Roussin's red salt anion is an edge-shared bitetrahedron, wherein a pair Fe(NO)2 units are bridged by a pair of sulfide ligands. The Fe-NO bonds are linear indicating NO is acting as a three electron donor.[3] The diamagnetic compound obeys the 18-electron rule. The dark red colour of the complex is attributed to a number of charge-transfer interactions between the iron core and nitrosyl ligands.[4]
Synthesis
The French chemist Z. Roussin[5] first prepared this salt while investigating reactions between nitroprusside ion ([Fe(CN)5NO]2−) and sulfur.[6] The salt can be prepared by the reaction of sulfide salts with iron nitrosyl halides:[7]
Fe2I2(NO)4 + 2Li2S → Li2Fe2S2(NO)4 + 2LiI
To obtain the "esters", the salt is alkylated:
Li2Fe2S2(NO)4 + 2 RX → Fe2(SR)2(NO)4 + 2 LiX
Esters can also be easily be prepared from the reaction of Fe2I2(NO)4 with the thiol.
Occurrence and potential applications
It is found in nature as its "esters" with the formula Fe2(SR)2(NO)4, where "R" is any alkyl group.[3] In addition Roussin's red salt is discussed in the fields of microbiology and food science due to its mutagenic properties.[8]
The ester derivative are being investigated as nitric oxide donors in biology and medicine, due to the relatively low toxicity and good stability of Roussin's red salt.[9]Photodissociation of the compound induces the release of NO, thereby sensitizing target cells to exposure to radiation.[8]
^Butler, Anthony R. (July 1982). "The chemist Z. Roussin (1827-94)". Journal of Chemical Education. 59 (7): 549. Bibcode:1982JChEd..59..549B. doi:10.1021/ed059p549.
^Roussin, M. L. (1858). "Recherches sur les nitrosulfures doubles de fer (nouvelle classe de sels)". Ann. Chim. Phys. 52: 285–303.
^ abThomas, J. T.; Robertson, J. H.; Cox, E. G. (1 September 1958). "The crystal structure of Roussin's red ethyl ester". Acta Crystallographica. 11 (9): 599–604. doi:10.1107/S0365110X58001602.
^Jaworska, Maria; Stasicka, Zofia (2005). "Structure and UV-Vis spectroscopy of the iron-sulfur dinuclear nitrosyl complexes [Fe2S2(NO)4]2− and [Fe2(SR)2(NO)4]". New Journal of Chemistry. 29 (4): 604. doi:10.1039/B409519G.
^Butler, Anthony R. (July 1982). "The chemist Z. Roussin (1827-94)". Journal of Chemical Education. 59 (7): 549. Bibcode:1982JChEd..59..549B. doi:10.1021/ed059p549.
^Hans Reihlen, Adolf v. Friedolsheim (1927). "Über komplexe Stickoxydverbindungen und das sogenannte einwertige Eisen". Justus Liebigs Annalen der Chemie. 457: 71–82. doi:10.1002/jlac.19274570103.
^TB Rauchfuss; TD Weatherill (1982). "Roussin's Red Salt revisited: reactivity of Fe2 (μ-E) 2 (NO) 42-(E= S, Se, Te) and related". Inorganic Chemistry. 21 (2): 827–830. doi:10.1021/ic00132a071.
^ abGreenwood, N. N.; & Earnshaw, A. (1997). Chemistry of the Elements (2nd Edn.), Oxford:Butterworth-Heinemann. ISBN0-7506-3365-4.
^Yoon, H.; Park, S.; Lim, M. (2020). "Photorelease Dynamics of Nitric Oxide from Cysteine-Bound Roussin's Red Ester". The Journal of Physical Chemistry Letters. 11 (9): 3198–3202. doi:10.1021/acs.jpclett.0c00739. PMID 32250631. S2CID 215408785.
