Paul Bargehr (18 March 1889– 31 December 1951) was an Austrianmedical doctor and writer mostly known for his work treating Hansen's disease (leprosy) in the Dutch East Indies (now Indonesia). Although the Japanese researcher Kensuke Mitsuda receives credit for first developing the modern lepromin test for distinguishing between different forms of Hansen's disease, Bargehr's work was responsible for coining and popularizing its current name.
Paul Bargehr was born on 18 March 1889 in Thüringen, Vorarlberg, in Austria-Hungary.[1] He practised medicine in Innsbruck before travelling to the island of Java in the Dutch East Indies in 1920.[1] While there, he studied and treated Hansen's disease,[1] developing a modified form of intradermal leprolin test. He minced leproma with a large amount of M. leprae in water, then boiled it at 100°C for 20 minutes and added carbolic acid at a ratio of 1:200 with the water.[2] He called the serum thus created "lepromin",[3] which has remained the common name for such tests.[4] He changed the name to avoid confusion with the tuberculin test for tuberculosis and also to clarify that the antigen was made from lepromatuous tissue.[5] He was heavily decried, however, for exposing healthy subjects to the leprosy bacillus in his experiments.[6] Bargehr returned to Austria in 1928, working at the Zeileis Institute in Gallspach, Upper Austria.[1] He began his own Zeileis practice in Munich in 1929 but had to close it the next year owing to debt.[1] He completed a manuscript entitled New Foundations of Physics (German: Neue Grundlagen der Physik) in 1945, but was unable to find a publisher.[1] He died in Gallspach on 31 December 1951.[1] His work and correspondence are held by the University of Innsbruck.[1]
Worksedit
This list is incomplete; you can help by adding missing items. (May 2022)
"Die Selbstheilung der Lepra [Self-Healing of Leprosy]", Geneeskundig Tijdschrift voor Nederlandsch-Indië, Jakarta: Lange & Co., no. 66, pp. 603–609, 1926. (German)
"Spezifische Hautreacktionen bei Lepra [Specific Skin Reaction in Leprosy]", Zeitschrift für Immunitätsforschung und Experimentalle Therapie, Stuttgart: Fischer, no. 47, pp. 529–531, 1926. (German)
"Zur Leprafrage [On the Leprosy Question]", Münchener Medizinische Wochenschrift, vol. 1, no. 82, p. 56, 1935. (German)
"Paul Bargehr", Personenlexikon, Vienna: Austrian National Library, April 2009. (German)
"Paul Bargehr", Forschungsinstitut Brenner-Archiv, Innsbruck: University of Innsbruck, 2020. (German)
Feldman, William H.; et al. (March 1951), "Lepromin: Mitsuda's Reaction with Experimental Observations in Dogs", Annals of the New York Academy of Sciences, New York City: NYAS, 54 (1): 53–72, Bibcode:1951NYASA..54...53F, doi:10.1111/j.1749-6632.1951.tb45832.x.
Pan, C.S. (December 1942), "A Clinical Evaluation of the Lepromin Test", Archives of Dermatology and Syphilology, Chicago: American Medical Association, vol. 46, no. 6, p. 792-795, doi:10.1001/archderm.1942.01500180012002.
Rogers, Leonard (October 1930), "The Intradermal Leprolin Test for the Detection of Early and Latent Leprosy" (PDF), Leprosy Review, London: BELRA, vol. 1, no. 4, pp. 9–11.
Van Bergen, Leo (2018), Uncertainty, Anxiety, Frugality: Dealing with Leprosy in the Dutch East Indies, 1816–1942, Singapore: National University of Singapore Press, ISBN9789814722834.
Wade, Herbert Windsor (13 November 1961), "Preparation of Lepromin or the Mitsuda Antigen" (PDF), Report on the First Inter-regional Postgraduate Leprosy Training Course, Manila: World Health Organization Regional Office for the Western Pacific.
