Auditory processing disorder

Auditory processing disorder (APD), rarely known as King-Kopetzky syndrome or auditory disability with normal hearing (ADN), is a neurodevelopmental disorder affecting the way the brain processes sounds.^[2] Individuals with APD usually have normal structure and function of the outer, middle, and inner ear (peripheral hearing). However, they cannot process the information they hear in the same way as others do, which leads to difficulties in recognizing and interpreting sounds, especially the sounds composing speech. It is thought that these difficulties arise from dysfunction in the central nervous system.^[3]

Auditory processing disorder
Other names	Central auditory processing disorder
Specialty	Audiology, neurology^[1]

The American Academy of Audiology notes that APD is diagnosed by difficulties in one or more auditory processes known to reflect the function of the central auditory nervous system.^[2] It can affect both children and adults. Although the actual prevalence is currently unknown, it has been estimated to impact 2–7% in children in US and UK populations.^[4] APD can continue into adulthood. It has been reported that males are twice as likely to be affected by the disorder as females.^[5][6]

Neurodevelopmental forms of APD are differentiable from aphasia in that aphasia is by definition caused by acquired brain injury, but acquired epileptic aphasia has been viewed as a form of APD.

Signs and symptoms

Many people experience problems with learning and day-to-day tasks with difficulties over time. Individuals with this disorder^[7] may experience the signs and symptoms below;^[8]

• talk louder than necessary
• talk softer than necessary
• have trouble remembering a list or sequence
• often need words or sentences repeated
• have poor ability to memorize information learned by listening
• interpret words too literally
• need assistance hearing clearly in noisy environments
• rely on accommodation and modification strategies
• find or request a quiet work space away from others
• request written material when attending oral presentations
• ask for directions to be given one step at a time

Relation to attention deficit hyperactivity disorder

It has been discovered that APD and ADHD may present overlapping symptoms. Below is a ranked order of behavioral symptoms that are most frequently observed in each disorder. Professionals evaluated the overlap of symptoms between the two disorders. The order below is of symptoms that are almost always observed.^[9] This chart shows that although the symptoms listed are different, it is easy to get confused between many of them.^[10]

ADHD	APD
1. Inattentive	1. Difficult hearing in background noise
2. Distracted	2. Difficulty following oral instructions
3. Hyperactive	3. Poor listening skills
4. Fidgety or restless	4. Academic difficulties
5. Hasty or impulsive	5. Poor auditory association skills
6. Interrupts or intrudes	6. Distracted
	7. Inattentive

There is a co-occurrence between ADHD and APD. A systematic review published in 2018^[11] detailed one study that showed 10% of children with APD have confirmed or suspected ADHD. It also stated that it is sometimes difficult to distinguish the two, since characteristics and symptoms between APD and ADHD tend to overlap. The systematic review mentioned here described this overlap between APD and other behavioral disorders and whether or not it was easy to distinguish those children that solely had auditory processing disorder.^{[citation needed]}

Relation to specific language impairment and developmental dyslexia

There has been considerable debate over the relationship between APD and specific language impairment (SLI).

SLI is diagnosed when a child has difficulties with understanding or producing spoken language for no obvious cause. The problems cannot be explained in terms of peripheral hearing loss. The child is typically late in starting to talk, and may have problems in producing speech sounds clearly, and in producing or understanding complex sentences. Some theoretical accounts of SLI regard it as the result of auditory processing problems.^[12][13] However, this view of SLI is not universally accepted, and others regard the main difficulties in SLI as stemming from problems with higher-level aspects of language processing. Where a child has both auditory and language problems, it can be difficult to sort out the causality at play.^[13]

Similarly with developmental dyslexia, researchers continue to explore the hypothesis that reading problems emerge as a downstream consequence of difficulties in rapid auditory processing. Again, cause and effect can be hard to unravel. This is one reason why some experts have recommended using non-verbal auditory tests to diagnose APD.^[14] Specifically regarding neurological factors, dyslexia has been linked to polymicrogyria which causes cell migrational problems. Children that have polymicrogyri almost always present with deficits on APD testing.^[4] It has also been suggested that APD may be related to cluttering,^[15] a fluency disorder marked by word and phrase repetitions.

It has been found that a higher than expected proportion of individuals diagnosed with SLI and dyslexia on the basis of language and reading tests also perform poorly on tests in which auditory processing skills are tested.^[16][17] APD can be assessed using tests that involve identifying, repeating, or discriminating speech, and a child may do poorly because of primary language problems.^[18] In a study comparing children with a diagnosis of dyslexia and those with a diagnosis of APD, they found the two groups could not be distinguished.^[13][19][20] Analogous results were observed in studies comparing children diagnosed with SLI or APD, the two groups presenting with similar diagnostic criteria.^[21][22] As such, the diagnosis a child receives may depend on which specialist they consult: the same child who might be diagnosed with APD by an audiologist may instead be diagnosed with SLI by a speech-language therapist or with dyslexia by a psychologist.^[14]

Causes

Acquired

Acquired APD can be caused by any damage to or dysfunction of the central auditory nervous system and can cause auditory processing problems.^[23][24] For an overview of neurological aspects of APD, see T. D. Griffiths's 2002 article "Central Auditory Pathologies".^[25]