January 29, 2023
roussin, salt, inorganic, compound, with, formula, fe2s2, this, metal, nitrosyl, first, described, zacharie, roussin, 1858, making, first, synthetic, iron, sulfur, clusters, namesiupac, name, potassium, tetranitrosyl, sulfidodiiron, other, names, ferrate, tetr. Roussin s red salt is the inorganic compound with the formula K2 Fe2S2 NO 4 This metal nitrosyl was first described by Zacharie Roussin in 1858 making it one of the first synthetic iron sulfur clusters 1 2 Roussin s red salt NamesIUPAC name potassium tetranitrosyl di m sulfidodiiron Fe Fe 2 Other names Ferrate 2 tetranitrosyldi mu thioxodi Fe Fe dipotassiumIdentifiersCAS Number 58204 17 43D model JSmol Interactive imageChemSpider 142967PubChem CID 162850CompTox Dashboard EPA DTXSID20973767InChI InChI 1S 2Fe 4NO 2S c 4 1 2 q 4 1 2 2Key HAJABACXLZMFIH UHFFFAOYSA NSMILES K O 23 N Fe 5 N 2B 23 O 2B 12S Fe 5 N 2B 23 O 2B N 2B 23 O 2B 1S2 K PropertiesChemical formula Fe2N4K2O4S2Molar mass 374 04 g molAppearance Dark red crystalsExcept where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Y verify what is Y N Infobox references Contents 1 Structure and bonding 2 Synthesis 3 Occurrence and potential applications 4 See also 5 ReferencesStructure and bonding EditRoussin s red salt anion is an edge shared bitetrahedron wherein a pair Fe NO 2 units are bridged by a pair of sulfide ligands The Fe NO bonds are linear indicating NO is acting as a three electron donor 3 The diamagnetic compound obeys the 18 electron rule The dark red colour of the complex is attributed to a number of charge transfer interactions between the iron core and nitrosyl ligands 4 Synthesis EditThe French chemist Z Roussin 5 first prepared this salt while investigating reactions between nitroprusside ion Fe CN 5NO 2 and sulfur 6 The salt can be prepared by the reaction of sulfide salts with iron nitrosyl halides 7 Fe2I2 NO 4 2Li2S Li2Fe2S2 NO 4 2LiITo obtain the esters the salt is alkylated Li2Fe2S2 NO 4 2 RX Fe2 SR 2 NO 4 2 LiXEsters can also be easily be prepared from the reaction of Fe2I2 NO 4 with the thiol Occurrence and potential applications EditIt is found in nature as its esters with the formula Fe2 SR 2 NO 4 where R is any alkyl group 3 In addition Roussin s red salt is discussed in the fields of microbiology and food science due to its mutagenic properties 8 The ester derivative are being investigated as nitric oxide donors in biology and medicine due to the relatively low toxicity and good stability of Roussin s red salt 9 Photodissociation of the compound induces the release of NO thereby sensitizing target cells to exposure to radiation 8 See also EditRoussin s black saltReferences Edit Butler Anthony R July 1982 The chemist Z Roussin 1827 94 Journal of Chemical Education 59 7 549 Bibcode 1982JChEd 59 549B doi 10 1021 ed059p549 Roussin M L 1858 Recherches sur les nitrosulfures doubles de fer nouvelle classe de sels Ann Chim Phys 52 285 303 a b Thomas J T Robertson J H Cox E G 1 September 1958 The crystal structure of Roussin s red ethyl ester Acta Crystallographica 11 9 599 604 doi 10 1107 S0365110X58001602 Jaworska Maria Stasicka Zofia 2005 Structure and UV Vis spectroscopy of the iron sulfur dinuclear nitrosyl complexes Fe2S2 NO 4 2 and Fe2 SR 2 NO 4 New Journal of Chemistry 29 4 604 doi 10 1039 B409519G Butler Anthony R July 1982 The chemist Z Roussin 1827 94 Journal of Chemical Education 59 7 549 Bibcode 1982JChEd 59 549B doi 10 1021 ed059p549 Hans Reihlen Adolf v Friedolsheim 1927 Uber komplexe Stickoxydverbindungen und das sogenannte einwertige Eisen Justus Liebigs Annalen der Chemie 457 71 82 doi 10 1002 jlac 19274570103 TB Rauchfuss TD Weatherill 1982 Roussin s Red Salt revisited reactivity of Fe2 m E 2 NO 42 E S Se Te and related Inorganic Chemistry 21 2 827 830 doi 10 1021 ic00132a071 a b Greenwood N N amp Earnshaw A 1997 Chemistry of the Elements 2nd Edn Oxford Butterworth Heinemann ISBN 0 7506 3365 4 Yoon H Park S Lim M 2020 Photorelease Dynamics of Nitric Oxide from Cysteine Bound Roussin s Red Ester The Journal of Physical Chemistry Letters 11 9 3198 3202 doi 10 1021 acs jpclett 0c00739 PMID 32250631 S2CID 215408785 Retrieved from https en wikipedia org w index php title Roussin 27s red salt amp oldid 1125906096, wikipedia, wiki, book, books, library,
