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Jonas Salk

Jonas Edward Salk (/sɔːlk/; born Jonas Salk; October 28, 1914 – June 23, 1995) was an American virologist and medical researcher who developed one of the first successful polio vaccines. He was born in New York City and attended the City College of New York and New York University School of Medicine.[2]

Jonas Salk
Salk in 1959
Born
Jonas Salk

(1914-10-28)October 28, 1914
DiedJune 23, 1995(1995-06-23) (aged 80)[1]
Resting placeEl Camino Memorial Park
San Diego, California
Alma materCity College of New York[1]
New York University[1]
Known forFirst polio vaccine
Spouse(s)
Donna Lindsay
(m. 1939; div. 1968)
[1]
(m. 1970)
[1]
Children3
Awards
Scientific career
FieldsMedical research,
virology, and epidemiology
InstitutionsUniversity of Pittsburgh
Salk Institute
University of Michigan
Doctoral advisorThomas Francis Jr.
Signature

In 1947, Salk accepted a professorship at the University of Pittsburgh School of Medicine, where he undertook a project beginning in 1948 to determine the number of different types of poliovirus. For the next seven years, Salk devoted himself to developing a vaccine against polio.

Salk was immediately hailed as a "miracle worker" when the vaccine's success was first made public in April 1955, and chose to not patent the vaccine or seek any profit from it in order to maximize its global distribution.[2] The National Foundation for Infantile Paralysis and the University of Pittsburgh looked into patenting the vaccine but, since Salk's techniques were not novel, their patent attorney said, "If there were any patentable novelty to be found in this phase it would lie within an extremely narrow scope and would be of doubtful value."[3][4] An immediate rush to vaccinate began in the United States and around the world. Many countries began polio immunization campaigns using Salk's vaccine, including Canada, Sweden, Denmark, Norway, West Germany, the Netherlands, Switzerland, and Belgium. By 1959, the Salk vaccine had reached about 90 countries.[5] An attenuated live oral polio vaccine was developed by Albert Sabin, coming into commercial use in 1961. Less than 25 years after the release of Salk's vaccine, domestic transmission of polio had been eliminated in the United States.

In 1963, Salk founded the Salk Institute for Biological Studies in La Jolla, California, which is today a center for medical and scientific research. He continued to conduct research and publish books in his later years, focusing in his last years on the search for a vaccine against HIV. Salk campaigned vigorously for mandatory vaccination throughout the rest of his life, calling the universal vaccination of children against disease a "moral commitment".[6] Salk's personal papers are today stored in Geisel Library at the University of California, San Diego.[7][8]

Early life and education

Jonas Salk was born in New York City to Daniel and Dora (née Press) Salk. His parents were Jewish; Daniel was born in New Jersey to immigrant parents, and Dora, who was born in Minsk, emigrated to the United States when she was twelve.[9][10] Salk's parents did not receive extensive formal education.[11] Jonas had two younger brothers, Herman and Lee, a child psychologist.[12] The family moved from East Harlem to 853 Elsmere Place in the Bronx,[13] with some time spent in Queens at 439 Beach 69th Street, Arverne.[14]

When he was 13, Salk entered Townsend Harris High School, a public school for intellectually gifted students. Named after the founder of City College of New York (CCNY), it was "a launching pad for the talented sons of immigrant parents who lacked the money—and pedigree—to attend a top private school", according to David Oshinsky, his biographer. In high school, "he was known as a perfectionist...who read everything he could lay his hands on," according to one of his fellow students.[15] Students had to cram a four-year curriculum into just three years. As a result, most dropped out or flunked out, despite the school's motto "study, study, study." Of the students who graduated, however, most had the grades to enroll in CCNY, then noted for being a highly competitive college.[16]: 96 

Education

Salk enrolled in CCNY, where he earned a Bachelor of Science degree in chemistry in 1934.[17] Oshinsky writes that "for working-class immigrant families, City College represented the apex of public higher education. Getting in was tough, but tuition was free. Competition was intense, but the rules were fairly applied. No one got an advantage based on an accident of birth."[16]

At his mother's urging, he put aside aspirations of becoming a lawyer and instead concentrated on classes necessary for admission to medical school. However, according to Oshinsky, the facilities at City College were "barely second rate." There were no research laboratories. The library was inadequate. The faculty contained few noted scholars. "What made the place special," he writes, "was the student body that had fought so hard to get there... driven by their parents.... From these ranks, of the 1930s and 1940s, emerged a wealth of intellectual talent, including more Nobel Prize winners—eight—and PhD recipients than any other public college except the University of California at Berkeley." Salk entered CCNY at the age of 15, a "common age for a freshman who had skipped multiple grades along the way."[16]: 98 

As a child, Salk did not show any interest in medicine or science in general. He said in an interview with the Academy of Achievement,[18] "As a child I was not interested in science. I was merely interested in things human, the human side of nature, if you like, and I continue to be interested in that."

Medical school

After graduating from City College of New York, Salk enrolled in New York University School of Medicine. According to Oshinsky, NYU based its modest reputation on famous alumni, such as Walter Reed, who helped conquer yellow fever. Tuition was "comparatively low, better still, it did not discriminate against Jews... while most of the surrounding medical schools—Cornell, Columbia, University of Pennsylvania, and Yale—had rigid quotas in place." Yale, for example, accepted 76 applicants in 1935 out of a pool of 501. Although 200 of the applicants were Jewish, only five got in.[16]: 98  During his years at New York University Medical School, Salk worked as a laboratory technician during the school year and as a camp counselor in the summer.[17]

During Salk's medical studies, he stood out from his peers, according to Bookchin, "not just because of his continued academic prowess—he was Alpha Omega Alpha, the Phi Beta Kappa Society of medical education—but because he had decided he did not want to practice medicine." Instead, he became absorbed in research, even taking a year off to study biochemistry. He later focused more of his studies on bacteriology, which had replaced medicine as his primary interest. He said his desire was to help humankind in general rather than single patients.[15] "It was the laboratory work, in particular, that gave new direction to his life."[16]

Salk has said, "My intention was to go to medical school, and then become a medical scientist. I did not intend to practice medicine, although in medical school, and in my internship, I did all the things that were necessary to qualify me in that regard. I had opportunities along the way to drop the idea of medicine and go into science. At one point at the end of my first year of medical school, I received an opportunity to spend a year in research and teaching in biochemistry, which I did. And at the end of that year, I was told that I could, if I wished, switch and get a Ph.D. in biochemistry, but my preference was to stay with medicine. And, I believe that this is all linked to my original ambition, or desire, which was to be of some help to humankind, so to speak, in a larger sense than just on a one-to-one basis."[19]

In his last year of medical school, Salk said, "I had an opportunity to spend time in elective periods in my last year in medical school, in a laboratory that was involved in studies on influenza. The influenza virus had just been discovered about a few years before that. And, I saw the opportunity at that time to test the question as to whether we could destroy the virus infectivity and still immunize. And so, by carefully designed experiments, we found it was possible to do so."[20]