Genetics

Some studies have indicated an increased prevalence of a family history of hearing impairment in these patients. The pattern of results is suggestive that auditory processing disorder may be related to conditions of autosomal dominant inheritance.^[26][27][28] The ability to listen to and comprehend multiple messages at the same time is a trait that is heavily influenced by our genes, say federal researchers.^[29] These "short circuits in the wiring" sometimes run in families or result from a difficult birth, just like any learning disability.^[30] Auditory processing disorder can be associated with conditions affected by genetic traits, such as various developmental disorders. Inheritance of auditory processing disorder refers to whether the condition is inherited from your parents or "runs" in families.^[31] Central auditory processing disorder may be hereditary neurological traits from the mother or the father.^[32]

Developmental

In the majority of cases of developmental APD, the cause is unknown. An exception is acquired epileptic aphasia or Landau-Kleffner syndrome, where a child's development regresses, with language comprehension severely affected.^[33] The child is often thought to be deaf, but normal peripheral hearing is found. In other cases, suspected or known causes of APD in children include delay in myelin maturation,^[34] ectopic (misplaced) cells in the auditory cortical areas,^[35] or genetic predisposition.^[36] In a family with autosomal dominant epilepsy, seizures which affected the left temporal lobe seemed to cause problems with auditory processing.^[37] In another extended family with a high rate of APD, genetic analysis showed a haplotype in chromosome 12 that fully co-segregated with language impairment.^[38]

Hearing begins in utero, but the central auditory system continues to develop for at least the first decade.^[39] There is considerable interest in the idea that disruption to hearing during a sensitive period may have long-term consequences for auditory development.^[40] One study showed thalamocortical connectivity in vitro was associated with a time sensitive developmental window and required a specific cell adhesion molecule (lcam5) for proper brain plasticity to occur.^[41] This points to connectivity between the thalamus and cortex shortly after being able to hear (in vitro) as at least one critical period for auditory processing. Another study showed that rats reared in a single tone environment during critical periods of development had permanently impaired auditory processing.^[42] "Bad" auditory experiences, such as temporary deafness by cochlear removal in rats leads to neuron shrinkage.^[39] In a study looking at attention in APD patients, children with one ear blocked developed a strong right-ear advantage but were not able to modulate that advantage during directed-attention tasks.^[43]

In the 1980s and 1990s, there was considerable interest in the role of chronic otitis media (middle ear disease or "glue ear") in causing APD and related language and literacy problems. Otitis media with effusion is a very common childhood disease that causes a fluctuating conductive hearing loss, and there was concern this may disrupt auditory development if it occurred during a sensitive period.^[44] Consistent with this, in a sample of young children with chronic ear infections recruited from a hospital otolaryngology department, increased rates of auditory difficulties were found later in childhood.^[45] However, this kind of study will have sampling bias because children with otitis media will be more likely to be referred to hospital departments if they are experiencing developmental difficulties. Compared with hospital studies, epidemiological studies, which assesses a whole population for otitis media and then evaluate outcomes, have found much weaker evidence for long-term impacts of otitis media on language outcomes.^[46]

Somatic

It seems that somatic anxiety (that is, physical symptoms of anxiety such as butterflies in the stomach or cotton mouth) and situations of stress may be determinants of speech-hearing disability.^[47][48]

Diagnosis

Questionnaires can be used for the identification of persons with possible auditory processing disorders, as these address common problems of listening. They can help in the decision for pursuing clinical evaluation. One of the most common listening problems is speech recognition in the presence of background noise.^[49][50] According to the respondents who participated in a study by Neijenhuis, de Wit, and Luinge (2017),^[51] the following symptoms are characteristic in children with listening difficulties, and they are typically problematic with adolescents and adults. They include:^{[citation needed]}

• Difficulty hearing in noise
• Auditory attention problems
• Better understanding in one on one situations
• Difficulties in noise localization
• Difficulties in remembering oral information

According to the New Zealand Guidelines on Auditory Processing Disorders (2017)^[52] a checklist of key symptoms of APD or comorbidities that can be used to identify individuals who should be referred for audiological and APD assessment includes, among others:

• Difficulty following spoken directions unless they are brief and simple
• Difficulty attending to and remembering spoken information
• Slowness in processing spoken information
• Difficulty understanding in the presence of other sounds
• Overwhelmed by complex or "busy" auditory environments e.g. classrooms, shopping malls
• Poor listening skills
• Insensitivity to tone of voice or other nuances of speech
• Acquired brain injury
• History of frequent or persistent middle ear disease (otitis media, "glue ear").
• Difficulty with language, reading, or spelling
• Suspicion or diagnosis of dyslexia
• Suspicion or diagnosis of language disorder or delay

Finally, the New Zealand guidelines state that behavioral checklists and questionnaires should only be used to provide guidance for referrals, for information gathering (for example, prior to assessment or as outcome measures for interventions), and as measures to describe the functional impact of auditory processing disorder. They are not designed for the purpose of diagnosing auditory processing disorders. The New Zealand guidelines indicate that a number of questionnaires have been developed to identify children who might benefit from evaluation of their problems in listening. Examples of available questionnaires include the Fisher's Auditory Problems Checklist,^[53] the Children's Auditory Performance Scale,^[54] the Screening Instrument for Targeting Educational Risk,^[55] and the Auditory Processing Domains Questionnaire^[56] among others. All of the previous questionnaires were designed for children and none are useful for adolescents and adults.^{[citation needed]}

