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Andreas Vesalius

Andreas Vesalius (Latinized from Andries van Wezel) (/vɪˈsliəs/;[2] 31 December 1514 – 15 October 1564) was a 16th-century anatomist, physician, and author of one of the most influential books on human anatomy, De Humani Corporis Fabrica Libri Septem (On the fabric of the human body in seven books). Vesalius is often referred to as the founder of modern human anatomy. He was born in Brussels, which was then part of the Habsburg Netherlands. He was a professor at the University of Padua (1537–1542) and later became Imperial physician at the court of Emperor Charles V.

Andreas Vesalius
Portrait by Jan van Calcar
Born
Andries van Wezel

31 December 1514
Died15 October 1564(1564-10-15) (aged 49)
EducationUniversity of Leuven (M.D., 1537)
University of Paris
Known forDe humani corporis fabrica (On the Fabric of the Human Body)
Scientific career
FieldsAnatomy
InstitutionsUniversity of Padua (1537–1542)
ThesisParaphrasis in nonum librum Rhazae medici Arabis clarissimi ad regem Almansorem, de affectuum singularum corporis partium curatione (1537)
Academic advisorsJohann Winter von Andernach[1]
Jacques Dubois[1]
Jean Fernel[1]
Notable studentsJohn Caius
Realdo Colombo
Gabriele Falloppio
InfluencesGalen
Gemma Frisius
Johannes Baptista Montanus
Signature

Andreas Vesalius is the Latinized form of the Dutch name Andries van Wesel. It was a common practice among European scholars in his time to Latinize their names. His name is also given as Andrea Vesalius, André Vésale, Andrea Vesalio, Andreas Vesal, Andrés Vesalio and Andre Vesale.

Early life and education

Vesalius was born as Andries van Wesel to his father Anders van Wesel and mother Isabel Crabbe on 31 December 1514 in Brussels, which was then part of the Habsburg Netherlands. His great-grandfather, Jan van Wesel, probably born in Wesel, received a medical degree from the University of Pavia and taught medicine at the University of Leuven. His grandfather, Everard van Wesel, was the Royal Physician of Emperor Maximilian, whilst his father, Anders van Wesel, served as apothecary to Maximilian and later valet de chambre to his successor, Charles V. Anders encouraged his son to continue in the family tradition and enrolled him in the Brethren of the Common Life in Brussels to learn Greek and Latin prior to learning medicine, according to standards of the era.[3]

In 1528 Vesalius entered the University of Leuven (Pedagogium Castrense) taking arts, but when his father was appointed as the Valet de Chambre in 1532 he decided instead to pursue a career in the military at the University of Paris, where he moved in 1533. There he studied the theories of Galen under the auspices of Johann Winter von Andernach, Jacques Dubois (Jacobus Sylvius) and Jean Fernel. It was during that time that he developed an interest in anatomy and was often found examining excavated bones in the charnel houses at the Cemetery of the Innocents.

Vesalius was forced to leave Paris in 1536 owing to the opening of hostilities between the Holy Roman Empire and France and returned to the University of Leuven. He completed his studies there and graduated the following year. His doctoral thesis, Paraphrasis in nonum librum Rhazae medici Arabis clarissimi ad regem Almansorem, de affectuum singularum corporis partium curatione, was a commentary on the ninth book of Rhazes.

Medical career and accomplishments

On the day of his graduation he was immediately offered the chair of surgery and anatomy (explicator chirurgiae) at the University of Padua. He also guest-lectured at the University of Bologna and the University of Pisa. Prior to taking up his position in Padua, Vesalius traveled through Italy and assisted the future Pope Paul IV and Ignatius of Loyola to heal those afflicted by leprosy. In Venice in 1542 he met the illustrator Johan van Calcar, a student of Titian. It was with van Calcar that Vesalius published his first anatomical text, Tabulae Anatomicae Sex, in 1538.[4] Previously these topics had been taught primarily from reading classical texts, mainly Galen, followed by an animal dissection by a barber–surgeon whose work was directed by the lecturer. No attempt was made to confirm Galen's claims, which were considered unassailable. Vesalius, in contrast, performed dissection as the primary teaching tool, handling the actual work himself and urging students to perform dissection themselves. He considered hands-on direct observation to be the only reliable resource.

Vesalius created detailed illustrations of anatomy for students in the form of six large woodcut posters. When he found that some of them were being widely copied, he published them all in 1538 under the title Tabulae anatomicae sex. He followed this in 1539 with an updated version of Winter's anatomical handbook, Institutiones anatomicae.

In 1539 he also published his Venesection Epistle on bloodletting. This was a popular treatment for almost any illness, but there was some debate about where to take the blood from. The classical Greek procedure, advocated by Galen, was to collect blood from a site near the location of the illness. However the Muslim and medieval practice was to draw a smaller amount of blood from a distant location. Vesalius' pamphlet generally supported Galen's view but with qualifications that rejected the infiltration of Galen.

In 1541, while in Bologna, Vesalius discovered that all of Galen's research was restricted to animals, since dissection had been banned in ancient Rome.[citation needed] Galen had dissected Barbary macaques instead, which he considered structurally closest to man. Even though Galen produced many errors owing to the anatomical material available to him, he was a qualified examiner, but his research was weakened by stating his findings philosophically, so his findings were based on religious precepts rather than science.[5] Vesalius contributed to the new Giunta edition of Galen's collected works and began to write his own anatomical text based on his own research. Until Vesalius pointed out Galen's substitution of animal for human anatomy, it had gone unnoticed and had long been the basis of studying human anatomy. However some people still chose to follow Galen and resented Vesalius for calling attention to the difference.

Galen had assumed that arteries carried the purest blood to higher organs such as the brain and lungs from the left ventricle of the heart, while veins carried blood to the lesser organs such as the stomach from the right ventricle. In order for this theory to be correct, some kind of opening was needed to interconnect the ventricles, and Galen claimed to have found them. So paramount was Galen's authority that for 1400 years a succession of anatomists had claimed to find these holes, until Vesalius admitted he could not find them. Nonetheless, he did not venture to dispute Galen on the distribution of blood, being unable to offer any other solution, and so supposed that it diffused through the unbroken partition between the ventricles.[6]

Other famous examples of Vesalius disproving Galen's assertions were his discoveries that the lower jaw (mandible) was composed of only one bone, not two (which Galen had assumed based on animal dissection) and that humans lack the rete mirabile, a network of blood vessels at the base of the brain that is found in sheep and other ungulates.

