From the Fall of 1973 until 1977, Fox was a research associate with Carl R. Woese at the University of Illinois at Urbana-Champaign. Their collaboration initially focused on 5S ribosomal RNA where they established the use of a comparative sequence approach to predict RNA secondary structure.[1] Next, utilizing 16S ribosomal RNA finger printing technology developed in the Woese laboratory in large part by Mitchell Sogin, Fox and Woese discovered the third form of life now known as the Archaea.[2]
It has been said that their 1977 paper “may be the most important paper ever in microbiology”.[3] This seminal paper is now considered to be a PNAS classic.[4] Fox and Woese also introduced the idea of a progenote as a primordial entity in the evolution of life.[5]
In the Fall of 1977, Fox moved on to the University of Houston and as a new Assistant Professor in Biochemical & Biophysical Sciences, continued to collaborate with Woese. This resulted in the 1980 publication of the “big tree”, the first comprehensive tree of bacterial relationships.[6][7] Fox also recognized the limitations that 16S rRNA sequences could provide when identifying closely related species and addressed the question of “How Close is Close?".[8]
He became a full professor there in 1986. His current research centers around understanding the early evolution of life with particular interest in the origin and evolution of the ribosome.[9][10] He has also assisted NASA scientists on multiple occasions in characterizing relevant microbial communities.[11]
Three-domain system Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya
Books describing discovery of Archaeaedit
1. Quammen , D.(2018).“The Tangled Tree: A Radical New History of Life.” Simon & Schuster ISBN978-1-4767-7662-0. 2. Sapp, J. (2009).“The New Foundations of Evolution,” Oxford University Press,ISBN9780195388503.
^Woese CR, Fox GE (November 1977). "Phylogenetic structure of the prokaryotic domain: the primary kingdoms". Proceedings of the National Academy of Sciences of the United States of America. 74 (11): 5088–5090. Bibcode:1977PNAS...74.5088W. doi:10.1073/pnas.74.11.5088. PMC432104. PMID 2112744.
^"Most important paper ever in microbiology? Woese & Fox, 1977, discovery of archaea". Jonathan Eisen's Lab. 6 April 2010.
^Woese CR, Fox GE (September 1977). "The concept of cellular evolution". J. Mol. Evol. 10 (1): 1–6. Bibcode:1977JMolE..10....1W. doi:10.1007/BF01796132. PMID 903983. S2CID 24613906.
^Woese CR, Magrum L, Fox GE (August 1978). "Archaebacteria". J. Mol. Evol. 11 (3): 245–251. Bibcode:1978JMolE..11..245W. doi:10.1007/BF01734485. PMID 681075.
^Fox GE, Wisotzkey J, Jurtshuk P (January 1992). "How close in close:16S rRNA sequence identity may not be sufficient to guarantee species identity". Int. J. Syst. Bacteriol. 42 (1): 166–170. doi:10.1099/00207713-42-1-166. PMID 1371061.
^Fox GE (June 2010). "Origin and evolution of the ribosome". Cold Spring Harb Perspect Biol. 2 (9:a003483): a003483. doi:10.1101/cshperspect.a003483. PMC2926754. PMID 20534711.
^Nair P (2012). "Woese and Fox: Life, rearranged". Proceedings of the National Academy of Sciences of the United States of America. 109 (4): 1019–1021. doi:10.1073/pnas.1120749109. PMC3268309. PMID 22308527.
^Sielaff AC, Urbaniak C, Mohan GB, Stepanov VG, Tran Q, Wood JM, Minich J, McDonald D, Mayer T, Knight R, Karouia, Fox GE, Venkateswaran K (April 2019). "Characterization of the total and viable bacterial and fungal communities associated with the International Space Station surfaces". Microbiome. 7 (1): 50. doi:10.1186/s40168-019-0666-x. PMC6452512. PMID 30955503. S2CID 102349152.