The University of Cincinnati Auditory Processing Inventory (UCAPI)^[57][58] was designed for use with adolescents and adults seeking testing for evaluation of problems with listening and/or to be used following diagnosis of an auditory processing disorder to determine the subject's status. Following a model described by Zoppo et al. (2015^[59]) a 34-item questionnaire was developed that investigates auditory processing abilities in each of the six common areas of complaint in APD (listening and concentration, understanding speech, following spoken instructions, attention, and other.) The final questionnaire was standardized on normally-achieving young adults ranging from 18 to 27 years of age. Validation data was acquired from subjects with language-learning or auditory processing disorders who were either self-reported or confirmed by diagnostic testing. A UCAPI total score is calculated by combining the totals from the six listening conditions and provides an overall value to categorize listening abilities. Additionally, analysis of the scores from the six listening conditions provides an auditory profile for the subject. Each listening condition can then be utilized by the professional in making recommendation for diagnosing problem of learning through listening and treatment decisions. The UCAPI provides information on listening problems in various populations that can aid examiners in making recommendations for assessment and management.^{[citation needed]}

APD has been defined anatomically in terms of the integrity of the auditory areas of the nervous system.^[60] However, children with symptoms of APD typically have no evidence of neurological disease and the diagnosis is made on the basis of performance on behavioral auditory tests. Auditory processing is "what we do with what we hear",^[61] and in APD there is a mismatch between peripheral hearing ability (which is typically normal) and ability to interpret or discriminate sounds. Thus in those with no signs of neurological impairment, APD is diagnosed on the basis of auditory tests. There is, however, no consensus as to which tests should be used for diagnosis, as evidenced by the succession of task force reports that have appeared in recent years. The first of these occurred in 1996.^[62] This was followed by a conference organized by the American Academy of Audiology.^[63]

Experts attempting to define diagnostic criteria have to grapple with the problem that a child may do poorly on an auditory test for reasons other than poor auditory perception: for instance, failure could be due to inattention, difficulty in coping with task demands, or limited language ability. In an attempt to rule out at least some of these factors, the American Academy of Audiology conference explicitly advocated that for APD to be diagnosed, the child must have a modality-specific problem, i.e. affecting auditory but not visual processing. However, a committee of the American Speech-Language-Hearing Association subsequently rejected modality-specificity as a defining characteristic of auditory processing disorders.^[64]

Definitions

in 2005 The American Speech-Language-Hearing Association (ASHA) published "Central Auditory Processing Disorders" as an update to the 1996 "Central Auditory Processing: Current Status of Research and Implications for Clinical Practice".^[64] The American Academy of Audiology has released more current practice guidelines related to the disorder.^[2] ASHA formally defines APD as "a difficulty in the efficiency and effectiveness by which the central nervous system (CNS) utilizes auditory information."^[65]

In 2018, the British Society of Audiology published a "position statement and practice guidance" on auditory processing disorder (APD) updated its definition of APD. According to the Society, APD refers to the inability to process speech and on-speech sounds.^[66]

Auditory processing disorder can be developmental or acquired. It may result from ear infections, head injuries or neurodevelopmental delays that affect processing of auditory information. This can include problems with: "...sound localization and lateralization (see also binaural fusion); auditory discrimination; auditory pattern recognition; temporal aspects of audition, including temporal integration, temporal discrimination (e.g., temporal gap detection), temporal ordering, and temporal masking; auditory performance in competing acoustic signals (including dichotic listening); and auditory performance with degraded acoustic signals".^[62]

The Committee of UK Medical Professionals Steering the UK Auditory Processing Disorder Research Program have developed the following working definition of auditory processing disorder: "APD results from impaired neural function and is characterized by poor recognition, discrimination, separation, grouping, localization, or ordering of speech sounds. It does not solely result from a deficit in general attention, language or other cognitive processes."^[67]

Types of testing

1. The SCAN-C^[68] for children and SCAN-A^[69] for adolescents and adults are the most common tools for screening and diagnosing APD in the USA. Both tests are standardized on a large number of subjects and include validation data on subjects with auditory processing disorders. The SCAN test batteries include screening tests: norm-based criterion-referenced scores; diagnostic tests: scaled scores, percentile ranks and ear advantage scores for all tests except the Gap Detection test. The four tests include four subsets on which the subject scores are derived include: discrimination of monaurally presented single words against background noise (speech in noise), acoustically degraded single words (filtered words), dichotically presented single words and sentences.
2. Random Gap Detection Test (RGDT) is also a standardized test. It assesses an individual's gap detection threshold of tones and white noise. The exam includes stimuli at four different frequencies (500, 1000, 2000, and 4000 Hz) and white noise clicks of 50 ms duration. It is a useful test because it provides an index of auditory temporal resolution. In children, an overall gap detection threshold greater than 20 ms means they have failed and may have an auditory processing disorder based on abnormal perception of sound in the time domain.^[70][71]
3. Gaps in Noise Test (GIN) also measures temporal resolution by testing the patient's gap detection threshold in white noise.^[72]
4. Pitch Patterns Sequence Test (PPT) and Duration Patterns Sequence Test (DPT) measure auditory pattern identification. The PPS has s series of three tones presented at either of two pitches (high or low). Meanwhile, the DPS has a series of three tones that vary in duration rather than pitch (long or short). Patients are then asked to describe the pattern of pitches presented.^[73]
5. Masking Level Difference (MLD) at 500 Hz measures overlapping temporal processing, binaural processing, and low-redundancy by measuring the difference in threshold of an auditory stimulus when a masking noise is presented in and out of phase.^[74]
6. The Staggered Spondaic Word Test (SSW) is one of the oldest tests for APD developed by Jack Katz. Although it has fallen into some disuse by audiologists as it is complicated to score, it is one of the quickest and most sensitive tests to determine APD.

