In 1917, Northrop married Louise Walker (1891–1975), with whom he had two children: John, an oceanographer, and Alice, who married Nobel laureate Frederick C. Robbins. The family lived in a small home just outside of Mt. Vernon, New York. As their children grew older and Northrop looked for a more desirable workplace, the family bought a home in Cotuit, Massachusetts. This move shortened Northrop's commute to the laboratory in Princeton, New Jersey, and also put him in closer contact with the wilderness which he greatly enjoyed.[11] Northrop committed suicide in Wickenburg, Arizona in 1987.[12]
Referencesedit
^"The Nobel Prize in Chemistry 1946 – Preparing Pure Proteins". Retrieved December 14, 2008.
^"Alexander Hamilton Medal". Columbia College Alumni Association. December 14, 2016. Retrieved June 24, 2022.
^Columbia College (Columbia University). Office of Alumni Affairs and Development; Columbia College (Columbia University) (1960–1961). Columbia College today. Columbia University Libraries. New York, N.Y. : Columbia College, Office of Alumni Affairs and Development.
^Northrop, J. H. (1929), "Crystalline Pepsin", Science, 69 (1796): 580, Bibcode:1929Sci....69..580N, doi:10.1126/science.69.1796.580, PMID 17758437
^"John H. Northrop". www.nasonline.org. Retrieved May 19, 2023.
^"APS Member History". search.amphilsoc.org. Retrieved May 19, 2023.
^. National Academy of Sciences. Archived from the original on December 29, 2010. Retrieved February 16, 2011.
^"Book of Members, 1780–2010: Chapter N" (PDF). American Academy of Arts and Sciences. Retrieved April 15, 2011.
^"John H. Northrop – Biographical". Nobel Foundation. Retrieved April 29, 2017.
^See p. 440 of Herriott, R. M. (1994), "John Howard Northrop: July 5, 1891 – May 27, 1987", Biographical Memoirs. National Academy of Sciences (U.S.), vol. 63, pp. 423–450, PMID 11615389
Further readingedit
Economos, A. C.; Lints, F. A. (1985), "Growth rate and life span in Drosophila V. The effect of prolongation of the period of growth on the total duration of life (J.H. Northrop, 1917) – revisited", Mech. Ageing Dev. (published December 1985), vol. 33, no. 1, pp. 103–113, doi:10.1016/0047-6374(85)90112-5, PMID 3908838, S2CID 23576391
Herriott, R. M. (1981), "John Howard Northrop", J. Gen. Physiol. (published June 1981), vol. 77, no. 6, pp. 597–599, doi:10.1085/jgp.77.6.597, PMC2215443, PMID 7021760
Herriott, R. M. (1994), "John Howard Northrop: July 5, 1891 – May 27, 1987", Biographical Memoirs. National Academy of Sciences (U.S.), vol. 63, pp. 423–450, PMID 11615389
See also this version of Northrop's National Academy of Science biography.
Northrop, J. H. (1939), Crystalline Enzymes, Columbia University Press
Shampo, M A; Kyle, R. A. (2000), "John Northrop – definitive study of enzymes", Mayo Clin. Proc. (published March 2000), vol. 75, no. 3, p. 254, doi:10.4065/75.3.254, PMID 10725951
van Helvoort, T. (1992), "The controversy between John H. Northrop and Max Delbrück on the formation of bacteriophage: bacterial synthesis or autonomous multiplication?", Annals of Science (published November 1992), vol. 49, no. 6, pp. 545–575, doi:10.1080/00033799200200451, PMID 11616207
John Howard Northrop on Nobelprize.org including the Nobel Lecture on December 12, 1946 The Preparation of Pure Enzymes and Virus Proteins
February 16, 2024
john, howard, northrop, this, article, about, nobel, laureate, chemist, other, uses, john, northrop, july, 1891, 1987, american, biochemist, with, james, batcheller, sumner, wendell, meredith, stanley, 1946, nobel, prize, chemistry, award, given, these, scient. This article is about the Nobel Laureate chemist For other uses see John Northrop John Howard Northrop July 5 1891 May 27 1987 was an American biochemist who with James Batcheller Sumner and Wendell Meredith Stanley won the 1946 Nobel Prize in Chemistry The award was given for these scientists isolation crystallization and study of enzymes proteins and viruses 1 Northrop was a Professor of Bacteriology and Medical Physics Emeritus at University of California Berkeley 2 John Howard NorthropBorn 1891 07 05 July 5 1891Yonkers New York U S DiedMay 27 1987 1987 05 27 aged 95 Wickenburg Arizona U S Alma materColumbia UniversityKnown forStudies of enzymesAwardsNobel Prize in Chemistry 1946 Daniel Giraud Elliot Medal 1939 Scientific careerFieldsBiochemistryInstitutionsUniversity of California BerkeleyColumbia UniversityRockefeller University Contents 1 Biography 1 1 Early years 1 2 Research 1 3 Personal life 2 References 3 Further reading 4 External linksBiography editEarly years edit Northrop was born in Yonkers New York to John Isaiah a zoologist and instructor at Columbia University who is a member of the Havemeyer family and Alice Rich Northrop a teacher of botany at Hunter College His father died in a lab explosion