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Wikipedia

IFIT1

January 01, 1970

Interferon-induced protein with tetratricopeptide repeats 1 is a protein that in humans is encoded by the IFIT1 gene.[4][5][6]

IFIT1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIFIT1, C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561, interferon induced protein with tetratricopeptide repeats 1
External IDsOMIM: 147690; MGI: 2148249; HomoloGene: 78213; GeneCards: IFIT1; OMA:IFIT1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

3434

112419

Ensembl

n/a

ENSMUSG00000067297

UniProt

P09914

Q3U687

RefSeq (mRNA)

NM_001548
NM_001270927
NM_001270928
NM_001270929
NM_001270930

NM_053217
NM_001362130

RefSeq (protein)

NP_001257856
NP_001257857
NP_001257858
NP_001257859
NP_001539

NP_444447
NP_001349059

Location (UCSC)n/aChr 19: 34.59 – 34.62 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

References edit

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067297 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Lafage M, Clauss I, Couez D, Simonetti J, Wathelet MG, Huez G (Jul 1992). "The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24". Genomics. 13 (2): 458–60. doi:10.1016/0888-7543(92)90272-T. PMID 1377167.
  5. ^ Wathelet MG, Clauss IM, Content J, Huez GA (Jun 1988). "The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family". FEBS Lett. 231 (1): 164–71. doi:10.1016/0014-5793(88)80724-5. PMID 3360121. S2CID 22937671.
  6. ^ "Entrez Gene: IFIT1 interferon-induced protein with tetratricopeptide repeats 1".

Further reading edit

  • Wathelet MG, Clauss IM, Nols CB, et al. (1988). "New inducers revealed by the promoter sequence analysis of two interferon-activated human genes". Eur. J. Biochem. 169 (2): 313–21. doi:10.1111/j.1432-1033.1987.tb13614.x. PMID 3121313.
  • Wathelet MG, Szpirer J, Nols CB, et al. (1988). "Cloning and chromosomal location of human genes inducible by type I interferon". Somat. Cell Mol. Genet. 14 (5): 415–26. doi:10.1007/BF01534709. PMID 3175763. S2CID 42406993.
  • Kusari J, Szabo P, Grzeschik KH, Sen GC (1987). "Chromosomal localization of the interferon-inducible human gene encoding mRNA 561". J. Interferon Res. 7 (1): 53–9. doi:10.1089/jir.1987.7.53. PMID 3585080.
  • Wathelet M, Moutschen S, Defilippi P, et al. (1986). "Molecular cloning, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons". Eur. J. Biochem. 155 (1): 11–7. doi:10.1111/j.1432-1033.1986.tb09452.x. PMID 3753936.
  • Chebath J, Merlin G, Metz R, et al. (1983). "Interferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA". Nucleic Acids Res. 11 (5): 1213–26. doi:10.1093/nar/11.5.1213. PMC 325791. PMID 6186990.
  • Rebouillat D, Marié I, Hovanessian AG (1998). "Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase". Eur. J. Biochem. 257 (2): 319–30. doi:10.1046/j.1432-1327.1998.2570319.x. PMID 9826176.
  • Guo J, Sen GC (2000). "Characterization of the Interaction between the Interferon-Induced Protein P56 and the Int6 Protein Encoded by a Locus of Insertion of the Mouse Mammary Tumor Virus". J. Virol. 74 (4): 1892–9. doi:10.1128/JVI.74.4.1892-1899.2000. PMC 111667. PMID 10644362.
  • Guo J, Peters KL, Sen GC (2000). "Induction of the human protein P56 by interferon, double-stranded RNA, or virus infection". Virology. 267 (2): 209–19. doi:10.1006/viro.1999.0135. PMID 10662616.
  • Guo J, Hui DJ, Merrick WC, Sen GC (2001). "A new pathway of translational regulation mediated by eukaryotic initiation factor 3". EMBO J. 19 (24): 6891–9. doi:10.1093/emboj/19.24.6891. PMC 305884. PMID 11118224.
  • Patzwahl R, Meier V, Ramadori G, Mihm S (2001). "Enhanced Expression of Interferon-Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection: Detection by Suppression-Subtractive Hybridization". J. Virol. 75 (3): 1332–8. doi:10.1128/JVI.75.3.1332-1338.2001. PMC 114039. PMID 11152506.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gavrilov BG, Monastyrskaia GS, Velikodvorskaia TV, et al. (2003). "[Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus]". Bioorg. Khim. 29 (2): 175–80. doi:10.1023/a:1023260415910. PMID 12708317. S2CID 34300356.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Terenzi F, Hui DJ, Merrick WC, Sen GC (2006). "Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56". J. Biol. Chem. 281 (45): 34064–71. doi:10.1074/jbc.M605771200. PMID 16973618.


