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Merck Millipore

Merck Millipore was the brand used by Merck Group's (not US-based Merck & Co.) global life science business until 2015 when the company re-branded. It was formed when Merck acquired the Millipore Corporation in 2010. Merck is a supplier to the life science industry. The Millipore Corporation was founded in 1954, and listed among the S&P 500 since the early 1990s, as an international biosciences company which makes micrometer pore-size filters and tests. In 2015, Merck acquired Sigma-Aldrich and merged it with Merck Millipore. In the United States and Canada, the life science business is now known as MilliporeSigma.[2][3]

MilliporeSigma
Company typePrivate formed by Merck KGaA
IndustryLife sciences
Biotech
FoundedMerck founded 1668 (Merck KGaA, Darmstadt, Germany)
Headquarters,
United States
Key people
Matthias Heinzel, CEO
ProductsFiltration
Pharmaceutical equipment and consumables
Chemistry
Biotechnology
RevenueEUR€ 6.86 billion (2020)[1]
Number of employees
More than 22,000
Websitewww.sigmaaldrich.com

History edit

Founding edit

In the early 1950s, Lovell Corporation won a contract from the U.S. Army Chemical Engineers to develop and manufacture membrane filtering devices used to separate the molecular components of fluid samples. When the membranes were declassified in 1953 and offered for commercial use, Jack Bush, son of Vannevar Bush and a Lovell employee, bought the company's technology for $200,000 and established the Millipore Filter Company. Bush coined the word millipore to refer to the numerous tiny openings in the microporous membrane product.[4] The term "millipore", originally a trademark, has since come into generic use, referring to any of several filters, made from cellulose acetate membranes, capable of removing very small particles. Later the company changed its name to Millipore Corporation to reflect its growing range of products. In 2010, Merck KGaA the world's oldest chemical and pharmaceutical company, acquired Millipore Corporation to form EMD Millipore.[citation needed]

Filters edit

By 1959, Millipore made porous membrane filters of cellulose esters or other materials which resembled paper in sheet form, and were brittle when dry but friable when wet.[5] Filters consisted of nitrocellulose or polycarbonate membrane nucleopore filters ranging from pore size of 0.2 μm (micrometer) to 20 μm. Modern filters are polyvinylidene fluoride and/or polypropylene based.

Growth edit

By 1970, Millipore had established subsidiaries in seven countries. The company opened manufacturing plants in Jaffrey, New Hampshire; Molsheim, France; Cork, Ireland; and other locations. Millipore's 2006 acquisition of Serologicals Corporation provided entry to high-growth markets for drug discovery products and services, antibodies, cell biology reagents, and stem cell research. As of the late 2000s, Millipore was the only company providing both upstream cell culture and downstream separations offerings for biopharmaceutical production.[citation needed]

Timeline edit

1950s edit

  • 1954: Jack Bush purchases the rights to a new membrane-production process developed by Lovell Chemical Company. Millipore Filter Corporation is incorporated and Bush becomes president, and later chairman
  • 1955: Millipore receives its first patent, for microporous nylon film invented by Stanley Lovell and Jack Bush

1960s edit

  • 1964: opens first subsidiary, in France
  • 1967: introduces the Super-Q water purification system
  • 1967: establishes German subsidiary
  • 1968: establishes Japanese subsidiary
  • 1968: introduces Pellicon cassette product, for purifying biotherapeutics

1970s edit

1980s edit

  • 1980: introduces low-protein binding Durapore polyvinylidene fluoride membrane
  • 1987: listed on the New York Stock Exchange
  • 1987: achieves $500 million revenue
  • 1988: opens membrane manufacturing plant in Cork, Ireland[6]

1990s edit

  • 1994: divests its Waters Chromatography Division to focus on its membrane business
  • 1996: acquires Amicon separation sciences business from W. R. Grace and Company
  • 1997: acquires Tylan General, expanding its gas purification offerings for the microelectronics industry
  • 1999: acquires Bioprocessing Limited, a developer and manufacturer of chromatography

2000s edit

  • 2001: spins off its Microelectronics Division (30% of its revenue), that becomes Mykrolis, which will merge with Entegris in 2005
  • 2002: opens Biopharmaceutical Technology Center in Billerica, Massachusetts
  • 2005: acquires MicroSafe, a European contract testing laboratory
  • 2005: acquires NovAseptic, supplier of aseptically designed components for biotech and pharmaceutical production
  • 2005: forms alliance with Gen-Probe to develop, manufacture and commercialize products for rapid microbiological and virus monitoring
  • 2006: acquires Newport Bio Systems, a maker of process containers and systems used in biopharmaceutical production
  • 2006: acquires Serologicals Corporation (including the companies Chemicon, Upstate, Linco, and Celliance), expanding its drug discovery and development footprint
  • 2006: opens a new Research and Development Center in Bedford, Massachusetts
  • 2007: launches its new brand
  • 2008: expands drug discovery and development facility in St. Charles, Missouri
  • 2008: opens membrane casting manufacturing facility in Carrigtwohill, County Cork, Ireland
  • 2009: acquires Guava Technologies, a provider of bench top cell analysis systems
  • 2009: opens Biomanufacturing Sciences and Training Center in Singapore
  • 2009: acquires BioAnaLab, a European-based firm specializing in the analysis of biologic drugs and vaccines
  • 2010: Merck KGaA acquires Millipore, which will be part of the EMD Group
  • 2015: Merck completes $17 billion acquisition of Sigma-Aldrich, combining EMD Millipore and Sigma-Aldrich to create life science company MilliporeSigma

