In 2005, Bodmer was appointed to lead a £2.3 million project (roughly US$4.5 million) by the Wellcome Trust at the University of Oxford to examine the genetic makeup of the United Kingdom – the People of the British Isles project. He was joined by Oxford Professor Peter Donnelly (a population genetics and statistics expert) and the Wellcome Trust Principal Research Fellow Lon Cardon. Bodmer said, "Our aim is to characterise the genetic make-up of the British population and relate this to the historical and archaeological evidence." The researchers presented some of their findings to the public via the Channel 4 television series "Faces of Britain". On 14 April 2007, Channel 4 in Britain aired a program that highlighted the study's then-current findings. The project took DNA samples from hundreds of volunteers throughout Britain, seeking tell-tale fragments of DNA that would reveal the biological traces of successive waves of colonisers – Celts, Saxons, Vikings, etc. – in various parts of Britain. The findings showed that the Viking invasion of Britain was predominantly from Danish Vikings while the Orkney Islands were settled by Norwegian Vikings. This research was most recently presented at the Galton Institute's conference on 'New Light on Old Britons' in 2019.[21] Bodmer had previously worked with the Galton Institute as its president from 2008 to 2014.[22]
He has been head of the cancer and immunogenetics laboratory in the Weatherall Institute of Molecular Medicine at the University of Oxford since 1996.[23] Research interests of the laboratory include the fundamental genetics and biology of colorectal cancer.
His certificate of election to the Royal Society reads:[25]
Distinguished for his theoretical and experimental contributions to genetics. His analyses of population genetics models, especially human, his contribution to the understanding of bacterial transformation, to the understanding of the HL-A system, and to the use of somatic cell hybrids for human linkage studies are outstanding. Few scientists have contributed distinguished work in such a range of fields, and involving such a range of experience of techniques, mathematical and experimental, and such a range of organisms.
Personal lifeedit
Bodmer's father was Jewish so the family were obliged to leave Nazi Germany; in 1938, they settled in Manchester, England. In 1956, Walter Bodmer married Julia Bodmer (née Pilkington) 1934–2001; she also became a well-known geneticist. They had two sons and a daughter.[6] Lady Bodmer died in 2001.
Interviewsedit
Bodmer, Walter; Blythe, Max (2017). "Sir Walter Bodmer FRS in interview with Dr Max Blythe: Interview 1". Oxford Brookes University. doi:10.24384/000458. {{cite journal}}: Cite journal requires |journal= (help)
Bodmer, Walter; Blythe, Max (1998). "Sir Walter Bodmer FRS in interview with Dr Max Blythe: Interview 2". Oxford Brookes University. doi:10.24384/000007. {{cite journal}}: Cite journal requires |journal= (help)
Referencesedit
^Cavalli-Sforza, L. L. (1981). "The William Allan Memorial Award: Presented to Walter F. Bodmer, PhD, at the annual meeting of the American Society of Human Genetics New York, September 24–27, 1980". American Journal of Human Genetics. 33 (5): 659–63. PMC1685126. PMID 7027789.
^Feldman, Marcus (1979). Some topics in theoretical population genetics (PhD thesis). Stanford University. OCLC 651748270.
^Goodfellow, Peter Neville (1975). Biochemical and Genetic Studies of Human Tissue Antigens (DPhil thesis). University of Oxford. OCLC 500453850. EThOS uk.bl.ethos.456975.
^van Heyningen, Veronica (1973). Mitochondrial and other Enzymes in Somatic Cell Hybrids. ora.ox.ac.uk (DPhil thesis). University of Oxford. OCLC 500471367.
^ abAnon (2015). "Bodmer, Sir Walter (Fred)". Who's Who (online Oxford University Press ed.). A & C Black. doi:10.1093/ww/9780199540884.013.U7957. (Subscription or UK public library membership required.)
^The Times 10 January 2009. Retrieved 9 January 2010 (subscription required)
^Leslie, S; Winney, B; Hellenthal, G; Davison, D; Boumertit, A; Day, T; Hutnik, K; Royrvik, E. C.; Cunliffe, B; Wellcome Trust Case Control Consortium 2; International Multiple Sclerosis Genetics Consortium; Lawson, D. J.; Falush, D; Freeman, C; Pirinen, M; Myers, S; Robinson, M; Donnelly, P; Bodmer, W (2015). "The fine-scale genetic structure of the British population". Nature. 519 (7543): 309–14. Bibcode:2015Natur.519..309.. doi:10.1038/nature14230. PMC4632200. PMID 25788095.{{cite journal}}: CS1 maint: numeric names: authors list (link)
^Rodrigues, N. R.; Rowan, A; Smith, M. E.; Kerr, I. B.; Bodmer, W. F.; Gannon, J. V.; Lane, D. P. (1990). "P53 mutations in colorectal cancer". Proceedings of the National Academy of Sciences of the United States of America. 87 (19): 7555–9. Bibcode:1990PNAS...87.7555R. doi:10.1073/pnas.87.19.7555. PMC54786. PMID 1699228.
