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Wikipedia

Fustin

Fustin, sometimes called "dihydrofisetin", is a flavanonol, a type of flavonoid. It can be found in young fustic (Cotinus coggygria)[1] and in the lacquer tree (Toxicodendron vernicifluum).[2]

Fustin
Names
IUPAC name
(2R,3R)-3,3′,4′,7-Tetrahydroxyflavan-4-one
Systematic IUPAC name
(2R,3R)-2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
Other names
2,3-Dihydrofisetin
3,7,3',4'-Tetrahydroxyflavanone
2,3-Dihydrofisetin
3′,4′,7-Trihydroxyflavanol
Identifiers
  • 20725-03-5 Y
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:5202
ChEMBL
  • ChEMBL470267
ChemSpider
  • 4476304
ECHA InfoCard 100.039.975
EC Number
  • 243-989-6
KEGG
  • C01378
  • 5317435
UNII
  • 4994C1X19A Y
  • InChI=1S/C15H12O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,14-18,20H/t14-,15+/m0/s1
    Key: FNUPUYFWZXZMIE-LSDHHAIUSA-N
  • C1=CC(=C(C=C1[C@@H]2[C@H](C(=O)C3=C(O2)C=C(C=C3)O)O)O)O
Properties
C15H12O6
Molar mass 288.255 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)

Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.[2]

Unlike fisetin, fustin has no double bond in the C-ring. This makes fustin a flavan, with two stereocenters and four stereoisomers.

References edit

  1. ^ Valianou, Lemonia; Stathopoulou, Konstantina; Karapanagiotis, Ioannis; Magiatis, Prokopios; Pavlidou, Eleni; Skaltsounis, Alexios-Leandros; Chryssoulakis, Yannis (2009). "Phytochemical analysis of young fustic (Cotinus coggygria heartwood) and identification of isolated colourants in historical textiles". Analytical and Bioanalytical Chemistry. 394 (3): 871. doi:10.1007/s00216-009-2767-z. PMID 19352635. S2CID 22188491.
  2. ^ a b Park, Byung Chul; Lee, Yong Soo; Park, Hee-Juhn; Kwak, Mi-Kyoung; Yoo, Bong Kyu; Kim, Joo Young; Kim, Jung-Ae (2007). "Protective effects of fustin, a flavonoid from Rhus verniciflua Stokes, on 6-hydroxydopamine-induced neuronal cell death". Experimental & Molecular Medicine. 39 (3): 316. doi:10.1038/emm.2007.35. PMID 17603285.

fustin, sometimes, called, dihydrofisetin, flavanonol, type, flavonoid, found, young, fustic, cotinus, coggygria, lacquer, tree, toxicodendron, vernicifluum, namesiupac, name, tetrahydroxyflavan, onesystematic, iupac, name, dihydroxyphenyl, dihydroxy, dihydro,. Fustin sometimes called dihydrofisetin is a flavanonol a type of flavonoid It can be found in young fustic Cotinus coggygria 1 and in the lacquer tree Toxicodendron vernicifluum 2 Fustin NamesIUPAC name 2R 3R 3 3 4 7 Tetrahydroxyflavan 4 oneSystematic IUPAC name 2R 3R 2 3 4 Dihydroxyphenyl 3 7 dihydroxy 2 3 dihydro 4H 1 benzopyran 4 oneOther names 2 3 Dihydrofisetin3 7 3 4 Tetrahydroxyflavanone2 3 Dihydrofisetin3 4 7 TrihydroxyflavanolIdentifiersCAS Number 20725 03 5 Y3D model JSmol Interactive imageChEBI CHEBI 5202ChEMBL ChEMBL470267ChemSpider 4476304ECHA InfoCard 100 039 975EC Number 243 989 6KEGG C01378PubChem CID 5317435UNII 4994C1X19A YInChI InChI 1S C15H12O6 c16 8 2 3 9 12 6 8 21 15 14 20 13 9 19 7 1 4 10 17 11 18 5 7 h1 6 14 18 20H t14 15 m0 s1Key FNUPUYFWZXZMIE LSDHHAIUSA NSMILES C1 CC C C C1 C H 2 C H C O C3 C O2 C C C C3 O O O OPropertiesChemical formula C 15H 12O 6Molar mass 288 255 g mol 1Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Y verify what is Y N Infobox references Fustin shows protective effects on 6 hydroxydopamine induced neuronal cell death 2 Unlike fisetin fustin has no double bond in the C ring This makes fustin a flavan with two stereocenters and four stereoisomers References edit Valianou Lemonia Stathopoulou Konstantina Karapanagiotis Ioannis Magiatis Prokopios Pavlidou Eleni Skaltsounis Alexios Leandros Chryssoulakis Yannis 2009 Phytochemical analysis of young fustic Cotinus coggygria heartwood and identification of isolated colourants in historical textiles Analytical and Bioanalytical Chemistry 394 3 871 doi 10 1007 s00216 009 2767 z PMID 19352635 S2CID 22188491 a b Park Byung Chul Lee Yong Soo Park Hee Juhn Kwak Mi Kyoung Yoo Bong Kyu Kim Joo Young Kim Jung Ae 2007 Protective effects of fustin a flavonoid from Rhus verniciflua Stokes on 6 hydroxydopamine induced neuronal cell death Experimental amp Molecular Medicine 39 3 316 doi 10 1038 emm 2007 35 PMID 17603285 Retrieved from https en wikipedia org w index php title Fustin amp oldid 1152729688, wikipedia, wiki, book, books, library,

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