Financial history edit

Millipore Corporation had been publicly traded on the OTC, or NASDAQ, exchange where it had paid a cash dividend to shareholders every year since 1966.[7] In 1987 Millipore Corporation moved from the NASDAQ exchange to the New York Stock Exchange, where it traded under the ticker symbol MIL.[7] Millipore Corporation was on the S&P 500 list of the largest publicly traded companies in the United States[7] until it was acquired by Merck kGaA in 2010. The deal was valued at approximately EUR 5.3 billion (US$7.2 billion).[8] Merck KGaA is not associated with Merck & Co., although the two companies stem from the same parent company.

References edit

  1. ^ "Merck KGaA, Darmstadt, Germany Annual Report 2020 – Home". emdgroup.com. Retrieved 25 June 2021.
  2. ^ . Archived from the original on 2016-02-08. Retrieved 2016-01-04.
  3. ^ About Us, EMD Millipore + Sigma-Aldrich = MilliporeSigma, The life science business of Merck KGaA, Darmstadt, Germany
  4. ^ "History of Millipore Corporation – FundingUniverse". www.fundinguniverse.com.
  5. ^ Bassett (1959). "Peripheral Nerve and Spinal Cord Regeneration: Factors Leading to Success of a Tubulation Technique Employing Millipore". Experimental Neurology 1: 386–406
  6. ^ Microfiltration membranes for filtration and venting applications.
  7. ^ a b c Standard & Poor's Stock Guide, various issues
  8. ^ "Stocks News US-Merck KGaA to buy Millipore for $6 bln". FinanzNachrichten.de.

