fbpx
Wikipedia

Sulfadimidine

Sulfadimidine or sulfamethazine is a sulfonamide antibacterial.

Sulfamethazine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 4-amino-N-(4,6-dimethylpyrimidin-2-yl)
    benzene-1-sulfonamide
CAS Number
  • 57-68-1 Y
PubChem CID
  • 5327
DrugBank
  • DB01582 Y
ChemSpider
  • 5136 Y
UNII
  • 48U51W007F
KEGG
  • D02436 Y
ChEBI
  • CHEBI:102265 Y
ChEMBL
  • ChEMBL446 Y
NIAID ChemDB
  • 027749
CompTox Dashboard (EPA)
  • DTXSID6021290
ECHA InfoCard100.000.315
Chemical and physical data
FormulaC12H14N4O2S
Molar mass278.33 g·mol−1
3D model (JSmol)
  • Interactive image
Melting point176 °C (349 °F)
  • O=S(=O)(Nc1nc(cc(n1)C)C)c2ccc(N)cc2
  • InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16) Y
  • Key:ASWVTGNCAZCNNR-UHFFFAOYSA-N Y
  (verify)

There are non-standardizeda abbreviations for it as "sulfadimidine" (abbreviated SDI[1][2] and more commonly but less reliablyb SDD[3][4]) and as "sulfamethazine" (abbreviated SMT[5][6] and more commonly but less reliablyc SMZ[7][8]). Other names include sulfadimerazine, sulfadimezine, and sulphadimethylpyrimidine.[citation needed]

References Edit

  1. ^ Romváry A, Simon F (1992). "Sulfonamide residues in eggs". Acta Veterinaria Hungarica. 40 (1–2): 99–106. PMID 1476095.
  2. ^ Reddy KS, Jain SK, Uppal RP (1988). "Pharmacokinetic studies of sulphonamides in poultry". Indian Journal of Animal Sciences.
  3. ^ Kamakura K, Hasegawa M, Koiguchi S, Miyata M, Okamoto K, Narita M, et al. (1993). "[Studies on the identification of sulfadimidine in pork by high performance liquid chromatography with photodiode array detector and gas chromatograph-mass spectrometry]". Eisei Shikenjo Hokoku. Bulletin of National Institute of Hygienic Sciences (111): 61–5. PMID 7920569.
  4. ^ Garg SK, Ghosh SS, Mathur VS (January 1986). "Comparative pharmacokinetic study of four different sulfonamides in combination with trimethoprim in human volunteers". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 24 (1): 23–5. PMID 3485584.
  5. ^ Peña MS, Salinas F, Mahedero MC, Aaron JJ (February 1994). "Solvent effect on the determination of sulfamethazine by room-temperature photochemically induced fluorescence". Talanta. 41 (2): 233–6. doi:10.1016/0039-9140(94)80113-4. PMID 18965913.
  6. ^ Kaniou S, Pitarakis K, Barlagianni I, Poulios I (July 2005). "Photocatalytic oxidation of sulfamethazine". Chemosphere. 60 (3): 372–80. doi:10.1016/j.chemosphere.2004.11.069. PMID 15924956.
  7. ^ Calvo R, Sarabia S, Carlos R, Du Souich P (Mar 1987). "Sulfamethazine absorption and disposition: effect of surgical procedures for gastroduodenal ulcers". Biopharmaceutics & Drug Disposition. 8 (2): 115–24. doi:10.1002/bdd.2510080203. PMID 3593892.
  8. ^ De Liguoro M, Fioretto B, Poltronieri C, Gallina G (June 2009). "The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim". Chemosphere. 75 (11): 1519–24. doi:10.1016/j.chemosphere.2009.02.002. PMID 19269673.