March 01, 2024
paul, bargehr, march, 1889, december, 1951, austrian, medical, doctor, writer, mostly, known, work, treating, hansen, disease, leprosy, dutch, east, indies, indonesia, although, japanese, researcher, kensuke, mitsuda, receives, credit, first, developing, moder. Paul Bargehr 18 March 1889 31 December 1951 was an Austrian medical doctor and writer mostly known for his work treating Hansen s disease leprosy in the Dutch East Indies now Indonesia Although the Japanese researcher Kensuke Mitsuda receives credit for first developing the modern lepromin test for distinguishing between different forms of Hansen s disease Bargehr s work was responsible for coining and popularizing its current name Paul BargehrBorn 1889 03 18 18 March 1889Thuringen VorarlbergDied31 December 1951 1951 12 31 aged 62 GallspachNationalityAustrianOccupationmedical doctorKnown forLeprosy researches pathology Contents 1 Life 2 Works 3 References 3 1 Citations 3 2 BibliographyLife editPaul Bargehr was born on 18 March 1889 in Thuringen Vorarlberg in Austria Hungary 1 He practised medicine in Innsbruck before travelling to the island of Java in the Dutch East Indies in 1920 1 While there he studied and treated Hansen s disease 1 developing a modified form of intradermal leprolin test He minced leproma with a large amount of M leprae in water then boiled it at 100 C for 20 minutes and added carbolic acid at a ratio of 1 200 with the water 2 He called the serum thus created lepromin 3 which has remained the common name for such tests 4 He changed the name to avoid confusion with the tuberculin test for tuberculosis and also to clarify that the antigen was made from lepromatuous tissue 5 He was heavily decried however for exposing healthy subjects to the leprosy bacillus in his experiments 6 Bargehr returned to Austria in 1928 working at the Zeileis Institute in Gallspach Upper Austria 1 He began his own Zeileis practice in Munich in 1929 but had to close it the next year owing to debt 1 He completed a manuscript entitled New Foundations of Physics German Neue Grundlagen der Physik in 1945 but was unable to find a publisher 1 He died in Gallspach on 31 December 1951 1 His work and correspondence are held by the University of Innsbruck 1 Works editThis list is incomplete you can help by adding missing items May 2022 Die Selbstheilung der Lepra Self Healing of Leprosy Geneeskundig Tijdschrift voor Nederlandsch Indie Jakarta Lange amp Co no 66 pp 603 609 1926 German Spezifische Hautreacktionen bei Lepra Specific Skin Reaction in Leprosy Zeitschrift fur Immunitatsforschung und Experimentalle Therapie Stuttgart Fischer no 47 pp 529 531 1926 German Zur Leprafrage On the Leprosy Question Munchener Medizinische Wochenschrift vol 1 no 82 p 56 1935 German References editCitations edit a b c d e f g h Univ Innsbruck 2020 Rogers 1930 p 9 Feldman amp al 1951 p 53 Wade 1961 p 1 Pan 1942 p 792 Van Bergen 2018 p 210 Bibliography edit Paul Bargehr Personenlexikon Vienna Austrian National Library April 2009 German Paul Bargehr Forschungsinstitut Brenner Archiv Innsbruck University of Innsbruck 2020 German Feldman William H et al March 1951 Lepromin Mitsuda s Reaction with Experimental Observations in Dogs Annals of the New York Academy of Sciences New York City NYAS 54 1 53 72 Bibcode 1951NYASA 54 53F doi 10 1111 j 1749 6632 1951 tb45832 x Pan C S December 1942 A Clinical Evaluation of the Lepromin Test Archives of Dermatology and Syphilology Chicago American Medical Association vol 46 no 6 p 792 795 doi 10 1001 archderm 1942 01500180012002 Rogers Leonard October 1930 The Intradermal Leprolin Test for the Detection of Early and Latent Leprosy PDF Leprosy Review London BELRA vol 1 no 4 pp 9 11 Van Bergen Leo 2018 Uncertainty Anxiety Frugality Dealing with Leprosy in the Dutch East Indies 1816 1942 Singapore National University of Singapore Press ISBN 9789814722834 Wade Herbert Windsor 13 November 1961 Preparation of Lepromin or the Mitsuda Antigen PDF Report on the First Inter regional Postgraduate Leprosy Training Course Manila World Health Organization Regional Office for the Western Pacific Retrieved from https en wikipedia org w index php title Paul Bargehr amp oldid 1177387722, wikipedia, wiki, book, books, library,
