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Psychobiotic

Psychobiotics is a term used in preliminary research to refer to live bacteria that, when ingested in appropriate amounts, might confer a mental health benefit by affecting microbiota of the host organism.[1] Whether bacteria might play a role in the gut-brain axis is under research. A 2020 literature review suggests that the consumption of psychobiotics could be considered as a viable option to restore mental health[2] although lacking randomized controlled trials on clear mental health outcomes in humans.[3][4]

Types edit

 
Fructans

In experimental probiotic psychobiotics, the bacteria most commonly used are gram-positive bacteria, such as Bifidobacterium and Lactobacillus families, as these do not contain lipopolysaccharide chains, reducing the likelihood of an immunological response.[1] Prebiotics are substances, such as fructans and oligosaccharides, that induce the growth or activity of beneficial microorganisms, such as bacteria on being fermented in the gut.[1][5] Multiple bacterial species contained in a single probiotic broth is known as a polybiotic.[6]

Research edit

A 2021 review showed that treating anxiety in young people with psychobiotics had no significant effect.[7] There is a need for more diverse human studies, mainly because those that exist have contradictory outcomes.[3][4][7]

Species edit

 
Lactobacillus acidophilus

Several species of bacteria have been used in probiotic psychobiotic research:[6][8]

References edit

  1. ^ a b c Sarkar A, Lehto SM, Harty S, Dinan TG, Cryan JF, Burnet PW (November 2016). "Psychobiotics and the Manipulation of Bacteria-Gut-Brain Signals". Trends in Neurosciences. 39 (11): 763–81. doi:10.1016/j.tins.2016.09.002. PMC 5102282. PMID 27793434.
  2. ^ Del Toro-Barbosa, M.; Hurtado-Romero, A.; Garcia-Amezquita, L. E.; García-Cayuela, T. (2020). "Psychobiotics: Mechanisms of Action, Evaluation Methods and Effectiveness in Applications with Food Products". Nutrients. 12 (12): 3896. doi:10.3390/nu12123896. PMC 7767237. PMID 33352789.
  3. ^ a b Romijn AR, Rucklidge JJ (October 2015). "Systematic review of evidence to support the theory of psychobiotics". Nutrition Reviews. 73 (10): 675–93. doi:10.1093/nutrit/nuv025. PMID 26370263.
  4. ^ a b Liu B, He Y, Wang M, Liu J, Ju Y, Zhang Y, Liu T, Li L, Li Q (July 2018). "Efficacy of probiotics on anxiety-A meta-analysis of randomized controlled trials". Depression and Anxiety. 35 (10): 935–45. doi:10.1002/da.22811. PMID 29995348. S2CID 51615532.
  5. ^ Hutkins RW, Krumbeck JA, Bindels LB, Cani PD, Fahey G, Goh YJ, Hamaker B, Martens EC, Mills DA, Rastal RA, Vaughan E, Sanders ME (February 2016). "Prebiotics: why definitions matter". Current Opinion in Biotechnology. 37: 1–7. doi:10.1016/j.copbio.2015.09.001. PMC 4744122. PMID 26431716.
  6. ^ a b Bambury A, Sandhu K, Cryan JF, Dinan TG (December 2018). "Finding the needle in the haystack: systematic identification of psychobiotics". British Journal of Pharmacology. 175 (24): 4430–38. doi:10.1111/bph.14127. PMC 6255950. PMID 29243233.
  7. ^ a b Cohen Kadosh, Kathrin; Basso, Melissa; Knytl, Paul; Johnstone, Nicola; Lau, Jennifer Y. F.; Gibson, Glenn R. (2021-06-16). "Psychobiotic interventions for anxiety in young people: a systematic review and meta-analysis, with youth consultation". Translational Psychiatry. 11 (1): 352. doi:10.1038/s41398-021-01422-7. ISSN 2158-3188. PMC 8206413. PMID 34131108.
  8. ^ Dinan TG, Stanton C, Cryan JF (November 2013). "Psychobiotics: a novel class of psychotropic". Biological Psychiatry. 74 (10): 720–26. doi:10.1016/j.biopsych.2013.05.001. PMID 23759244. S2CID 40059439.

