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Svante Pääbo

January 26, 2023

Svante Pääbo ForMemRS (Swedish: [ˈsvânːtɛ̂ ˈpʰɛ̌ːbʊ̂];[3] born 20 April 1955) is a Swedish geneticist and Nobel Laureate who specialises in the field of evolutionary genetics.[4] As one of the founders of paleogenetics, he has worked extensively on the Neanderthal genome.[5][6] In 1997, he became founding director of the Department of Genetics at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.[7][8][9] Since 1999, he has been an honorary professor at Leipzig University; he currently teaches molecular evolutionary biology at the university.[10][11] He is also an adjunct professor at Okinawa Institute of Science and Technology, Japan.[12]

Svante Pääbo

ForMemRS
Pääbo in 2016
Born (1955-04-20) 20 April 1955 (age 67)
Stockholm, Sweden
EducationUppsala University (PhD)
Known forPaleogenetics
Spouse
​
(m. 2008)​
Children2
RelativesSune Bergström (father)
Awards
Scientific career
Fields
Institutions
ThesisHow the E19 Protein of Adenoviruses Modulates the Immune System (1986)

In 2022, he was awarded the Nobel Prize in Physiology or Medicine "for his discoveries concerning the genomes of extinct hominins and human evolution".[13][14][15]

Education and early life

Pääbo was born in Stockholm, Sweden in 1955 and grew up there with his mother,[5] Estonian chemist Karin Pääbo (Estonian: [ˈpæːbo]; 1925–2013), who had escaped from the Soviet invasion in 1944[16] and arrived in Sweden as a refugee during World War II.[17][18] He was born through a secret extramarital affair[19] of his father, Swedish biochemist Sune Bergström (1916–2004),[5] who, like his son, became a recipient of the Nobel Prize in Physiology or Medicine (in 1982).[20] Pääbo is his mother's only child; he has via his father's marriage a half-brother (also born in 1955).[21]

Pääbo grew up as a native Swedish speaker.[22] In a 2012 interview with the Estonian newspaper Eesti Päevaleht, he said that he self-identifies as a Swede, but has a "special relationship with Estonia".[23]

In 1975, Pääbo began studying at Uppsala University, serving one year in the Swedish Defense Forces attached to the School of Interpreters. Pääbo earned his Ph.D. from Uppsala University in 1986 for research investigating how the E19 protein of adenoviruses modulates the immune system.[24]

Research and career

 
Pääbo at the 2014 Nobel Conference

Pääbo is known as one of the founders of paleogenetics, a discipline that uses genetics to study early humans and other ancient species.[25][26]

From 1986 to 1987, he did postdoctoral research at the Institute for Molecular Biology II, University of Zurich, Switzerland.[27]

As an EMBO Postdoctoral Fellow, Pääbo moved to the United States in 1987, accepting a position as a postdoctoral researcher in biochemistry at the University of California, Berkeley, where he joined Allan Wilson's lab and worked on the genome of extinct mammals.[27][28]

In 1990, he returned to Europe to become professor of general biology at the University of Munich, and, in 1997, he became founding director of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.[28]

In 1997, Pääbo and colleagues reported their successful sequencing of Neanderthal mitochondrial DNA (mtDNA), originating from a specimen found in Feldhofer grotto in the Neander valley.[29][30]

In August 2002, Pääbo's department published findings about the "language gene", FOXP2, which is mutated in some individuals with language disabilities.[31]

In 2006, Pääbo announced a plan to reconstruct the entire genome of Neanderthals. In 2007, he was named one of Time magazine's 100 most influential people of the year.[32]

In February 2009, at the Annual Meeting of the American Association for the Advancement of Science (AAAS) in Chicago, it was announced that the Max Planck Institute for Evolutionary Anthropology had completed the first draft version of the Neanderthal genome.[33] Over 3 billion base pairs were sequenced in collaboration with the 454 Life Sciences Corporation.[34]

In March 2010, Pääbo and his coworkers published a report about the DNA analysis of a finger bone found in the Denisova Cave in Siberia; the results suggest that the bone belonged to an extinct member of the genus Homo that had not yet been recognised, the Denisova hominin.[35] Pääbo first wanted to classify the Denisovans as a species of their own, separate from modern humans and Neanderthals but changed his mind after peer-review.[36][37]

Pääbo's doctoral student Viviane Slon was able to successfully map the Denisovan genome, clarifying geographic distribution and admixtures in archaic humans.[38][39]

In May 2010, Pääbo and his colleagues published a draft sequence of the Neanderthal genome in the journal Science.[40] He and his team also concluded that there was probably interbreeding between Neanderthals and Eurasian (but not Sub-Saharan African) humans.[41] There is general mainstream support in the scientific community for this theory of interbreeding between archaic and modern humans.[42] This admixture of modern human and Neanderthal genes is estimated to have occurred roughly between 50,000 and 60,000 years ago, in the Middle East.[43]