 
The skeleton of Jakob Karrer, articulated by Vesalius in 1543

In 1543, Vesalius conducted a public dissection of the body of Jakob Karrer von Gebweiler, a notorious felon from the city of Basel, Switzerland. He assembled and articulated the bones, finally donating the skeleton to the University of Basel. This preparation ("The Basel Skeleton") is Vesalius' only well-preserved skeletal preparation, and also the world's oldest surviving anatomical preparation. It is still displayed at the Anatomical Museum of the University of Basel.[7]

In the same year Vesalius took residence in Basel to help Johannes Oporinus publish the seven-volume De humani corporis fabrica (On the fabric of the human body), a groundbreaking work of human anatomy that he dedicated to Charles V. Many believe it was illustrated by Titian's pupil Jan Stephen van Calcar, but evidence is lacking, and it is unlikely that a single artist created all 273 illustrations in a period of time so short. At about the same time he published an abridged edition for students, Andrea Vesalii suorum de humani corporis fabrica librorum epitome, and dedicated it to Philip II of Spain, the son of the Emperor. That work, now collectively referred to as the Fabrica of Vesalius, was groundbreaking in the history of medical publishing and is considered to be a major step in the development of scientific medicine. Because of this, it marks the establishment of anatomy as a modern descriptive science.[8]

Though Vesalius' work was not the first such work based on actual dissection, nor even the first work of this era, the production quality, highly detailed and intricate plates, and the likelihood that the artists who produced it were clearly present in person at the dissections made it an instant classic. Pirated editions were available almost immediately, an event Vesalius acknowledged in a printer's note would happen. Vesalius was 28 years old when the first edition of Fabrica was published.

Imperial physician and death

 
The Holy Roman Emperor, Charles V, who was an important patron of Vesalius

Soon after publication, Vesalius was invited to become imperial physician to the court of Emperor Charles V. He informed the Venetian Senate that he would leave his post at Padua, which prompted Duke Cosimo I de' Medici to invite him to move to the expanding university in Pisa, which he declined. Vesalius took up the offered position in the imperial court, where he had to deal with other physicians who mocked him for being a mere barber surgeon instead of an academic working on the respected basis of theory.

In the 1540s, shortly after entering in service of the emperor, Vesalius married Anne van Hamme, from Vilvorde, Belgium. They had one daughter, named Anne, who died in 1588.[9]

Over the next eleven years Vesalius traveled with the court, treating injuries caused in battle or tournaments, performing postmortems, administering medication, and writing private letters addressing specific medical questions. During these years he also wrote the Epistle on the China root, a short text on the properties of a medical plant whose efficacy he doubted, as well as a defense of his anatomical findings. This elicited a new round of attacks on his work that called for him to be punished by the emperor. In 1551, Charles V commissioned an inquiry in Salamanca to investigate the religious implications of his methods. Although Vesalius' work was cleared by the board, the attacks continued. Four years later one of his main detractors and one-time professors, Jacobus Sylvius, published an article that claimed that the human body itself had changed since Galen had studied it.

In 1555, Vesalius became physician to Philip II,[10] and in the same year he published a revised edition of De humani corporis fabrica.

In 1564 Vesalius went on a pilgrimage to the Holy Land, some said, in penance after being accused of dissecting a living body. He sailed with the Venetian fleet under James Malatesta via Cyprus. When he reached Jerusalem he received a message from the Venetian senate requesting him again to accept the Paduan professorship, which had become vacant on the death of his friend and pupil Fallopius.

After struggling for many days with adverse winds in the Ionian Sea, he was shipwrecked on the island of Zakynthos.[11] Here he soon died, in such debt that a benefactor kindly paid for his funeral. At the time of his death he was 49 years old. He was buried somewhere on the island of Zakynthos (Zante).[12]

For some time, it was assumed that Vesalius's pilgrimage was due to the pressures imposed on him by the Inquisition. Today, this assumption is generally considered to be without foundation[13] and is dismissed by modern biographers. It appears the story was spread by Hubert Languet, a diplomat under Emperor Charles V and then under the Prince of Orange, who claimed in 1565 that Vesalius had performed an autopsy on an aristocrat in Spain while the heart was still beating, leading to the Inquisition's condemning him to death. The story went on to claim that Philip II had the sentence commuted to a pilgrimage. That story re-surfaced several times, until it was more recently revised.

The decision to undertake the pilgrimage was likely just a pretext to leave the Spanish court. Its lifestyle did not please him and he longed to continue his research. Given that he could not get rid of his royal service by resignation, he managed to escape asking for the permission to go to Jerusalem.[14]

Publications

De Humani Corporis Fabrica

 
A portrait of Vesalius from his De Humani Corporis Fabrica (1543)

In 1543, Vesalius asked Johannes Oporinus to publish the book De Humani Corporis Fabrica Libri Septem (On the fabric of the human body in seven books), a groundbreaking work of human anatomy he dedicated to Charles V and which many believe was illustrated by Titian's pupil Jan Stephen van Calcar.

About the same time he published another version of his great work, entitled De Humani Corporis Fabrica Librorum Epitome (Abridgement of the On the fabric of the human body) more commonly known as the Epitome, with a stronger focus on illustrations than on text, so as to help readers, including medical students, to easily understand his findings. The actual text of the Epitome was an abridged form of his work in the Fabrica, and the organization of the two books was quite varied. He dedicated it to Philip II of Spain, son of the Emperor.[15]

The Fabrica emphasized the priority of dissection and what has come to be called the "anatomical" view of the body, seeing human internal functioning as a result of an essentially corporeal structure filled with organs arranged in three-dimensional space. His book contains drawings of several organs on two leaves. This allows for the creation of three-dimensional diagrams by cutting out the organs and pasting them on flayed figures.[8] This was in stark contrast to many of the anatomical models used previously, which had strong Galenic/Aristotelean elements, as well as elements of astrology. Although modern anatomical texts had been published by Mondino and Berenger, much of their work was clouded by reverence for Galen and Arabian doctrines.

 
Vesalius's Fabrica contained many intricately detailed drawings of human dissections, often in allegorical poses.

Besides the first good description of the sphenoid bone, he showed that the sternum consists of three portions and the sacrum of five or six, and described accurately the vestibule in the interior of the temporal bone. He not only verified Estienne's observations on the valves of the hepatic veins, but also described the vena azygos, and discovered the canal which passes in the fetus between the umbilical vein and the vena cava, since named the ductus venosus. He described the omentum and its connections with the stomach, the spleen and the colon; gave the first correct views of the structure of the pylorus; observed the small size of the caecal appendix in man; gave the first good account of the mediastinum and pleura and the fullest description of the anatomy of the brain up to that time. He did not understand the inferior recesses, and his account of the nerves is confused by regarding the optic as the first pair, the third as the fifth, and the fifth as the seventh.

In this work, Vesalius also becomes the first person to describe mechanical ventilation.[16] It is largely this achievement that has resulted in Vesalius being incorporated into the Australian and New Zealand College of Anaesthetists college arms and crest.