^. University of Oxford. Archived from the original on 17 April 2015.
^. University of Oxford. Archived from the original on 4 March 2015.
^Hemminki, A.; Markie, D.; Tomlinson, I.; Avizienyte, E.; Roth, S.; Loukola, A.; Bignell, G.; Warren, W.; Aminoff, M.; Höglund, P.; Järvinen, H.; Kristo, P.; Pelin, K.; Ridanpää, M.; Salovaara, R.; Toro, T.; Bodmer, W.; Olschwang, S.; Olsen, A. S.; Stratton, M. R.; de la Chapelle, A.; Aaltonen, L. A. (1998). "A serine/threonine kinase gene defective in Peutz-Jeghers syndrome". Nature. 391 (6663): 184–7. Bibcode:1998Natur.391..184H. doi:10.1038/34432. PMID 9428765. S2CID 4400728.
^Bodmer, W; Bonilla, C (2008). "Common and rare variants in multifactorial susceptibility to common diseases". Nature Genetics. 40 (6): 695–701. doi:10.1038/ng.f.136. PMC2527050. PMID 18509313.
^Walter Bodmer's publications indexed by the Scopus bibliographic database. (subscription required)
^. British Society of Immunology. Archived from the original on 2 April 2015.
^. Stanford University. Archived from the original on 13 August 2014.
^Conversation with Walter Bodmer, San Francisco, 4 Dec.2010
^Sloman, Steven; Fernbach, Philip (2017). The Knowledge Illusion. London: Macmillan. p. 157. ISBN978-1-5098-1106-9.
^. Royal Society. Archived from the original on 19 October 2013.
walter, bodmer, walter, fred, bodmer, frse, born, january, 1936, german, born, british, human, geneticist, sirfrs, frsebornwalter, fred, bodmer, 1936, january, 1936, frankfurt, nazi, germanyeducationmanchester, grammar, schoolalma, materuniversity, cambridge, . Sir Walter Fred Bodmer FRS FRSE born 10 January 1936 7 is a German born British human geneticist 8 9 10 11 12 13 14 SirWalter BodmerFRS FRSEBornWalter Fred Bodmer 1936 01 10 10 January 1936 age 88 6 Frankfurt Nazi GermanyEducationManchester Grammar SchoolAlma materUniversity of Cambridge BA PhD SpouseJulia Bodmer m 1956 died 2001 wbr AwardsRoyal Medal 2013 Dalton Medal 2002 Michael Faraday Prize 1994 Ellison Cliffe Lecture 1987 Knight Bachelor 1986 Mendel Medal 1981 William Allan Award 1980 1 Scientific careerInstitutionsStanford University University of OxfordThesisThe study of population genetics and gene effects with special reference to Primula vulgaris and the house mouse 1959 Academic advisorsRonald Fisher 2 Doctoral studentsMarcus Feldman 2 3 Peter Goodfellow 4 Veronica van Heyningen 5 Websiteimm wbr ox wbr ac wbr uk wbr walter bodmer 2 www wbr oncology wbr ox wbr ac wbr uk wbr research wbr walter bodmer Walter Bodmer presenting at the ICG 18 conference in Nanjing China Contents 1 Early life 2 Career and research 2 1 Honours and awards 3 Personal life 4 Interviews 5 References 6 External linksEarly life editBodmer was born in Frankfurt Germany 15 He was educated at Manchester Grammar School and went on to study the Mathematical Tripos at the University of Cambridge as a student of Clare College Cambridge He was awarded his PhD in 1959 from Cambridge for research on population genetics in the house mouse and Primula vulgaris primrose supervised by Ronald Fisher 2 Career and research editIn 1961 Bodmer joined Joshua Lederberg s laboratory in the genetics department of Stanford University as a postdoctoral researcher continuing his work on population genetics 16 In 1962 Walter Bodmer was appointed to the faculty at Stanford He left Stanford University in 1970 to become the first professor of genetics at the University of Oxford 1 17 Bodmer developed models for population genetics and worked on the human leukocyte antigen system and the use of somatic cell hybrids for human linkage studies In 1985 he chaired a Royal Society committee which wrote The Bodmer Report this has been credited 18 with starting the movement for the public understanding of science 19 Bodmer was one of the first to suggest the idea of the Human Genome Project 20 In 1987 he received the Ellison Cliffe Medal from the Royal Society of Medicine He was the director of research 1979 1991 and then director general 1991 1996 of the Imperial Cancer Research Fund He was also chancellor of the University of Salford England 1995 2005 succeeded by Sir Martin Harris and principal of Hertford College Oxford 1996 2005 