In 2014, he published the book Neanderthal Man: In Search of Lost Genomes where he, in the mixed form of a memoir and popular science, tells the story of the research effort to map the Neanderthal genome combined with his thoughts on human evolution.[20][44]

In 2020, Pääbo determined that more severe impacts upon victims of the COVID-19 disease, including the vulnerability to it and the incidence of the necessity of hospitalisation, have been associated via DNA analysis to be expressed in genetic variants at chromosomal region 3, features that are associated with European Neanderthal heritage. That structure imposes greater risks that those affected will develop a more severe form of the disease.[45] The findings are from Pääbo and researchers he leads at the Planck Institute and the Karolinska Institutet.[45]

As of October 2022, Pääbo has an h-index of 167 according to Google Scholar[4] and of 133 according to Scopus.[46]

Awards and honours

In 1992, he received the Gottfried Wilhelm Leibniz Prize of the Deutsche Forschungsgemeinschaft, which is the highest honour awarded in German research. Pääbo was elected a member of the Royal Swedish Academy of Sciences in 2000, and in 2004 was elected an international member of the National Academy of Sciences.[47] In 2005, he received the prestigious Louis-Jeantet Prize for Medicine.[1] In 2008, Pääbo was added to the members of the Order Pour le Mérite for Sciences and Arts. In the same year, he received the Golden Plate Award of the American Academy of Achievement.[48] In October 2009, the Foundation For the Future announced that Pääbo had been awarded the 2009 Kistler Prize for his work isolating and sequencing ancient DNA, beginning in 1984 with a 2,400-year-old mummy.[49] In June 2010, the Federation of European Biochemical Societies (FEBS) awarded him the Theodor Bücher Medal for outstanding achievements in Biochemistry and Molecular Biology.[50] In 2013, he received Gruber Prize in Genetics for groundbreaking research in evolutionary genetics.[51] In June 2015, he was awarded the degree of DSc (honoris causa) at NUI Galway.[52] He was elected a Foreign Member of the Royal Society in 2016,[2] and in 2017, was awarded the Dan David Prize. In 2018, he received the Princess of Asturias Awards in the category of Scientific Research, in 2020 the Japan Prize,[53] in 2021 the Massry Prize[54] and in 2022 the Nobel Prize in Physiology or Medicine[55] for sequencing the first Neanderthal genome.[14]

Personal life

Pääbo wrote in his 2014 book Neanderthal Man: In Search of Lost Genomes that he is bisexual. He assumed he was gay until he met Linda Vigilant, an American primatologist and geneticist whose "boyish charms" attracted him. They have co-authored many papers, are married and raising a son and a daughter together in Leipzig.[56][6]