Excerpts

When I undertake the dissection of a human pelvis I pass a stout rope tied like a noose beneath the lower jaw and through the zygomas up to the top of the head... The lower end of the noose I run through a pulley fixed to a beam in the room so that I may raise or lower the cadaver as it hangs there or turn around in any direction to suit my purpose; ... You must take care not to put the noose around the neck, unless some of the muscles connected to the occipital bone have already been cut away.[17]

Other publications

In 1538, Vesalius wrote Epistola, docens venam axillarem dextri cubiti in dolore laterali secandam (A letter, teaching that in cases of pain in the side, the axillary vein of the right elbow be cut), commonly known as the Venesection Letter, which demonstrated a revived venesection, a classical procedure in which blood was drawn near the site of the ailment. He sought to locate the precise site for venesection in pleurisy within the framework of the classical method. The real significance of the book is his attempt to support his arguments by the location and continuity of the venous system from his observations rather than appeal to earlier published works. With this novel approach to the problem of venesection, Vesalius posed the then striking hypothesis that anatomical dissection might be used to test speculation.

In 1546, three years after the Fabrica, he wrote his Epistola rationem modumque propinandi radicis Chynae decocti, commonly known as the Epistle on the China Root. Ostensibly an appraisal of a popular but ineffective treatment for gout, syphilis, and stones, this work is especially important as a continued polemic against Galenism and a reply to critics in the camp of his former professor Jacobus Sylvius, now an obsessive detractor.

In February 1561, Vesalius was given a copy of Gabriele Fallopio's Observationes anatomicae, friendly additions and corrections to the Fabrica. Before the end of the year Vesalius composed a cordial reply, Anatomicarum Gabrielis Fallopii observationum examen, generally referred to as the Examen. In this work he recognizes in Fallopio a true equal in the science of dissection he had done so much to create. Vesalius' reply to Fallopio was published in May 1564, a month after Vesalius' death on the Greek island of Zante (now called Zakynthos).

Scientific findings

Skeletal system

  • Vesalius believed the skeletal system to be the framework of the human body. It was in this opening chapter or book of De fabrica that Vesalius made several of his strongest claims against Galen's theories and writings which he had put in his anatomy books. In his extensive study of the skull, Vesalius claimed that the mandible consisted of one bone, whereas Galen had thought it to be two separate bones. He accurately described the vestibule in the interior of the temporal bone of the skull.
  • In Galen's observation of the ape, he had discovered that their sternum consisted of seven parts which he assumed also held true for humans. Vesalius discovered that the human sternum consisted of only three parts.
  • He also disproved the common belief that men had one rib fewer than women and noted that the fibula and tibia bones of the leg were indeed larger than the humerus bone of the arm, unlike Galen's original findings.

Muscular system

  • Vesalius' most impressive contribution to the study of the muscular system may be the illustrations that accompany the text in De fabrica, which would become known as the "muscle men". He describes the source and position of each muscle of the body and provides information on their respective operation.

Vascular and circulatory systems

  • Vesalius' work on the vascular and circulatory systems was his greatest contribution to modern medicine. In his dissections of the heart, Vesalius became convinced that Galen's claims of a porous interventricular septum were false. This fact was previously described by Michael Servetus, a fellow of Vesalius, but never reached the public, for it was written down in the "Manuscript of Paris",[18] in 1546, and published later in his Christianismi Restitutio (1553), a book regarded as heretical by the Inquisition. Only three copies survived, but these remained hidden for decades, the rest having been burned shortly after publication. In the second edition Vesalius published that the septum was indeed waterproof, discovering (and naming), the mitral valve to explain the blood flow.
  • Vesalius believed that cardiac systole is synchronous with the arterial pulse.
  • He not only verified Estienne's findings on the valves of the hepatic veins, but also described the azygos vein, and discovered the canal which passes into the fetus between the umbilical vein and vena cava.

Nervous system

  • Vesalius defined a nerve as the mode of transmitting sensation and motion and thus refuted his contemporaries' claims that ligaments, tendons and aponeuroses were three types of nerve units.
  • He believed that the brain and the nervous system are the center of the mind and emotion in contrast to the common Aristotelian belief that the heart was the center of the body. He correspondingly believed that nerves themselves do not originate from the heart, but from the brain—facts already experimentally proved by Herophilus and Erasistratus in the classical era, but suppressed after the adoption of Aristotelianism by the Catholic Church in the Middle Ages.
  • Upon studying the optic nerve, Vesalius came to the conclusion that nerves were not hollow.

Abdominal organs

  • In De fabrica, he corrected an earlier claim he made in Tabulae about the right kidney being set higher than the left. Vesalius claimed that the kidneys were not a filter device for urine to pass through, but rather that the kidneys serve to filter blood as well, and that excretions from the kidneys travelled through the ureters to the bladder.
  • He described the omentum, and its connections with the stomach, the spleen and the colon gave the first correct views of the structure of the pylorus.
  • He also observed the small size of the caecal appendix in man and gave the first good account of the mediastinum and pleura.
  • Vesalius admitted that due to a lack of pregnant cadavers he was unable to come to a significant understanding of the reproductive organs. However, he did find that the uterus had been falsely identified as having two distinct sections.

Heart

  • Through his work with muscles, Vesalius believed that a criterion for muscles was their voluntary motion. On this claim, he deduced that the heart was not a true muscle due to the obvious involuntary nature of its motion.
  • He identified two chambers and two atria. The right atrium was considered a continuation of the inferior and superior venae cavae, and the left atrium was considered a continuation of the pulmonary vein.
  • He also addressed the controversial issue of the heart being the centre of the soul. He wished to avoid drawing any conclusions due to possible conflict with contemporary religious beliefs.
     
    Base of the brain, showing the optic chiasma, cerebellum, olfactory bulbs, etc.
  • Against Galen's theory and many beliefs he also discovered that there was no hole in the septum or heart.

Other achievements

  • Vesalius disproved Galen's assertion that men have more teeth than women.[11]
  • Vesalius introduced the notion of induction of the extraction of empyema through surgical means.
  • Due to his impressive study of the human skull and the variations in its features he is said to have been responsible for the launch of the study of physical anthropology.
  • Vesalius always encouraged his students to check their findings, and even his own findings, so that they could better understand the structure of the human body.
  • In addition to his continual efforts to study anatomy he also worked on medicinal remedies and came to such conclusions as treating syphilis with chinaroot.
  • Vesalius claimed that medicine had three aspects: drugs, diet, and 'the use of hands'—mainly suggesting surgery and the knowledge of anatomy and physiology gained through dissection.
  • Vesalius was a supporter of 'parallel dissections' in which an animal cadaver and a human cadaver are dissected simultaneously in order to demonstrate the anatomical differences and thus correct Galenic errors.