Postgraduate research and early laboratory work

In 1941, during his postgraduate work in virology, Salk chose a two-month elective to work in the Thomas Francis' laboratory at the University of Michigan. Francis had recently joined the faculty of the medical school after working for the Rockefeller Foundation, where he had discovered the type B influenza virus. According to Bookchin, "the two-month stint in Francis's lab was Salk's first introduction to the world of virology—and he was hooked."[15]: 25  After graduating from medical school, Salk began his residency at New York's prestigious Mount Sinai Hospital, where he again worked in Francis's laboratory.[16] Salk then worked at the University of Michigan School of Public Health with Francis, on an army-commissioned project in Michigan to develop an influenza vaccine. He and Francis eventually perfected a vaccine that was soon widely used at army bases, where Salk discovered and isolated one of the strains of influenza that was included in the final vaccine.[15]: 26 

Polio research

 
President Franklin D. Roosevelt meeting with Basil O'Connor
 
Salk in 1955 at the University of Pittsburgh
 
Magazine photo of Salk to O'Neill, "the most elaborate program of its kind in history, involving 20,000 physicians and public health officers, 64,000 school personnel, and 220,000 volunteers,"[21] with over 1.8 million school children participating in the trial.[22] A 1954 Gallup poll showed that more Americans knew about the polio field trials than could give the full name of the President.
 
A March of Dimes poster, c. 1957

In 1947, Salk became ambitious for his own lab and was granted one at the University of Pittsburgh School of Medicine, but the lab was smaller than he had hoped and he found the rules imposed by the university restrictive.[23]

In 1948, Harry Weaver, the director of research at the National Foundation for Infantile Paralysis, contacted Salk. He asked Salk to find out if there were more types of polio than the three then known, offering additional space, equipment and researchers. For the first year he gathered supplies and researchers including Julius Youngner, Byron Bennett, L. James Lewis, and secretary Lorraine Friedman joined Salk's team, as well.[24][25] As time went on, Salk began securing grants from the Mellon family and was able to build a working virology laboratory.[15] He later joined the National Foundation for Infantile Paralysis's polio project established by President Franklin D. Roosevelt.[15][26]

Extensive publicity and fear of polio led to much increased funding, $67 million by 1955, but research continued on dangerous live vaccines.[21][16]: 85–87  Salk decided to use the safer 'killed' virus, instead of weakened forms of strains of polio viruses like the ones used contemporaneously by Albert Sabin, who was developing an oral vaccine.[27]

After successful tests on laboratory animals, on July 2, 1952, assisted by the staff at the D.T. Watson Home for Crippled Children, which is now the Watson Institute for International and Public Affairs in Providence, Rhode Island[28]), Salk injected 43 children with his killed-virus vaccine. A few weeks later, Salk injected children at the Polk State School for the Retarded and Feeble-minded. He vaccinated his own children in 1953.[29][30] In 1954 he tested the vaccine on about one million children, known as the polio pioneers. The vaccine was announced as safe on April 12, 1955.[21][26][31][32][33]

The project became large, involving 100 million contributors to the March of Dimes, and 7 million volunteers.[21][34]: 54  The foundation allowed itself to go into debt to finance the final research required to develop the Salk vaccine.[35] Salk worked incessantly for two-and-a-half years.[21][36]

Salk's inactivated polio vaccine came into use in 1955.[37][38] It is on the World Health Organization's List of Essential Medicines.[39][40]

Becoming a public figure

Celebrity versus privacy

 
Salk with David Ben-Gurion in Jerusalem, 1959

Salk preferred not to have his career as a scientist affected by too much personal attention, as he had always tried to remain independent and private in his research and life, but this proved to be impossible. "Young man, a great tragedy has befallen you—you've lost your anonymity", the television personality Ed Murrow said to Salk shortly after the onslaught of media attention.[41] When Murrow asked him, "Who owns this patent?", Salk replied, "Well, the people I would say. There is no patent. Could you patent the sun?"[42] The vaccine is calculated to be worth $7 billion had it been patented.[43] However, lawyers from the National Foundation for Infantile Paralysis did look into the possibility of a patent, but ultimately determined that the vaccine was not a patentable invention because of prior art.[4]

Salk served on the board of directors of the John D. and Catherine T. MacArthur Foundation.[44]

Author Jon Cohen noted, "Jonas Salk made scientists and journalists alike go goofy. As one of the only living scientists whose face was known the world over, Salk, in the public's eye, had a superstar aura. Airplane pilots would announce that he was on board, and passengers would burst into applause. Hotels routinely would upgrade him into their penthouse suites. A meal at a restaurant inevitably meant an interruption from an admirer. Scientists and journalists who regularly dealt with Salk would come to see him in more human terms, but many still initially approached him with the same drop-jawed wonder, as though some of the stardust might rub off."[45]

For the most part, however, Salk was "appalled at the demands on the public figure he has become and resentful of what he considers to be the invasion of his privacy", wrote The New York Times, a few months after his vaccine announcement.[33] The Times article noted, "at 40, the once obscure scientist ... was lifted from his laboratory almost to the level of a folk hero." He received a presidential citation, a score of awards, four honorary degrees, half a dozen foreign decorations, and letters from thousands of fellow citizens. His alma mater, City College of New York, gave him an honorary degree as Doctor of Laws. But "despite such very nice tributes", The New York Times wrote, "Salk is profoundly disturbed by the torrent of fame that has descended upon him. ... He talks continually about getting out of the limelight and back to his laboratory ... because of his genuine distaste for publicity, which he believes is inappropriate for a scientist."[33]

During a 1980 interview, 25 years later, he said, "It's as if I've been a public property ever since, having to respond to external, as well as internal, impulses. ... It's brought me enormous gratification, opened many opportunities, but at the same time placed many burdens on me. It altered my career, my relationships with colleagues; I am a public figure, no longer one of them."[41]

Maintaining his individuality

"If Salk the scientist sounds austere", wrote The New York Times, "Salk the man is a person of great warmth and tremendous enthusiasm. People who meet him generally like him." A Washington newspaper correspondent commented, "He could sell me the Brooklyn Bridge, and I never bought anything before." Award-winning geneticist Walter Nelson-Rees called him "a renaissance scientist: brilliant, sophisticated, driven ... a fantastic creature."[46]: 127 

He enjoys talking to people he likes, and "he likes a lot of people", wrote the Times. "He talks quickly, articulately, and often in complete paragraphs." And "He has very little perceptible interest in the things that interest most people—such as making money." That belongs "in the category of mink coats and Cadillacs—unnecessary", he said.[33]

Establishing the Salk Institute

 
The Salk Institute in La Jolla, California

In the years after Salk's discovery, many supporters, in particular the National Foundation, "helped him build his dream of a research complex for the investigation of biological phenomena 'from cell to society'."[47] Called the Salk Institute for Biological Studies, it opened in 1963 in the San Diego neighborhood of La Jolla, in a purpose-built facility designed by the architect Louis Kahn. Salk believed that the institution would help new and upcoming scientists along in their careers, as he said himself, "I thought how nice it would be if a place like this existed and I was invited to work there."[48]

In 1966, Salk described his "ambitious plan for the creation of a kind of Socratic academy where the supposedly alienated two cultures of science and humanism will have a favorable atmosphere for cross-fertilization."[49] Author and journalist Howard Taubman explained:

Although he is distinctly future-oriented, Dr. Salk has not lost sight of the institute's immediate aim, which is the development and use of the new biology, called molecular and cellular biology, described as part physics, part chemistry and part biology. The broad-gauged purpose of this science is to understand man's life processes.