Further reading edit

  • Anderson, Scott C.; Cryan, John F.; Dinan, Ted (17 December 2019). The Psychobiotic Revolution (1 ed.). Random House US. ISBN 9781426219641.

psychobiotic, this, article, needs, more, reliable, medical, references, verification, relies, heavily, primary, sources, please, review, contents, article, appropriate, references, unsourced, poorly, sourced, material, challenged, removed, find, sources, news. This article needs more reliable medical references for verification or relies too heavily on primary sources Please review the contents of the article and add the appropriate references if you can Unsourced or poorly sourced material may be challenged and removed Find sources Psychobiotic news newspapers books scholar JSTOR December 2018 Psychobiotics is a term used in preliminary research to refer to live bacteria that when ingested in appropriate amounts might confer a mental health benefit by affecting microbiota of the host organism 1 Whether bacteria might play a role in the gut brain axis is under research A 2020 literature review suggests that the consumption of psychobiotics could be considered as a viable option to restore mental health 2 although lacking randomized controlled trials on clear mental health outcomes in humans 3 4 Contents 1 Types 2 Research 2 1 Species 3 References 4 Further readingTypes edit nbsp Fructans In experimental probiotic psychobiotics the bacteria most commonly used are gram positive bacteria such as Bifidobacterium and Lactobacillus families as these do not contain lipopolysaccharide chains reducing the likelihood of an immunological response 1 Prebiotics are substances such as fructans and oligosaccharides that induce the growth or activity of beneficial microorganisms such as bacteria on being fermented in the gut 1 5 Multiple bacterial species contained in a single probiotic broth is known as a polybiotic 6 Research editA 2021 review showed that treating anxiety in young people with psychobiotics had no significant effect 7 There is a need for more diverse human studies mainly because those that exist have contradictory outcomes 3 4 7 Species edit nbsp Lactobacillus acidophilus Several species of bacteria have been used in probiotic psychobiotic research 6 8 Lactobacillus helveticus Bifidobacterium longum Lactobacillus casei Lactobacillus plantarum Lactobacillus acidophilus Lactobacillus delbrueckii subsp bulgaricus Bifidobacterium breve Bifidobacterium infantis Streptococcus salivarius Lactobacillus rhamnosus Lactobacillus gasseriReferences edit a b c Sarkar A Lehto SM Harty S Dinan TG Cryan JF Burnet PW November 2016 Psychobiotics and the Manipulation of Bacteria Gut Brain Signals Trends in Neurosciences 39 11 763 81 doi 10 1016 j tins 2016 09 002 PMC 5102282 PMID 27793434 Del Toro Barbosa M Hurtado Romero A Garcia Amezquita L E Garcia Cayuela T 2020 Psychobiotics Mechanisms of Action Evaluation Methods and Effectiveness in Applications with Food Products Nutrients 12 12 3896 doi 10 3390 nu12123896 PMC 7767237 PMID 33352789 a b Romijn AR Rucklidge JJ October 2015 Systematic review of evidence to support the theory of psychobiotics Nutrition Reviews 73 10 675 93 doi 10 1093 nutrit nuv025 PMID 26370263 a b Liu B He Y Wang M Liu J Ju Y Zhang Y Liu T Li L Li Q July 2018 Efficacy of probiotics on anxiety A meta analysis of randomized controlled trials Depression and Anxiety 35 10 935 45 doi 10 1002 da 22811 PMID 29995348 S2CID 51615532 Hutkins RW Krumbeck JA Bindels LB Cani PD Fahey G Goh YJ Hamaker B Martens EC Mills DA Rastal RA Vaughan E Sanders ME February 2016 Prebiotics why definitions matter Current Opinion in Biotechnology 37 1 7 doi 10 1016 j copbio 2015 09 001 PMC 4744122 PMID 26431716 a b Bambury A Sandhu K Cryan JF Dinan TG December 2018 Finding the needle in the haystack systematic identification of psychobiotics British Journal of Pharmacology 175 24 4430 38 doi 10 1111 bph 14127 PMC 6255950 PMID 29243233 a b Cohen Kadosh Kathrin Basso Melissa Knytl Paul Johnstone Nicola Lau Jennifer Y F Gibson Glenn R 2021 06 16 Psychobiotic interventions for anxiety in young people a systematic review and meta analysis with youth consultation Translational Psychiatry 11 1 352 doi 10 1038 s41398 021 01422 7 ISSN 2158 3188 PMC 8206413 PMID 34131108 Dinan TG Stanton C Cryan JF November 2013 Psychobiotics a novel class of psychotropic Biological Psychiatry 74 10 720 26 doi 10 1016 j biopsych 2013 05 001 PMID 23759244 S2CID 40059439 Further reading editAnderson Scott C Cryan John F Dinan Ted 17 December 2019 The Psychobiotic Revolution 1 ed Random House US ISBN 9781426219641 Retrieved from https en wikipedia org w index php title Psychobiotic amp oldid 1218710121, wikipedia, wiki, book, books, library,

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