Scientific and historical impact

The influence of Vesalius' plates representing the partial dissections of the human figure posing in a landscape setting is apparent in the anatomical plates prepared by the Baroque painter Pietro da Cortona (1596–1669), who executed anatomical plates with figures in dramatic poses, most of them with architectural or landscape backdrops.[19]

In 1844, botanists Martin Martens and Henri Guillaume Galeotti published Vesalea, which is a plant genus in the honeysuckle family Caprifoliaceae and it was named in Vesalius's honour.[20]

See also

References

  1. ^ a b c Andreas Vesalius of Brussels, 1514-1564 / [Charles Donald O'Malley]. Wellcome Collection. University of California Press, 1964. p. 47. OCLC 429258. from the original on 23 February 2022. Retrieved 23 February 2022.
  2. ^ "Vesalius | Dictionary.com". www.dictionary.com. from the original on 23 February 2022. Retrieved 23 February 2022.
  3. ^ O'Malley, Charles Donald. Andreas Vesalius of Brussels, 1514–1564. Berkeley : University of California Press, 1964. pp. 21–27.
  4. ^ . The Physician's Palette. Archived from the original on 10 December 2014.
  5. ^ O'Malley, Charles Donald. Andreas Vesalius of Brussels, 1514–1564. Berkeley : University of California Press, 1964.
  6. ^ Bonnier Corporation (May 1872). "Popular Science". The Popular Science Monthly. Bonnier Corporation: 95–100. ISSN 0161-7370.
  7. ^ (PDF). Archived from the original (PDF) on 27 September 2007. Retrieved 10 October 2009.{{cite web}}: CS1 maint: archived copy as title (link)
  8. ^ a b Harcourt, Glenn (1 January 1987). "Andreas Vesalius and the Anatomy of Antique Sculpture". Representations. 17 (17): 28–61. doi:10.2307/3043792. ISSN 0734-6018. JSTOR 3043792. PMID 11618035.
  9. ^ O'Malley, Charles Donald. Andreas Vesalius of Brussels, 1514–1564. Berkeley : University of California Press, 1964. pp. 203, 314.
  10. ^ "Andreas Vesalius (1514-1564)". BBC History. Retrieved 14 March 2022.
  11. ^ a b Lambert Teuwissen (31 December 2014). "Vesalius was belangrijker dan Copernicus" (in Dutch). Nederlandse Publieke Omroep. Retrieved 5 February 2015.
  12. ^ O'Malley, Charles Donald. Andreas Vesalius of Brussels, 1514–1564. Berkeley : University of California Press, 1964. p. 311.
  13. ^ See C.D. O'Malley Andreas Vesalius' Pilgrimage, Isis 45:2, 1954
  14. ^ O'Malley, C. Donald (1 January 1954). Andreas Vesalius' Pilgrimage. Isis. Vol. 45/2. pp. 138–144.
  15. ^ Kusukawa, Sachiko. "De humani corporis fabrica. Epitome". Cambridge Digital Library. Retrieved 3 July 2014.
  16. ^ Vallejo-Manzur F. et al. (2003) "The resuscitation greats. Andreas Vesalius, the concept of an artificial airway." "Resuscitation" 56:3–7
  17. ^ Andreas Vesalius, De humani corporis fabrica (1544), Book II, Ch. 24, 268. Trans. William Frank Rich son, On the Fabric of the Human Body (1999), Book II, 234. As quoted by W. F. Bynum & Roy Porter (2005), Oxford Dictionary of Scientific Quotations: Andreas Vesalius, 595:2, ISBN 0-19-858409-1.
  18. ^ Michael Servetus Research 13 November 2012 at the Wayback Machine Website with graphical study on the Manuscript of Paris by Servetus
  19. ^ The Anatomical Plates of Pietro da Cortona, Dover, New York, 1986. They were published in the 18th century. Twenty of the drawings for these plates are now in the Hunterian Library, Glasgow.
  20. ^ Burkhardt, Lotte (2022). Eine Enzyklopädie zu eponymischen Pflanzennamen [Encyclopedia of eponymic plant names] (pdf) (in German). Berlin: Botanic Garden and Botanical Museum, Freie Universität Berlin. doi:10.3372/epolist2022. ISBN 978-3-946292-41-8. Retrieved 27 January 2022.

Sources

  • Dear, Peter. Revolutionizing the Sciences: European Knowledge and Its Ambitions, 1500–1700. Princeton: Princeton UP, 2001.
  • Debus, Allen, ed. Vesalius. Who's Who in the World of Science: From Antiquity to Present. 1st ed. Hanibal: Western Co., 1968.
  • O'Malley, CD. Andreas Vesalius of Brussels, 1514–1564. Berkeley: University of California Press, 1964.
  • Porter, Roy, ed. Vesalius. The Biographical Dictionary of Scientists. 2nd Ed. New York: Oxford University P, 1994.
  • Saunders, JB de CM and O'Malley, Charles D. The Illustrations from the Works of Andreas Vesalius of Brussels. New York: Dover, 1973 [reprint].
  • "Vesalius." Encyclopedia Americana. 1992.
  • Vesalius, Andreas. On the Fabric of the Human Body, translated by W. F. Richardson and J. B. Carman. 5 vols. San Francisco and Novato: Norman Publishing, 1998–2009. The Fabric of the human Body, Translated by Daniel H. Garrison and Malcolm H. Hast. Basel: Karger Publishing, 2013. Garrison, Daniel H. Vesalius: The China Root Epistle. A New Translation and Critical Edition. New York: Cambridge University Press, 2014.
  • Williams, Trevor, ed. Vesalius. A Biographical Dictionary of Scientists. 3rd Ed. New York: John Wiley and Sons, 1982.

External links

  • Andreae Vesalii Bruxellensis, Dе humani corporis fabrica libri septem, Basileae 1543
  • Anatomia 1522–1867: Anatomical Plates from the Thomas Fisher Rare Book Library
  • Bibliography van Andreas Vesalius
  • Places and memories related to Andreas Vesalius
  • Play on Vesalius
  • Translating Vesalius
  • Ars Anatomica collection at University of Edinburgh image service (includes Vesalius's De Humanis Corporis Fabrica)
  • : a virtual copy of Vesalius's De Humanis Corporis Fabrica. From the U.S. National Library of Medicine.
  • De humani corporis fabrica. Epitome coloured and complete with manekin at Cambridge Digital Library
  • Texts digitized by the Bibliothèque interuniversitaire de santé; see its digital library .
  • Vesalius four centuries later by John F. Fulton. Logan Clendening lecture on the history and philosophy of medicine, University of Kansas, 1950. Full-text PDF.
  • Andreas Vesalius, VESALIUS project. Information about the new DVD "De Humani Corporis Fabrica" produced by Health Science Library of the St. Anna Hospital in Ferrara – Italy.
  • Vesalius College in Brussels
  • TV report on 500th birthday Vesalius by tvbrussel
  • De Humani Corporis Fabrica Libri Septem (1543) – full digital facsimile at Linda Hall Library
  • Vesalius at 500 – digital exhibition from the University of Missouri Libraries
  • Andreas Vesalius at the Mathematics Genealogy Project