Modality-specificity and controversies

The issue of modality-specificity has led to considerable debate among experts in this field. Cacace and McFarland have argued that APD should be defined as a modality-specific perceptual dysfunction that is not due to peripheral hearing loss.^[75][76] They criticize more inclusive conceptualizations of APD as lacking diagnostic specificity.^[77] A requirement for modality-specificity could potentially avoid including children whose poor auditory performance is due to general factors such as poor attention or memory.^[75][76] Others, however, have argued that a modality-specific approach is too narrow, and that it would miss children who had genuine perceptual problems affecting both visual and auditory processing. It is also impractical, as audiologists do not have access to standardized tests that are visual analogs of auditory tests.^[78] The debate over this issue remains unresolved between modality-specific researchers such as Cacace, and associations such as the American Speech-Language-Hearing Association (among others).^[64] It is clear, however, that a modality-specific approach will diagnose fewer children with APD than a modality-general one, and that the latter approach runs a risk of including children who fail auditory tests for reasons other than poor auditory processing.^[66][64] Although modality-specific testing has been advocated for well over a decade, the visual analog of APD testing has met with sustained resistance from the fields of optometry and ophthalmology.^{[citation needed][editorializing]}

Another controversy concerns the fact that most traditional tests of APD use verbal materials.^[14] The British Society of Audiology^[66] has embraced Moore's (2006) recommendation that tests for APD should assess processing of non-speech sounds.^[14] The concern is that if verbal materials are used to test for APD, then children may fail because of limited language ability. An analogy may be drawn with trying to listen to sounds in a foreign language. It is much harder to distinguish between sounds or to remember a sequence of words in a language you do not know well: the problem is not an auditory one, but rather due to lack of expertise in the language.^[66]

In recent years there have been additional criticisms of some popular tests for diagnosis of APD. Tests that use tape-recorded American English have been shown to over-identify APD in speakers of other forms of English.^[79] Performance on a battery of non-verbal auditory tests devised by the Medical Research Council's Institute of Hearing Research was found to be heavily influenced by non-sensory task demands, and indices of APD had low reliability when this was controlled for.^[80][81] This research undermines the validity of APD as a distinct entity in its own right and suggests that the use of the term "disorder" itself is unwarranted. In a recent review of such diagnostic issues, it was recommended that children with suspected auditory processing impairments receive a holistic psychometric assessment including general intellectual ability, auditory memory, and attention, phonological processing, language, and literacy.^[82] The authors state that "a clearer understanding of the relative contributions of perceptual and non-sensory, unimodal and supramodal factors to performance on psychoacoustic tests may well be the key to unraveling the clinical presentation of these individuals."^[82]

Depending on how it is defined, APD may share common symptoms with ADD/ADHD, specific language impairment, and autism spectrum disorders. A review showed substantial evidence for atypical processing of auditory information in children with autism.^[83] Dawes and Bishop noted how specialists in audiology and speech-language pathology often adopted different approaches to child assessment, and they concluded their review as follows: "We regard it as crucial that these different professional groups work together in carrying out assessment, treatment and management of children and undertaking cross-disciplinary research."^[18] In practice, this seems rare.^{[according to whom?]}

To ensure that APD is correctly diagnosed, the examiners must differentiate APD from other disorders with similar symptoms. Factors that should be taken into account during the diagnosis are: attention, auditory neuropathy, fatigue, hearing and sensitivity, intellectual and developmental age, medications, motivation, motor skills, native language and language experience, response strategies and decision-making style, and visual acuity.^[84]

It should also be noted that children under the age of seven cannot be evaluated correctly because their language and auditory processes are still developing. In addition, the presence of APD cannot be evaluated when a child's primary language is not English.^{[85][ambiguous]}

Characteristics

The American Speech-Language-Hearing Association^[86] state that children with (central) auditory processing disorder often:

• have trouble paying attention to and remembering information presented orally, and may cope better with visually acquired information
• have problems carrying out multi-step directions given orally; need to hear only one direction at a time
• have poor listening skills
• need more time to process information
• have difficulty learning a new language
• have difficulty understanding jokes, sarcasm, and learning songs or nursery rhymes
• have language difficulties (e.g., they confuse syllable sequences and have problems developing vocabulary and understanding language)
• have difficulty with reading, comprehension, spelling, and vocabulary