two weeks before John H Northrop was born The son was educated at Yonkers High School and Columbia University where he earned his BA in 1912 and PhD in chemistry in 1915 3 4 During World War I he conducted research for the U S Chemical Warfare Service on the production of acetone and ethanol through fermentation This work led to studying enzymes Research edit In 1929 Northrop isolated and crystallized the gastric enzyme pepsin 5 and determined that it was a protein For this achievement he was elected to the United States National Academy of Sciences in 1934 6 In 1938 he isolated and crystallized the first bacteriophage a small virus that attacks bacteria and determined that it was a nucleoprotein He was elected to the American Philosophical Society that same year 7 Northrop also isolated and crystallized pepsinogen the precursor to pepsin trypsin chymotrypsin and carboxypeptidase For his 1939 book Crystalline Enzymes The Chemistry of Pepsin Trypsin and Bacteriophage Northrop was awarded the Daniel Giraud Elliot Medal from the National Academy of Sciences 8 He was elected a Fellow of the American Academy of Arts and Sciences in 1949 9 Northrop was employed by the Rockefeller Institute for Medical Research in New York City from 1916 until his retirement in 1961 In 1949 he joined the University of California Berkeley as Professor of Bacteriology and later he was appointed Professor of Biophysics 10 Personal life edit In 1917 Northrop married Louise Walker 1891 1975 with whom he had two children John an oceanographer and Alice who married Nobel laureate Frederick C Robbins The family lived in a small home just outside of Mt Vernon New York As their children grew older and Northrop looked for a more desirable workplace the family bought a home in Cotuit Massachusetts This move shortened Northrop s commute to the laboratory in Princeton New Jersey and also put him in closer contact with the wilderness which he greatly enjoyed 11 Northrop committed suicide in Wickenburg Arizona in 1987 12 References edit The Nobel Prize in Chemistry 1946 Preparing Pure Proteins Retrieved December 14 2008 University of California In Memoriam 1988 Alexander Hamilton Medal Columbia College Alumni Association December 14 2016 Retrieved June 24 2022 Columbia College Columbia University Office of Alumni Affairs and Development Columbia College Columbia University 1960 1961 Columbia College today Columbia University Libraries New York N Y Columbia College Office of Alumni Affairs and Development Northrop J H 1929 Crystalline Pepsin Science 69 1796 580 Bibcode 1929Sci 69 580N doi 10 1126 science 69 1796 580 PMID 17758437 John H Northrop www nasonline org Retrieved May 19 2023 APS Member History search amphilsoc org Retrieved May 19 2023 Daniel Giraud Elliot Medal National Academy of Sciences Archived from the original on December 29 2010 Retrieved February 16 2011 Book of Members 1780 2010 Chapter N PDF American Academy of Arts and Sciences Retrieved April 15 2011 John H Northrop Biographical Nobel Foundation Retrieved April 29 2017 Biographical Memoirs 1994 doi 10 17226 4560 ISBN 978 0 309 04976 4 See p 440 of Herriott R M 1994 John Howard Northrop July 5 1891 May 27 1987 Biographical Memoirs National Academy of Sciences U S vol 63 pp 423 450 PMID 11615389Further reading editEconomos A C Lints F A 1985 Growth rate and life span in Drosophila V The effect of prolongation of the period of growth on the total duration of life J H Northrop 1917 revisited Mech Ageing Dev published December 1985 vol 33 no 1 pp 103 113 doi 10 1016 0047 6374 85 90112 5 PMID 3908838 S2CID 23576391 Herriott R M 1981 John Howard Northrop J Gen Physiol published June 1981 vol 77 no 6 pp 597 599 doi 10 1085 jgp 77 6 597 PMC 2215443 PMID 7021760 Herriott R M 1994 John Howard Northrop July 5 1891 May 27 1987 Biographical Memoirs National Academy of Sciences U S vol 63 pp 423 450 PMID 11615389See also this version of Northrop s National Academy of Science biography Northrop J H 1939 Crystalline Enzymes Columbia University Press Shampo M A Kyle R A 2000 John Northrop definitive study of enzymes Mayo Clin Proc published March 2000 vol 75 no 3 p 254 doi 10 4065 75 3 254 PMID 10725951 van Helvoort T 1992 The controversy between John H Northrop and Max Delbruck on the formation of bacteriophage bacterial synthesis or autonomous multiplication Annals of Science published November 1992 vol 49 no 6 pp 545 575 doi 10 1080 00033799200200451 PMID 11616207External links editWorks by or about John Howard Northrop at Internet Archive John Howard Northrop on Nobelprize org nbsp including the Nobel Lecture on December 12 1946 The Preparation of Pure Enzymes and Virus Proteins Retrieved from https en wikipedia org w index php title John Howard Northrop amp oldid 1171455713, wikipedia, wiki, book, books, library,