andreas, vesalius, lunar, impact, crater, vesalius, crater, latinized, from, andries, wezel, december, 1514, october, 1564, 16th, century, anatomist, physician, author, most, influential, books, human, anatomy, humani, corporis, fabrica, libri, septem, fabric,. For the lunar impact crater see Vesalius crater Andreas Vesalius Latinized from Andries van Wezel v ɪ ˈ s eɪ l i e s 2 31 December 1514 15 October 1564 was a 16th century anatomist physician and author of one of the most influential books on human anatomy De Humani Corporis Fabrica Libri Septem On the fabric of the human body in seven books Vesalius is often referred to as the founder of modern human anatomy He was born in Brussels which was then part of the Habsburg Netherlands He was a professor at the University of Padua 1537 1542 and later became Imperial physician at the court of Emperor Charles V Andreas VesaliusPortrait by Jan van CalcarBornAndries van Wezel31 December 1514Brussels Habsburg Netherlands modern day Belgium Died15 October 1564 1564 10 15 aged 49 Zakynthos Venetian Ionian Islands modern day Greece EducationUniversity of Leuven M D 1537 University of ParisKnown forDe humani corporis fabrica On the Fabric of the Human Body Scientific careerFieldsAnatomyInstitutionsUniversity of Padua 1537 1542 ThesisParaphrasis in nonum librum Rhazae medici Arabis clarissimi ad regem Almansorem de affectuum singularum corporis partium curatione 1537 Academic advisorsJohann Winter von Andernach 1 Jacques Dubois 1 Jean Fernel 1 Notable studentsJohn CaiusRealdo ColomboGabriele FalloppioInfluencesGalenGemma FrisiusJohannes Baptista MontanusSignatureAndreas Vesalius is the Latinized form of the Dutch name Andries van Wesel It was a common practice among European scholars in his time to Latinize their names His name is also given as Andrea Vesalius Andre Vesale Andrea Vesalio Andreas Vesal Andres Vesalio and Andre Vesale Contents 1 Early life and education 2 Medical career and accomplishments 3 Imperial physician and death 4 Publications 4 1 De Humani Corporis Fabrica 4 1 1 Excerpts 4 2 Other publications 5 Scientific findings 5 1 Skeletal system 5 2 Muscular system 5 3 Vascular and circulatory systems 5 4 Nervous system 5 5 Abdominal organs 5 6 Heart 5 7 Other achievements 6 Scientific and historical impact 7 See also 8 References 9 Sources 10 External linksEarly life and education EditVesalius was born as Andries van Wesel to his father Anders van Wesel and mother Isabel Crabbe on 31 December 1514 in Brussels which was then part of the Habsburg Netherlands His great grandfather Jan van Wesel probably born in Wesel received a medical degree from the University of Pavia and taught medicine at the University of Leuven His grandfather Everard van Wesel was the Royal Physician of Emperor Maximilian whilst his father Anders van Wesel served as apothecary to Maximilian and later valet de chambre to his successor Charles V Anders encouraged his son to continue in the family tradition and enrolled him in the Brethren of the Common Life in Brussels to learn Greek and Latin prior to learning medicine according to standards of the era 3 In 1528 Vesalius entered the University of Leuven Pedagogium Castrense taking arts but when his father was appointed as the Valet de Chambre in 1532 he decided instead to pursue a career in the military at the University of Paris where he moved in 1533 There he studied the theories of Galen under the auspices of Johann Winter von Andernach Jacques Dubois Jacobus Sylvius and Jean Fernel It was during that time that he developed an interest in anatomy and was often found examining excavated bones in the charnel houses at the Cemetery of the Innocents Vesalius was forced to leave Paris in 1536 owing to the opening of hostilities between the Holy Roman Empire and France and returned to the University of Leuven He completed his studies there and graduated the following year His doctoral thesis Paraphrasis in nonum librum Rhazae medici Arabis clarissimi ad regem Almansorem de affectuum singularum corporis partium curatione was a commentary on the ninth book of Rhazes Medical career and accomplishments EditOn the day of his graduation he was immediately offered the chair of surgery and anatomy explicator chirurgiae at the University of Padua He also guest lectured at the University of Bologna and the University of Pisa Prior to taking up his position in Padua Vesalius traveled through Italy and assisted the future Pope Paul IV and Ignatius of Loyola to heal those afflicted by leprosy In Venice in 1542 he met the illustrator Johan van Calcar a student of Titian It was with van Calcar that Vesalius published his first anatomical text Tabulae Anatomicae Sex in 1538 4 Previously these topics had been taught primarily from reading classical texts mainly Galen followed by an animal dissection by a barber surgeon whose work was directed by the lecturer No attempt was made to confirm Galen s claims which were considered unassailable Vesalius in contrast performed dissection as the primary teaching tool handling the actual work himself and urging students to perform dissection themselves He considered hands on direct observation to be the only reliable resource Vesalius created detailed illustrations of anatomy for students in the form of six large woodcut posters When he found that some of them were being widely copied he published them all in 1538 under the title Tabulae anatomicae sex He followed this in 1539 with an updated version of Winter s anatomical handbook Institutiones anatomicae In 1539 he also published his Venesection Epistle on bloodletting This was a popular treatment for almost any illness but there was some debate about where to take the blood from The classical Greek procedure advocated by Galen was to collect blood from a site near the location of the illness However the Muslim and medieval practice was to draw a smaller amount of blood from a distant location Vesalius pamphlet generally supported Galen s view but with qualifications that rejected the infiltration of Galen In 1541 while in Bologna Vesalius discovered that all of Galen s research was restricted to animals since dissection had been banned in ancient Rome citation needed Galen had dissected Barbary macaques instead which he considered structurally closest to man Even though Galen produced many errors owing to the anatomical material available to him he was a qualified examiner but his research was weakened by stating his findings philosophically so his findings were based on religious precepts rather than science 5 Vesalius contributed to the new Giunta edition of Galen s collected works and began to write his own anatomical text based on his own research Until Vesalius pointed out Galen s substitution of animal for human anatomy it had gone unnoticed and had long been the basis of studying human anatomy However some people still chose to follow Galen and resented Vesalius for calling attention to the difference Galen had assumed that arteries carried the purest blood to higher organs such as the brain and lungs from the left ventricle of the heart while veins carried blood to the lesser organs such as the stomach from the right ventricle In order for this theory to be correct some kind of opening was needed to interconnect the ventricles and Galen claimed to have found them So paramount was Galen s authority that for 1400 years a succession of anatomists had claimed to find these holes until Vesalius admitted he could not find them Nonetheless he did not venture to dispute Galen on the distribution of blood being unable to offer any other solution and so supposed that it diffused through the unbroken partition between the ventricles 6 Other famous examples of Vesalius