Pyrazolopyrimidines are a series of isomericheterocyclicchemical compounds with the molecular formula C6H5N3. [1] They form the central core of a variety of more complex chemical compounds including some pharmaceuticals and pesticides.
One isomer of pyrazolopyrimidines, known as pyrazolo[1,5-a]pyrimidine, is the basis for a class of sedative and anxiolyticdrugs related (in terms of their effect) to benzodiazepines.
Most of the drugs from this class marketed to date are intended to induce sleep, and are prescribed for people suffering insomnia, however some newer compounds produce anxiolytic effects with relatively little sedation, and are being developed for use as non-sedating anti-anxiety drugs.
As they are not chemically related to the benzodiazepines despite their similar effect, such drugs—as well as the imidazopyridines and cyclopyrrones—are sometimes grouped together and referred to as "nonbenzodiazepines".
^"Note that according to other sources, the structure is different, and the sum formula is C5H4N4: see pyrazolopyrimidine on". ChemSpider. Retrieved 2018-11-07.
April 10, 2024
pyrazolopyrimidine, series, isomeric, heterocyclic, chemical, compounds, with, molecular, formula, c6h5n3, they, form, central, core, variety, more, complex, chemical, compounds, including, some, pharmaceuticals, pesticides, pyrazolo, pyrimidine, namespreferre. Pyrazolopyrimidines are a series of isomeric heterocyclic chemical compounds with the molecular formula C6H5N3 1 They form the central core of a variety of more complex chemical compounds including some pharmaceuticals and pesticides Pyrazolo 1 5 a pyrimidine NamesPreferred IUPAC name Pyrazolo 1 5 a pyrimidineIdentifiersCAS Number 274 71 5 Y3D model JSmol Interactive imageChemSpider 9811537ECHA InfoCard 100 227 461PubChem CID 11636795UNII NX2KR7M4A4 YCompTox Dashboard EPA DTXSID70469781InChI InChI 1S C6H5N3 c1 3 7 6 2 4 8 9 6 5 1 h1 5HKey LDIJKUBTLZTFRG UHFFFAOYSA NInChI 1 C6H5N3 c1 3 7 6 2 4 8 9 6 5 1 h1 5HKey LDIJKUBTLZTFRG UHFFFAOYALSMILES n1cccn2nccc12PropertiesChemical formula C 6H 5N 3Molar mass 119 127 g mol 1Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Infobox references Contents 1 Pharmaceuticals 2 Pesticides 3 See also 4 ReferencesPharmaceuticals editOne isomer of pyrazolopyrimidines known as pyrazolo 1 5 a pyrimidine is the basis for a class of sedative and anxiolytic drugs related in terms of their effect to benzodiazepines Most of the drugs from this class marketed to date are intended to induce sleep and are prescribed for people suffering insomnia however some newer compounds produce anxiolytic effects with relatively little sedation and are being developed for use as non sedating anti anxiety drugs They include Zaleplon hypnotic trade name Sonata Indiplon hypnotic Ocinaplon anxiolytic Lorediplon hypnoticAs they are not chemically related to the benzodiazepines despite their similar effect such drugs as well as the imidazopyridines and cyclopyrrones are sometimes grouped together and referred to as nonbenzodiazepines nbsp ZaleplonPesticides editA related use is in pyrazolopyrimidine organothiophosphate pesticides including chlorprazophos insecticide and pyrazophos fungicide insecticide nbsp PyrazophosSee also editNonbenzodiazepineReferences edit Note that according to other sources the structure is different and the sum formula is C5H4N4 see pyrazolopyrimidine on ChemSpider Retrieved 2018 11 07 Retrieved from https en wikipedia org w index php title Pyrazolopyrimidine amp oldid 1105328234, wikipedia, wiki, book, books, library,