APD can manifest as problems determining the direction of sounds, difficulty perceiving differences between speech sounds and the sequencing of these sounds into meaningful words, confusing similar sounds such as "hat" with "bat", "there" with "where", etc. Fewer words may be perceived than were actually said, as there can be problems detecting the gaps between words, creating the sense that someone is speaking unfamiliar or nonsense words. In addition, it is common for APD to cause speech errors involving the distortion and substitution of consonant sounds.^[87] Those with APD may have problems relating what has been said with its meaning, despite obvious recognition that a word has been said, as well as repetition of the word. Background noise, such as the sound of a radio, television or a noisy bar can make it difficult to impossible to understand speech, since spoken words may sound distorted either into irrelevant words or words that do not exist, depending on the severity of the auditory processing disorder.^[88] Using a telephone can be problematic for someone with auditory processing disorder, in comparison with someone with normal auditory processing, due to low quality audio, poor signal, intermittent sounds, and the chopping of words. Many who have auditory processing disorder subconsciously develop visual coping strategies, such as lip reading, reading body language, and eye contact, to compensate for their auditory deficit, and these coping strategies are not available when using a telephone.^{[citation needed]}

As noted above, the status of APD as a distinct disorder has been queried, especially by speech-language pathologists^[89] and psychologists,^[90] who note the overlap between clinical profiles of children diagnosed with APD and those with other forms of specific learning disability. Many audiologists, however, would dispute that APD is just an alternative label for dyslexia, SLI, or ADHD, noting that although it often co-occurs with these conditions, it can be found in isolation.^[91]

Subcategories

Based on sensitized measures of auditory dysfunction and on psychological assessment, patients can be subdivided into seven subcategories:^[92]

1. middle ear dysfunction
2. mild cochlear pathology
3. central/medial olivocochlear efferent system (MOCS) auditory dysfunction
4. purely psychological problems
5. multiple auditory pathologies
6. combined auditory dysfunction and psychological problems
7. unknown

Different subgroups may represent different pathogenic and etiological factors. Thus, subcategorization provides further understanding of the basis of auditory processing disorder, and hence may guide the rehabilitative management of these patients. This was suggested by Professor Dafydd Stephens and F Zhao at the Welsh Hearing Institute, Cardiff University.^[93]

Treatment

See also: Alternative therapies for developmental and learning disabilities

Treatment of APD typically focuses on three primary areas: changing learning environment, developing higher-order skills to compensate for the disorder, and remediation of the auditory deficit itself.^[94] However, there is a lack of well-conducted evaluations of intervention using randomized controlled trial methodology. Most evidence for effectiveness adopts weaker standards of evidence, such as showing that performance improves after training. This does not control for possible influences of practice, maturation, or placebo effects. Recent research has shown that practice with basic auditory processing tasks (i.e. auditory training) may improve performance on auditory processing measures^[95][96] and phonemic awareness measures.^[97] Changes after auditory training have also been recorded at the physiological level.^[98][99] Many of these tasks are incorporated into computer-based auditory training programs such as Earobics and Fast ForWord, an adaptive software available at home and in clinics worldwide, but overall, evidence for effectiveness of these computerized interventions in improving language and literacy is not impressive.^[100] One small-scale uncontrolled study reported successful outcomes for children with APD using auditory training software.^[101]

Treating additional issues related to APD can result in success. For example, treatment for phonological disorders (difficulty in speech) can result in success in terms of both the phonological disorder as well as APD. In one study, speech therapy improved auditory evoked potentials (a measure of brain activity in the auditory portions of the brain).^[102]

While there is evidence that language training is effective for improving APD, there is no current research supporting the following APD treatments:

• Auditory Integration Training typically involves a child attending two 30-minute sessions per day for ten days.^[103]
• Lindamood-Bell Learning Processes (particularly, the Visualizing and Verbalizing program)
• Physical activities that require frequent crossing of the midline (e.g., occupational therapy)
• Sound Field Amplification
• Neuro-Sensory Educational Therapy
• Neurofeedback

The use of an individual FM transmitter/receiver system by teachers and students has nevertheless been shown to produce significant improvements with children over time.^[104]

History

Samuel J. Kopetzky first described the condition in 1948. P. F. King, first discussed the etiological factors behind it in 1954.^[105] Helmer Rudolph Myklebust's 1954 study, "Auditory Disorders in Children".^[106] suggested auditory processing disorder was separate from language learning difficulties. His work sparked interest in auditory deficits after acquired brain lesions affecting the temporal lobes^[107][108] and led to additional work looking at the physiological basis of auditory processing,^[109] but it was not until the late seventies and early eighties that research began on APD in depth.

In 1977, the first conference on the topic of APD was organized by Robert W. Keith, Ph.D. at the University of Cincinnati. The proceedings of that conference was published by Grune and Stratton under the title "Central Auditory Dysfunction" (Keith RW Ed.) That conference started a new series of studies focusing on APD in children.^{[110][111][112][113][114]} Virtually all tests currently used to diagnose APD originate from this work. These early researchers also invented many of the auditory training approaches, including interhemispheric transfer training and interaural intensity difference training. This period gave us a rough understanding of the causes and possible treatment options for APD.

