Gallamine triethiodide was commonly used to prevent muscle contractions during surgical procedures, but now superseded by new neuromuscular blocking drugs with less side effects.
^"Webster's Online Dictionary - Flaxedil". Retrieved 2008-12-15.[permanent dead link]
^"RxMed: Pharmaceutical Information - FLAXEDIL". Retrieved 2008-12-15.
^Morgenstern C, Splith G (October 1965). "[Studies on the causes of gallamine tachycardia and its antagonistic modification by beta adrenolytics]". Der Anaesthesist (in German). 14 (10): 298–301. PMID 4380161.
^Walts LF (1963). "Ventricular tachycardia with gallamine and cyclopropane anesthesia". Anesthesiology. 24: 119. doi:10.1097/00000542-196301000-00024. PMID 13998750.
^Raghavendra T (July 2002). "Neuromuscular blocking drugs: discovery and development". Journal of the Royal Society of Medicine. 95 (7): 363–7. doi:10.1177/014107680209500713. PMC1279945. PMID 12091515.
gallamine, triethiodide, flaxedil, depolarising, muscle, relaxant, acts, combining, with, cholinergic, receptor, sites, muscle, competitively, blocking, transmitter, action, acetylcholine, gallamine, depolarising, type, blocker, binds, acetylcholine, receptor,. Gallamine triethiodide Flaxedil is a non depolarising muscle relaxant 1 It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine 2 Gallamine is a non depolarising type of blocker as it binds to the acetylcholine receptor but does not have the biological activity of acetyl choline Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia 3 4 and occasionally hypertension Very high doses cause histamine release citation needed Presence of iodine makes it radio opaque and its ampule in a bag at airport s x ray scanner raise the false suspicion of a bullet in the bag Gallamine triethiodideClinical dataTrade namesFlaxedilAHFS Drugs comInternational Drug NamesATC codeM03AC02 WHO IdentifiersIUPAC name 2 2 2 benzene 1 2 3 triyltris oxy tris N N N triethylethanaminium triiodideCAS Number65 29 2 YPubChem CID6172IUPHAR BPS356DrugBankDB00483 YChemSpider5937 NUNIIQ3254X40X2KEGGD02292 YChEBICHEBI 503442 YChEMBLChEMBL1200993 NChemical and physical dataFormulaC30H60N3O3 3 3 I gallamine triethiodide C24H45N3O3 gallamine Molar mass891 529 g mol gallamine triethiodide 423 633 g mol gallamine 3D model JSmol Interactive imageSMILES I I I O c1c OCC N CC CC CC cccc1OCC N CC CC CC CC N CC CC CCInChI InChI 1S C24H45N3O3 c1 7 25 8 2 16 19 28 22 14 13 15 23 29 20 17 26 9 3 10 4 24 22 30 21 18 27 11 5 12 6 h13 15H 7 12 16 21H2 1 6H3 YKey ICLWTJIMXVISSR UHFFFAOYSA N Y N Y what is this verify An ampoule of gallamine Gallamine triethiodide was commonly used to prevent muscle contractions during surgical procedures but now superseded by new neuromuscular blocking drugs with less side effects It was developed by Daniel Bovet in 1947 5 The drug is no longer marketed in the United States according to the FDA Orange Book See also EditNeuromuscular blocking drug CurareReferences Edit Webster s Online Dictionary Flaxedil Retrieved 2008 12 15 permanent dead link RxMed Pharmaceutical Information FLAXEDIL Retrieved 2008 12 15 Morgenstern C Splith G October 1965 Studies on the causes of gallamine tachycardia and its antagonistic modification by beta adrenolytics Der Anaesthesist in German 14 10 298 301 PMID 4380161 Walts LF 1963 Ventricular tachycardia with gallamine and cyclopropane anesthesia Anesthesiology 24 119 doi 10 1097 00000542 196301000 00024 PMID 13998750 Raghavendra T July 2002 Neuromuscular blocking drugs discovery and development Journal of the Royal Society of Medicine 95 7 363 7 doi 10 1177 014107680209500713 PMC 1279945 PMID 12091515 This drug article relating to the musculoskeletal system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Gallamine triethiodide amp oldid 1164513753, wikipedia, wiki, book, books, library,
