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Wikipedia

Butirosin

Butirosin is an aminoglycoside antibiotic complex which is active against both Gram-positive and Gram-negative bacteria.[1] It is a mixture with butirosin A (80-85%) and butirosin B being the major components.[2]

Butirosin
INN: Butirosin
Butirosin A (top) and butirosin B (bottom)
Clinical data
Other namesAmbutyrosin; Butyrosin
Drug classAminoglycoside antibiotic
Identifiers
CAS Number
  • 12772-35-9 Y
PubChem CID
  • 72393
ChemSpider
  • 65326
UNII
  • 8S52KR0L58
KEGG
  • C01559
ChEBI
  • CHEBI:65109
CompTox Dashboard (EPA)
  • DTXSID60925967
Chemical and physical data
3D model (JSmol)
  • Interactive image
  • C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@@H](CCN)O)O)O[C@@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N
  • InChI=1S/C21H41N5O12/c22-2-1-8(28)19(34)26-7-3-6(24)17(37-20-11(25)15(32)13(30)9(4-23)35-20)18(12(7)29)38-21-16(33)14(31)10(5-27)36-21/h6-18,20-21,27-33H,1-5,22-25H2,(H,26,34)/t6-,7+,8+,9+,10+,11+,12-,13+,14+,15+,16+,17+,18+,20+,21+/m0/s1
  • Key:XEQLFNPSYWZPOW-NUOYRARPSA-N

References edit

  1. ^ Heifetz CL, Fisher MW, Chodubski JA, DeCarlo MO (August 1972). "Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice". Antimicrobial Agents and Chemotherapy. 2 (2): 89–94. doi:10.1128/aac.2.2.89. PMC 444273. PMID 4670492.
  2. ^ Elks J (2014). The Dictionary of Drugs. Springer. p. 198.

butirosin, aminoglycoside, antibiotic, complex, which, active, against, both, gram, positive, gram, negative, bacteria, mixture, with, butirosin, butirosin, being, major, components, butirosin, bottom, clinical, dataother, namesambutyrosin, butyrosindrug, clas. Butirosin is an aminoglycoside antibiotic complex which is active against both Gram positive and Gram negative bacteria 1 It is a mixture with butirosin A 80 85 and butirosin B being the major components 2 ButirosinINN ButirosinButirosin A top and butirosin B bottom Clinical dataOther namesAmbutyrosin ButyrosinDrug classAminoglycoside antibioticIdentifiersCAS Number12772 35 9 YPubChem CID72393ChemSpider65326UNII8S52KR0L58KEGGC01559ChEBICHEBI 65109CompTox Dashboard EPA DTXSID60925967Chemical and physical data3D model JSmol Interactive imageSMILES C1 C H C H C H C H C H 1NC O C H CCN O O O C H 2 C H C H C H O2 CO O O O C H 3 C H C H C H C H O3 CN O O N NInChI InChI 1S C21H41N5O12 c22 2 1 8 28 19 34 26 7 3 6 24 17 37 20 11 25 15 32 13 30 9 4 23 35 20 18 12 7 29 38 21 16 33 14 31 10 5 27 36 21 h6 18 20 21 27 33H 1 5 22 25H2 H 26 34 t6 7 8 9 10 11 12 13 14 15 16 17 18 20 21 m0 s1Key XEQLFNPSYWZPOW NUOYRARPSA NReferences edit Heifetz CL Fisher MW Chodubski JA DeCarlo MO August 1972 Butirosin a new aminoglycosidic antibiotic complex antibacterial activity in vitro and in mice Antimicrobial Agents and Chemotherapy 2 2 89 94 doi 10 1128 aac 2 2 89 PMC 444273 PMID 4670492 Elks J 2014 The Dictionary of Drugs Springer p 198 nbsp This antiinfective drug article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Butirosin amp oldid 1137944995, wikipedia, wiki, book, books, library,

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