICSC 1129
Related compounds
Other anions
sodium phosphite
Other cations
Dipotassium phosphate
Diammonium phosphate
Related compounds
Monosodium phosphate
Trisodium phosphate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)

The pH of disodium hydrogen phosphate water solution is between 8.0 and 11.0, meaning it is moderately basic:

HPO2−4 + H2O ⇌ H2PO4 + OH

Production and reactions edit

It can be generated by neutralization of phosphoric acid with sodium hydroxide:

H3PO4 + 2 NaOH → Na2HPO4 + 2 H2O

Industrially It is prepared in a two-step process by treating dicalcium phosphate with sodium bisulfate, which precipitates calcium sulfate:[2]

CaHPO4 + NaHSO4 → NaH2PO4 + CaSO4

In the second step, the resulting solution of monosodium phosphate is partially neutralized:

NaH2PO4 + NaOH → Na2HPO4 + H2O

Uses edit

It is used in conjunction with trisodium phosphate in foods and water softening treatment. In foods, it is used to adjust pH. Its presence prevents coagulation in the preparation of condensed milk. Similarly, it is used as an anti-caking additive in powdered products.[3] It is used in desserts and puddings, e.g. Cream of Wheat to quicken cook time, and Jell-O Instant Pudding for thickening. In water treatment, it retards calcium scale formation.[citation needed] It is also found in some detergents and cleaning agents.[2]

Heating solid disodium phosphate gives the useful compound tetrasodium pyrophosphate:[citation needed]

2 Na2HPO4 → Na4P2O7 + H2O

Laxative edit

Monobasic and dibasic sodium phosphate are used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.[4]

References edit

  1. ^ (PDF). Archived from the original (PDF) on 2011-07-17. Retrieved 2007-03-06.
  2. ^ a b Klaus Schrödter, Gerhard Bettermann, Thomas Staffel, Friedrich Wahl, Thomas Klein, Thomas Hofmann "Phosphoric Acid and Phosphates" in Ullmann’s Encyclopedia of Industrial Chemistry 2008, Wiley-VCH, Weinheim. doi:10.1002/14356007.a19_465.pub3
  3. ^ . Archived from the original on 2017-10-28. Retrieved 2011-09-26.
  4. ^ "Sodium Phosphate, Dibasic, Sodium Phosphate, Monobasic Oral solution". Krames Patient Education. Archived from the original on 2013-01-28. Retrieved 2009-10-29.

External links edit

  •   Media related to Disodium phosphate at Wikimedia Commons solubility in Prophylaxis alcohol