See also

References

  1. ^ a b "Professor Svante PÄÄBO | Jeantet". 1 October 2017. from the original on 16 May 2021. Retrieved 16 October 2021.
  2. ^ a b "Svante Paabo". London: Royal Society. 2016. from the original on 29 April 2016. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --"Royal Society Terms, conditions and policies". from the original on 25 September 2015. Retrieved 9 March 2016.
  3. ^ Lena Nordlund, Annlouise Martin (Producers) (14 August 2014). Svante Pääbo (MP3) (Radio). Sveriges Radio. Event occurs at 1:15. from the original on 3 October 2022. Retrieved 2 May 2018.
  4. ^ a b Svante Pääbo publications indexed by Google Scholar  
  5. ^ a b c Kolbert, Elizabeth. "Sleeping with the Enemy: What happened between the Neanderthals and us?". The New Yorker. No. 15 & 22 August 2011. pp. 64–75. from the original on 11 July 2022. Retrieved 23 November 2021.
  6. ^ a b Pääbo, Svante (2014). Neanderthal Man: In Search of Lost Genomes. Basic Books. ISBN 978-0-465-02083-6.
  7. ^ Gitschier, J. (2008). "Imagine: An Interview with Svante Pääbo". PLOS Genetics. PLOS. 4 (3): e1000035. doi:10.1371/journal.pgen.1000035. PMC 2274957. PMID 18369454.
  8. ^ Zagorski, N. (2006). "Profile of Svante Pääbo". Proceedings of the National Academy of Sciences of the United States of America. 103 (37): 13575–13577. Bibcode:2006PNAS..10313575Z. doi:10.1073/pnas.0606596103. PMC 1564240. PMID 16954182.
  9. ^ . Archived from the original on 19 July 2011. Retrieved 27 July 2011.
  10. ^ Heckmann, Carsten. "Honorary professor at Leipzig University recognised: Japan Prize Goes to Svante Pääbo". Leipzig University. eipzig University. Retrieved 17 October 2022.
  11. ^ Heckmann, Carsten. "Congratulations to our honorary professor! Nobel Prize for Savante Pääbo". Leipzig University. eipzig University. Retrieved 17 October 2022.
  12. ^ "Svante Pääbo". OIST Groups. 29 April 2020. from the original on 24 October 2021. Retrieved 3 October 2022.
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  14. ^ a b Grover, Natalie; Pollard, Niklas; Ahlander, Johan (3 October 2022). "Swedish geneticist wins Nobel medicine prize for decoding ancient DNA". Reuters. from the original on 3 October 2022. Retrieved 3 October 2022.
  15. ^ "Nobel laureate Svante Paabo's ancient DNA discoveries shed light on what makes us human". Onmanorama. 6 October 2022. from the original on 6 October 2022. Retrieved 6 October 2022.
  16. ^ Külli Riin Tigasson (17 March 2012). "Svante Pääbo: mis tegi inimesest inimese?" (Interview with subject). Eesti Päevaleht (in Estonian). Retrieved 20 October 2022.
  17. ^ Tambur, Silver (3 October 2022). "Estonian descendant Svante Pääbo awarded Nobel prize". EstonianWorld. from the original on 8 October 2022. Retrieved 8 October 2022.
  18. ^ Strandberg, Marek (4 October 2022). "Eesti juurtega Svante Pääbo tõi kärgperre teisegi Nobeli auhinna". Postimees (in Estonian). (subscription required)
  19. ^ Schultz, Isaac (3 October 2022). "Paleogeneticist Svante Pääbo Picks Up Nobel Prize for Human Origins Research". Gizmodo. from the original on 6 October 2022. Retrieved 6 October 2022.
  20. ^ a b Peter Forbes (20 February 2014) Neanderthal Man: In Search of Lost Genomes by Svante Pääbo – review 1 December 2021 at the Wayback Machine
  21. ^ "Svensken Svante Pääbo får Nobelpriset i medicin". Dagens Nyheter (in Swedish). 3 October 2022. from the original on 3 October 2022. Retrieved 3 October 2022.
  22. ^ Külli Riin Tigasson (17 March 2012). "Svante Pääbo: mis tegi inimesest inimese?" (Interview with subject). Eesti Päevaleht (in Estonian). Retrieved 20 October 2022.
  23. ^ Külli Riin Tigasson (17 March 2012). "Svante Pääbo: mis tegi inimesest inimese?" (Interview with subject). Eesti Päevaleht (in Estonian). Retrieved 20 October 2022. Pääbo was quoted saying: "I grew up understanding what Estonia is, but I don't speak Estonian. I have never attended Estonian school. I identify with the Swedes, but I have a special relationship with Estonia."(Kasvasin üles teades, mis on Eesti, aga eesti keelt ma ei räägi. Ma pole kunagi käinud eesti koolis. Identifitseerin end rootslastega, aga mul on eriline suhe Eestiga)
  24. ^ Pääbo, Svante (1986). How the E19 protein of adenoviruses modulates the immune system (PhD thesis). Uppsala University. ISBN 9155419216. OCLC 16668494. from the original on 3 October 2022. Retrieved 22 December 2016.