succeeded by Dr John Landers In 2005 Bodmer was appointed to lead a 2 3 million project roughly US 4 5 million by the Wellcome Trust at the University of Oxford to examine the genetic makeup of the United Kingdom the People of the British Isles project He was joined by Oxford Professor Peter Donnelly a population genetics and statistics expert and the Wellcome Trust Principal Research Fellow Lon Cardon Bodmer said Our aim is to characterise the genetic make up of the British population and relate this to the historical and archaeological evidence The researchers presented some of their findings to the public via the Channel 4 television series Faces of Britain On 14 April 2007 Channel 4 in Britain aired a program that highlighted the study s then current findings The project took DNA samples from hundreds of volunteers throughout Britain seeking tell tale fragments of DNA that would reveal the biological traces of successive waves of colonisers Celts Saxons Vikings etc in various parts of Britain The findings showed that the Viking invasion of Britain was predominantly from Danish Vikings while the Orkney Islands were settled by Norwegian Vikings This research was most recently presented at the Galton Institute s conference on New Light on Old Britons in 2019 21 Bodmer had previously worked with the Galton Institute as its president from 2008 to 2014 22 He has been head of the cancer and immunogenetics laboratory in the Weatherall Institute of Molecular Medicine at the University of Oxford since 1996 23 Research interests of the laboratory include the fundamental genetics and biology of colorectal cancer Honours and awards edit Bodmer has won numerous awards including 1972 Elected member of the American Academy of Arts and Sciences 24 1974 Fellow of the Royal Society 25 26 1980 William Allan Award 1981 Elected member of the United States National Academy of Sciences 27 1986 Knight Bachelor 1987 Ellison Cliffe Medal from the Royal Society of Medicine 1988 Honorary Degree Doctor of Science from the University of Bath 28 1989 Elected member of the American Philosophical Society 27 1992 Honorary Fellow of the Royal Society of Edinburgh FRSE 1994 Michael Faraday Prize 2013 Royal Medal from the Royal Society 1984 delivered the Royal Institution Christmas Lectures on The Message of the Genes Honorary member British Society for Immunology 29 His certificate of election to the Royal Society reads 25 Distinguished for his theoretical and experimental contributions to genetics His analyses of population genetics models especially human his contribution to the understanding of bacterial transformation to the understanding of the HL A system and to the use of somatic cell hybrids for human linkage studies are outstanding Few scientists have contributed distinguished work in such a range of fields and involving such a range of experience of techniques mathematical and experimental and such a range of organisms Personal life editBodmer s father was Jewish so the family were obliged to leave Nazi Germany in 1938 they settled in Manchester England In 1956 Walter Bodmer married Julia Bodmer nee Pilkington 1934 2001 she also became a well known geneticist They had two sons and a daughter 6 Lady Bodmer died in 2001 Interviews editBodmer Walter Blythe Max 2017 Sir Walter Bodmer FRS in interview with Dr Max Blythe Interview 1 Oxford Brookes University doi 10 24384 000458 a href Template Cite journal html title Template Cite journal cite journal a Cite journal requires journal help Bodmer Walter Blythe Max 1998 Sir Walter Bodmer FRS in interview with Dr Max Blythe Interview 2 Oxford Brookes University doi 10 24384 000007 a href Template Cite journal html title Template Cite journal cite journal a Cite journal requires journal help References edit Cavalli Sforza L L 1981 The William Allan Memorial Award Presented to Walter F Bodmer PhD at the annual meeting of the American Society of Human Genetics New York September 24 27 1980 American Journal of Human Genetics 33 5 659 63 PMC 1685126 PMID 7027789 a b c Walter Bodmer at the Mathematics Genealogy Project Feldman Marcus 1979 Some topics in theoretical population genetics PhD thesis Stanford