There is talk here of the possibility, once the secret of how the cell is triggered to manufacture antibodies is discovered, that a single vaccine may be developed to protect a child against many common infectious diseases. There is speculation about the power to isolate and perhaps eliminate genetic errors that lead to birth defects.

Dr. Salk, a creative man himself, hopes that the institute will do its share in probing the wisdom of nature and thus help enlarge the wisdom of man. For the ultimate purpose of science, humanism and the arts, in his judgment, is the freeing of each individual to cultivate his full creativity, in whichever direction it leads. ... As if to prepare for Socratic encounters such as these, the institute's architect, Louis Kahn, has installed blackboards in place of concrete facings on the walls along the walks.[49]

The New York Times, in a 1980 article celebrating the 25th anniversary of the Salk vaccine, described the current workings at the facility, reporting:

At the institute, a magnificent complex of laboratories and study units set on a bluff overlooking the Pacific, Dr. Salk holds the titles of founding director and resident fellow. His own laboratory group is concerned with the immunologic aspects of cancer and the mechanisms of autoimmune disease, such as multiple sclerosis, in which the immune system attacks the body's own tissues.[41]

In an interview about his future hopes at the institute, he said, "In the end, what may have more significance is my creation of the institute and what will come out of it, because of its example as a place for excellence, a creative environment for creative minds."

Francis Crick, co-discoverer of the structure of the DNA molecule, was a leading professor at the institute until his death in 2004. The institute also served as the basis for Bruno Latour and Steve Woolgar's 1979 book Laboratory Life: The Construction of Scientific Facts.[50]

AIDS vaccine work

Beginning in the mid-1980s, Salk engaged in research to develop a vaccine for AIDS. He cofounded The Immune Response Corporation (IRC) with Kevin Kimberlin and patented Remune, an immunologic therapy, but was unable to secure liability insurance for the product.[51] The project was discontinued in 2007, twelve years after Salk's death.[citation needed]

Salk's "biophilosophy"

 
Salk during a 1988 visit at the Centers for Disease Control in Atlanta

In 1966, The New York Times referred to him as the "Father of Biophilosophy." According to Times journalist and author Howard Taubman, "he never forgets ... there is a vast amount of darkness for man to penetrate. As a biologist, he believes that his science is on the frontier of tremendous new discoveries; and as a philosopher, he is convinced that humanists and artists have joined the scientists to achieve an understanding of man in all his physical, mental and spiritual complexity. Such interchanges might lead, he would hope, to a new and important school of thinkers he would designate as biophilosophers."[49] Salk told his cousin, Joel Kassiday, at a meeting of the Congressional Clearinghouse on the Future on Capitol Hill in 1984 that he was optimistic that ways to prevent most human and animal diseases would eventually be developed. Salk said people must be prepared to take prudent risks, since "a risk-free society would become a dead-end society" without progress.

Salk describes his "biophilosophy" as the application of a "biological, evolutionary point of view to philosophical, cultural, social and psychological problems." He went into more detail in two of his books, Man Unfolding, and The Survival of the Wisest. In an interview in 1980, he described his thoughts on the subject, including his feeling that a sharp rise and an expected leveling off in the human population would take place and eventually bring a change in human attitudes:

I think of biological knowledge as providing useful analogies for understanding human nature. ... People think of biology in terms of such practical matters as drugs, but its contribution to knowledge about living systems and ourselves will in the future be equally important. ... In the past epoch, man was concerned with death, high mortality; his attitudes were antideath, antidisease", he says. "In the future, his attitudes will be expressed in terms of prolife and prohealth. The past was dominated by death control; in the future, birth control will be more important. These changes we're observing are part of a natural order and to be expected from our capacity to adapt. It's much more important to cooperate and collaborate. We are the co-authors with nature of our destiny.[41]

His definition of a "biophilosopher" is "Someone who draws upon the scriptures of nature, recognizing that we are the product of the process of evolution, and understands that we have become the process itself, through the emergence and evolution of our consciousness, our awareness, our capacity to imagine and anticipate the future, and to choose from among alternatives."[52]

Just prior to his death, Salk was working on a new book along the theme of biophilosophy, privately reported to be titled Millennium of the Mind.

Personal life and death

The day after his graduation from medical school in 1939, Salk married Donna Lindsay, a master's candidate at the New York College of Social Work. David Oshinsky writes that Donna's father, Elmer Lindsay, "a wealthy Manhattan dentist, viewed Salk as a social inferior, several cuts below Donna's former suitors." Eventually, her father agreed to the marriage on two conditions: first, Salk must wait until he could be listed as an official M.D. on the wedding invitations, and second, he must improve his "rather pedestrian status" by giving himself a middle name."[16]: 99 

They had three children: Peter, who also became a physician and a part-time professor of infectious diseases at the University of Pittsburgh;[29][30][53] Darrell, who also worked with vaccines and genetics and eventually retired from the pediatrics faculty at the University of Washington School of Medicine;[54] and Jonathan Salk. In 1968, they divorced and, in 1970, Salk married French painter Françoise Gilot.

Jonas Salk died from heart failure at the age of 80 on June 23, 1995, in La Jolla,[55] and was buried at El Camino Memorial Park in San Diego.

Honors and recognition

 
Salk's bronze bust in the Polio Hall of Fame

... in recognition of his 'historical medical' discovery ... Dr. Salk's achievement is meritorious service of the highest magnitude and dimension for the commonwealth, the country and mankind." The governor, who had three children, said that "as a parent he was 'humbly thankful to Dr. Salk,' and as Governor, 'proud to pay him tribute'.[56]

Because of Doctor Jonas E. Salk, our country is free from the cruel epidemics of poliomyelitis that once struck almost yearly. Because of his tireless work, untold hundreds of thousands who might have been crippled are sound in body today. These are Doctor Salk's true honors, and there is no way to add to them. This Medal of Freedom can only express our gratitude, and our deepest thanks.