  25. ^ "Svante Paabo publications in PubMed". from the original on 3 October 2022. Retrieved 27 July 2011.
  26. ^ "Edge: Mapping the Neanderthal Genome – A Conversation With Svante Pääbo". from the original on 13 December 2012. Retrieved 27 July 2011.
  27. ^ a b "Svante Pääbo". Max Planch Institute. 3 October 2022. from the original on 6 October 2022. Retrieved 6 October 2022.
  28. ^ a b Daniela Mocker (4 October 2022). "Nobel Winner Svante Pääbo Discovered the Neandertal in Our Genes". Scientific American.
  29. ^ Krings, M; Stone, A; Schmitz, Rw; Krainitzki, H; Stoneking, M; Pääbo, S (1997). "Neandertal DNA sequences and the origin of modern humans". Cell. 90 (1): 19–30. doi:10.1016/S0092-8674(00)80310-4. hdl:11858/00-001M-0000-0025-0960-8. ISSN 0092-8674. PMID 9230299. S2CID 13581775.
  30. ^ Rincon, Paul (11 April 2018). "How ancient DNA is transforming our view of the past". BBC. from the original on 30 March 2019. Retrieved 11 April 2018.
  31. ^ Enard, W.; Przeworski, M.; Fisher, S. E.; Lai, C. S. L.; Wiebe, V.; Kitano, T.; Monaco, A. P.; Pääbo, S. (2002). "Molecular evolution of FOXP2, a gene involved in speech and language". Nature. 418 (6900): 869–872. Bibcode:2002Natur.418..869E. doi:10.1038/nature01025. hdl:11858/00-001M-0000-0012-CB89-A. PMID 12192408. S2CID 4416233.
  32. ^ Venter, J. C. (2007). "Time 100 scientists & thinkers. Svante Paabo". Time. Vol. 169, no. 20. p. 116. PMID 17536326.
  33. ^ Callaway, Ewen (12 February 2009) First draft of Neanderthal genome is unveiled 3 October 2022 at the Wayback Machine New Scientist, Life. Retrieved 13 February 2015
  34. ^ "Neanderthal genome completed". Max-Planck-Gesellschaft (Press release). 12 February 2009. from the original on 27 November 2021. Retrieved 4 October 2022.
  35. ^ Krause, J.; Fu, Q.; Good, J. M.; Viola, B.; Shunkov, M. V.; Derevianko, A. P.; Pääbo, S. (2010). "The complete mitochondrial DNA genome of an unknown hominin from southern Siberia". Nature. 464 (7290): 894–897. Bibcode:2010Natur.464..894K. doi:10.1038/nature08976. PMID 20336068.
  36. ^ Karlsson, Mattis (18 February 2022). From Fossil To Fact : The Denisova Discovery as Science in Action. Linköping Studies in Arts and Sciences. Vol. 830. Linköping: Linköping University Electronic Press. doi:10.3384/9789179291716. ISBN 978-91-7929-170-9. S2CID 246373889. from the original on 10 October 2022. Retrieved 9 October 2022.
  37. ^ Pääbo, Svante (2014). Neanderthal man : in search of lost genomes. New York. ISBN 978-0-465-02083-6. OCLC 862400377.
  38. ^ "Entire genome of extinct human decoded from fossil". www.mpg.de. Retrieved 15 December 2022.
  39. ^ "Viviane Slon among Nature's annual Top Ten". www.mpg.de. Retrieved 15 December 2022.
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  43. ^ Wong, Kate. "Neandertal Genome Study Reveals That We Have a Little Caveman in Us". Scientific American. "By way of explanation, the investigators suggest that the interbreeding occurred in the Middle East between 45,000 and 80,000 years ago, before moderns fanned out to other parts of the Old World and split into different groups."
  44. ^ Simon Underdown (3 April 2014) Neanderthal Man: In Search of Lost Genomes, by Svante Pääbo 14 July 2014 at the Wayback Machine Times Higher Education. Retrieved 1 July 2014
  45. ^ a b The ancient Neanderthal in severe COVID-19 4 May 2021 at the Wayback Machine, Science News, 30 September 2020. Retrieved 13 December 2020.
  46. ^ "Scopus preview – Pääbo, Svante – Author details – Scopus". scopus.com. from the original on 3 October 2022. Retrieved 16 October 2021.
  47. ^ "Member Directory: Svante Pääbo". Retrieved 3 December 2022.{{cite web}}: CS1 maint: url-status (link)
  48. ^ "Golden Plate Awardees of the American Academy of Achievement". achievement.org. American Academy of Achievement. from the original on 15 December 2016. Retrieved 13 July 2020.
  49. ^ . Archived from the original on 26 July 2011. Retrieved 27 July 2011.
  50. ^ . Archived from the original on 26 July 2011. Retrieved 27 July 2011.
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  56. ^ Powledge, Tabitha M. (6 March 2014). "Sexy Science: Neanderthals, Svante Pääbo and the story of how sex shaped modern humans". Genetic Literary Project. from the original on 22 November 2021. Retrieved 3 August 2019.