University OCLC 651748270 Goodfellow Peter Neville 1975 Biochemical and Genetic Studies of Human Tissue Antigens DPhil thesis University of Oxford OCLC 500453850 EThOS uk bl ethos 456975 van Heyningen Veronica 1973 Mitochondrial and other Enzymes in Somatic Cell Hybrids ora ox ac uk DPhil thesis University of Oxford OCLC 500471367 nbsp a b Anon 2015 Bodmer Sir Walter Fred Who s Who online Oxford University Press ed A amp C Black doi 10 1093 ww 9780199540884 013 U7957 Subscription or UK public library membership required The Times 10 January 2009 Retrieved 9 January 2010 subscription required Leslie S Winney B Hellenthal G Davison D Boumertit A Day T Hutnik K Royrvik E C Cunliffe B Wellcome Trust Case Control Consortium 2 International Multiple Sclerosis Genetics Consortium Lawson D J Falush D Freeman C Pirinen M Myers S Robinson M Donnelly P Bodmer W 2015 The fine scale genetic structure of the British population Nature 519 7543 309 14 Bibcode 2015Natur 519 309 doi 10 1038 nature14230 PMC 4632200 PMID 25788095 a href Template Cite journal html title Template Cite journal cite journal a CS1 maint numeric names authors list link Rodrigues N R Rowan A Smith M E Kerr I B Bodmer W F Gannon J V Lane D P 1990 P53 mutations in colorectal cancer Proceedings of the National Academy of Sciences of the United States of America 87 19 7555 9 Bibcode 1990PNAS 87 7555R doi 10 1073 pnas 87 19 7555 PMC 54786 PMID 1699228 Prof Sir Walter Bodmer FRS Weatherhall Institute for Molecular Medicine University of Oxford Archived from the original on 17 April 2015 Walter Bodmer Cancer and Immunogenetics Laboratory University of Oxford Archived from the original on 4 March 2015 Hemminki A Markie D Tomlinson I Avizienyte E Roth S Loukola A Bignell G Warren W Aminoff M Hoglund P Jarvinen H Kristo P Pelin K Ridanpaa M Salovaara R Toro T Bodmer W Olschwang S Olsen A S Stratton M R de la Chapelle A Aaltonen L A 1998 A serine threonine kinase gene defective in Peutz Jeghers syndrome Nature 391 6663 184 7 Bibcode 1998Natur 391 184H doi 10 1038 34432 PMID 9428765 S2CID 4400728 Bodmer W Bonilla C 2008 Common and rare variants in multifactorial susceptibility to common diseases Nature Genetics 40 6 695 701 doi 10 1038 ng f 136 PMC 2527050 PMID 18509313 Walter Bodmer s publications indexed by the Scopus bibliographic database subscription required BSI HONORARY MEMBER Sir Walter Bodmer British Society of Immunology Archived from the original on 2 April 2015 Early Computers at Stanford Stanford University Archived from the original on 13 August 2014 Conversation with Walter Bodmer San Francisco 4 Dec 2010 Sloman Steven Fernbach Philip 2017 The Knowledge Illusion London Macmillan p 157 ISBN 978 1 5098 1106 9 Public Understanding of Science 1985 Royal Society Archived from the original on 19 October 2013 HUGO presidents Archived from the original on 8 April 2015 Past Events The Galton Institute Retrieved 18 November 2020 Past Presidents The Galton Institute Retrieved 18 November 2020 Walter Bodmer Retrieved 2 December 2020 Walter Fred Bodmer 13 October 2023 a b EC 1974 01 Bodmer Walter Fred London The Royal Society Archived from the original on 15 October 2015 Sir Walter Bodmer FMedSci FRS London Royal Society Archived from the original on 9 October 2015 a b Walter Bodmer Honorary Graduates 1989 to present bath ac uk University of Bath Retrieved 18 February 2012 British Society for Immunology External links editChannel 4s Faces of Britain Walter Bodmer on the History of Modern Biomedicine Research Group website Colorectal cancer research at the IMM Catalogue of the archive of Sir Walter Bodmer and Lady Julia Bodmer held at the Bodleian Library University of Oxford Portraits of Statisticians Walter Bodmer Radio National Australia interview with Sir Walter Portraits of Sir Walter Fred Bodmer at the National Portrait Gallery London Academic offices Preceded byThe Duchess of York Chancellor of the University of Salford1995 2006 Succeeded bySir Martin Harris Preceded byChristopher Zeeman Principal of Hertford College Oxford1996 2005 Succeeded byJohn Landers Portals nbsp United Kingdom nbsp Biography nbsp Science 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