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Wikipedia

ChEBI

Chemical Entities of Biological Interest, also known as ChEBI,[1][2] is a chemical database and ontology of molecular entities focused on 'small' chemical compounds, that is part of the Open Biomedical Ontologies (OBO) effort at the European Bioinformatics Institute (EBI). The term "molecular entity" refers to any "constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity".[3] The molecular entities in question are either products of nature or synthetic products which have potential bioactivity. Molecules directly encoded by the genome, such as nucleic acids, proteins and peptides derived from proteins by proteolytic cleavage, are not as a rule included in ChEBI.

Chemical Entities of Biological Interest (ChEBI)
Content
DescriptionChemical database
Data types
captured
Small chemical compounds
Contact
Research centerEuropean Molecular Biology Laboratory
LaboratoryEuropean Bioinformatics Institute
Primary citationde Matos et al[1]
Access
Websitewww.ebi.ac.uk/chebi
Download URLftp.ebi.ac.uk/pub/databases/chebi
Web service URLwww.ebi.ac.uk/chebi/webServices.do
Sparql endpoint
Tools
Webwww.ebi.ac.uk/chebi
Miscellaneous
Data release
frequency
monthly
Curation policyManually curated

ChEBI uses nomenclature, symbolism and terminology endorsed by the International Union of Pure and Applied Chemistry (IUPAC) and nomenclature committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB).

Scope and access edit

All data in the database is non-proprietary or is derived from a non-proprietary source. It is thus freely accessible and available to anyone. In addition, each data item is fully traceable and explicitly referenced to the original source. It is related in scope other databases such as ChEMBL, ChemSpider, DrugBank, MetaboLights and PubChem.

ChEBI data is available through a public web application, web services, SPARQL endpoint and downloads.[1][2]

References edit

  1. ^ a b c de Matos P, Alcántara R, Dekker A, Ennis M, Hastings J, Haug K, Spiteri I, Turner S, Steinbeck C (2010). "Chemical Entities of Biological Interest: an update". Nucleic Acids Research. 38 (Database issue): D249-54. doi:10.1093/nar/gkp886. PMC 2808869. PMID 19854951.
  2. ^ a b Degtyarenko K, de Matos P, Ennis M, Hastings J, Zbinden M, McNaught A, Alcántara R, Darsow M, Guedj M, Ashburner M (2008). "ChEBI: a database and ontology for chemical entities of biological interest". Nucleic Acids Research. 36 (Database issue): D344-50. doi:10.1093/nar/gkm791. PMC 2238832. PMID 17932057.
  3. ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "molecular entity". doi:10.1351/goldbook.M03986

chebi, chemical, entities, biological, interest, also, known, chemical, database, ontology, molecular, entities, focused, small, chemical, compounds, that, part, open, biomedical, ontologies, effort, european, bioinformatics, institute, term, molecular, entity. Chemical Entities of Biological Interest also known as ChEBI 1 2 is a chemical database and ontology of molecular entities focused on small chemical compounds that is part of the Open Biomedical Ontologies OBO effort at the European Bioinformatics Institute EBI The term molecular entity refers to any constitutionally or isotopically distinct atom molecule ion ion pair radical radical ion complex conformer etc identifiable as a separately distinguishable entity 3 The molecular entities in question are either products of nature or synthetic products which have potential bioactivity Molecules directly encoded by the genome such as nucleic acids proteins and peptides derived from proteins by proteolytic cleavage are not as a rule included in ChEBI Chemical Entities of Biological Interest ChEBI ContentDescriptionChemical databaseData typescapturedSmall chemical compoundsContactResearch centerEuropean Molecular Biology LaboratoryLaboratoryEuropean Bioinformatics InstitutePrimary citationde Matos et al 1 AccessWebsitewww wbr ebi wbr ac wbr uk wbr chebiDownload URLftp wbr ebi wbr ac wbr uk wbr pub wbr databases wbr chebiWeb service URLwww wbr ebi wbr ac wbr uk wbr chebi wbr webServices wbr doSparql endpointBIO2RDFToolsWebwww wbr ebi wbr ac wbr uk wbr chebiMiscellaneousData releasefrequencymonthlyCuration policyManually curatedChEBI uses nomenclature symbolism and terminology endorsed by the International Union of Pure and Applied Chemistry IUPAC and nomenclature committee of the International Union of Biochemistry and Molecular Biology NC IUBMB Scope and access editAll data in the database is non proprietary or is derived from a non proprietary source It is thus freely accessible and available to anyone In addition each data item is fully traceable and explicitly referenced to the original source It is related in scope other databases such as ChEMBL ChemSpider DrugBank MetaboLights and PubChem ChEBI data is available through a public web application web services SPARQL endpoint and downloads 1 2 References edit a b c de Matos P Alcantara R Dekker A Ennis M Hastings J Haug K Spiteri I Turner S Steinbeck C 2010 Chemical Entities of Biological Interest an update Nucleic Acids Research 38 Database issue D249 54 doi 10 1093 nar gkp886 PMC 2808869 PMID 19854951 a b Degtyarenko K de Matos P Ennis M Hastings J Zbinden M McNaught A Alcantara R Darsow M Guedj M Ashburner M 2008 ChEBI a database and ontology for chemical entities of biological interest Nucleic Acids Research 36 Database issue D344 50 doi 10 1093 nar gkm791 PMC 2238832 PMID 17932057 IUPAC Compendium of Chemical Terminology 2nd ed the Gold Book 1997 Online corrected version 2006 molecular entity doi 10 1351 goldbook M03986 nbsp Wikidata has the property nbsp ChEBI ID P683 see uses Retrieved from https en wikipedia org w index php title ChEBI amp oldid 1054419966, wikipedia, wiki, book, books, library,

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