External links

 
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January 26, 2023
svante, pääbo, formemrs, swedish, ˈsvânːtɛ, ˈpʰɛ, ːbʊ, born, april, 1955, swedish, geneticist, nobel, laureate, specialises, field, evolutionary, genetics, founders, paleogenetics, worked, extensively, neanderthal, genome, 1997, became, founding, director, dep. Svante Paabo ForMemRS Swedish ˈsvanːtɛ ˈpʰɛ ːbʊ 3 born 20 April 1955 is a Swedish geneticist and Nobel Laureate who specialises in the field of evolutionary genetics 4 As one of the founders of paleogenetics he has worked extensively on the Neanderthal genome 5 6 In 1997 he became founding director of the Department of Genetics at the Max Planck Institute for Evolutionary Anthropology in Leipzig Germany 7 8 9 Since 1999 he has been an honorary professor at Leipzig University he currently teaches molecular evolutionary biology at the university 10 11 He is also an adjunct professor at Okinawa Institute of Science and Technology Japan 12 Svante PaaboForMemRSPaabo in 2016Born 1955 04 20 20 April 1955 age 67 Stockholm SwedenEducationUppsala University PhD Known forPaleogeneticsSpouseLinda Vigilant m 2008 wbr Children2RelativesSune Bergstrom father AwardsGottfried Wilhelm Leibniz Prize 1992 Max Delbruck Medal 1998 Louis Jeantet Prize for Medicine 2005 1 Pour le Merite 2008 Kistler Prize 2009 Great Cross of Merit with star 2009 Gruber Prize in Genetics 2013 Lomonosov Gold Medal 2014 Foreign Member of the Royal Society 2016 2 Breakthrough Prize in Life Sciences 2016 Keio Medical Science Prize 2016 Princess of Asturias Award 2018 Darwin Wallace Medal 2019 Japan Prize 2020 Massry Prize 2021 Nobel Prize in Physiology or Medicine 2022 Scientific careerFieldsGenetics Evolutionary anthropologyInstitutionsMax Planck Institute for Evolutionary Anthropology Leipzig University of Leipzig Okinawa Institute of Science and Technology University of Munich University of California Berkeley University of ZurichThesisHow the E19 Protein of Adenoviruses Modulates the Immune System 1986 In 2022 he was awarded the Nobel Prize in Physiology or Medicine for his discoveries concerning the genomes of extinct hominins and human evolution 13 14 15 Contents 1 Education and early life 2 Research and career 2 1 Awards and honours 3 Personal life 4 See also 5 References 6 External linksEducation and early life EditPaabo was born in Stockholm Sweden in 1955 and grew up there with his mother 5 Estonian chemist Karin Paabo Estonian ˈpaeːbo 1925 2013 who had escaped from the Soviet invasion in 1944 16 and arrived in Sweden as a refugee during World War II 17 18 He was born through a secret extramarital affair 19 of his father Swedish biochemist Sune Bergstrom 1916 2004 5 who like his son became a recipient of the Nobel Prize in Physiology or Medicine in 1982 20 Paabo is his mother s only child he has via his father s marriage a half brother also born in 1955 21 Paabo grew up as a native Swedish speaker 22 In a 2012 interview with the Estonian newspaper Eesti Paevaleht he said that he self identifies as a Swede but has a special relationship with Estonia 23 In 1975 Paabo began studying at Uppsala University serving one year in the Swedish Defense Forces attached to the School of Interpreters Paabo earned his Ph D from Uppsala University in 1986 for research investigating how the E19 protein of adenoviruses modulates the immune system 24 Research and career Edit Paabo at the 2014 Nobel Conference Paabo is known as one of the founders of paleogenetics a discipline that uses genetics to study early humans and other ancient species 25 26 From 1986 to 1987 he did postdoctoral research at the Institute for Molecular Biology II University of Zurich Switzerland 27 As an EMBO Postdoctoral Fellow Paabo moved to the United States in 1987 accepting a position as a postdoctoral researcher in biochemistry at the University of California Berkeley where he joined Allan Wilson s lab and worked on the genome of extinct mammals 27 28 In 1990 he returned to Europe to become professor of general biology at the University of Munich and in 1997 he became founding director of the Max Planck Institute for Evolutionary Anthropology in Leipzig Germany 28 In 1997 Paabo and colleagues reported their successful sequencing of Neanderthal mitochondrial DNA mtDNA originating from a specimen found in Feldhofer grotto in the Neander valley 29 30 In August 2002 Paabo s department published findings about the language gene FOXP2 which is mutated in some individuals with language disabilities 31 In 2006 Paabo announced a plan to reconstruct the entire genome of Neanderthals In 2007 he was named one of Time magazine s 100 most influential people of the year 32 In February 2009 at the Annual Meeting of the American Association for the Advancement of Science AAAS in Chicago it was announced