Documentary films

  • In early 2009, the American Public Broadcasting Service aired its new documentary film, American Experience: The Polio Crusade.[24]
  • On April 12, 2010, to help celebrate the 55th anniversary of the Salk vaccine, a new 66-minute documentary, The Shot Felt 'Round the World, had its world premiere. Directed by Tjardus Greidanus[64] and produced by Laura Davis,[65] the documentary was conceived by Hollywood screenwriter and producer Carl Kurlander to bring "a fresh perspective on the era."[66]
  • In 2014, actor and director Robert Redford, who was once struck with a mild case of polio when he was a child, directed a documentary about the Salk Institute in La Jolla.[67]
  • In Chapter 10 of the 2018 season of Genius Michael McElhatton portrays Salk in a short cameo where he is on a date with Françoise Gilot.[68]

Salk's book publications

  • Man Unfolding (1972)
  • Survival of the Wisest (1973)
  • World Population and Human Values: A New Reality (1981)
  • Anatomy of Reality: Merging of Intuition and Reason (1983)

References

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  53. ^ Salk, Peter L. (January 21, 2021). "Polio vaccines brought an earlier epidemic under control. New vaccines can end this current plague". The Globe and Mail. Retrieved February 5, 2023. My father ... found himself at the forefront of research toward the development of a polio vaccine
  54. ^ "Darrell Salk relates a tale of two viruses" (Press release). University District, Seattle: University of Washington School of Medicine. February 9, 2021. Retrieved August 17, 2022.
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  56. ^ Weart, William G. "Salk is Honored by Pennsylvania" The New York Times, May 11, 1955, accessed September 14, 2015
  57. ^ Alberts, Robert C. (1986). Pitt: The Story of the University of Pittsburgh, 1787–1987. Pittsburgh, Pennsylvania: University of Pittsburgh Press. p. 263. ISBN 0-8229-1150-7. Retrieved December 7, 2009.
  58. ^ "Golden Plate Awardees of the American Academy of Achievement". www.achievement.org. American Academy of Achievement.
  59. ^ "Salk, Prof. Jonas". quirinale.it (in Italian). Retrieved December 30, 2020.
  60. ^ . Lifesciencesworld.com. Archived from the original on March 11, 2014. Retrieved July 14, 2014.
  61. ^ Salk inducted into California Hall of Fame January 10, 2008, at the Wayback Machine, California Museum.
  62. ^ CDC announces World Polio Day, CDC, October 19, 2012
  63. ^ The Guardian: Jonas Salk Google doodle, accessdate: September 14, 2015
  64. ^ "IMDb bio of director Tjardus Greidanus". IMDb. Retrieved October 28, 2014.
  65. ^ "IMDb bio of Laura Davis". IMDb. Retrieved October 28, 2014.
  66. ^ "Film reveals Pittsburgh's polio stories" Pittsburgh Post-Gazette, April 14, 2010
  67. ^ Bell, Diane (June 30, 2014). "Director Robert Redford gives sneak preview in La Jolla of his Salk Institute documentary film". The San Diego Union-Tribune. Retrieved April 29, 2020.
  68. ^ "Picasso: Chapter 10". IMDb.

Further reading

  • Jacobs, Charlotte DeCroes. Jonas Salk: A Life, Oxford Univ. Press (2015), scholarly biography
  • Kluger, Jeffrey. Splendid Solution: Jonas Salk and the Conquest of Polio, Berkley Books (2006), history of the polio vaccine
  • Weintraub, B. "Jonas Salk (1914–1995) and the first vacccine against polio." Israel Chemist and Engineer. July 2020, iss. 6. p31-34 [1]

External links

  • The American Experience: The Polio Crusade video, 1 hr. by PBS
  • "Legacy of Salk Institute", video, 30 minutes, history of Salk vaccine
  • "Polio Vaccine" intro., Britannica, video, 1 minute
  • Jonas Salk Legacy Foundation
  • Jonas Salk Trust
  • Documents regarding Jonas Salk and the Salk Polio Vaccine, Dwight D. Eisenhower Presidential Library
  • 1985 Open Mind interview with Richard D. Heffner: Man Evolving...
  • Pittsburgh Post-Gazette feature on Jonas Salk and the Polio cure 50 years later
  • The Salk School of Science (New York, New York)
  • Patent US Patent 5,256,767 : Vaccine against HIV
  • The short film Man Evolving (1985) is available for free download at the Internet Archive.
  • Register of Jonas Salk Papers, 1926–1991 – MSS 1, held in the UC San Diego Library's Special Collections & Archives

