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Perfluoropentane

Perfluoropentane (PFP) or dodecafluoropentane; also known as Perflenapent (INN/USAN) is a fluorocarbon, the fluorinated analogue of pentane. It is a liquid that boils at slightly over room temperature.

Perfluoropentane
Names
Preferred IUPAC name
Dodecafluoropentane[1]
Other names
Perfluoropentane
Identifiers
  • 678-26-2
3D model (JSmol)
  • Interactive image
1712388
ChEBI
  • CHEBI:39428
ChEMBL
  • ChEMBL1899801
ChemSpider
  • 12154
ECHA InfoCard 100.010.589
EC Number
  • 211-647-5
KEGG
  • D05436
  • 12675
UNII
  • 483AU1Y5CZ
  • DTXSID3046613
  • InChI=1S/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17
    Key: NJCBUSHGCBERSK-UHFFFAOYSA-N
  • InChI=1/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17
    Key: NJCBUSHGCBERSK-UHFFFAOYAH
  • C(C(C(F)(F)F)(F)F)(C(C(F)(F)F)(F)F)(F)F
Properties
C5F12
Molar mass 288.036 g·mol−1
Density 1.63 g/mL (liquid, 25 °C) [2]
1.59 g/mL (liquid, 35 °C)
12.25 kg/m³ (gas, 1 atm, 10 times air density)
Melting point −115 °C (−175 °F; 158 K)
Boiling point 28 °C (82 °F; 301 K)
Heat of vaporization = 21 cal/g
Vapor pressure 83.99 kPa (25 °C)
Viscosity 0.652 mPa*s (25 °C)
Thermochemistry
0.26 cal/(g • K)
Pharmacology
V08DA03 (WHO)
Hazards
GHS labelling:
Warning
H315, H319, H335
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

It has several biomedical applications including: propellant for pressurized metered dose inhalers;[3] gas core in microbubble ultrasound contrast agents;[4] and occlusion therapy via the conversion of nanometer liquid droplets into micrometer sized gas microbubbles (acoustic droplet vaporization).[5]

References edit

  1. ^ "Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 33. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The prefix 'per-' is no longer recommended.
  2. ^ "Perfluoropentane". Retrieved September 26, 2023.
  3. ^ Rogueda, P. G. A. HPFP, a Model Propellant for pMDIs. Drug Dev. Ind. Phar. 2003, 29, 39
  4. ^ Liu, Y., Miyoshi, H., and Nakamura, M. Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery. J. Controlled Release 2006, 114, 89− 99
  5. ^ D. Bardin, T. D. Martz, P. S. Sheeran, R. Shih, P. A. Dayton, and A. P. Lee, “High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy,” Lab on a Chip, vol. 11, no. 23, p. 3990, 2011.

perfluoropentane, dodecafluoropentane, also, known, perflenapent, usan, fluorocarbon, fluorinated, analogue, pentane, liquid, that, boils, slightly, over, room, temperature, namespreferred, iupac, name, dodecafluoropentane, other, names, identifierscas, number. Perfluoropentane PFP or dodecafluoropentane also known as Perflenapent INN USAN is a fluorocarbon the fluorinated analogue of pentane It is a liquid that boils at slightly over room temperature Perfluoropentane NamesPreferred IUPAC name Dodecafluoropentane 1 Other names PerfluoropentaneIdentifiersCAS Number 678 26 23D model JSmol Interactive imageBeilstein Reference 1712388ChEBI CHEBI 39428ChEMBL ChEMBL1899801ChemSpider 12154ECHA InfoCard 100 010 589EC Number 211 647 5KEGG D05436PubChem CID 12675UNII 483AU1Y5CZCompTox Dashboard EPA DTXSID3046613InChI InChI 1S C5F12 c6 1 7 2 8 9 4 12 13 14 3 10 11 5 15 16 17Key NJCBUSHGCBERSK UHFFFAOYSA NInChI 1 C5F12 c6 1 7 2 8 9 4 12 13 14 3 10 11 5 15 16 17Key NJCBUSHGCBERSK UHFFFAOYAHSMILES C C C F F F F F C C F F F F F F FPropertiesChemical formula C 5F 12Molar mass 288 036 g mol 1Density 1 63 g mL liquid 25 C 2 1 59 g mL liquid 35 C 12 25 kg m gas 1 atm 10 times air density Melting point 115 C 175 F 158 K Boiling point 28 C 82 F 301 K Heat of vaporization 21 cal gVapor pressure 83 99 kPa 25 C Viscosity 0 652 mPa s 25 C ThermochemistryHeat capacity C 0 26 cal g K PharmacologyATC code V08DA03 WHO HazardsGHS labelling PictogramsSignal word WarningHazard statements H315 H319 H335Precautionary statements P261 P264 P271 P280 P302 P352 P304 P340 P305 P351 P338 P312 P321 P332 P313 P337 P313 P362 P403 P233 P405 P501Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Infobox references It has several biomedical applications including propellant for pressurized metered dose inhalers 3 gas core in microbubble ultrasound contrast agents 4 and occlusion therapy via the conversion of nanometer liquid droplets into micrometer sized gas microbubbles acoustic droplet vaporization 5 References edit Front Matter Nomenclature of Organic Chemistry IUPAC Recommendations and Preferred Names 2013 Blue Book Cambridge The Royal Society of Chemistry 2014 p 33 doi 10 1039 9781849733069 FP001 ISBN 978 0 85404 182 4 The prefix per is no longer recommended Perfluoropentane Retrieved September 26 2023 Rogueda P G A HPFP a Model Propellant for pMDIs Drug Dev Ind Phar 2003 29 39 Liu Y Miyoshi H and Nakamura M Encapsulated ultrasound microbubbles Therapeutic application in drug gene delivery J Controlled Release 2006 114 89 99 D Bardin T D Martz P S Sheeran R Shih P A Dayton and A P Lee High speed clinical scale microfluidic generation of stable phase change droplets for gas embolotherapy Lab on a Chip vol 11 no 23 p 3990 2011 nbsp This pharmacology related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Perfluoropentane amp oldid 1182789002, wikipedia, wiki, book, books, library,

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