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2-Amino-3-carboxymuconic semialdehyde

2-Amino-3-carboxymuconic semialdehyde[1][2] is an intermediate in the metabolism of tryptophan in the tryptophan-niacin catabolic pathway. Quinolinate is a neurotoxin formed nonenzymatically from 2-amino-3-carboxymuconic semialdehyde in mammalian tissues. 2-Amino-3-carboxymuconic semialdehyde is enzymatically converted to 2-aminomuconate via 2-aminomuconic semialdehyde.

2-Amino-3-carboxymuconic semialdehyde
Names
Preferred IUPAC name
(2Z)-2-Amino-3-[(1Z)-3-oxoprop-1-en-1-yl]but-2-enedioic acid
Identifiers
  • 16597-58-3 N
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:994 Y
ChemSpider
  • 7822292 Y
  • 5280673
  • DTXSID10274255
  • InChI=1S/C7H7NO5/c8-5(7(12)13)4(6(10)11)2-1-3-9/h1-3H,8H2,(H,10,11)(H,12,13)/p-2/b2-1-,5-4- Y
    Key: KACPVQQHDVBVFC-OIFXTYEKSA-L Y
  • C(=C/C(=C(\C(=O)O)/N)/C(=O)O)/C=O
Properties
C7H7NO5
Molar mass 185.13 g/mol
Density 1.527 g/mL
Boiling point 389 °C (732 °F; 662 K)
Hazards
Flash point 189 °C (372 °F; 462 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)

References Edit

  1. ^ "UniProt". www.uniprot.org. Retrieved 2022-11-22.
  2. ^ "Human Metabolome Database: Showing metabocard for 2-Amino-3-carboxymuconic acid semialdehyde (HMDB0001330)". hmdb.ca. Retrieved 2022-11-22.


amino, carboxymuconic, semialdehyde, intermediate, metabolism, tryptophan, tryptophan, niacin, catabolic, pathway, quinolinate, neurotoxin, formed, nonenzymatically, from, amino, carboxymuconic, semialdehyde, mammalian, tissues, enzymatically, converted, amino. 2 Amino 3 carboxymuconic semialdehyde 1 2 is an intermediate in the metabolism of tryptophan in the tryptophan niacin catabolic pathway Quinolinate is a neurotoxin formed nonenzymatically from 2 amino 3 carboxymuconic semialdehyde in mammalian tissues 2 Amino 3 carboxymuconic semialdehyde is enzymatically converted to 2 aminomuconate via 2 aminomuconic semialdehyde 2 Amino 3 carboxymuconic semialdehyde NamesPreferred IUPAC name 2Z 2 Amino 3 1Z 3 oxoprop 1 en 1 yl but 2 enedioic acidIdentifiersCAS Number 16597 58 3 N3D model JSmol Interactive imageChEBI CHEBI 994 YChemSpider 7822292 YPubChem CID 5280673CompTox Dashboard EPA DTXSID10274255InChI InChI 1S C7H7NO5 c8 5 7 12 13 4 6 10 11 2 1 3 9 h1 3H 8H2 H 10 11 H 12 13 p 2 b2 1 5 4 YKey KACPVQQHDVBVFC OIFXTYEKSA L YSMILES C C C C C O O N C O O C OPropertiesChemical formula C 7H 7N O 5Molar mass 185 13 g molDensity 1 527 g mLBoiling point 389 C 732 F 662 K HazardsFlash point 189 C 372 F 462 K Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa N verify what is Y N Infobox referencesReferences Edit UniProt www uniprot org Retrieved 2022 11 22 Human Metabolome Database Showing metabocard for 2 Amino 3 carboxymuconic acid semialdehyde HMDB0001330 hmdb ca Retrieved 2022 11 22 This article about an alkene is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 2 Amino 3 carboxymuconic semialdehyde amp oldid 1145539171, wikipedia, wiki, book, books, library,

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