The phylogenetic analyses of the few genes that are still encoded in the genomes of modern mitochondria suggest an alphaproteobacterial origin for this endosymbiont, in an ancient episode of symbiogenesis early in the history of the eukaryotes. Although the order Rickettsiales has been proposed as the alphaproteobacterial sister-group of mitochondria, there is no definitive evidence as to which alphaproteobacterial group the proto-mitochondrion emerged from. Martijn et al found mitochondria are a possible sister-group to all other alphaproteobacteria.[1] The phylogenetic tree of the Rickettsidae has been inferred by Ferla et al. from the comparison of 16S + 23S ribosomal RNA sequences.[2]
Toni Gabaldón and Martijn Huynen (2003) reconstructed the proteome (the entire set of proteins expressed by a genome) and corresponding metabolism of the proto-mitochondrion by comparing extant alpha-proteobacterial and eukaryotic genomes. They concluded that this organism was an aerobic alpha-proteobacterium respiring lipids, glycerol and other compounds provided by the host. At least 630 gene families derived from this organism can still be found in the 9 eukaryotic genomes analyzed in the study.[3]
^Ferla, Mattep P.; Thrash, J. Cameron; Giovannoni, Stephen J.; Patrick, Wayne M. (2013). "New rRNA gene-based phylogenies of the Alphaproteobacteria provide perspective on major groups, mitochondrial ancestry and phylogenetic instability". PLOS ONE. 8 (12): e83383. Bibcode:2013PLoSO...883383F. doi:10.1371/journal.pone.0083383. PMC3859672. PMID 24349502.
^Gabaldón, Toni; Huynen, Martijn A. (2003). "The proto-mitochondrial metabolism". Science. 301 (5633): 690. doi:10.1126/science.1085463. PMID 12893934. S2CID 28868747.
January 01, 1970
proto, mitochondrion, proto, mitochondrion, hypothetical, ancestral, bacterial, endosymbiont, from, which, mitochondria, eukaryotes, thought, descend, after, episode, symbiogenesis, which, created, aerobic, eukaryotes, scientific, classification, domain, bacte. The proto mitochondrion is the hypothetical ancestral bacterial endosymbiont from which all mitochondria in eukaryotes are thought to descend after an episode of symbiogenesis which created the aerobic eukaryotes Proto mitochondrion Scientific classification Domain Bacteria Phylum Pseudomonadota Class Alphaproteobacteria or sister to Order Rickettsiales Contents 1 Phylogeny 2 Metabolism 3 See also 4 ReferencesPhylogeny editThe phylogenetic analyses of the few genes that are still encoded in the genomes of modern mitochondria suggest an alphaproteobacterial origin for this endosymbiont in an ancient episode of symbiogenesis early in the history of the eukaryotes Although the order Rickettsiales has been proposed as the alphaproteobacterial sister group of mitochondria there is no definitive evidence as to which alphaproteobacterial group the proto mitochondrion emerged from Martijn et al found mitochondria are a possible sister group to all other alphaproteobacteria 1 The phylogenetic tree of the Rickettsidae has been inferred by Ferla et al from the comparison of 16S 23S ribosomal RNA sequences 2 Alphaproteobacteria Magnetococcidae Magnetococcus marinus Caulobacteridae Rhodospirillales Sphingomonadales Rhodobacteraceae Hyphomicrobiales etc Holosporales Rickettsidae Pelagibacterales Pelagibacteraceae Pelagibacter Subgroups Ib II IIIa IIIb IV and V Rickettsiales Proto mitochondria Anaplasmataceae Ehrlichia Anaplasma Wolbachia Neorickettsia Midichloriaceae Midichloria Rickettsiaceae Rickettsia OrientiaMetabolism editToni Gabaldon and Martijn Huynen 2003 reconstructed the proteome the entire set of proteins expressed by a genome and corresponding metabolism of the proto mitochondrion by comparing extant alpha proteobacterial and eukaryotic genomes They concluded that this organism was an aerobic alpha proteobacterium respiring lipids glycerol and other compounds provided by the host At least 630 gene families derived from this organism can still be found in the 9 eukaryotic genomes analyzed in the study 3 See also editAbiogenesis Endosymbiotic theory Hydrogenosome Midichloria Protocell RickettsialesReferences edit Martijn Joran Vosseberg Julian Guy Lionel Offre Pierre Ettema Thijs J G 2018 Deep mitochondrial origin outside the sampled alphaproteobacteria Nature 557 7703 101 105 Bibcode 2018Natur 557 101M doi 10 1038 s41586 018 0059 5 ISSN 0028 0836 PMID 29695865 S2CID 13740626 Ferla Mattep P Thrash J Cameron Giovannoni Stephen J Patrick Wayne M 2013 New rRNA gene based phylogenies of the Alphaproteobacteria provide perspective on major groups mitochondrial ancestry and phylogenetic instability PLOS ONE 8 12 e83383 Bibcode 2013PLoSO 883383F doi 10 1371 journal pone 0083383 PMC 3859672 PMID 24349502 Gabaldon Toni Huynen Martijn A 2003 The proto mitochondrial metabolism Science 301 5633 690 doi 10 1126 science 1085463 PMID 12893934 S2CID 28868747 Retrieved from https en wikipedia org w index php title Proto mitochondrion amp oldid 1216274465, wikipedia, wiki, book, books, library,