Sources edit

External links edit

42°32′18.3″N 71°16′59.8″W / 42.538417°N 71.283278°W / 42.538417; -71.283278

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For other uses see Millipore disambiguation Merck Millipore was the brand used by Merck Group s not US based Merck amp Co global life science business until 2015 when the company re branded It was formed when Merck acquired the Millipore Corporation in 2010 Merck is a supplier to the life science industry The Millipore Corporation was founded in 1954 and listed among the S amp P 500 since the early 1990s as an international biosciences company which makes micrometer pore size filters and tests In 2015 Merck acquired Sigma Aldrich and merged it with Merck Millipore In the United States and Canada the life science business is now known as MilliporeSigma 2 3 MilliporeSigmaCompany typePrivate formed by Merck KGaAIndustryLife sciencesBiotechFoundedMerck founded 1668 Merck KGaA Darmstadt Germany HeadquartersBurlington Massachusetts United StatesKey peopleMatthias Heinzel CEOProductsFiltrationPharmaceutical equipment and consumablesChemistry BiotechnologyRevenueEUR 6 86 billion 2020 1 Number of employeesMore than 22 000Websitewww sigmaaldrich com Contents 1 History 1 1 Founding 1 2 Filters 1 3 Growth 2 Timeline 2 1 1950s 2 2 1960s 2 3 1970s 2 4 1980s 2 5 1990s 2 6 2000s 3 Financial history 4 References 4 1 Sources 5 External linksHistory editFounding edit In the early 1950s Lovell Corporation won a contract from the U S Army Chemical Engineers to develop and manufacture membrane filtering devices used to separate the molecular components of fluid samples When the membranes were declassified in 1953 and offered for commercial use Jack Bush son of Vannevar Bush and a Lovell employee bought the company s technology for 200 000 and established the Millipore Filter Company Bush coined the word millipore to refer to the numerous tiny openings in the microporous membrane product 4 The term millipore originally a trademark has since come into generic use referring to any of several filters made from cellulose acetate membranes capable of removing very small particles Later the company changed its name to Millipore Corporation to reflect its growing range of products In 2010 Merck KGaA the world s oldest chemical and pharmaceutical company acquired Millipore Corporation to form EMD Millipore citation needed Filters edit By 1959 Millipore made porous membrane filters of cellulose esters or other materials which resembled paper in sheet form and were brittle when dry but friable when wet 5 Filters consisted of nitrocellulose or polycarbonate membrane nucleopore filters ranging from pore size of 0 2 mm micrometer to 20 mm Modern filters are polyvinylidene fluoride and or polypropylene based Growth edit By 1970 Millipore had established subsidiaries in seven countries The company opened manufacturing plants in Jaffrey New Hampshire Molsheim France Cork Ireland and other locations Millipore s 2006 acquisition of Serologicals Corporation provided entry to high growth markets for drug discovery products and services antibodies cell biology reagents and stem cell research As of the late 2000s Millipore was the only company providing both upstream cell culture and downstream separations offerings for biopharmaceutical production citation needed Timeline edit1950s edit 1954 Jack Bush purchases the rights to a new membrane production process developed by Lovell Chemical Company Millipore Filter Corporation is incorporated and Bush becomes president and later chairman 1955 Millipore receives its first patent for microporous nylon film invented by Stanley Lovell and Jack Bush 1960s edit 1964 opens first subsidiary in France 1967 introduces the Super Q water purification system 1967 establishes German subsidiary 1968 establishes Japanese subsidiary 1968 introduces Pellicon cassette product for purifying biotherapeutics 1970s edit 1971 introduces the original Millex syringe filter the first disposable syringe filter 1972 opens subsidiary in Spain 1972 opens a manufacturing plant in Jaffrey New Hampshire 1973 starts manufacturing in Molsheim France 1973 introduces the Milli Q water purification system the first lab scale ultrapure water system 1978 reaches 100 million revenue 1978 opens manufacturing plant in Danvers Massachusetts 1979 acquires Waters Associates Inc a producer of chromatographic media and High performance liquid chromatography instrumentation 1980s edit 1980 introduces low protein binding Durapore polyvinylidene fluoride membrane 1987 listed on the New York Stock Exchange 1987 achieves 500 million revenue 1988 opens membrane manufacturing plant in Cork Ireland 6 1990s edit 1994 divests its Waters Chromatography Division to focus on its membrane business 1996 acquires Amicon separation sciences business from W R Grace and Company 1997 acquires Tylan General expanding its gas purification offerings for the microelectronics industry 1999 acquires Bioprocessing Limited a developer and manufacturer of chromatography 2000s edit 2001 spins off its Microelectronics Division 30 of its revenue that becomes Mykrolis which will merge with Entegris in 2005 2002 opens Biopharmaceutical Technology Center in Billerica Massachusetts 2005 acquires MicroSafe a European contract testing laboratory 2005 acquires NovAseptic supplier of aseptically designed components for biotech and pharmaceutical production 2005 forms alliance with Gen Probe to develop manufacture and commercialize products for rapid microbiological and virus monitoring 2006 acquires Newport Bio Systems a maker of process containers and systems used in biopharmaceutical production 2006 acquires Serologicals Corporation including the companies Chemicon Upstate Linco and Celliance expanding its drug discovery and development footprint 2006 opens a new Research and Development Center in Bedford Massachusetts 2007 launches its new brand 2008 expands drug discovery and development facility in St Charles Missouri 2008 opens membrane casting manufacturing facility in Carrigtwohill County Cork Ireland 2009 acquires Guava Technologies a provider of bench top cell analysis systems 2009 opens Biomanufacturing Sciences and Training Center in Singapore 2009 acquires BioAnaLab a European based firm specializing in the analysis of biologic drugs and vaccines 2010 Merck KGaA acquires Millipore which will be part of the EMD Group 2015 Merck completes 17 billion acquisition of Sigma Aldrich combining EMD Millipore and Sigma Aldrich to create life science company MilliporeSigmaFinancial history editMillipore Corporation had been publicly traded on the OTC or NASDAQ exchange where it had paid a cash dividend to shareholders every year since 1966 7 In 1987 Millipore Corporation moved from the NASDAQ exchange to the New York Stock Exchange where it traded under the ticker symbol MIL 7 Millipore Corporation was on the S amp P 500 list of the largest publicly traded companies in the United States 7 until it was acquired by Merck kGaA in 2010 The deal was valued at approximately EUR 5 3 billion US 7 2 billion 8 Merck KGaA is not associated with Merck amp Co although the two companies stem from the same parent company References edit Merck KGaA Darmstadt Germany Annual Report 2020 Home emdgroup com Retrieved 25 June 2021 Customer Letter Archived from the original on 2016 02 08 Retrieved 2016 01 04 About Us EMD Millipore Sigma Aldrich MilliporeSigma The life science business of Merck KGaA Darmstadt Germany History of Millipore Corporation FundingUniverse www fundinguniverse com Bassett 1959 Peripheral Nerve and Spinal Cord Regeneration Factors Leading to Success of a Tubulation Technique Employing Millipore Experimental Neurology 1 386 406 Microfiltration membranes for filtration and venting applications a b c Standard amp Poor s Stock Guide various issues Stocks News US Merck KGaA to buy Millipore for 6 bln FinanzNachrichten de Sources edit https cen acs org articles 93 web 2015 11 merck kgaa completes sigma aldrich acquisition htmlExternal links editMillipore Corporation web site http www emdmillipore com US en 42 32 18 3 N 71 16 59 8 W 42 538417 N 71 283278 W 42 538417 71 283278 Retrieved from https en wikipedia org w index php title Merck Millipore amp oldid 1224106122, wikipedia, wiki, book, books, library,

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