jonas, salk, salk, redirects, here, other, uses, salk, disambiguation, jonas, edward, salk, ɔː, born, october, 1914, june, 1995, american, virologist, medical, researcher, developed, first, successful, polio, vaccines, born, york, city, attended, city, college. Salk redirects here For other uses see Salk disambiguation Jonas Edward Salk s ɔː l k born Jonas Salk October 28 1914 June 23 1995 was an American virologist and medical researcher who developed one of the first successful polio vaccines He was born in New York City and attended the City College of New York and New York University School of Medicine 2 Jonas SalkSalk in 1959BornJonas Salk 1914 10 28 October 28 1914New York City U S DiedJune 23 1995 1995 06 23 aged 80 1 La Jolla California U S 1 Resting placeEl Camino Memorial ParkSan Diego CaliforniaAlma materCity College of New York 1 New York University 1 Known forFirst polio vaccineSpouse s Donna Lindsay m 1939 div 1968 wbr 1 Francoise Gilot m 1970 wbr 1 Children3AwardsAlbert Lasker Award 1956 1 Robert Koch Medal 1 Mellon Institute Award 1 United States Presidential Citation 1 Congressional Gold Medal 1975 1 Presidential Medal of Freedom 1977 Scientific careerFieldsMedical research virology and epidemiologyInstitutionsUniversity of PittsburghSalk InstituteUniversity of MichiganDoctoral advisorThomas Francis Jr SignatureIn 1947 Salk accepted a professorship at the University of Pittsburgh School of Medicine where he undertook a project beginning in 1948 to determine the number of different types of poliovirus For the next seven years Salk devoted himself to developing a vaccine against polio Salk was immediately hailed as a miracle worker when the vaccine s success was first made public in April 1955 and chose to not patent the vaccine or seek any profit from it in order to maximize its global distribution 2 The National Foundation for Infantile Paralysis and the University of Pittsburgh looked into patenting the vaccine but since Salk s techniques were not novel their patent attorney said If there were any patentable novelty to be found in this phase it would lie within an extremely narrow scope and would be of doubtful value 3 4 An immediate rush to vaccinate began in the United States and around the world Many countries began polio immunization campaigns using Salk s vaccine including Canada Sweden Denmark Norway West Germany the Netherlands Switzerland and Belgium By 1959 the Salk vaccine had reached about 90 countries 5 An attenuated live oral polio vaccine was developed by Albert Sabin coming into commercial use in 1961 Less than 25 years after the release of Salk s vaccine domestic transmission of polio had been eliminated in the United States In 1963 Salk founded the Salk Institute for Biological Studies in La Jolla California which is today a center for medical and scientific research He continued to conduct research and publish books in his later years focusing in his last years on the search for a vaccine against HIV Salk campaigned vigorously for mandatory vaccination throughout the rest of his life calling the universal vaccination of children against disease a moral commitment 6 Salk s personal papers are today stored in Geisel Library at the University of California San Diego 7 8 Contents 1 Early life and education 1 1 Education 1 2 Medical school 1 3 Postgraduate research and early laboratory work 2 Polio research 3 Becoming a public figure 3 1 Celebrity versus privacy 3 2 Maintaining his individuality 4 Establishing the Salk Institute 5 AIDS vaccine work 6 Salk s biophilosophy 7 Personal life and death 8 Honors and recognition 8 1 Documentary films 9 Salk s book publications 10 References 11 Further reading 12 External linksEarly life and education EditJonas Salk was born in New York City to Daniel and Dora nee Press Salk His parents were Jewish Daniel was born in New Jersey to immigrant parents and Dora who was born in Minsk emigrated to the United States when she was twelve 9 10 Salk s parents did not receive extensive formal education 11 Jonas had two younger brothers Herman and Lee a child psychologist 12 The family moved from East Harlem to 853 Elsmere Place in the Bronx 13 with some time spent in Queens at 439 Beach 69th Street Arverne 14 When he was 13 Salk entered Townsend Harris High School a public school for intellectually gifted students Named after the founder of City College of New York CCNY it was a launching pad for the talented sons of immigrant parents who lacked the money and pedigree to attend a top private school according to David Oshinsky his biographer In high school he was known as a perfectionist who read everything he could lay his hands on according to one of his fellow students 15 Students had to cram a four year curriculum into just three years As a result most dropped out or flunked out despite the school s motto study study study Of the students who graduated however most had the grades to enroll in CCNY then noted for being a highly competitive college 16 96 Education Edit Salk enrolled in CCNY where he earned a Bachelor of Science degree in chemistry in 1934 17 Oshinsky writes that for working class immigrant families City College represented the apex of public higher education Getting in was tough but tuition was free Competition was intense but the rules were fairly applied No one got an advantage based on an accident of birth 16 At his mother s urging he put aside aspirations of becoming a lawyer and instead concentrated on classes necessary for admission to medical school However according to Oshinsky the facilities at City College were barely second rate There were no research laboratories The library was inadequate The faculty contained few noted scholars What made the place special he writes was the student body that had fought so hard to get there driven by their parents From these ranks of the 1930s and 1940s emerged a wealth of intellectual talent including more Nobel Prize winners eight and PhD recipients than any other public college except the University of California at Berkeley Salk entered CCNY at the age of 15 a common age for a freshman who had skipped multiple grades along the way 16 98 As a child Salk did not show any interest in medicine or science in general He said in an interview with the Academy of Achievement 18 As a child I was not interested in science I was merely interested in things human the human side of nature if you like and I continue to be interested in that Medical school Edit After graduating from City College of New York Salk enrolled in New York University School of Medicine According to Oshinsky NYU based its modest reputation on famous alumni such as Walter Reed who helped conquer yellow fever Tuition was comparatively low better still it did not discriminate against Jews while most of the surrounding medical schools Cornell Columbia University of Pennsylvania and Yale had rigid quotas in place Yale for example accepted 76 applicants in 1935 out of a pool of 501 Although 200 of the applicants were Jewish only five got in 16 98 During his years at New York University Medical School Salk worked as a laboratory technician during the school year and as a camp counselor in the summer 17 During Salk s medical studies he stood out from his peers according to Bookchin not just because of his continued academic prowess he was Alpha Omega Alpha the Phi Beta Kappa Society of medical education but because he had decided he did not want to practice medicine Instead he became absorbed in research even taking a year off to study biochemistry He later focused more of his studies on bacteriology which had replaced medicine as his primary interest He said his desire was to help humankind in general rather than single patients 15 It was the laboratory work in particular that gave new direction to his life 16 Salk has said My intention was to go to medical school and then become a medical scientist I did not intend to practice medicine although in medical school and in my internship I did all the things that were necessary to qualify me in that regard I had opportunities along the way to drop the idea of medicine and go into science At one point at the end of my first year of medical school I received an opportunity to spend a year in research and teaching in biochemistry which I did And at the end of that year I was told that I could if I wished switch and get a Ph D in biochemistry but my preference was to stay with medicine And I believe that this is all linked to my original ambition or desire which was to be of some help to humankind so to speak in a larger sense than just on a one to one basis 19 In his last year of medical school Salk said I had an opportunity to spend time in elective periods in my last year in medical school in a laboratory that was involved in studies on influenza The influenza virus had just been discovered about a few years before that And I saw the opportunity at that time to test the question as to whether we could destroy the virus infectivity and still immunize And so by carefully designed experiments we found it was possible to do so 20 Postgraduate research and early laboratory work Edit In 1941 during his postgraduate work in virology Salk chose a two