[6] Fellow in the International Society for the Study of the Origin of Life (ISSOL)
Four Pioneering Scientists to Discuss “The Origins of the RNA World”
[8] The Library of Congress Astrobiology Chair Nathaniel Comfort Discusses the RNA World with Pioneering Scientists
Most important paper ever in microbiology? Woese & Fox, 1977, Discovery of Archaea
[10] Details of Ribosome Structure, Function and History Aaron Gronstal, 2020, NASA Astrobiology Exobiology Program, Center for the Origin of Life (COOL)
February 15, 2024
george, other, people, named, george, george, disambiguation, george, edward, born, december, 1945, astrobiologist, professor, emeritus, researcher, university, houston, elected, fellow, american, academy, microbiology, american, association, advancement, scie. For other people named George Fox see George Fox disambiguation George Edward Fox born December 17 1945 is an astrobiologist a Professor Emeritus and researcher at the University of Houston He is an elected fellow of the American Academy of Microbiology the American Association for the Advancement of Science American Institute for Medical and Biological Engineering and the International Astrobiology Society Fox received his B A degree in 1967 and completed his Ph D degree in 1974 both in chemical engineering at Syracuse University George E FoxFox at the John W Kluge Center at the Library of Congress in 2016Born 1945 12 17 December 17 1945 age 78 United StatesNationalityAmericanAlma materSyracuse UniversityScientific careerFieldsBiologyInstitutionsUniversity of HoustonFrom the Fall of 1973 until 1977 Fox was a research associate with Carl R Woese at the University of Illinois at Urbana Champaign Their collaboration initially focused on 5S ribosomal RNA where they established the use of a comparative sequence approach to predict RNA secondary structure 1 Next utilizing 16S ribosomal RNA finger printing technology developed in the Woese laboratory in large part by Mitchell Sogin Fox and Woese discovered the third form of life now known as the Archaea 2 It has been said that their 1977 paper may be the most important paper ever in microbiology 3 This seminal paper is now considered to be a PNAS classic 4 Fox and Woese also introduced the idea of a progenote as a primordial entity in the evolution of life 5 In the Fall of 1977 Fox moved on to the University of Houston and as a new Assistant Professor in Biochemical amp Biophysical Sciences continued to collaborate with Woese This resulted in the 1980 publication of the big tree the first comprehensive tree of bacterial relationships 6 7 Fox also recognized the limitations that 16S rRNA sequences could provide when identifying closely related species and addressed the question of How Close is Close 8 He became a full professor there in 1986 His current research centers around understanding the early evolution of life with particular interest in the origin and evolution of the ribosome 9 10 He has also assisted NASA scientists on multiple occasions in characterizing relevant microbial communities 11 Contents 1 See also 2 Books describing discovery of Archaea 3 References 4 External linksSee also editThree domain system Towards a natural system of organisms proposal for the domains Archaea Bacteria and EucaryaBooks describing discovery of Archaea edit1 Quammen D 2018 The Tangled Tree A Radical New History of Life Simon amp Schuster ISBN 978 1 4767 7662 0 2 Sapp J 2009 The New Foundations of Evolution Oxford University Press ISBN 9780195388503 References edit Fox GE Woese CR August 1975 5S rRNA Secondary Structure Nature 256 5517 505 507 Bibcode 1975Natur 256 505F doi 10 1038 256505a0 PMID 808733 S2CID 4288247 Woese CR Fox GE November 1977 Phylogenetic structure of the prokaryotic domain the primary kingdoms Proceedings of the National Academy of Sciences of the United States of America 74 11 5088 5090 Bibcode 1977PNAS 74 5088W doi 10 1073 pnas 74 11 5088 PMC 432104 PMID 2112744 Most important paper ever in microbiology Woese amp Fox 1977 discovery of archaea Jonathan Eisen s Lab 6 April 2010 PNAS Classics PNAS Woese CR Fox GE September 1977 The concept of cellular evolution J Mol Evol 10 1 1 6 Bibcode 1977JMolE 10 1W doi 10 1007 BF01796132 PMID 903983 S2CID 24613906 Woese CR Magrum L Fox GE August 1978 Archaebacteria J Mol Evol 11 3 245 251 Bibcode 1978JMolE 11 245W doi 10 1007 BF01734485 PMID 681075 Fox GE Stackebrandt Hespel RB Gibson J Maniloff J Dyer TA Wolfe RS Balch WE Tanner RS Magrum LJ Zablen LB Blakemore R Gupta R Bonen L Lewis BJ Stahl DA Luehrsen KR Chen KN Woese CR July 1980 The phylogeny of procaryotes Science 209 4455 457 463 Bibcode 1980Sci 209 457F doi 10 1126 science 6771870 PMID 6771870 Fox GE Wisotzkey J Jurtshuk P January 1992 How close in close 16S rRNA sequence identity may not be sufficient to guarantee species identity Int J Syst Bacteriol 42 1 166 170 doi 10 1099 00207713 42 1 166 PMID 1371061 Fox GE June 2010 Origin and evolution of the ribosome Cold Spring Harb Perspect Biol 2 9 a003483 a003483 doi 10 1101 cshperspect a003483 PMC 2926754 PMID 20534711 Nair P 2012 Woese and Fox Life rearranged Proceedings of the National Academy of Sciences of the United States of America 109 4 1019 1021 doi 10 1073 pnas 1120749109 PMC 3268309 PMID 22308527 Sielaff AC Urbaniak C Mohan GB Stepanov VG Tran Q Wood JM Minich J McDonald D Mayer T Knight R Karouia Fox GE Venkateswaran K April 2019 Characterization of the total and viable bacterial and fungal communities associated with the International Space Station surfaces Microbiome 7 1 50 doi 10 1186 s40168 019 0666 x PMC 6452512 PMID 30955503 S2CID 102349152 External links editSearch Results for author Fox George E on PubMed 1 Google Scholar Profile 2 Google Scholar 3 at the University of Houston Houston Texas 4 BBC News 5 The Space Show Broadcast 6 Fellow in the International Society for the Study of the Origin of Life ISSOL 7 Four Pioneering Scientists to Discuss The Origins of the RNA World 8 The Library of Congress Astrobiology Chair Nathaniel Comfort Discusses the RNA World with Pioneering Scientists 9 Most important paper ever in microbiology Woese amp Fox 1977 Discovery of Archaea 10 Details of Ribosome Structure Function and History Aaron Gronstal 2020 NASA Astrobiology Exobiology Program Center for the Origin of Life COOL Retrieved from https en wikipedia org w index php title George E Fox amp oldid 1188163073, wikipedia, wiki, book, books, library,