Much of the work in the late nineties and 2000s has been looking to refining testing, developing more sophisticated treatment options, and looking for genetic risk factors for APD. Scientists have worked on improving behavioral tests of auditory function, neuroimaging, electroacoustic, and electrophysiologic testing.^[115][116] Working with new technology has led to a number of software programs for auditory training.^[117][118] With global awareness of mental disorders and increasing understanding of neuroscience, auditory processing is more in the public and academic consciousness than in years past.^{[119][120][121][122]}

See also

• Amblyaudia
• Auditory verbal agnosia
• Cocktail party effect
• Cortical deafness
• Dafydd Stephens
• Echoic memory
• Hearing loss
• Language processing
• List of eponymous diseases
• Music-specific disorders
• Selective auditory attention
• Selective mutism
• Sensory processing disorders
• Spatial hearing loss

References

1. Griffiths, Timothy (2002). "Central Auditory Pathologies". British Medical Bulletin. 63 (63): 107–120. doi:10.1093/bmb/63.1.107. PMID 12324387.
2. American Academy of Audiology. "Clinical Practice Guidelines: Diagnosis, Treatment and Management of Children and Adults with Central Auditory" (PDF). Retrieved 16 January 2017.
3. Aristidou, Isaac L.; Hohman, Marc H. (2023), "Central Auditory Processing Disorder", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 36508531, retrieved 2023-05-19
4. Chermak, Gail; Musiek, Frank (2014). Handbook of central auditory processing disorder. comprehensive intervention (2 ed.). San Diego, CA: Plural Publishing. ISBN 978-1-59756-562-2.
5. La Trobe University. "(C)APD". Retrieved 14 November 2010.
6. Musiek, Frank; Gail, Chermak (2007). Handbook of central auditory processing disorder [auditory neuroscience and diagnosis]. Plural Publishing. p. 448. ISBN 978-1-59756-056-6.
7. National Center for Learning Disabilities | NCLD.org – NCLD. National Center for Learning Disabilities | NCLD.org – NCLD. N.p., n.d. Web. 19 November 2014.
8. Bamiou, D.-E.; Musiek, F. E.; Luxon, L. M. (2001-11-01). "Aetiology and clinical presentations of auditory processing disorders—a review". Archives of Disease in Childhood. 85 (5): 361–365. doi:10.1136/adc.85.5.361. ISSN 0003-9888. PMC 1718975. PMID 11668093.
9. Chermak, Gail D.; Somers, Erin K.; Seikel, J. Anthony (1998). "Behavioral signs of central auditory processing disorder and attention deficit hyperactivity disorder". Journal of American Academy of Audiology. 9 (1): 78–84. PMID 9493945.
10. de Wit, Ellen; van Dijk, Pim; Hanekamp, Sandra; Visser-Bochane, Margot I.; Steenbergen, Bert; van der Schans, Cees P.; Luinge, Margreet R. (January 2018). "Same or Different: The Overlap Between Children With Auditory Processing Disorders and Children With Other Developmental Disorders: A Systematic Review". Ear and Hearing. 39 (1): 1–19. doi:10.1097/AUD.0000000000000479. ISSN 0196-0202. PMC 7654752. PMID 28863035.
11. de Wit, Ellen; van Dijk, Pim; Hanekamp, Sandra; Visser-Bochane, Margot I.; Steenbergen, Bert; van der Schans, Cees P.; Luinge, Margreet R. (2018). "Same or Different: The Overlap Between Children With Auditory Processing Disorders and Children With Other Developmental Disorders: A Systematic Review". Ear and Hearing. 39 (1): 1–19. doi:10.1097/AUD.0000000000000479. PMC 7654752. PMID 28863035.
12. Miller, C. A. (2011). "Auditory processing theories of language disorders: Past, present, and future". Language, Speech, and Hearing Services in Schools. 42 (3): 309–319. doi:10.1044/0161-1461(2011/10-0040). PMID 21757567. S2CID 17500092.
13. Ferguson, M. A.; Hall, R. L.; Riley, A; Moore, D. R. (2011). "Communication, listening, cognitive and speech perception skills in children with auditory processing disorder (APD) or specific language impairment (SLI)". Journal of Speech, Language, and Hearing Research. 54 (1): 211–227. doi:10.1044/1092-4388(2010/09-0167). PMID 20689032.
14. Moore, David R. (2006). "Auditory processing disorder (APD): Definition, diagnosis, neural basis, and intervention". Audiological Medicine. 4 (1): 4–11. doi:10.1080/16513860600568573. S2CID 145753219.
15. Pindzola, Rebekah H.; Haynes, William O.; Moran, Michael J. (2006). Communication disorders in the classroom: an introduction for professionals in school setting. Boston: Jones and Bartlett Publishers. p. 251. ISBN 978-0-7637-2743-7. OCLC 59401841.
16. Moore, David R. (July 2007). "Auditory processing disorders: Acquisition and treatment". Journal of Communication Disorders. 40 (4): 295–304. doi:10.1016/j.jcomdis.2007.03.005. PMID 17467002.
17. Kalaiah M (2015). "Relation between phonological processing, auditory processing and speech perception among bilingual poor readers". Korean Journal of Audiology. 19 (3): 125–131. doi:10.7874/jao.2015.19.3.125. PMC 4704549. PMID 26771010. S2CID 488841.