Further reading Edit

sulfadimidine, sulfamethazine, sulfonamide, antibacterial, sulfamethazineclinical, dataahfs, drugs, cominternational, drug, namesatc, codej01eb03, qj01eq03, qp51ag01, qp51ag51, identifiersiupac, name, amino, dimethylpyrimidin, benzene, sulfonamidecas, number57. Sulfadimidine or sulfamethazine is a sulfonamide antibacterial SulfamethazineClinical dataAHFS Drugs comInternational Drug NamesATC codeJ01EB03 WHO QJ01EQ03 WHO QP51AG01 WHO QP51AG51 WHO IdentifiersIUPAC name 4 amino N 4 6 dimethylpyrimidin 2 yl benzene 1 sulfonamideCAS Number57 68 1 YPubChem CID5327DrugBankDB01582 YChemSpider5136 YUNII48U51W007FKEGGD02436 YChEBICHEBI 102265 YChEMBLChEMBL446 YNIAID ChemDB027749CompTox Dashboard EPA DTXSID6021290ECHA InfoCard100 000 315Chemical and physical dataFormulaC 12H 14N 4O 2SMolar mass278 33 g mol 13D model JSmol Interactive imageMelting point176 C 349 F SMILES O S O Nc1nc cc n1 C C c2ccc N cc2InChI InChI 1S C12H14N4O2S c1 8 7 9 2 15 12 14 8 16 19 17 18 11 5 3 10 13 4 6 11 h3 7H 13H2 1 2H3 H 14 15 16 YKey ASWVTGNCAZCNNR UHFFFAOYSA N Y verify There are non standardizeda abbreviations for it as sulfadimidine abbreviated SDI 1 2 and more commonly but less reliablyb SDD 3 4 and as sulfamethazine abbreviated SMT 5 6 and more commonly but less reliablyc SMZ 7 8 Other names include sulfadimerazine sulfadimezine and sulphadimethylpyrimidine citation needed References Edit Romvary A Simon F 1992 Sulfonamide residues in eggs Acta Veterinaria Hungarica 40 1 2 99 106 PMID 1476095 Reddy KS Jain SK Uppal RP 1988 Pharmacokinetic studies of sulphonamides in poultry Indian Journal of Animal Sciences Kamakura K Hasegawa M Koiguchi S Miyata M Okamoto K Narita M et al 1993 Studies on the identification of sulfadimidine in pork by high performance liquid chromatography with photodiode array detector and gas chromatograph mass spectrometry Eisei Shikenjo Hokoku Bulletin of National Institute of Hygienic Sciences 111 61 5 PMID 7920569 Garg SK Ghosh SS Mathur VS January 1986 Comparative pharmacokinetic study of four different sulfonamides in combination with trimethoprim in human volunteers International Journal of Clinical Pharmacology Therapy and Toxicology 24 1 23 5 PMID 3485584 Pena MS Salinas F Mahedero MC Aaron JJ February 1994 Solvent effect on the determination of sulfamethazine by room temperature photochemically induced fluorescence Talanta 41 2 233 6 doi 10 1016 0039 9140 94 80113 4 PMID 18965913 Kaniou S Pitarakis K Barlagianni I Poulios I July 2005 Photocatalytic oxidation of sulfamethazine Chemosphere 60 3 372 80 doi 10 1016 j chemosphere 2004 11 069 PMID 15924956 Calvo R Sarabia S Carlos R Du Souich P Mar 1987 Sulfamethazine absorption and disposition effect of surgical procedures for gastroduodenal ulcers Biopharmaceutics amp Drug Disposition 8 2 115 24 doi 10 1002 bdd 2510080203 PMID 3593892 De Liguoro M Fioretto B Poltronieri C Gallina G June 2009 The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim Chemosphere 75 11 1519 24 doi 10 1016 j chemosphere 2009 02 002 PMID 19269673 Further reading EditChemDB Sulfamethazine ChemDB National Institute of Allergy and Infectious Diseases NIAID National Institutes of Health NIH Sulfadimidine in the ChemIDplus database PubChem Sulfamethazine Substance Summary PubChem National Center for Biotechnology Information NCBI National Library of Medicine NLM National Institutes of Health NIH nbsp This systemic antibiotic related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Sulfadimidine amp oldid 1179576581, wikipedia, wiki, book, books, library,

article

, read, download, free, free download, mp3, video, mp4, 3gp, jpg, jpeg, gif, png, picture, music, song, movie, book, game, games.