disodium, phosphate, disodium, hydrogen, phosphate, sodium, phosphate, dibasic, inorganic, compound, with, chemical, formula, na2hpo4, several, sodium, phosphates, salt, known, anhydrous, form, well, hydrates, na2hpo4, nh2o, where, water, soluble, white, powde. Disodium phosphate DSP or disodium hydrogen phosphate or sodium phosphate dibasic is an inorganic compound with the chemical formula Na2HPO4 It is one of several sodium phosphates The salt is known in anhydrous form as well as hydrates Na2HPO4 nH2O where n is 2 7 8 and 12 All are water soluble white powders The anhydrous salt is hygroscopic 1 Disodium phosphate Sodium Na Phosphorus P Oxygen O Hydrogen H Names IUPAC name Disodium hydrogen phosphate Other names AcetestDibasic sodium phosphateDisodium hydrogen orthophosphateDisodium hydrogen phosphateDisodium phosphateSodium phosphate dibasic Identifiers CAS Number 7558 79 4 Y10028 24 7 dihydrate Y7782 85 6 heptahydrate Y10039 32 4 dodecahydrate Y 3D model JSmol Interactive image ChEBI CHEBI 34683 Y ChEMBL ChEMBL1060 Y ChemSpider 22625 Y ECHA InfoCard 100 028 590 EC Number 231 448 7 E number E339 ii antioxidants PubChem CID 24203 RTECS number WC4500000 UNII 22ADO53M6F Y94255I6E2T dihydrate Y70WT22SF4B heptahydrate YE1W4N241FO dodecahydrate Y CompTox Dashboard EPA DTXSID1026039 InChI InChI 1S 2Na H3O4P c 1 5 2 3 4 h H3 1 2 3 4 q2 1 p 3 NKey BNIILDVGGAEEIG UHFFFAOYSA K NInChI 1 2Na H3O4P c 1 5 2 3 4 h H3 1 2 3 4 q2 1 p 3Key BNIILDVGGAEEIG DFZHHIFOAK SMILES OP O O O Na Na Properties Chemical formula Na2HPO4 Molar mass 141 96 g mol anhydrous 177 99 g mol dihydrate 268 07 g mol heptahydrate Appearance White crystalline solid Odor Odorless Density 1 7 g cm3 Melting point 250 C 482 F 523 K Decomposes Solubility in water 7 7 g 100 ml 20 C 11 8 g 100 ml 25 C heptahydrate Solubility Insoluble in ethanol log P 5 8 Acidity pKa 12 35 Magnetic susceptibility x 56 6 10 6 cm3 mol Refractive index nD 1 35644 to 1 35717 at 20 C Hazards Occupational safety and health OHS OSH Main hazards Irritant NFPA 704 fire diamond 100 Flash point Non flammable Lethal dose or concentration LD LC LD50 median dose 17000 mg kg rat oral Safety data sheet SDS ICSC 1129 Related compounds Other anions sodium phosphite Other cations Dipotassium phosphateDiammonium phosphate Related compounds Monosodium phosphateTrisodium phosphate Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa N verify what is Y N Infobox references The pH of disodium hydrogen phosphate water solution is between 8 0 and 11 0 meaning it is moderately basic HPO2 4 H2O H2PO 4 OH Contents 1 Production and reactions 2 Uses 2 1 Laxative 3 References 4 External linksProduction and reactions editIt can be generated by neutralization of phosphoric acid with sodium hydroxide H3PO4 2 NaOH Na2HPO4 2 H2O Industrially It is prepared in a two step process by treating dicalcium phosphate with sodium bisulfate which precipitates calcium sulfate 2 CaHPO4 NaHSO4 NaH2PO4 CaSO4 In the second step the resulting solution of monosodium phosphate is partially neutralized NaH2PO4 NaOH Na2HPO4 H2OUses editIt is used in conjunction with trisodium phosphate in foods and water softening treatment In foods it is used to adjust pH Its presence prevents coagulation in the preparation of condensed milk Similarly it is used as an anti caking additive in powdered products 3 It is used in desserts and puddings e g Cream of Wheat to quicken cook time and Jell O Instant Pudding for thickening In water treatment it retards calcium scale formation citation needed It is also found in some detergents and cleaning agents 2 Heating solid disodium phosphate gives the useful compound tetrasodium pyrophosphate citation needed 2 Na2HPO4 Na4P2O7 H2O Laxative edit Monobasic and dibasic sodium phosphate are used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy 4 References edit Physical data pdf PDF Archived from the original PDF on 2011 07 17 Retrieved 2007 03 06 a b Klaus Schrodter Gerhard Bettermann Thomas Staffel Friedrich Wahl Thomas Klein Thomas Hofmann Phosphoric Acid and Phosphates in Ullmann s Encyclopedia of Industrial Chemistry 2008 Wiley VCH Weinheim doi 10 1002 14356007 a19 465 pub3 MSDS Archived from the original on 2017 10 28 Retrieved 2011 09 26 Sodium Phosphate Dibasic Sodium Phosphate Monobasic Oral solution Krames Patient Education Archived from the original on 2013 01 28 Retrieved 2009 10 29 External links edit nbsp Media related to Disodium phosphate at Wikimedia Commons solubility in Prophylaxis alcohol Retrieved from https en wikipedia org w index php title Disodium phosphate amp oldid 1191922498, wikipedia, wiki, book, books, library,

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