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Wikipedia

Propanamide

Propanamide has the chemical formula CH3CH2C=O(NH2).[1] It is the amide of propanoic acid.

Propanamide
Skeletal formula
Ball-and-stick model
Names
Preferred IUPAC name
Propanamide
Other names
n-propylamide
Propionamide
Propylamide
Propionic amide
Identifiers
  • 79-05-0 Y
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:45422 N
ChemSpider
  • 6330 N
ECHA InfoCard 100.001.066
EC Number
  • 201-182-6
MeSH C034666
  • 6578
UNII
  • QK07G0HP47 Y
  • DTXSID3058820
  • InChI=1S/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5) N
    Key: QLNJFJADRCOGBJ-UHFFFAOYSA-N N
  • InChI=1/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5)
    Key: QLNJFJADRCOGBJ-UHFFFAOYAE
  • CCC(=O)N
Properties
C3H7NO
Molar mass 73.095 g·mol−1
Appearance liquid , yellow
Density 1.042 g/mL
Melting point 80 °C (176 °F; 353 K)
Boiling point 213 °C (415 °F; 486 K)
very soluble in water
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)

This organic compound is a mono-substituted amide.[2] Organic compounds of the amide group can react in many different organic processes to form other useful compounds for synthesis.

Preparation edit

Propanamide can be prepared by the condensation reaction between urea and propanoic acid:

 

or by the dehydration of ammonium propionate:

 

Reactions edit

Propanamide being an amide can participate in a Hoffman rearrangement to produce ethylamine gas.

References edit

  1. ^ Ramazani, Ali; Rouhani, Morteza; Joo, Sang Woo (2016-01-01). "Catalyst-free sonosynthesis of highly substituted propanamide derivatives in water". Ultrasonics Sonochemistry. 28: 393–399. doi:10.1016/j.ultsonch.2015.08.019. ISSN 1350-4177. PMID 26384923.
  2. ^ Ye, Xuewei; Chai, Weiyun; Lian, Xiao-Yuan; Zhang, Zhizhen (2017-06-18). "Novel propanamide analogue and antiproliferative diketopiperazines from mangrove Streptomyces sp. Q24". Natural Product Research. 31 (12): 1390–1396. doi:10.1080/14786419.2016.1253079. ISSN 1478-6419. PMID 27806640. S2CID 24563632.

propanamide, chemical, formula, ch3ch2c, amide, propanoic, acid, skeletal, formula, ball, stick, modelnamespreferred, iupac, name, other, names, propylamidepropionamidepropylamidepropionic, amideidentifierscas, number, model, jsmol, interactive, imagechebi, ch. Propanamide has the chemical formula CH3CH2C O NH2 1 It is the amide of propanoic acid Propanamide Skeletal formula Ball and stick modelNamesPreferred IUPAC name PropanamideOther names n propylamidePropionamidePropylamidePropionic amideIdentifiersCAS Number 79 05 0 Y3D model JSmol Interactive imageChEBI CHEBI 45422 NChemSpider 6330 NECHA InfoCard 100 001 066EC Number 201 182 6MeSH C034666PubChem CID 6578UNII QK07G0HP47 YCompTox Dashboard EPA DTXSID3058820InChI InChI 1S C3H7NO c1 2 3 4 5 h2H2 1H3 H2 4 5 NKey QLNJFJADRCOGBJ UHFFFAOYSA N NInChI 1 C3H7NO c1 2 3 4 5 h2H2 1H3 H2 4 5 Key QLNJFJADRCOGBJ UHFFFAOYAESMILES CCC O NPropertiesChemical formula C 3H 7N OMolar mass 73 095 g mol 1Appearance liquid yellowDensity 1 042 g mLMelting point 80 C 176 F 353 K Boiling point 213 C 415 F 486 K Solubility in water very soluble in waterExcept where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa N verify what is Y N Infobox references This organic compound is a mono substituted amide 2 Organic compounds of the amide group can react in many different organic processes to form other useful compounds for synthesis Preparation editPropanamide can be prepared by the condensation reaction between urea and propanoic acid NH2 2CO 2CH3CH2COOH CH3CH2CO NH2 H2O CO2 displaystyle ce NH2 2CO 2CH3CH2COOH gt CH3CH2CO NH2 H2O CO2 nbsp or by the dehydration of ammonium propionate NH4 CH3CH2COO CH3CH2CONH2 H2O displaystyle ce NH4 CH3CH2COO gt CH3CH2CONH2 H2O nbsp Reactions editPropanamide being an amide can participate in a Hoffman rearrangement to produce ethylamine gas References edit Ramazani Ali Rouhani Morteza Joo Sang Woo 2016 01 01 Catalyst free sonosynthesis of highly substituted propanamide derivatives in water Ultrasonics Sonochemistry 28 393 399 doi 10 1016 j ultsonch 2015 08 019 ISSN 1350 4177 PMID 26384923 Ye Xuewei Chai Weiyun Lian Xiao Yuan Zhang Zhizhen 2017 06 18 Novel propanamide analogue and antiproliferative diketopiperazines from mangrove Streptomyces sp Q24 Natural Product Research 31 12 1390 1396 doi 10 1080 14786419 2016 1253079 ISSN 1478 6419 PMID 27806640 S2CID 24563632 nbsp This article about an organic compound is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Propanamide amp oldid 1200232176, wikipedia, wiki, book, books, library,

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