disproving Galen s assertions were his discoveries that the lower jaw mandible was composed of only one bone not two which Galen had assumed based on animal dissection and that humans lack the rete mirabile a network of blood vessels at the base of the brain that is found in sheep and other ungulates The skeleton of Jakob Karrer articulated by Vesalius in 1543 In 1543 Vesalius conducted a public dissection of the body of Jakob Karrer von Gebweiler a notorious felon from the city of Basel Switzerland He assembled and articulated the bones finally donating the skeleton to the University of Basel This preparation The Basel Skeleton is Vesalius only well preserved skeletal preparation and also the world s oldest surviving anatomical preparation It is still displayed at the Anatomical Museum of the University of Basel 7 In the same year Vesalius took residence in Basel to help Johannes Oporinus publish the seven volume De humani corporis fabrica On the fabric of the human body a groundbreaking work of human anatomy that he dedicated to Charles V Many believe it was illustrated by Titian s pupil Jan Stephen van Calcar but evidence is lacking and it is unlikely that a single artist created all 273 illustrations in a period of time so short At about the same time he published an abridged edition for students Andrea Vesalii suorum de humani corporis fabrica librorum epitome and dedicated it to Philip II of Spain the son of the Emperor That work now collectively referred to as the Fabrica of Vesalius was groundbreaking in the history of medical publishing and is considered to be a major step in the development of scientific medicine Because of this it marks the establishment of anatomy as a modern descriptive science 8 Though Vesalius work was not the first such work based on actual dissection nor even the first work of this era the production quality highly detailed and intricate plates and the likelihood that the artists who produced it were clearly present in person at the dissections made it an instant classic Pirated editions were available almost immediately an event Vesalius acknowledged in a printer s note would happen Vesalius was 28 years old when the first edition of Fabrica was published Imperial physician and death Edit The Holy Roman Emperor Charles V who was an important patron of Vesalius Soon after publication Vesalius was invited to become imperial physician to the court of Emperor Charles V He informed the Venetian Senate that he would leave his post at Padua which prompted Duke Cosimo I de Medici to invite him to move to the expanding university in Pisa which he declined Vesalius took up the offered position in the imperial court where he had to deal with other physicians who mocked him for being a mere barber surgeon instead of an academic working on the respected basis of theory In the 1540s shortly after entering in service of the emperor Vesalius married Anne van Hamme from Vilvorde Belgium They had one daughter named Anne who died in 1588 9 Over the next eleven years Vesalius traveled with the court treating injuries caused in battle or tournaments performing postmortems administering medication and writing private letters addressing specific medical questions During these years he also wrote the Epistle on the China root a short text on the properties of a medical plant whose efficacy he doubted as well as a defense of his anatomical findings This elicited a new round of attacks on his work that called for him to be punished by the emperor In 1551 Charles V commissioned an inquiry in Salamanca to investigate the religious implications of his methods Although Vesalius work was cleared by the board the attacks continued Four years later one of his main detractors and one time professors Jacobus Sylvius published an article that claimed that the human body itself had changed since Galen had studied it In 1555 Vesalius became physician to Philip II 10 and in the same year he published a revised edition of De humani corporis fabrica In 1564 Vesalius went on a pilgrimage to the Holy Land some said in penance after being accused of dissecting a living body He sailed with the Venetian fleet under James Malatesta via Cyprus When he reached Jerusalem he received a message from the Venetian senate requesting him again to accept the Paduan professorship which had become vacant on the death of his friend and pupil Fallopius After struggling for many days with adverse winds in the Ionian Sea he was shipwrecked on the island of Zakynthos 11 Here he soon died in such debt that a benefactor kindly paid for his funeral At the time of his death he was 49 years old He was buried somewhere on the island of Zakynthos Zante 12 For some time it was assumed that Vesalius s pilgrimage was due to the pressures imposed on him by the Inquisition Today this assumption is generally considered to be without foundation 13 and is dismissed by modern biographers It appears the story was spread by Hubert Languet a diplomat under Emperor Charles V and then under the Prince of Orange who claimed in 1565 that Vesalius had performed an autopsy on an aristocrat in Spain while the heart was still beating leading to the Inquisition s condemning him to death The story went on to claim that Philip II had the sentence commuted to a pilgrimage That story re surfaced several times until it was more recently revised The decision to undertake the pilgrimage was likely just a pretext to leave the Spanish court Its lifestyle did not please him and he longed to continue his research Given that he could not get rid of his royal service by resignation he managed to escape asking for the permission to go to Jerusalem 14 Publications EditDe Humani Corporis Fabrica Edit A portrait of Vesalius from his De Humani Corporis Fabrica 1543 Main article De Humani Corporis Fabrica Libri Septem In 1543 Vesalius asked Johannes Oporinus to publish the book De Humani Corporis Fabrica Libri Septem On the fabric of the human body in seven books a groundbreaking work of human anatomy he dedicated to Charles V and which many believe was illustrated by Titian s pupil Jan Stephen van Calcar About the same time he published another version of his great work entitled De Humani Corporis Fabrica Librorum Epitome Abridgement of the On the fabric of the human body more commonly known as the Epitome with a stronger focus on illustrations than on text so as to help readers including medical students to easily understand his findings The actual text of the Epitome was an abridged form of his work in the Fabrica and the organization of the two books was quite varied He dedicated it to Philip II of Spain son of the Emperor 15 The Fabrica emphasized the priority of dissection and what has come to be called the anatomical view of the body seeing human internal functioning as a result of an essentially corporeal structure filled with organs arranged in three dimensional space His book contains drawings of several organs on two leaves This allows for the creation of three dimensional diagrams by cutting out the organs and pasting them on flayed figures 8 This was in stark contrast to many of the anatomical models used previously which had strong Galenic Aristotelean elements as well as elements of astrology Although modern anatomical texts had been published by Mondino and Berenger much of their work was clouded by reverence for Galen and Arabian doctrines Vesalius s Fabrica contained many intricately detailed drawings of human dissections often in allegorical poses Besides the first good description of the sphenoid bone he showed that the sternum consists of three portions and the sacrum of five or six and described accurately the vestibule in the interior of the temporal bone He not