 

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.

January 01, 1970
ifit1, interferon, induced, protein, with, tetratricopeptide, repeats, protein, that, humans, encoded, gene, available, structurespdbortholog, search, pdbe, rcsblist, codes4houidentifiersaliases, g10p1, ifi56, ifit, ifnai1, isg56, rnm561, interferon, induced, . Interferon induced protein with tetratricopeptide repeats 1 is a protein that in humans is encoded by the IFIT1 gene 4 5 6 IFIT1Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes4HOUIdentifiersAliasesIFIT1 C56 G10P1 IFI 56 IFI 56K IFI56 IFIT 1 IFNAI1 ISG56 P56 RNM561 interferon induced protein with tetratricopeptide repeats 1External IDsOMIM 147690 MGI 2148249 HomoloGene 78213 GeneCards IFIT1 OMA IFIT1 orthologsGene location Mouse Chr Chromosome 19 mouse 1 Band19 19 C1Start34 594 449 bp 1 End34 618 143 bp 1 RNA expression patternBgeeHumanMouse ortholog Top expressed inponstrigeminal ganglionbiceps brachiiglomerulusmetanephric glomeruluspalpebral conjunctivasubthalamic nucleusgerminal epitheliumamniotic fluidparietal pleuraTop expressed injejunumsecondary oocyteileuminterventricular septumduodenumcolonPaneth cellsexually immature organismleft colonbloodMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionprotein binding RNA bindingCellular componentcytoplasm host cell cytosolBiological processnegative regulation of helicase activity response to virus positive regulation of viral genome replication negative regulation of viral genome replication negative regulation of defense response to virus by host cellular response to type I interferon viral process intracellular transport of viral protein in host cell negative regulation of protein binding type I interferon signaling pathway innate immune response regulation of defense response to virus cellular response to exogenous dsRNA immune system process defense response to virus response to bacterium cellular response to interferon betaSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez3434112419Ensembln aENSMUSG00000067297UniProtP09914Q3U687RefSeq mRNA NM 001548NM 001270927NM 001270928NM 001270929NM 001270930NM 053217NM 001362130RefSeq protein NP 001257856NP 001257857NP 001257858NP 001257859NP 001539NP 444447NP 001349059Location UCSC n aChr 19 34 59 34 62 MbPubMed search 2 3 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCm38 Ensembl release 89 ENSMUSG00000067297 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Lafage M Clauss I Couez D Simonetti J Wathelet MG Huez G Jul 1992 The interferon and virus inducible IFI 56K and IFI 54K genes are located on human chromosome 10 at bands q23 q24 Genomics 13 2 458 60 doi 10 1016 0888 7543 92 90272 T PMID 1377167 Wathelet MG Clauss IM Content J Huez GA Jun 1988 The IFI 56K and IFI 54K interferon inducible human genes belong to the same gene family FEBS Lett 231 1 164 71 doi 10 1016 0014 5793 88 80724 5 PMID 3360121 S2CID 22937671 Entrez Gene IFIT1 interferon induced protein with tetratricopeptide repeats 1 Further reading editWathelet MG Clauss IM Nols CB et al 1988 New inducers revealed by the promoter sequence analysis of two interferon activated human genes Eur J Biochem 169 2 313 21 doi 10 1111 j 1432 1033 1987 tb13614 x PMID 3121313 Wathelet MG Szpirer J Nols CB et al 1988 Cloning and chromosomal location of human genes inducible by type I interferon