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S-Nitroso-N-acetylpenicillamine

S-Nitroso-N-acetylpenicillamine (SNAP) is the organosulfur compound with the formula ONSC(CH3)2CH(NHAc)CO2H. It is a green solid.[2]

S-Nitroso-N-acetylpenicillamine
Names
IUPAC name
S-Nitroso-N-acetylpenicillamine
Other names
N-Acetyl-3-(nitrosothio)-DL-valine
S-Nitroso-N-acetylpenicillamine
Identifiers
  • 79032-48-7 Y
3D model (JSmol)
  • Interactive image
Abbreviations SNAP
ChEBI
  • CHEBI:77702 Y
ChEMBL
  • ChEMBL73188 Y
ChemSpider
  • 5036251 Y
  • 6603945
UNII
  • 6E47VKF8B8 Y
  • DTXSID80897531
  • InChI=1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1 Y
    Key: ZIIQCSMRQKCOCT-YFKPBYRVSA-N Y
  • InChI=1/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1
    Key: ZIIQCSMRQKCOCT-YFKPBYRVBE
  • O=C(N[C@@H](C(=O)O)C(SN=O)(C)C)C
Properties
C7H12N2O4S
Molar mass 220.25 g/mol
Appearance green solid
Hazards
GHS labelling:[1]
Warning
H315, H319, H335
P261, P264, P271, P280, P302+P352, P305+P351+P338
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)

SNAP is an S-nitrosothiol and is used as a model for the general class of S-nitrosothiols which have received much attention in biochemistry because nitric oxide and some organic nitroso derivatives serve as signaling molecules in living systems, especially related to vasodilation.[3] SNAP is derived from the amino acid penicillamine. S-Nitrosoglutathione is a related agent.

References edit

  1. ^ "N3398 h S-Nitroso-N-acetyl-DL-penicillamine". Sigma-Aldric. Retrieved 13 December 2021.
  2. ^ Arulsamy, N.; Bohle, D. S.; Butt, J. A.; Irvine, G. J.; Jordan, P. A.; Sagan, E. (1999). "Interrelationships between Conformational Dynamics and the Redox Chemistry of S-Nitrosothiols". Journal of the American Chemical Society. 121 (30): 7115–7123. doi:10.1021/ja9901314.
  3. ^ Zhang Y.; Hogg, N. (2005). "S-Nitrosothiols: Cellular Formation and Transport". Free Radical Biology and Medicine. 38 (7): 831–838. doi:10.1016/j.freeradbiomed.2004.12.016. PMID 15749378.

nitroso, acetylpenicillamine, snap, organosulfur, compound, with, formula, onsc, nhac, co2h, green, solid, namesiupac, name, other, names, acetyl, nitrosothio, valineidentifierscas, number, 79032, model, jsmol, interactive, imageabbreviations, snapchebi, chebi. S Nitroso N acetylpenicillamine SNAP is the organosulfur compound with the formula ONSC CH3 2CH NHAc CO2H It is a green solid 2 S Nitroso N acetylpenicillamine NamesIUPAC name S Nitroso N acetylpenicillamineOther names N Acetyl 3 nitrosothio DL valineS Nitroso N acetylpenicillamineIdentifiersCAS Number 79032 48 7 Y3D model JSmol Interactive imageAbbreviations SNAPChEBI CHEBI 77702 YChEMBL ChEMBL73188 YChemSpider 5036251 YPubChem CID 6603945UNII 6E47VKF8B8 YCompTox Dashboard EPA DTXSID80897531InChI InChI 1S C7H12N2O4S c1 4 10 8 5 6 11 12 7 2 3 14 9 13 h5H 1 3H3 H 8 10 H 11 12 t5 m0 s1 YKey ZIIQCSMRQKCOCT YFKPBYRVSA N YInChI 1 C7H12N2O4S c1 4 10 8 5 6 11 12 7 2 3 14 9 13 h5H 1 3H3 H 8 10 H 11 12 t5 m0 s1Key ZIIQCSMRQKCOCT YFKPBYRVBESMILES O C N C H C O O C SN O C C CPropertiesChemical formula C7H12N2O4SMolar mass 220 25 g molAppearance green solidHazardsGHS labelling 1 PictogramsSignal word WarningHazard statements H315 H319 H335Precautionary statements P261 P264 P271 P280 P302 P352 P305 P351 P338Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa N verify what is Y N Infobox references SNAP is an S nitrosothiol and is used as a model for the general class of S nitrosothiols which have received much attention in biochemistry because nitric oxide and some organic nitroso derivatives serve as signaling molecules in living systems especially related to vasodilation 3 SNAP is derived from the amino acid penicillamine S Nitrosoglutathione is a related agent References edit N3398 h S Nitroso N acetyl DL penicillamine Sigma Aldric Retrieved 13 December 2021 Arulsamy N Bohle D S Butt J A Irvine G J Jordan P A Sagan E 1999 Interrelationships between Conformational Dynamics and the Redox Chemistry of S Nitrosothiols Journal of the American Chemical Society 121 30 7115 7123 doi 10 1021 ja9901314 Zhang Y Hogg N 2005 S Nitrosothiols Cellular Formation and Transport Free Radical Biology and Medicine 38 7 831 838 doi 10 1016 j freeradbiomed 2004 12 016 PMID 15749378 Retrieved from https en wikipedia org w index php title S Nitroso N acetylpenicillamine amp oldid 1175852499, wikipedia, wiki, book, books, library,

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