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SL-75102

SL-75102, or progabide acid, is an active metabolite of progabide and an anticonvulsant GABA receptor agonist.[1][2]

SL-75102
Names
IUPAC name
4-[[(4-Chlorophenyl)-(3-fluoro-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]butanoic acid
Other names
Progabide acid; LS-187121; SL-75-102-00
Identifiers
  • 62665-97-8 Y
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:368340
ChEMBL
  • ChEMBL160058
ChemSpider
  • 20121433
  • 6140507
UNII
  • 74JC6VM0KD Y
  • InChI=1S/C17H15ClFNO3/c18-12-5-3-11(4-6-12)17(20-9-1-2-16(22)23)14-10-13(19)7-8-15(14)21/h3-8,10,21H,1-2,9H2,(H,22,23)/b20-17+
    Key: RRAXPPHKWFOGGL-LVZFUZTISA-N
  • c1cc(ccc1/C(=N\CCCC(=O)O)/c2cc(ccc2O)F)Cl
Properties
C17H15ClFNO3
Molar mass 335.76 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References edit

  1. ^ Hamberger, C.; Barre, J.; Brandebourger, M.; Urien, S.; Taiclet, A.; Thenot, J. P.; Tillement, J. P. (April 1987). "Progabide and SL 75102 binding to plasma proteins and red blood cells in humans". Int J Clin Pharmacol Ther Toxicol. 25 (4): 178–84. PMID 3583466.
  2. ^ Kubová, H.; Haugvicová, R.; Mares, P. (1997). "Anticonvulsant effect of SL 75 102 in adult and immature rats". Physiol Res. 46 (1): 73–6. PMID 9728525.


75102, progabide, acid, active, metabolite, progabide, anticonvulsant, gaba, receptor, agonist, namesiupac, name, chlorophenyl, fluoro, oxocyclohexa, dien, ylidene, methyl, amino, butanoic, acidother, names, progabide, acid, 187121, 00identifierscas, number, 6. SL 75102 or progabide acid is an active metabolite of progabide and an anticonvulsant GABA receptor agonist 1 2 SL 75102 NamesIUPAC name 4 4 Chlorophenyl 3 fluoro 6 oxocyclohexa 2 4 dien 1 ylidene methyl amino butanoic acidOther names Progabide acid LS 187121 SL 75 102 00IdentifiersCAS Number 62665 97 8 Y3D model JSmol Interactive imageChEBI CHEBI 368340ChEMBL ChEMBL160058ChemSpider 20121433PubChem CID 6140507UNII 74JC6VM0KD YInChI InChI 1S C17H15ClFNO3 c18 12 5 3 11 4 6 12 17 20 9 1 2 16 22 23 14 10 13 19 7 8 15 14 21 h3 8 10 21H 1 2 9H2 H 22 23 b20 17 Key RRAXPPHKWFOGGL LVZFUZTISA NSMILES c1cc ccc1 C N CCCC O O c2cc ccc2O F ClPropertiesChemical formula C 17H 15Cl F N O 3Molar mass 335 76 g mol 1Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Infobox referencesReferences edit Hamberger C Barre J Brandebourger M Urien S Taiclet A Thenot J P Tillement J P April 1987 Progabide and SL 75102 binding to plasma proteins and red blood cells in humans Int J Clin Pharmacol Ther Toxicol 25 4 178 84 PMID 3583466 Kubova H Haugvicova R Mares P 1997 Anticonvulsant effect of SL 75 102 in adult and immature rats Physiol Res 46 1 73 6 PMID 9728525 nbsp This anticonvulsant related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title SL 75102 amp oldid 1169638209, wikipedia, wiki, book, books, library,

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