only verified Estienne s observations on the valves of the hepatic veins but also described the vena azygos and discovered the canal which passes in the fetus between the umbilical vein and the vena cava since named the ductus venosus He described the omentum and its connections with the stomach the spleen and the colon gave the first correct views of the structure of the pylorus observed the small size of the caecal appendix in man gave the first good account of the mediastinum and pleura and the fullest description of the anatomy of the brain up to that time He did not understand the inferior recesses and his account of the nerves is confused by regarding the optic as the first pair the third as the fifth and the fifth as the seventh In this work Vesalius also becomes the first person to describe mechanical ventilation 16 It is largely this achievement that has resulted in Vesalius being incorporated into the Australian and New Zealand College of Anaesthetists college arms and crest Excerpts Edit When I undertake the dissection of a human pelvis I pass a stout rope tied like a noose beneath the lower jaw and through the zygomas up to the top of the head The lower end of the noose I run through a pulley fixed to a beam in the room so that I may raise or lower the cadaver as it hangs there or turn around in any direction to suit my purpose You must take care not to put the noose around the neck unless some of the muscles connected to the occipital bone have already been cut away 17 Other publications Edit In 1538 Vesalius wrote Epistola docens venam axillarem dextri cubiti in dolore laterali secandam A letter teaching that in cases of pain in the side the axillary vein of the right elbow be cut commonly known as the Venesection Letter which demonstrated a revived venesection a classical procedure in which blood was drawn near the site of the ailment He sought to locate the precise site for venesection in pleurisy within the framework of the classical method The real significance of the book is his attempt to support his arguments by the location and continuity of the venous system from his observations rather than appeal to earlier published works With this novel approach to the problem of venesection Vesalius posed the then striking hypothesis that anatomical dissection might be used to test speculation In 1546 three years after the Fabrica he wrote his Epistola rationem modumque propinandi radicis Chynae decocti commonly known as the Epistle on the China Root Ostensibly an appraisal of a popular but ineffective treatment for gout syphilis and stones this work is especially important as a continued polemic against Galenism and a reply to critics in the camp of his former professor Jacobus Sylvius now an obsessive detractor In February 1561 Vesalius was given a copy of Gabriele Fallopio s Observationes anatomicae friendly additions and corrections to the Fabrica Before the end of the year Vesalius composed a cordial reply Anatomicarum Gabrielis Fallopii observationum examen generally referred to as the Examen In this work he recognizes in Fallopio a true equal in the science of dissection he had done so much to create Vesalius reply to Fallopio was published in May 1564 a month after Vesalius death on the Greek island of Zante now called Zakynthos Scientific findings EditSkeletal system Edit Vesalius believed the skeletal system to be the framework of the human body It was in this opening chapter or book of De fabrica that Vesalius made several of his strongest claims against Galen s theories and writings which he had put in his anatomy books In his extensive study of the skull Vesalius claimed that the mandible consisted of one bone whereas Galen had thought it to be two separate bones He accurately described the vestibule in the interior of the temporal bone of the skull In Galen s observation of the ape he had discovered that their sternum consisted of seven parts which he assumed also held true for humans Vesalius discovered that the human sternum consisted of only three parts He also disproved the common belief that men had one rib fewer than women and noted that the fibula and tibia bones of the leg were indeed larger than the humerus bone of the arm unlike Galen s original findings Muscular system Edit Vesalius most impressive contribution to the study of the muscular system may be the illustrations that accompany the text in De fabrica which would become known as the muscle men He describes the source and position of each muscle of the body and provides information on their respective operation Vascular and circulatory systems Edit Vesalius work on the vascular and circulatory systems was his greatest contribution to modern medicine In his dissections of the heart Vesalius became convinced that Galen s claims of a porous interventricular septum were false This fact was previously described by Michael Servetus a fellow of Vesalius but never reached the public for it was written down in the Manuscript of Paris 18 in 1546 and published later in his Christianismi Restitutio 1553 a book regarded as heretical by the Inquisition Only three copies survived but these remained hidden for decades the rest having been burned shortly after publication In the second edition Vesalius published that the septum was indeed waterproof discovering and naming the mitral valve to explain the blood flow Vesalius believed that cardiac systole is synchronous with the arterial pulse He not only verified Estienne s findings on the valves of the hepatic veins but also described the azygos vein and discovered the canal which passes into the fetus between the umbilical vein and vena cava Nervous system Edit Vesalius defined a nerve as the mode of transmitting sensation and motion and thus refuted his contemporaries claims that ligaments tendons and aponeuroses were three types of nerve units He believed that the brain and the nervous system are the center of the mind and emotion in contrast to the common Aristotelian belief that the heart was the center of the body He correspondingly believed that nerves themselves do not originate from the heart but from the brain facts already experimentally proved by Herophilus and Erasistratus in the classical era but suppressed after the adoption of Aristotelianism by the Catholic Church in the Middle Ages Upon studying the optic nerve Vesalius came to the conclusion that nerves were not hollow Abdominal organs Edit In De fabrica he corrected an earlier claim he made in Tabulae about the right kidney being set higher than the left Vesalius claimed that the kidneys were not a filter device for urine to pass through but rather that the kidneys serve to filter blood as well and that excretions from the kidneys travelled through the ureters to the bladder He described the omentum and its connections with the stomach the spleen and the colon gave the first correct views of the structure of the pylorus He also observed the small size of the caecal appendix in man and gave the first good account of the mediastinum and pleura Vesalius admitted that due to a lack of pregnant cadavers he was unable to come to a significant understanding of the reproductive organs However he did find that the uterus had been falsely identified as having two distinct sections Heart Edit Through his work with muscles Vesalius believed that a criterion for muscles was their voluntary motion On this claim he deduced that the heart was not a true muscle due to the obvious involuntary nature of its motion He identified two chambers and two atria The right atrium was considered a continuation of the inferior and superior venae cavae and the left atrium was considered a continuation of the pulmonary vein He also addressed the