that the Max Planck Institute for Evolutionary Anthropology had completed the first draft version of the Neanderthal genome 33 Over 3 billion base pairs were sequenced in collaboration with the 454 Life Sciences Corporation 34 In March 2010 Paabo and his coworkers published a report about the DNA analysis of a finger bone found in the Denisova Cave in Siberia the results suggest that the bone belonged to an extinct member of the genus Homo that had not yet been recognised the Denisova hominin 35 Paabo first wanted to classify the Denisovans as a species of their own separate from modern humans and Neanderthals but changed his mind after peer review 36 37 Paabo s doctoral student Viviane Slon was able to successfully map the Denisovan genome clarifying geographic distribution and admixtures in archaic humans 38 39 In May 2010 Paabo and his colleagues published a draft sequence of the Neanderthal genome in the journal Science 40 He and his team also concluded that there was probably interbreeding between Neanderthals and Eurasian but not Sub Saharan African humans 41 There is general mainstream support in the scientific community for this theory of interbreeding between archaic and modern humans 42 This admixture of modern human and Neanderthal genes is estimated to have occurred roughly between 50 000 and 60 000 years ago in the Middle East 43 In 2014 he published the book Neanderthal Man In Search of Lost Genomes where he in the mixed form of a memoir and popular science tells the story of the research effort to map the Neanderthal genome combined with his thoughts on human evolution 20 44 In 2020 Paabo determined that more severe impacts upon victims of the COVID 19 disease including the vulnerability to it and the incidence of the necessity of hospitalisation have been associated via DNA analysis to be expressed in genetic variants at chromosomal region 3 features that are associated with European Neanderthal heritage That structure imposes greater risks that those affected will develop a more severe form of the disease 45 The findings are from Paabo and researchers he leads at the Planck Institute and the Karolinska Institutet 45 As of October 2022 update Paabo has an h index of 167 according to Google Scholar 4 and of 133 according to Scopus 46 Awards and honours Edit In 1992 he received the Gottfried Wilhelm Leibniz Prize of the Deutsche Forschungsgemeinschaft which is the highest honour awarded in German research Paabo was elected a member of the Royal Swedish Academy of Sciences in 2000 and in 2004 was elected an international member of the National Academy of Sciences 47 In 2005 he received the prestigious Louis Jeantet Prize for Medicine 1 In 2008 Paabo was added to the members of the Order Pour le Merite for Sciences and Arts In the same year he received the Golden Plate Award of the American Academy of Achievement 48 In October 2009 the Foundation For the Future announced that Paabo had been awarded the 2009 Kistler Prize for his work isolating and sequencing ancient DNA beginning in 1984 with a 2 400 year old mummy 49 In June 2010 the Federation of European Biochemical Societies FEBS awarded him the Theodor Bucher Medal for outstanding achievements in Biochemistry and Molecular Biology 50 In 2013 he received Gruber Prize in Genetics for groundbreaking research in evolutionary genetics 51 In June 2015 he was awarded the degree of DSc honoris causa at NUI Galway 52 He was elected a Foreign Member of the Royal Society in 2016 2 and in 2017 was awarded the Dan David Prize In 2018 he received the Princess of Asturias Awards in the category of Scientific Research in 2020 the Japan Prize 53 in 2021 the Massry Prize 54 and in 2022 the Nobel Prize in Physiology or Medicine 55 for sequencing the first Neanderthal genome 14 Personal life EditPaabo wrote in his 2014 book Neanderthal Man In Search of Lost Genomes that he is bisexual He assumed he was gay until he met Linda Vigilant an American primatologist and geneticist whose boyish charms attracted him They have co authored many papers are married and raising a son and a daughter together in Leipzig 56 6 See also EditOrigins of Us 2011 BBC series First Peoples 2015 PBS series List of Nobel laureates in Physiology or Medicine List of Swedish Nobel laureatesReferences Edit a b Professor Svante PAABO Jeantet 1 October 2017 Archived from the original on 16 May 2021 Retrieved 16 October 2021 a b Svante Paabo London Royal Society 2016 Archived from the original on 29 April 2016 One or more of the preceding sentences incorporates text from the royalsociety org website where All text published under the heading Biography on Fellow profile pages is available under Creative Commons Attribution 4 0 International License Royal Society Terms conditions and policies Archived from the original on 25 September 