month elective to work in the Thomas Francis laboratory at the University of Michigan Francis had recently joined the faculty of the medical school after working for the Rockefeller Foundation where he had discovered the type B influenza virus According to Bookchin the two month stint in Francis s lab was Salk s first introduction to the world of virology and he was hooked 15 25 After graduating from medical school Salk began his residency at New York s prestigious Mount Sinai Hospital where he again worked in Francis s laboratory 16 Salk then worked at the University of Michigan School of Public Health with Francis on an army commissioned project in Michigan to develop an influenza vaccine He and Francis eventually perfected a vaccine that was soon widely used at army bases where Salk discovered and isolated one of the strains of influenza that was included in the final vaccine 15 26 Polio research EditFurther information Polio and Polio vaccine President Franklin D Roosevelt meeting with Basil O Connor Salk in 1955 at the University of Pittsburgh Magazine photo of Salk to O Neill the most elaborate program of its kind in history involving 20 000 physicians and public health officers 64 000 school personnel and 220 000 volunteers 21 with over 1 8 million school children participating in the trial 22 A 1954 Gallup poll showed that more Americans knew about the polio field trials than could give the full name of the President A March of Dimes poster c 1957 In 1947 Salk became ambitious for his own lab and was granted one at the University of Pittsburgh School of Medicine but the lab was smaller than he had hoped and he found the rules imposed by the university restrictive 23 In 1948 Harry Weaver the director of research at the National Foundation for Infantile Paralysis contacted Salk He asked Salk to find out if there were more types of polio than the three then known offering additional space equipment and researchers For the first year he gathered supplies and researchers including Julius Youngner Byron Bennett L James Lewis and secretary Lorraine Friedman joined Salk s team as well 24 25 As time went on Salk began securing grants from the Mellon family and was able to build a working virology laboratory 15 He later joined the National Foundation for Infantile Paralysis s polio project established by President Franklin D Roosevelt 15 26 Extensive publicity and fear of polio led to much increased funding 67 million by 1955 but research continued on dangerous live vaccines 21 16 85 87 Salk decided to use the safer killed virus instead of weakened forms of strains of polio viruses like the ones used contemporaneously by Albert Sabin who was developing an oral vaccine 27 After successful tests on laboratory animals on July 2 1952 assisted by the staff at the D T Watson Home for Crippled Children which is now the Watson Institute for International and Public Affairs in Providence Rhode Island 28 Salk injected 43 children with his killed virus vaccine A few weeks later Salk injected children at the Polk State School for the Retarded and Feeble minded He vaccinated his own children in 1953 29 30 In 1954 he tested the vaccine on about one million children known as the polio pioneers The vaccine was announced as safe on April 12 1955 21 26 31 32 33 The project became large involving 100 million contributors to the March of Dimes and 7 million volunteers 21 34 54 The foundation allowed itself to go into debt to finance the final research required to develop the Salk vaccine 35 Salk worked incessantly for two and a half years 21 36 Salk s inactivated polio vaccine came into use in 1955 37 38 It is on the World Health Organization s List of Essential Medicines 39 40 Becoming a public figure EditCelebrity versus privacy Edit Salk with David Ben Gurion in Jerusalem 1959 Salk preferred not to have his career as a scientist affected by too much personal attention as he had always tried to remain independent and private in his research and life but this proved to be impossible Young man a great tragedy has befallen you you ve lost your anonymity the television personality Ed Murrow said to Salk shortly after the onslaught of media attention 41 When Murrow asked him Who owns this patent Salk replied Well the people I would say There is no patent Could you patent the sun 42 The vaccine is calculated to be worth 7 billion had it been patented 43 However lawyers from the National Foundation for Infantile Paralysis did look into the possibility of a patent but ultimately determined that the vaccine was not a patentable invention because of prior art 4 Salk served on the board of directors of the John D and Catherine T MacArthur Foundation 44 Author Jon Cohen noted Jonas Salk made scientists and journalists alike go goofy As one of the only living scientists whose face was known the world over Salk in the public s eye had a superstar aura Airplane pilots would announce that he was on board and passengers would burst into applause Hotels routinely would upgrade him into their penthouse suites A meal at a restaurant inevitably meant an interruption from an admirer Scientists and journalists who regularly dealt with Salk would come to see him in more human terms but many still initially approached him with the same drop jawed wonder as though some of the stardust might rub off 45 For the most part however Salk was appalled at the demands on the public figure he has become and resentful of what he considers to be the invasion of his privacy wrote The New York Times a few months after his vaccine announcement 33 The Times article noted at 40 the once obscure scientist was lifted from his laboratory almost to the level of a folk hero He received a presidential citation a score of awards four honorary degrees half a dozen foreign decorations and letters from thousands of fellow citizens His alma mater City College of New York gave him an honorary degree as Doctor of Laws But despite such very nice tributes The New York Times wrote Salk is profoundly disturbed by the torrent of fame that has descended upon him He talks continually about getting out of the limelight and back to his laboratory because of his genuine distaste for publicity which he believes is inappropriate for a scientist 33 During a 1980 interview 25 years later he said It s as if I ve been a public property ever since having to respond to external as well as internal impulses It s brought me enormous gratification opened many opportunities but at the same time placed many burdens on me It altered my career my relationships with colleagues I am a public figure no longer one of them 41 Maintaining his individuality Edit If Salk the scientist sounds austere wrote The New York Times Salk the man is a person of great warmth and tremendous enthusiasm People who meet him generally like him A Washington newspaper correspondent commented He could sell me the Brooklyn Bridge and I never bought anything before Award winning geneticist Walter Nelson Rees called him a renaissance scientist brilliant sophisticated driven a fantastic creature 46 127 He enjoys talking to people he likes and he likes a lot of people wrote the Times He talks quickly articulately and often in complete paragraphs And He has very little perceptible interest in the things that interest most people such as making money That belongs in the category of mink coats and Cadillacs unnecessary he said 33 Establishing the Salk Institute Edit The Salk Institute in La Jolla California In the years after Salk s discovery many supporters in particular the National Foundation helped him build his dream of a research complex for the investigation of biological phenomena from cell to society 47 Called the Salk Institute for Biological Studies it opened in 1963 in the San Diego neighborhood of La Jolla in a purpose built facility designed by the architect Louis Kahn Salk believed that the institution would help new and upcoming scientists along in their careers as he said himself I thought how nice it would be if a place like this existed and I was invited to work there 48 In 1966 Salk described his ambitious plan for the creation of a kind of Socratic academy where the supposedly alienated two cultures of science and humanism will have a favorable atmosphere for cross fertilization 49 Author and journalist Howard Taubman explained Although he is distinctly future oriented Dr Salk has not lost sight of the institute s immediate aim which is the development and use of the new biology called molecular and cellular biology described as part physics part chemistry and part biology The broad gauged purpose of this science is to understand man s life processes There is talk here of the possibility once the secret of how the cell is triggered to manufacture antibodies is discovered that a single vaccine may be developed to protect a child against many common infectious diseases There is speculation about the power to isolate and perhaps eliminate genetic errors that lead to birth defects Dr Salk a creative man himself hopes that the institute will do its share in probing the wisdom of nature and thus help enlarge the wisdom of man For the ultimate purpose of science humanism and the arts in his