18. Dawes P, Bishop D (2009). "Auditory processing disorder in relation to developmental disorders of language, communication and attention: a review and critique". Int J Lang Commun Disord. 44 (4): 440–65. doi:10.1080/13682820902929073. PMID 19925352.
19. Dawes, P; Bishop, D (2010). "Psychometric profile of children with auditory processing disorder (APD) and children with dyslexia". Archives of Disease in Childhood. 95 (6): 432–436. doi:10.1136/adc.2009.170118. PMC 3576918. PMID 20501538.
20. Miller, C.A.; Wagstaff, D.A. (2011). "Behavioral profiles associated with auditory processing disorder and specific language impairment". Journal of Communication Disorders. 44 (6): 745–763. doi:10.1016/j.jcomdis.2011.04.001. PMC 3174343. PMID 21636094.
21. Corriveau K, Pasquini E, Goswami U (June 2007). "Basic auditory processing skills and specific language impairment: a new look at an old hypothesis". J. Speech Lang. Hear. Res. 50 (3): 647–66. doi:10.1044/1092-4388(2007/046). PMID 17538107. S2CID 1074440.
22. Dlouha O, Novak A, Vokral J (June 2007). "Central auditory processing disorder (CAPD) in children with specific language impairment (SLI). Central auditory tests". Int. J. Pediatr. Otorhinolaryngol. 71 (6): 903–7. doi:10.1016/j.ijporl.2007.02.012. PMID 17382411.
23. Musiek FE, Chermak GD, Weihing J, Zappulla M, Nagle S (June 2011). "Diagnostic accuracy of established central auditory processing test batteries in patients with documented brain lesions". J Am Acad Audiol. 22 (6): 342–58. doi:10.3766/jaaa.22.6.4. PMID 21864472.
24. Lew HL, Weihing J, Myers PJ, Pogoda TK, Goodrich GL (2010). "Dual sensory impairment (DSI) in traumatic brain injury (TBI)--An emerging interdisciplinary challenge". NeuroRehabilitation. 26 (3): 213–22. doi:10.3233/NRE-2010-0557. PMID 20448311.
25. Griffiths, T. D. (2002). "Central auditory pathologies". British Medical Bulletin. 63 (1): 107–120. doi:10.1093/bmb/63.1.107. PMID 12324387.
26. Stephens D, Zhao F (March 2000). "The role of a family history in King Kopetzky Syndrome (obscure auditory dysfunction)". Acta Otolaryngol. 120 (2): 197–200. doi:10.1080/000164800750000900. PMID 11603771. S2CID 45623565.
27. Liu XZ, Xu L, Newton V. "Audiometric configuration in non-syndromic genetic hearing loss". J Audiol Med. 3: 99–106.
28. Van Camp G, Willems PJ, Smith RJ (1997). "Non-syndromic hearing impairment: unparalleled heterogeneity". Am J Genet. 60: 758–64.
29. ("Genetics Influence Auditory Processing." Psych Central.com. N.p., n.d. Web. 2 December 2014.)
30. (NCLD.org – NCLD." National Center for Learning Disabilities | NCLD.org.)
31. ("Inheritance and Genetics of Auditory Processing Disorder." – RightDiagnosis.com. N.p., n.d. Web. 2 December 2014.)
32. Brewer CC, Zalewski CK, King KA (10 May 2020). "Heritability of non-speech auditory processing skills". European Journal of Human Genetics. Eur J Hum Genet. 24 (8): 1137–1144. doi:10.1038/ejhg.2015.277. PMC 4872837. PMID 26883091.
33. Fandiño M, Connolly M, Usher L, Palm S, Kozak FK (January 2011). "Landau-Kleffner syndrome: a rare auditory processing disorder series of cases and review of the literature". Int. J. Pediatr. Otorhinolaryngol. 75 (1): 33–8. doi:10.1016/j.ijporl.2010.10.001. PMID 21074868.
34. Weihing, Jeff; Musiek, Frank (2007). "15 Dichotic Interaural Intensity Difference (DIID)". In Ross-Swain, Deborah; Geffner, Donna S (eds.). Auditory Processing Disorders: Assessment, Management and Treatment. Plural Publishing Inc. ISBN 978-1-59756-107-5. OCLC 255602759.
35. Boscariol M, Garcia VL, Guimarães CA, et al. (April 2010). "Auditory processing disorder in perisylvian syndrome". Brain Dev. 32 (4): 299–304. doi:10.1016/j.braindev.2009.04.002. PMID 19410403. S2CID 6078682.
36. Bamiou DE, Campbell NG, Musiek FE, et al. (April 2007). "Auditory and verbal working memory deficits in a child with congenital aniridia due to a PAX6 mutation". Int J Audiol. 46 (4): 196–202. doi:10.1080/14992020601175952. PMID 17454233. S2CID 45483072.
37. Pisano T, Marini C, Brovedani P, Brizzolara D, Pruna D, Mei D, Moro F, Cianchetti C, Guerrini R (January 2005). "Abnormal phonologic processing in familial lateral temporal lobe epilepsy due to a new LGI1 mutation". Epilepsia. 46 (1): 118–23. doi:10.1111/j.0013-9580.2005.26304.x. PMID 15660777. S2CID 19751059.
38. Addis L, Friederici AD, Kotz SA, Sabisch B, Barry J, Richter N, Ludwig AA, Rübsamen R, Albert FW, Pääbo S, Newbury DF, Monaco AP (August 2010). "A locus for an auditory processing deficit and language impairment in an extended pedigree maps to 12p13.31-q14.3". Genes, Brain and Behavior. 9 (6): 545–61. doi:10.1111/j.1601-183X.2010.00583.x. PMC 2948670. PMID 20345892.
39. Moore DR (2002). "Auditory development and the role of experience". British Medical Bulletin. 63: 171–81. doi:10.1093/bmb/63.1.171. PMID 12324392.