2015 Retrieved 9 March 2016 Lena Nordlund Annlouise Martin Producers 14 August 2014 Svante Paabo MP3 Radio Sveriges Radio Event occurs at 1 15 Archived from the original on 3 October 2022 Retrieved 2 May 2018 a b Svante Paabo publications indexed by Google Scholar a b c Kolbert Elizabeth Sleeping with the Enemy What happened between the Neanderthals and us The New Yorker No 15 amp 22 August 2011 pp 64 75 Archived from the original on 11 July 2022 Retrieved 23 November 2021 a b Paabo Svante 2014 Neanderthal Man In Search of Lost Genomes Basic Books ISBN 978 0 465 02083 6 Gitschier J 2008 Imagine An Interview with Svante Paabo PLOS Genetics PLOS 4 3 e1000035 doi 10 1371 journal pgen 1000035 PMC 2274957 PMID 18369454 Zagorski N 2006 Profile of Svante Paabo Proceedings of the National Academy of Sciences of the United States of America 103 37 13575 13577 Bibcode 2006PNAS 10313575Z doi 10 1073 pnas 0606596103 PMC 1564240 PMID 16954182 Svante Paabo at the Max Planck Institute for Evolutionary Anthropology Archived from the original on 19 July 2011 Retrieved 27 July 2011 Heckmann Carsten Honorary professor at Leipzig University recognised Japan Prize Goes to Svante Paabo Leipzig University eipzig University Retrieved 17 October 2022 Heckmann Carsten Congratulations to our honorary professor Nobel Prize for Savante Paabo Leipzig University eipzig University Retrieved 17 October 2022 Svante Paabo OIST Groups 29 April 2020 Archived from the original on 24 October 2021 Retrieved 3 October 2022 Press release The Nobel Prize in Physiology or Medicine 2022 Archived from the original on 3 October 2022 Retrieved 3 October 2022 a b Grover Natalie Pollard Niklas Ahlander Johan 3 October 2022 Swedish geneticist wins Nobel medicine prize for decoding ancient DNA Reuters Archived from the original on 3 October 2022 Retrieved 3 October 2022 Nobel laureate Svante Paabo s ancient DNA discoveries shed light on what makes us human Onmanorama 6 October 2022 Archived from the original on 6 October 2022 Retrieved 6 October 2022 Kulli Riin Tigasson 17 March 2012 Svante Paabo mis tegi inimesest inimese Interview with subject Eesti Paevaleht in Estonian Retrieved 20 October 2022 Tambur Silver 3 October 2022 Estonian descendant Svante Paabo awarded Nobel prize EstonianWorld Archived from the original on 8 October 2022 Retrieved 8 October 2022 Strandberg Marek 4 October 2022 Eesti juurtega Svante Paabo toi kargperre teisegi Nobeli auhinna Postimees in Estonian subscription required Schultz Isaac 3 October 2022 Paleogeneticist Svante Paabo Picks Up Nobel Prize for Human Origins Research Gizmodo Archived from the original on 6 October 2022 Retrieved 6 October 2022 a b Peter Forbes 20 February 2014 Neanderthal Man In Search of Lost Genomes by Svante Paabo review Archived 1 December 2021 at the Wayback Machine Svensken Svante Paabo far Nobelpriset i medicin Dagens Nyheter in Swedish 3 October 2022 Archived from the original on 3 October 2022 Retrieved 3 October 2022 Kulli Riin Tigasson 17 March 2012 Svante Paabo mis tegi inimesest inimese Interview with subject Eesti Paevaleht in Estonian Retrieved 20 October 2022 Kulli Riin Tigasson 17 March 2012 Svante Paabo mis tegi inimesest inimese Interview with subject Eesti Paevaleht in Estonian Retrieved 20 October 2022 Paabo was quoted saying I grew up understanding what Estonia is but I don t speak Estonian I have never attended Estonian school I identify with the Swedes but I have a special relationship with Estonia Kasvasin ules teades mis on Eesti aga eesti keelt ma ei raagi Ma pole kunagi kainud eesti koolis Identifitseerin end rootslastega aga mul on eriline suhe Eestiga Paabo Svante 1986 How the E19 protein of adenoviruses modulates the immune system PhD thesis Uppsala University ISBN 9155419216 OCLC 16668494 Archived from the original on 3 October 2022 Retrieved 22 December 2016 Svante Paabo publications in PubMed Archived from the original on 3 October 2022 Retrieved 27 July 2011 Edge Mapping the Neanderthal Genome A Conversation With Svante Paabo Archived from the original on 13 December 2012 Retrieved 27 July 2011 a b Svante Paabo Max Planch Institute 3 October 2022 Archived from the original on 6 October 2022 Retrieved 6 October 2022 a b Daniela Mocker 4 October 2022 Nobel Winner Svante Paabo Discovered the Neandertal in Our Genes Scientific American Krings M Stone A Schmitz Rw Krainitzki H Stoneking M Paabo S 1997 Neandertal DNA sequences and the origin of modern humans Cell 90 1 19 30 doi 10 1016 S0092 8674 00 80310 4 hdl 11858 00 001M 0000 0025 0960 8 ISSN 0092 8674 PMID 9230299 S2CID 13581775 Rincon Paul 11 April 2018 How ancient DNA is transforming our view of the past BBC Archived from the original on 30 March 2019 Retrieved 11 April 2018 Enard W Przeworski M Fisher S E Lai C S L Wiebe V Kitano T Monaco A P Paabo S 2002 Molecular