judgment is the freeing of each individual to cultivate his full creativity in whichever direction it leads As if to prepare for Socratic encounters such as these the institute s architect Louis Kahn has installed blackboards in place of concrete facings on the walls along the walks 49 The New York Times in a 1980 article celebrating the 25th anniversary of the Salk vaccine described the current workings at the facility reporting At the institute a magnificent complex of laboratories and study units set on a bluff overlooking the Pacific Dr Salk holds the titles of founding director and resident fellow His own laboratory group is concerned with the immunologic aspects of cancer and the mechanisms of autoimmune disease such as multiple sclerosis in which the immune system attacks the body s own tissues 41 In an interview about his future hopes at the institute he said In the end what may have more significance is my creation of the institute and what will come out of it because of its example as a place for excellence a creative environment for creative minds Francis Crick co discoverer of the structure of the DNA molecule was a leading professor at the institute until his death in 2004 The institute also served as the basis for Bruno Latour and Steve Woolgar s 1979 book Laboratory Life The Construction of Scientific Facts 50 AIDS vaccine work EditBeginning in the mid 1980s Salk engaged in research to develop a vaccine for AIDS He cofounded The Immune Response Corporation IRC with Kevin Kimberlin and patented Remune an immunologic therapy but was unable to secure liability insurance for the product 51 The project was discontinued in 2007 twelve years after Salk s death citation needed Salk s biophilosophy Edit Salk during a 1988 visit at the Centers for Disease Control in Atlanta In 1966 The New York Times referred to him as the Father of Biophilosophy According to Times journalist and author Howard Taubman he never forgets there is a vast amount of darkness for man to penetrate As a biologist he believes that his science is on the frontier of tremendous new discoveries and as a philosopher he is convinced that humanists and artists have joined the scientists to achieve an understanding of man in all his physical mental and spiritual complexity Such interchanges might lead he would hope to a new and important school of thinkers he would designate as biophilosophers 49 Salk told his cousin Joel Kassiday at a meeting of the Congressional Clearinghouse on the Future on Capitol Hill in 1984 that he was optimistic that ways to prevent most human and animal diseases would eventually be developed Salk said people must be prepared to take prudent risks since a risk free society would become a dead end society without progress Salk describes his biophilosophy as the application of a biological evolutionary point of view to philosophical cultural social and psychological problems He went into more detail in two of his books Man Unfolding and The Survival of the Wisest In an interview in 1980 he described his thoughts on the subject including his feeling that a sharp rise and an expected leveling off in the human population would take place and eventually bring a change in human attitudes I think of biological knowledge as providing useful analogies for understanding human nature People think of biology in terms of such practical matters as drugs but its contribution to knowledge about living systems and ourselves will in the future be equally important In the past epoch man was concerned with death high mortality his attitudes were antideath antidisease he says In the future his attitudes will be expressed in terms of prolife and prohealth The past was dominated by death control in the future birth control will be more important These changes we re observing are part of a natural order and to be expected from our capacity to adapt It s much more important to cooperate and collaborate We are the co authors with nature of our destiny 41 His definition of a biophilosopher is Someone who draws upon the scriptures of nature recognizing that we are the product of the process of evolution and understands that we have become the process itself through the emergence and evolution of our consciousness our awareness our capacity to imagine and anticipate the future and to choose from among alternatives 52 Just prior to his death Salk was working on a new book along the theme of biophilosophy privately reported to be titled Millennium of the Mind Personal life and death EditThe day after his graduation from medical school in 1939 Salk married Donna Lindsay a master s candidate at the New York College of Social Work David Oshinsky writes that Donna s father Elmer Lindsay a wealthy Manhattan dentist viewed Salk as a social inferior several cuts below Donna s former suitors Eventually her father agreed to the marriage on two conditions first Salk must wait until he could be listed as an official M D on the wedding invitations and second he must improve his rather pedestrian status by giving himself a middle name 16 99 They had three children Peter who also became a physician and a part time professor of infectious diseases at the University of Pittsburgh 29 30 53 Darrell who also worked with vaccines and genetics and eventually retired from the pediatrics faculty at the University of Washington School of Medicine 54 and Jonathan Salk In 1968 they divorced and in 1970 Salk married French painter Francoise Gilot Jonas Salk died from heart failure at the age of 80 on June 23 1995 in La Jolla 55 and was buried at El Camino Memorial Park in San Diego Honors and recognition Edit Salk s bronze bust in the Polio Hall of Fame 1955 one month after the vaccine announcement he was honored by the Commonwealth of Pennsylvania where he was given their highest award for services by Governor George M Leader Meritorious Service Medal where the governor added in recognition of his historical medical discovery Dr Salk s achievement is meritorious service of the highest magnitude and dimension for the commonwealth the country and mankind The governor who had three children said that as a parent he was humbly thankful to Dr Salk and as Governor proud to pay him tribute 56 1955 City University of New York creates the Salk Scholarship fund which it awards to multiple outstanding pre med students each year 1956 awarded the Lasker Award 1957 the Municipal Hospital building where Salk conducted his polio research at the University of Pittsburgh is renamed Jonas Salk Hall and is home to the university s School of Pharmacy and Dentistry 57 1958 awarded the James D Bruce Memorial Award 1958 elected to the Polio Hall of Fame which was dedicated in Warm Springs Georgia 1975 awarded the Jawaharlal Nehru Award and the Congressional Gold Medal 1976 awarded the Academy of Achievement s Golden Plate Award 58 1976 named the Humanist of the Year by the American Humanist Association 1977 awarded the Presidential Medal of Freedom from President Jimmy Carter with the following statement accompanying the medal Because of Doctor Jonas E Salk our country is free from the cruel epidemics of poliomyelitis that once struck almost yearly Because of his tireless work untold hundreds of thousands who might have been crippled are sound in body today These are Doctor Salk s true honors and there is no way to add to them This Medal of Freedom can only express our gratitude and our deepest thanks 1981 decorated by the Italian government on January 3 as a Grand Officer of the Order of Merit of the Italian Republic 59 1996 the March of Dimes Foundation created an annual 250 000 cash Prize to outstanding biologists as a tribute to Salk 60 2006 the United States Postal Service issued a 63 cent Distinguished Americans series postage stamp in his honor 2007 California Governor Arnold Schwarzenegger and First Lady Maria Shriver inducted Salk into the California Hall of Fame 61 2009 BBYO boys chapter chartered in his honor in Scottsdale Arizona Named Jonas Salk AZA 2357 Schools in Mesa Arizona Spokane Washington Tulsa Oklahoma Bolingbrook Illinois Levittown New York Old Bridge New Jersey Merrillville Indiana Sacramento California and Mira Mesa California are named after him 2012 October 24 in honor of his birthday has been named World Polio Day and was originated by Rotary International over a decade earlier 62 2014 On the 100th anniversary of Salk s birth a Google Doodle was created to honor the physician and medical researcher The doodle shows happy and healthy children and adults playing and going about their lives with two children hold up a sign saying Thank you Dr Salk 3 63 Documentary films Edit In early 2009 the American Public Broadcasting Service aired its new documentary film American Experience The Polio Crusade 24 On April 12 2010 to help celebrate the 55th anniversary of the Salk vaccine a new 66 minute documentary The Shot Felt Round the World had its world premiere Directed by Tjardus Greidanus 64 and produced by Laura Davis 65 the documentary was conceived by Hollywood screenwriter and producer Carl Kurlander to bring a fresh perspective on the era 66 In 2014 actor and director Robert Redford who was once struck with a mild case of polio when