fbpx
Wikipedia

Registry of Toxic Effects of Chemical Substances

Registry of Toxic Effects of Chemical Substances (RTECS) is a database of toxicity information compiled from the open scientific literature without reference to the validity or usefulness of the studies reported. Until 2001 it was maintained by US National Institute for Occupational Safety and Health (NIOSH) as a freely available publication. It is now maintained by the private company BIOVIA[1] or from several value-added resellers and is available only for a fee or by subscription.

Contents edit

Six types of toxicity data are included in the file:

  1. Primary irritation
  2. Mutagenic effects
  3. Reproductive effects
  4. Tumorigenic effects
  5. Acute toxicity
  6. Other multiple dose toxicity

Specific numeric toxicity values such as LD50, LC50, TDLo, and TCLo are noted as well as species studied and the route of administration used. For all data the bibliographic source is listed. The studies are not evaluated in any way.

History edit

RTECS was an activity mandated by the US Congress, established by Section 20(a)(6) of the Occupational Safety and Health Act of 1970 (PL 91-596).[2] The original edition, known as the Toxic Substances List was published on June 28, 1971, and included toxicological data for approximately 5,000 chemicals. The name changed later to its current name Registry of Toxic Effects of Chemical Substances. In January 2001 the database contained 152,970 chemicals. In December 2001 RTECS was transferred from NIOSH to the private company Elsevier MDL. Symyx acquired MDL from Elsevier in 2007 and the Toxicity database was included in the acquisition. The Toxicity database is only accessible for charge on an annual subscription base.

RTECS is available in English, French and Spanish language versions, offered by the Canadian Centre for Occupational Health and Safety. The database subscription is offered on the Web, on CD-ROM and as an Intranet format. The database is also available online from NISC (National Information Services Corporation, RightAnswer.com, and ToxPlanet (Timberlake Ventures, Inc)).

References edit

  1. ^ . accelrys.com. Archived from the original on 2018-06-19. Retrieved 2018-06-19.
  2. ^ Development, Office of Research &. "REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS)". cfpub.epa.gov. Retrieved 2023-08-13.

External links edit

  • RTECS overview
  • Accelrys website 2013-10-23 at the Wayback Machine
  • RightAnswer Website
  • ToxPlanet Website

registry, toxic, effects, chemical, substances, this, article, needs, additional, citations, verification, please, help, improve, this, article, adding, citations, reliable, sources, unsourced, material, challenged, removed, find, sources, news, newspapers, bo. This article needs additional citations for verification Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources Registry of Toxic Effects of Chemical Substances news newspapers books scholar JSTOR June 2015 Learn how and when to remove this template message Registry of Toxic Effects of Chemical Substances RTECS is a database of toxicity information compiled from the open scientific literature without reference to the validity or usefulness of the studies reported Until 2001 it was maintained by US National Institute for Occupational Safety and Health NIOSH as a freely available publication It is now maintained by the private company BIOVIA 1 or from several value added resellers and is available only for a fee or by subscription Contents 1 Contents 2 History 3 References 4 External linksContents editSix types of toxicity data are included in the file Primary irritation Mutagenic effects Reproductive effects Tumorigenic effects Acute toxicity Other multiple dose toxicitySpecific numeric toxicity values such as LD50 LC50 TDLo and TCLo are noted as well as species studied and the route of administration used For all data the bibliographic source is listed The studies are not evaluated in any way History editRTECS was an activity mandated by the US Congress established by Section 20 a 6 of the Occupational Safety and Health Act of 1970 PL 91 596 2 The original edition known as the Toxic Substances List was published on June 28 1971 and included toxicological data for approximately 5 000 chemicals The name changed later to its current name Registry of Toxic Effects of Chemical Substances In January 2001 the database contained 152 970 chemicals In December 2001 RTECS was transferred from NIOSH to the private company Elsevier MDL Symyx acquired MDL from Elsevier in 2007 and the Toxicity database was included in the acquisition The Toxicity database is only accessible for charge on an annual subscription base RTECS is available in English French and Spanish language versions offered by the Canadian Centre for Occupational Health and Safety The database subscription is offered on the Web on CD ROM and as an Intranet format The database is also available online from NISC National Information Services Corporation RightAnswer com and ToxPlanet Timberlake Ventures Inc References edit BIOVIA Databases Bioactivity Databases RTECS accelrys com Archived from the original on 2018 06 19 Retrieved 2018 06 19 Development Office of Research amp REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES RTECS cfpub epa gov Retrieved 2023 08 13 External links edit nbsp Wikidata has the property nbsp RTECS number P657 see uses RTECS overview Accelrys website Archived 2013 10 23 at the Wayback Machine RightAnswer Website ToxPlanet Website Retrieved from https en wikipedia org w index php title Registry of Toxic Effects of Chemical Substances amp oldid 1195831863, wikipedia, wiki, book, books, library,

article

, read, download, free, free download, mp3, video, mp4, 3gp, jpg, jpeg, gif, png, picture, music, song, movie, book, game, games.