evolution of FOXP2 a gene involved in speech and language Nature 418 6900 869 872 Bibcode 2002Natur 418 869E doi 10 1038 nature01025 hdl 11858 00 001M 0000 0012 CB89 A PMID 12192408 S2CID 4416233 Venter J C 2007 Time 100 scientists amp thinkers Svante Paabo Time Vol 169 no 20 p 116 PMID 17536326 Callaway Ewen 12 February 2009 First draft of Neanderthal genome is unveiled Archived 3 October 2022 at the Wayback Machine New Scientist Life Retrieved 13 February 2015 Neanderthal genome completed Max Planck Gesellschaft Press release 12 February 2009 Archived from the original on 27 November 2021 Retrieved 4 October 2022 Krause J Fu Q Good J M Viola B Shunkov M V Derevianko A P Paabo S 2010 The complete mitochondrial DNA genome of an unknown hominin from southern Siberia Nature 464 7290 894 897 Bibcode 2010Natur 464 894K doi 10 1038 nature08976 PMID 20336068 Karlsson Mattis 18 February 2022 From Fossil To Fact The Denisova Discovery as Science in Action Linkoping Studies in Arts and Sciences Vol 830 Linkoping Linkoping University Electronic Press doi 10 3384 9789179291716 ISBN 978 91 7929 170 9 S2CID 246373889 Archived from the original on 10 October 2022 Retrieved 9 October 2022 Paabo Svante 2014 Neanderthal man in search of lost genomes New York ISBN 978 0 465 02083 6 OCLC 862400377 Entire genome of extinct human decoded from fossil www mpg de Retrieved 15 December 2022 Viviane Slon among Nature s annual Top Ten www mpg de Retrieved 15 December 2022 Green R E Krause J Briggs A W Maricic T Stenzel U Kircher M Patterson N Li H Zhai W Fritz M H Y Hansen N F Durand E Y Malaspinas A S Jensen J D Marques Bonet T Alkan C Prufer K Meyer M Burbano H A Good J M Schultz R Aximu Petri A Butthof A Hober B Hoffner B Siegemund M Weihmann A Nusbaum C Lander E S Russ C et al 2010 A Draft Sequence of the Neandertal Genome Science 328 5979 710 722 Bibcode 2010Sci 328 710G doi 10 1126 science 1188021 PMC 5100745 PMID 20448178 Rincon Paul 2010 Neanderthal genes survive in us BBC Archived from the original on 14 August 2012 Retrieved 7 May 2010 Lalueza Fox C Gilbert MTP 2011 Paleogenomics of Archaic Hominins Current Biology 21 24 R1002 R1009 doi 10 1016 j cub 2011 11 021 PMID 22192823 S2CID 14371551 Wong Kate Neandertal Genome Study Reveals That We Have a Little Caveman in Us Scientific American By way of explanation the investigators suggest that the interbreeding occurred in the Middle East between 45 000 and 80 000 years ago before moderns fanned out to other parts of the Old World and split into different groups Simon Underdown 3 April 2014 Neanderthal Man In Search of Lost Genomes by Svante Paabo Archived 14 July 2014 at the Wayback Machine Times Higher Education Retrieved 1 July 2014 a b The ancient Neanderthal in severe COVID 19 Archived 4 May 2021 at the Wayback Machine Science News 30 September 2020 Retrieved 13 December 2020 Scopus preview Paabo Svante Author details Scopus scopus com Archived from the original on 3 October 2022 Retrieved 16 October 2021 Member Directory Svante Paabo Retrieved 3 December 2022 a href Template Cite web html title Template Cite web cite web a CS1 maint url status link Golden Plate Awardees of the American Academy of Achievement achievement org American Academy of Achievement Archived from the original on 15 December 2016 Retrieved 13 July 2020 Foundation For the Future has selected Dr Svante Paabo as the 2009 winner of the Kistler Prize Archived from the original on 26 July 2011 Retrieved 27 July 2011 FEBS MEDALS The Theodor Bucher Lecture and Medal Archived from the original on 26 July 2011 Retrieved 27 July 2011 Gruber Genetics Prize for Svante Paabo MAX PLANCK GESELLSCHAFT Archived from the original on 17 March 2013 Retrieved 6 April 2013 ONE OF WORLD S MOST INFLUENTIAL SCIENTISTS TO SPEAK AT NUI GALWAY Archived from the original on 16 June 2015 Retrieved 13 June 2015 The Japan Prize Foundation japanprize jp Archived from the original on 4 February 2021 Retrieved 16 October 2021 Current Laureates Archived from the original on 1 December 2021 Retrieved 1 December 2021 The Nobel Prize in Physiology or Medicine 2022 Nobel Foundation Archived from the original on 3 October 2022 Retrieved 3 October 2022 Powledge Tabitha M 6 March 2014 Sexy Science Neanderthals Svante Paabo and the story of how sex shaped modern humans Genetic Literary Project Archived from the original on 22 November 2021 Retrieved 3 August 2019 External links Edit Wikimedia Commons has media related to Svante Paabo Scholia has an author profile for Svante Paabo Svante Paabo at the Max Planck Society Human Evolutionary Genomics Unit Svante Paabo Okinawa Institute of Science and Technology Graduate University Svante Paabo publications indexed by Google Scholar Svante Paabo on Nobelprize org Retrieved from https en 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