he was a child directed a documentary about the Salk Institute in La Jolla 67 In Chapter 10 of the 2018 season of Genius Michael McElhatton portrays Salk in a short cameo where he is on a date with Francoise Gilot 68 Salk s book publications EditMan Unfolding 1972 Survival of the Wisest 1973 World Population and Human Values A New Reality 1981 Anatomy of Reality Merging of Intuition and Reason 1983 References Edit a b c d e f g h i j k Dr Jonas Salk Whose Vaccine Turned Tide on Polio Dies at 80 The New York Times June 24 1995 Retrieved October 23 2020 a b About Jonas Salk Salk Institute for Biological Studies Salk Institute for Biological Studies Retrieved February 22 2016 a b Hiltzik Michael October 28 2014 On Jonas Salk s 100th birthday a celebration of his polio vaccine Los Angeles Times Retrieved October 28 2014 a b The Real Reason Why Salk Refused to Patent the Polio Vaccine Biotech now org Retrieved July 14 2014 Tan Siang Yong Ponstein Nate January 2019 Jonas Salk 1914 1995 A vaccine against polio Singapore Medical Journal 60 1 9 10 doi 10 11622 smedj 2019002 ISSN 0037 5675 PMC 6351694 PMID 30840995 Jacobs Charlotte DeCroes Vaccinations have always been controversial in America Column USA Today August 4 2015 UC San Diego Library Receives Personal Papers of Jonas Salk Newswise March 20 2014 San Diego Union Tribune 20 March 2014 UCSD to house Salk s papers accessed July 3 2015 Selected Questions from Student Interviews Darrell Salk M D The Jonas Salk Center 2001 Retrieved April 15 2020 Charlotte DeCroes Jacobs April 21 2015 Jonas Salk A Life Oxford University Press pp 45 ISBN 978 0 19 933443 8 Jonas Edward Salk facts information pictures Encyclopedia com articles about Jonas Edward Salk www encyclopedia com Dr Lee Salk Child Psychologist And Popular Author Dies at 65 New York Times Retrieved August 15 2011 Roberts Sam July 27 2012 New York Census Data Centuries Old Is Now Online City College of New York Microcosm Yearbook 1934 a b c d e f Bookchin Debbie and Schumacher Jim The Virus and the Vaccine Macmillan 2004 ISBN 0 312 34272 1 a b c d e f g h Oshinsky David M 2005 Polio An American Story Oxford Oxford University Press ISBN 978 0 19 515294 4 OCLC 1031748949 a b Sherrow Victoria Jonas Salk Revised Edition 2009 p 12 Jonas Salk Biography and Interview www achievement org American Academy of Achievement Jonas Salk Biography and Interview www achievement org American Academy of Achievement Jonas Salk Interview page 2 8 Academy of Achievement Archived from the original on July 22 2015 Retrieved August 14 2015 a b c d e O Neill William L 1989 American High The Years of Confidence 1945 1960 New York Simon and Schuster ISBN 0 02 923679 7 Rose DR 2004 Fact Sheet Polio Vaccine Field Trial of 1954 March of Dimes Archives 2004 02 11 Bankston John 2002 Jonas Salk and the Polio Vaccine Bear Delaware Mitchell Lane Publishers pp 30 32 a b American Experience The Polio Crusade Los Angeles Times Television Review February 2 2009 McPherson Stephanie 2002 Jonas Salk Conquering Polio Minneapolis Minnesota Lerner Publications Company pp 33 37 ISBN 9780822549642 a b Wisdom magazine August 1956 pp 6 15 Jonas Salk and Albert Bruce Sabin Science History Institute January 8 2017 Retrieved June 15 2020 The Watson Institute special education history The Watson Institute Retrieved November 11 2021 a b Among The 1st To Get A Polio Vaccine Peter Salk Says Don t Rush A COVID 19 Shot NPR May 30 2020 Retrieved December 26 2020 a b From Polio To The COVID Vaccine Dr Peter Salk Sees Great Progress NPR December 26 2020 Retrieved December 26 2020 Complete Program Transcript The Polio Crusade WGBH American Experience PBS Retrieved July 14 2014 Anti polio Vaccine Guaranteed by Salk The New York Times November 13 1953 a b c d What Price Fame to Dr Salk The New York Times July 17 1955 Offit Paul 2005 The Cutter incident 50 years later PDF N Engl J Med 352 14 1411 1412 doi 10 1056 NEJMp048180 PMID 15814877 Fleischer Doris Z The Disability Rights Movement From Charity to Confrontation Temple University Press 2001 Denenberg Dennis and Roscoe Lorraine 50 American Heroes Every Kid Should Meet Millbrook Press 2006 Polio vaccines WHO position paper March 2016 PDF Wkly Epidemiol Rec 91 12 145 168 March 25 2016 PMID 27039410 Archived PDF from the original on June 3 2016 Bazin H 2011 Vaccination A History John Libbey Eurotext p 395 ISBN 9782742007752 Archived from the original on September 8 2017 World Health Organization 2019 World Health Organization model list of essential medicines 21st list 2019 Geneva World Health Organization hdl 10665 325771 WHO MVP EMP IAU 2019 06 License CC BY NC SA 3 0 IGO World Health Organization 2021 World Health Organization model list of essential medicines 22nd list 2021 Geneva World Health Organization hdl 10665 345533 WHO MHP HPS EML 2021 02 a b c d Glueck Grace Salk Studies Man s Future The New York Times April 8 1980 Smith Jane S 1990 Patenting the Sun Polio and The Salk Vaccine New York William Morrow ISBN 0 688 09494 5 How Much Money Did Jonas Salk Potentially Forfeit By Not Patenting The Polio Vaccine Forbes August 8 2012 Retrieved September 30 2014 Sherrow Victoria 2009 Jonas Salk Revised Edition Infobase Publishing p 99 ISBN 9781438104119 Cohen Jon 2001 Shots in the Dark The Wayward Search for an AIDS Vaccine New York W W Norton amp Co p 88 ISBN 0 393 05027 0 Gold Michael A Conspiracy of Cells State Univ of NY Press 1985 Salk 25 years after vaccine Detroit Free Press April 9 1980 p 31 Johnson George November 25 1990 Once Again A MAN WITH A MISSION The New York Times Retrieved October 13 2021 a b c Taubman Howard Father of Biophilosophy The New York Times November 11 1966 Latour Bruno Woolgar Steve September 21 1986 Laboratory Life Princeton University Press ISBN 9780691028323 Retrieved May 4 2017 Remune HIV 1 Immunogen Salk vaccine Archived March 21 2009 at the Wayback Machine AIDSmeds com Man Evolving video interview 1985 28 minutes Salk Peter L January 21 2021 Polio vaccines brought an earlier epidemic under control New vaccines can end this current plague The Globe and Mail Retrieved February 5 2023 My father found himself at the forefront of research toward the development of a polio vaccine Darrell Salk relates a tale of two viruses Press release University District Seattle University of Washington School of Medicine February 9 2021 Retrieved August 17 2022 The New York Times Dr Jonas Salk Whose Vaccine Turned Tide on Polio Dies at 80 June 25 1995 Retrieved July 15 2010 Weart William G Salk is Honored by Pennsylvania The New York Times May 11 1955 accessed September 14 2015 Alberts Robert C 1986 Pitt The Story of the University of Pittsburgh 1787 1987 Pittsburgh Pennsylvania University of Pittsburgh Press p 263 ISBN 0 8229 1150 7 Retrieved December 7 2009 Golden Plate Awardees of the American Academy of Achievement www achievement org American Academy of Achievement Salk Prof Jonas quirinale it in Italian Retrieved December 30 2020 March of Dimes Awards 250 000 Prize to Scientists Unraveling the Causes of Muscular Dystrophy Lifesciencesworld com Archived from the original on March 11 2014 Retrieved July 14 2014 Salk inducted into California Hall of Fame Archived January 10 2008 at the Wayback Machine California Museum CDC announces World Polio Day CDC October 19 2012 The Guardian Jonas Salk Google doodle accessdate September 14 2015 IMDb bio of director Tjardus Greidanus IMDb Retrieved October 28 2014 IMDb bio of Laura Davis IMDb Retrieved October 28 2014 Film reveals Pittsburgh s polio stories Pittsburgh Post Gazette April 14 2010 Bell Diane June 30 2014 Director Robert Redford gives sneak preview in La Jolla of his Salk Institute documentary film The San Diego Union Tribune Retrieved April 29 2020 Picasso Chapter 10 IMDb Further reading EditJacobs Charlotte DeCroes Jonas Salk A Life Oxford Univ Press 2015 scholarly biography Kluger Jeffrey Splendid Solution Jonas Salk and the Conquest of Polio Berkley Books 2006 history of the polio vaccine Weintraub B Jonas Salk 1914 1995 and the first vacccine against polio Israel Chemist and Engineer July 2020 iss 6 p31 34 1 External links Edit Wikimedia Commons has media related to Jonas Salk Wikiquote has quotations related to Jonas Salk The American Experience The Polio Crusade video 1 hr by PBS Legacy of Salk Institute video 30 minutes history of Salk vaccine Polio Vaccine intro Britannica video 1 minute Jonas Salk Legacy Foundation Jonas Salk Trust Salk Institute for Biological Studies Documents regarding Jonas Salk and the Salk Polio Vaccine Dwight D Eisenhower Presidential Library 1985 Open Mind interview with Richard D Heffner Man Evolving Pittsburgh Post Gazette feature on Jonas Salk and the Polio cure 50 years later The Salk School of Science New York New York Patent US Patent 5 256 767 Vaccine against HIV The short film Man Evolving 1985 is available for free download at the Internet Archive Register of Jonas Salk Papers 1926 1991 MSS 1 held in the UC San Diego Library s Special Collections amp Archives Portals Biography Medicine Viruses Retrieved from https en wikipedia org w index php title Jonas Salk amp oldid 1146658000, wikipedia, wiki, book, books, library,

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