Somat Cell Mol Genet 14 5 415 26 doi 10 1007 BF01534709 PMID 3175763 S2CID 42406993 Kusari J Szabo P Grzeschik KH Sen GC 1987 Chromosomal localization of the interferon inducible human gene encoding mRNA 561 J Interferon Res 7 1 53 9 doi 10 1089 jir 1987 7 53 PMID 3585080 Wathelet M Moutschen S Defilippi P et al 1986 Molecular cloning full length sequence and preliminary characterization of a 56 kDa protein induced by human interferons Eur J Biochem 155 1 11 7 doi 10 1111 j 1432 1033 1986 tb09452 x PMID 3753936 Chebath J Merlin G Metz R et al 1983 Interferon induced 56 000 Mr protein and its mRNA in human cells molecular cloning and partial sequence of the cDNA Nucleic Acids Res 11 5 1213 26 doi 10 1093 nar 11 5 1213 PMC 325791 PMID 6186990 Rebouillat D Marie I Hovanessian AG 1998 Molecular cloning and characterization of two related and interferon induced 56 kDa and 30 kDa proteins highly similar to 2 5 oligoadenylate synthetase Eur J Biochem 257 2 319 30 doi 10 1046 j 1432 1327 1998 2570319 x PMID 9826176 Guo J Sen GC 2000 Characterization of the Interaction between the Interferon Induced Protein P56 and the Int6 Protein Encoded by a Locus of Insertion of the Mouse Mammary Tumor Virus J Virol 74 4 1892 9 doi 10 1128 JVI 74 4 1892 1899 2000 PMC 111667 PMID 10644362 Guo J Peters KL Sen GC 2000 Induction of the human protein P56 by interferon double stranded RNA or virus infection Virology 267 2 209 19 doi 10 1006 viro 1999 0135 PMID 10662616 Guo J Hui DJ Merrick WC Sen GC 2001 A new pathway of translational regulation mediated by eukaryotic initiation factor 3 EMBO J 19 24 6891 9 doi 10 1093 emboj 19 24 6891 PMC 305884 PMID 11118224 Patzwahl R Meier V Ramadori G Mihm S 2001 Enhanced Expression of Interferon Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection Detection by Suppression Subtractive Hybridization J Virol 75 3 1332 8 doi 10 1128 JVI 75 3 1332 1338 2001 PMC 114039 PMID 11152506 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Gavrilov BG Monastyrskaia GS Velikodvorskaia TV et al 2003 Late activation of interferon induced genes IFI 54k and IFI 56k in human RH cells infected with tick borne encephalitis virus Bioorg Khim 29 2 175 80 doi 10 1023 a 1023260415910 PMID 12708317 S2CID 34300356 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Gerhard DS Wagner L Feingold EA et al 2004 The Status Quality and Expansion of the NIH Full Length cDNA Project The Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Rual JF Venkatesan K Hao T et al 2005 Towards a proteome scale map of the human protein protein interaction network Nature 437 7062 1173 8 Bibcode 2005Natur 437 1173R doi 10 1038 nature04209 PMID 16189514 S2CID 4427026 Kimura K Wakamatsu A Suzuki Y et al 2006 Diversification of transcriptional modulation Large scale identification and characterization of putative alternative promoters of human genes Genome Res 16 1 55 65 doi 10 1101 gr 4039406 PMC 1356129 PMID 16344560 Terenzi F Hui DJ Merrick WC Sen GC 2006 Distinct induction patterns and functions of two closely related interferon inducible human genes ISG54 and ISG56 J Biol Chem 281 45 34064 71 doi 10 1074 jbc M605771200 PMID 16973618 nbsp This article on a gene on human chromosome 10 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title IFIT1 amp oldid 1142678750, 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