The outbreak was detected in children between 2006 and 2011, and in adults in the spring of 2011; the mortality rate in children was 58 percent, while among adults, 53 percent died or required lung transplants.[1]Autopsies and epidemiological work, followed up by animal studies, led the South Korean CDC to identify polyhexamethylene guanidine (PHMG) used in humidifier disinfectants as the cause.[1][2]
The main cause of the lung diseases was the chemicals PHMG, methylchloroisothiazolinone (CMIT), methylisothiazolinone (MIT) and oligo(2-(2-ethoxy)-ethoxyethyl)guanidinium-chloride (PGH).[3] Experiment of South Korean government found pulmonary toxicity of PHMG and PGH[4][5] PHMG and PGH caused pulmonary fibrosis when experimented on animals. On November 11, 2011, six humidifier disinfectants which contain PHMG and PGH were recovered. PHMG and PGH was banned in 2011, and new cases ceased occurring.[1][2]
However, later on, the Korea Centers for Disease Control and Prevention did not find a causal relationship that CMIT and MIT in humidifier disinfectants cause pulmonary fibrosis. This result, still, did not mean that CMIT and MIT were safe,[4] as the chemicals also affected the brain and skin to varying extents.[6] At least five victims used CMIT or MIT-based humidifier disinfectants.[7][8]
Most victims used Reckitt Benckiser's humidifier disinfectant, Oxy Ssak Ssak (옥시싹싹), which led the British firm to various court indictments in the years following 2011.[9][10][11]
^ abcCummings, K. J.; Kreiss, K. (2015). "Occupational and environmental bronchiolar disorders". Seminars in Respiratory and Critical Care Medicine. 36 (3): 366–78. doi:10.1055/s-0035-1549452. PMC4610354. PMID 26024345.
^ abDirk W. Lachenmeier (2015). "Chapter 24 – Antiseptic Drugs and Disinfectants". Side Effects of Drugs Annual. Vol. 37. pp. 273–279. doi:10.1016/bs.seda.2015.06.005. ISBN9780444635259.
^"'가습기살균제' 새 재판부 "사회적 참사라는 성찰 아래 공방해야"". The Dong-a Ilbo. November 12, 2019.
^ ab"알림 > 보도설명 내용보기 " [4월12일, 경향신문] 보건복지부는 ´독성 없다던 가습기살균제, 환경부선 작년 ´유독물´ 지정´, ´환경부 "가습기 살균 물질 극소량 노출된 흰쥐 절반이 죽어" 관련 보도 해명자료 " | 힘이 되는 평생 친구, 보건복지부". www.mohw.go.kr.
south, korean, humidifier, disinfectant, case, humidifier, disinfectant, case, outbreak, lung, diseases, south, korea, caused, chemicals, contained, humidifier, disinfectants, hangul가습기, 살균제, 사건hanja加濕器, 殺菌劑, 事件revised, romanizationgaseupgi, salgyunje, sageonm. The humidifier disinfectant case was an outbreak of lung diseases in South Korea caused by chemicals contained in humidifier disinfectants South Korean humidifier disinfectant caseHangul가습기 살균제 사건Hanja加濕器 殺菌劑 事件Revised RomanizationGaseupgi salgyunje sageonMcCune ReischauerKasŭpki salgyunje sagŏnThe outbreak was detected in children between 2006 and 2011 and in adults in the spring of 2011 the mortality rate in children was 58 percent while among adults 53 percent died or required lung transplants 1 Autopsies and epidemiological work followed up by animal studies led the South Korean CDC to identify polyhexamethylene guanidine PHMG used in humidifier disinfectants as the cause 1 2 The main cause of the lung diseases was the chemicals PHMG methylchloroisothiazolinone CMIT methylisothiazolinone MIT and oligo 2 2 ethoxy ethoxyethyl guanidinium chloride PGH 3 Experiment of South Korean government found pulmonary toxicity of PHMG and PGH 4 5 PHMG and PGH caused pulmonary fibrosis when experimented on animals On November 11 2011 six humidifier disinfectants which contain PHMG and PGH were recovered PHMG and PGH was banned in 2011 and new cases ceased occurring 1 2 However later on the Korea Centers for Disease Control and Prevention did not find a causal relationship that CMIT and MIT in humidifier disinfectants cause pulmonary fibrosis This result still did not mean that CMIT and MIT were safe 4 as the chemicals also affected the brain and skin to varying extents 6 At least five victims used CMIT or MIT based humidifier disinfectants 7 8 Most victims used Reckitt Benckiser s humidifier disinfectant Oxy Ssak Ssak 옥시싹싹 which led the British firm to various court indictments in the years following 2011 9 10 11 The South Korean film Air Murder is based on these events See also editReckitt BenckiserReferences edit a b c Cummings K J Kreiss K 2015 Occupational and environmental bronchiolar disorders Seminars in Respiratory and Critical Care Medicine 36 3 366 78 doi 10 1055 s 0035 1549452 PMC 4610354 PMID 26024345 a b Dirk W Lachenmeier 2015 Chapter 24 Antiseptic Drugs and Disinfectants Side Effects of Drugs Annual Vol 37 pp 273 279 doi 10 1016 bs seda 2015 06 005 ISBN 9780444635259 가습기살균제 새 재판부 사회적 참사라는 성찰 아래 공방해야 The Dong a Ilbo November 12 2019 a b 알림 gt 보도설명 내용보기 4월12일 경향신문 보건복지부는 독성 없다던 가습기살균제 환경부선 작년 유독물 지정 환경부 가습기 살균 물질 극소량 노출된 흰쥐 절반이 죽어 관련 보도 해명자료 힘이 되는 평생 친구 보건복지부 www mohw go kr 가습기살균제 폐손상 최종 확인 ktv go kr Korean Journal of Environmental Biology www ebr or kr doi 10 11626 KJEB 2020 38 2 271 S2CID 225755701 가습기살균제 위해 성분 2종 유독물 지정 KBS 뉴스 정부 괜찮다 던 가습기살균제에 18명 사망 40명 환자 고발뉴스닷컴 www gobalnews com 가습기 살균제 최대 피해낸 옥시싹싹 독성실험없이 출시 Yonhap News Agency April 27 2016 이 효상 December 26 2022 가습기 살균제 무죄 2심은 뒤집힐까 weekly khan co kr 가습기살균제 참사 항소심 게임 체인저 부상 왜 www ilyosisa co kr December 27 2022 Retrieved from https en wikipedia org w index php title South Korean humidifier disinfectant case amp oldid 1214614481, wikipedia, wiki, book, books, library,