controversial issue of the heart being the centre of the soul He wished to avoid drawing any conclusions due to possible conflict with contemporary religious beliefs Base of the brain showing the optic chiasma cerebellum olfactory bulbs etc Against Galen s theory and many beliefs he also discovered that there was no hole in the septum or heart Other achievements Edit Vesalius disproved Galen s assertion that men have more teeth than women 11 Vesalius introduced the notion of induction of the extraction of empyema through surgical means Due to his impressive study of the human skull and the variations in its features he is said to have been responsible for the launch of the study of physical anthropology Vesalius always encouraged his students to check their findings and even his own findings so that they could better understand the structure of the human body In addition to his continual efforts to study anatomy he also worked on medicinal remedies and came to such conclusions as treating syphilis with chinaroot Vesalius claimed that medicine had three aspects drugs diet and the use of hands mainly suggesting surgery and the knowledge of anatomy and physiology gained through dissection Vesalius was a supporter of parallel dissections in which an animal cadaver and a human cadaver are dissected simultaneously in order to demonstrate the anatomical differences and thus correct Galenic errors Scientific and historical impact EditThe influence of Vesalius plates representing the partial dissections of the human figure posing in a landscape setting is apparent in the anatomical plates prepared by the Baroque painter Pietro da Cortona 1596 1669 who executed anatomical plates with figures in dramatic poses most of them with architectural or landscape backdrops 19 In 1844 botanists Martin Martens and Henri Guillaume Galeotti published Vesalea which is a plant genus in the honeysuckle family Caprifoliaceae and it was named in Vesalius s honour 20 See also EditAndrotomy Brain Renaissance InVesalius Medical Renaissance Physician writer Timeline of medicine and medical technology Vesalius CollegeReferences Edit Wikiquote has quotations related to Andreas Vesalius a b c Andreas Vesalius of Brussels 1514 1564 Charles Donald O Malley Wellcome Collection University of California Press 1964 p 47 OCLC 429258 Archived from the original on 23 February 2022 Retrieved 23 February 2022 Vesalius Dictionary com www dictionary com Archived from the original on 23 February 2022 Retrieved 23 February 2022 O Malley Charles Donald Andreas Vesalius of Brussels 1514 1564 Berkeley University of California Press 1964 pp 21 27 Vesalius at 500 The Physician s Palette Archived from the original on 10 December 2014 O Malley Charles Donald Andreas Vesalius of Brussels 1514 1564 Berkeley University of California Press 1964 Bonnier Corporation May 1872 Popular Science The Popular Science Monthly Bonnier Corporation 95 100 ISSN 0161 7370 Archived copy PDF Archived from the original PDF on 27 September 2007 Retrieved 10 October 2009 a href Template Cite web html title Template Cite web cite web a CS1 maint archived copy as title link a b Harcourt Glenn 1 January 1987 Andreas Vesalius and the Anatomy of Antique Sculpture Representations 17 17 28 61 doi 10 2307 3043792 ISSN 0734 6018 JSTOR 3043792 PMID 11618035 O Malley Charles Donald Andreas Vesalius of Brussels 1514 1564 Berkeley University of California Press 1964 pp 203 314 Andreas Vesalius 1514 1564 BBC History Retrieved 14 March 2022 a b Lambert Teuwissen 31 December 2014 Vesalius was belangrijker dan Copernicus in Dutch Nederlandse Publieke Omroep Retrieved 5 February 2015 O Malley Charles Donald Andreas Vesalius of Brussels 1514 1564 Berkeley University of California Press 1964 p 311 See C D O Malley Andreas Vesalius Pilgrimage Isis 45 2 1954 O Malley C Donald 1 January 1954 Andreas Vesalius Pilgrimage Isis Vol 45 2 pp 138 144 Kusukawa Sachiko De humani corporis fabrica Epitome Cambridge Digital Library Retrieved 3 July 2014 Vallejo Manzur F et al 2003 The resuscitation greats Andreas Vesalius the concept of an artificial airway Resuscitation 56 3 7 Andreas Vesalius De humani corporis fabrica 1544 Book II Ch 24 268 Trans William Frank Rich son On the Fabric of the Human Body 1999 Book II 234 As quoted by W F Bynum amp Roy Porter 2005 Oxford Dictionary of Scientific Quotations Andreas Vesalius 595 2 ISBN 0 19 858409 1 Michael Servetus Research Archived 13 November 2012 at the Wayback Machine Website with graphical study on the Manuscript of Paris by Servetus The Anatomical Plates of Pietro da Cortona Dover New York 1986 They were published in the 18th century Twenty of the drawings for these plates are now in the Hunterian Library Glasgow Burkhardt Lotte 2022 Eine Enzyklopadie zu eponymischen Pflanzennamen Encyclopedia of eponymic plant names pdf in German Berlin Botanic Garden and Botanical Museum Freie Universitat Berlin doi 10 3372 epolist2022 ISBN 978 3 946292 41 8 Retrieved 27 January 2022 Sources EditDear Peter Revolutionizing the Sciences European Knowledge and Its Ambitions 1500 1700 Princeton Princeton UP 2001 Debus Allen ed Vesalius Who s Who in the World of Science From Antiquity to Present 1st ed Hanibal Western Co 1968 O Malley CD Andreas Vesalius of Brussels 1514 1564 Berkeley University of California Press 1964 Porter Roy ed Vesalius The Biographical Dictionary of Scientists 2nd Ed New York Oxford University P 1994 Saunders JB de CM and O Malley Charles D The Illustrations from the Works of Andreas Vesalius of Brussels New York Dover 1973 reprint Vesalius Encyclopedia Americana 1992 Vesalius Andreas On the Fabric of the Human Body translated by W F Richardson and J B Carman 5 vols San Francisco and Novato Norman Publishing 1998 2009 The Fabric of the human Body Translated by Daniel H Garrison and Malcolm H Hast Basel Karger Publishing 2013 Garrison Daniel H Vesalius The China Root Epistle A New Translation and Critical Edition New York Cambridge University Press 2014 Williams Trevor ed Vesalius A Biographical Dictionary of Scientists 3rd Ed New York John Wiley and Sons 1982 External links Edit Wikimedia Commons has media related to Andreas Vesalius Andreae Vesalii Bruxellensis De humani corporis fabrica libri septem Basileae 1543 Anatomia 1522 1867 Anatomical Plates from the Thomas Fisher Rare Book Library Bibliography van Andreas Vesalius Vesalius s Anatomies Introduction by Jacqueline Vons Places and memories related to Andreas Vesalius Play on Vesalius Translating Vesalius Ars Anatomica collection at University of Edinburgh image service includes Vesalius s De Humanis Corporis Fabrica Turning the Pages a virtual copy of Vesalius s De Humanis Corporis Fabrica From the U S National Library of Medicine De humani corporis fabrica Epitome coloured and complete with manekin at Cambridge Digital Library Texts digitized by the Bibliotheque interuniversitaire de sante see its digital library Medic Vesalius four centuries later by John F Fulton Logan Clendening lecture on the history and philosophy of medicine University of Kansas 1950 Full text PDF Andreas Vesalius VESALIUS project Information about the new DVD De Humani Corporis Fabrica produced by Health Science Library of the St Anna Hospital in Ferrara Italy Vesalius College in Brussels TV report on 500th birthday Vesalius by tvbrussel De Humani Corporis Fabrica Libri Septem 1543 full digital facsimile at Linda Hall Library Vesalius at 500 digital exhibition from the University of Missouri Libraries Andreas Vesalius at the Mathematics Genealogy Project Retrieved from https en wikipedia org w index php title Andreas Vesalius amp oldid 1131155612, wikipedia, wiki, book, books, library,

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