The Baggio–Yoshinari syndrome , formerly known as the Brazilian Lyme-like disease and Brazilian human borreliosis, is a disease transmitted by the Amblyomma cajennense tick, but the organism that causes the infection is still unknown.[1] Clinical features resemble those of Lyme disease (LD).[2]
A distinct feature of the syndrome is its prolonged clinical evolution, with relapsing episodes and autoimmune dysfunction. If diagnosed in its early stages, the symptoms respond well to antibiotics. If the disease evolves to a chronic phase, it can potentially cause oligoarthritis, cognitive impairment, meningoencephalitis and erythema nodosum, with the patient risking to develop both articular and neurological sequelae.[2]
Likely transmission vectors of BYS belong to the Amblyomma and Rhipicephalus genera, which could help to explain all the particularities observed in BYS versus LD.[1]
Some features of BYS also resemble those found in the Southern tick-associated rash illness (STARI, also known as Masters' disease), which is found in the Southern USA.[1]
Diagnosisedit
This section is empty. You can help by adding to it. (March 2018)
Historyedit
In 1989, Brazilian researchers Professors Domingos Baggio (an entomologist from the Biomedical Sciences Institute of the University of São Paulo), Paulo Yasuda (a microbiologist from the same institute) and Natalino Hajime Yoshinari (a physician from the Rheumatology Department at University of São Paulo's Medical School[1]) started research on Lyme disease in Brazil, by suggestion of Dr. Allen Steere. At that time, LD was almost unknown among Brazilian physicians.[3]
The first cases were described in Brazil in 1992 in siblings from Cotia, São Paulo that developed symptoms as a migrating redness, general flu-like symptoms and arthritis after being bitten by ticks. Although the symptoms were similar to those presented by patients of Lyme disease, clinical and laboratorial results were considerably different. Ticks of the Ixodes ricinuscomplex were not found at the risk areas; bacteria from the Borrelia burgdorferisensu lato complex —that cause Lyme disease— were not found in biological fluids and tissues of the siblings.[4] Blood analysis of the patients on electron microscopy exhibited structures resembling microorganisms of the spirochaetephylum. For these reasons, the Brazilian zoonosis was considered a new disease and named Baggio–Yoshinari Syndrome (BYS), defined as: "Exotic and emerging Brazilian infectious disease, transmitted by ticks not belonging to the Ixodes ricinus complex, caused by latent spirochetes with atypical morphology, which originates LD-like symptoms, except for occurrence of relapsing episodes and auto-immune disorders".[4]
Referencesedit
^ abcdeRevista Brasileira de Reumatologia, vol.49 no.5, São Paulo, Sept./Oct. 2009: Neurological manifestations in Baggio-Yoshinari Syndrome (Brazilian Lyme-like disease syndrome)
^ abRevista Brasileira de Reumatologia, Vol.54, Issue 2, March–April 2014, Pages 148–151. Chronic lymphomonocytic meningoencephalitis, oligoarthritis and erythema nodosum: report of Baggio-Yoshinari syndrome of long and relapsing evolution
^Revista Brasileira de Pesquisas Médicas e Biológicas vol.40 no.4 Ribeirão Preto Apr. 2007: Description of Lyme disease-like syndrome in Brazil. Is it a new tick borne disease or Lyme disease variation?
^ abRevista da Associação Médica Brasileira vol.56 no.3 São Paulo, 2010: Brazilian Lyme-like disease or Baggio-Yoshinari syndrome: exotic and emerging Brazilian tick-borne zoonosis
December 18, 2023
baggio, yoshinari, syndrome, formerly, known, brazilian, lyme, like, disease, brazilian, human, borreliosis, disease, transmitted, amblyomma, cajennense, tick, organism, that, causes, infection, still, unknown, clinical, features, resemble, those, lyme, diseas. The Baggio Yoshinari syndrome formerly known as the Brazilian Lyme like disease and Brazilian human borreliosis is a disease transmitted by the Amblyomma cajennense tick but the organism that causes the infection is still unknown 1 Clinical features resemble those of Lyme disease LD 2 Baggio Yoshinari syndromeOther namesBYSAmblyomma cajennense transmits the conditionSpecialtyInfectious disease Contents 1 Presentation 2 Diagnosis 3 History 4 ReferencesPresentation editA distinct feature of the syndrome is its prolonged clinical evolution with relapsing episodes and autoimmune dysfunction If diagnosed in its early stages the symptoms respond well to antibiotics If the disease evolves to a chronic phase it can potentially cause oligoarthritis cognitive impairment meningoencephalitis and erythema nodosum with the patient risking to develop both articular and neurological sequelae 2 The neurological manifestations of BYS were first described by Yoshinari et al including patients with peripheral neuritis meningitis and cranial neuritis facial nerve palsy diplopia and deafness 1 Likely transmission vectors of BYS belong to the Amblyomma and Rhipicephalus genera which could help to explain all the particularities observed in BYS versus LD 1 Some features of BYS also resemble those found in the Southern tick associated rash illness STARI also known as Masters disease which is found in the Southern USA 1 Diagnosis editThis section is empty You can help by adding to it March 2018 History editIn 1989 Brazilian researchers Professors Domingos Baggio an entomologist from the Biomedical Sciences Institute of the University of Sao Paulo Paulo Yasuda a microbiologist from the same institute and Natalino Hajime Yoshinari a physician from the Rheumatology Department at University of Sao Paulo s Medical School 1 started research on Lyme disease in Brazil by suggestion of Dr Allen Steere At that time LD was almost unknown among Brazilian physicians 3 The first cases were described in Brazil in 1992 in siblings from Cotia Sao Paulo that developed symptoms as a migrating redness general flu like symptoms and arthritis after being bitten by ticks Although the symptoms were similar to those presented by patients of Lyme disease clinical and laboratorial results were considerably different Ticks of the Ixodes ricinus complex were not found at the risk areas bacteria from the Borrelia burgdorferi sensu lato complex that cause Lyme disease were not found in biological fluids and tissues of the siblings 4 Blood analysis of the patients on electron microscopy exhibited structures resembling microorganisms of the spirochaete phylum For these reasons the Brazilian zoonosis was considered a new disease and named Baggio Yoshinari Syndrome BYS defined as Exotic and emerging Brazilian infectious disease transmitted by ticks not belonging to the Ixodes ricinus complex caused by latent spirochetes with atypical morphology which originates LD like symptoms except for occurrence of relapsing episodes and auto immune disorders 4 References edit a b c d e Revista Brasileira de Reumatologia vol 49 no 5 Sao Paulo Sept Oct 2009 Neurological manifestations in Baggio Yoshinari Syndrome Brazilian Lyme like disease syndrome a b Revista Brasileira de Reumatologia Vol 54 Issue 2 March April 2014 Pages 148 151 Chronic lymphomonocytic meningoencephalitis oligoarthritis and erythema nodosum report of Baggio Yoshinari syndrome of long and relapsing evolution Revista Brasileira de Pesquisas Medicas e Biologicas vol 40 no 4 Ribeirao Preto Apr 2007 Description of Lyme disease like syndrome in Brazil Is it a new tick borne disease or Lyme disease variation a b Revista da Associacao Medica Brasileira vol 56 no 3 Sao Paulo 2010 Brazilian Lyme like disease or Baggio Yoshinari syndrome exotic and emerging Brazilian tick borne zoonosis Retrieved from https en wikipedia org w index php title Baggio Yoshinari syndrome amp oldid 1088913846, wikipedia, wiki, book, books, library,