40. Thai-Van H, Veuillet E, Norena A, Guiraud J, Collet L (March 2010). "Plasticity of tonotopic maps in humans: influence of hearing loss, hearing aids and cochlear implants". Acta Otolaryngol. 130 (3): 333–7. doi:10.3109/00016480903258024. PMID 19845491. S2CID 27423669.
41. Barkat TR, Polley DB, Hensch TK (September 2011). "A critical period for auditory thalamocortical connectivity". Nature Neuroscience. 14 (9): 1189–94. doi:10.1038/nn.2882. PMC 3419581. PMID 21804538.
42. Han YK, Köver H, Insanally MN, Semerdjian JH, Bao S (September 2007). "Early experience impairs perceptual discrimination". Nature Neuroscience. 10 (9): 1191–7. doi:10.1038/nn1941. PMID 17660815. S2CID 11772101.
43. Asbjørnsen A, Holmefjord A, Reisaeter S, Møller P, Klausen O, Prytz B, Boliek C, Obrzut JE (July 2000). "Lasting auditory attention impairment after persistent middle ear infections: a dichotic listening study". Developmental Medicine and Child Neurology. 42 (7): 481–6. doi:10.1111/j.1469-8749.2000.tb00352.x. PMID 10972421. S2CID 77979.
44. Whitton JP, Polley DB (October 2011). "Evaluating the perceptual and pathophysiological consequences of auditory deprivation in early postnatal life: a comparison of basic and clinical studies". J. Assoc. Res. Otolaryngol. 12 (5): 535–47. doi:10.1007/s10162-011-0271-6. PMC 3173557. PMID 21607783.
45. Hartley DE, Moore DR (June 2005). "Effects of otitis media with effusion on auditory temporal resolution". International Journal of Pediatric Otorhinolaryngology. 69 (6): 757–69. doi:10.1016/j.ijporl.2005.01.009. PMID 15885328.
46. Feldman, H.M.; et al. (2003). "Parent-reported language skills in relation to otitis media during the first 3 years of life". Journal of Speech, Language, and Hearing Research. 46 (2): 273–287. doi:10.1044/1092-4388(2003/022). PMID 14700371.
47. Zhao F, Stephens D (1996). "Determinants of speech-hearing disability in King-Kopetzky syndrome". Scand Audiol. 25 (2): 91–6. doi:10.3109/01050399609047989. PMID 8738633.
48. King K, Stephens D (1992). "Auditory and psychological factors in 'auditory disability with normal hearing'". Scand Audiol. 21 (2): 109–14. doi:10.3109/01050399209045990. PMID 1641572.
49. Jerger, James; Musiek, Frank (October 2000). "Report of the Consensus Conference on the Diagnosis of Auditory Processing Disorders in School-Aged Children" (PDF). Journal of the American Academy of Audiology. 11 (9): 467–74. doi:10.1055/s-0042-1748136. PMID 11057730. S2CID 18887683.
50. Working Group on Auditory Processing Disorders (2005). "(Central) Auditory Processing Disorders—The Role of the Audiologist [Position Statement]". American Speech-Language-Hearing Association. doi:10.1044/policy.PS2005-00114.
51. Neijenhuis, Karin; de Wit, Ellen; Luinge, Margreet (13 July 2017). "Perspectives of Dutch health professionals regarding auditory processing disorders; a focus group study". International Journal of Audiology. 56 (12): 942–950. doi:10.1080/14992027.2017.1347290. PMID 28701055. S2CID 30517252.
52. Keith, W.J., Purdy, S.C., Baily, M., Kay, Flora. Draft of New Zealand APD Guidelines on Auditory Processing Disorder (2018) Published by the Auditory Processing Disorders Reference Group, New Zealand Audiological Society.
53. Fisher, L. I. (1976). Fisher's Auditory Problems Checklist. Tampa, FL. The Educational Audiology Association
54. Smoski, W.J., Brung, M.A.. and Tannahill, J.C., (1998) Children's Auditory Performance Scale, Tampa, FL: The Educational Audiology Association
55. Anderson, K. (1989). SIFTER: Screening instrument for targeting educational risk in children identified by hearing screening or who have known hearing loss. Tampa, FL The Educational Audiology Association
56. O'Hara, Brian; Mealings, Kiri (31 July 2018). "Developing the auditory processing domains questionnaire (APDQ): a differential screening tool for auditory processing disorder". International Journal of Audiology. 57 (10): 764–775. doi:10.1080/14992027.2018.1487087. PMID 30063869. S2CID 51886769.
57. Keith, R.W., Tektas, M., and Ramsay, K. (2018) Development of the University of Cincinnati Auditory Processing Inventory for Adolescents and Adults (UCAPI), American Academy of Audiology Annual Conference. April 18–21, 2018, Nashville, TN. Research Podium Presentation. Published in the International Journal of Audiology (IJA), 58:6. 373-378, 2019 under the same title. DOI:10.1080/14992027.1585973
58. Keith, Robert W.; Tektas, Melisa; Ramsay, Kendall; Delaney, Sarah (2019). "Development and standardization of the University of Cincinnati Auditory Processing Inventory (UCAPI)†". International Journal of Audiology. 58 (6): 373–378. doi:10.1080/14992027.2019.1585973. ISSN 1708-8186. PMID 30939055. S2CID 92999722.
59. Del Zoppo, C.; Sanchez, L.; Lind, C. (2015). "A long-term follow-up of children and adolescents referred for assessment of auditory processing disorder". International Journal of Audiology. 54 (6): 368–375. doi:10.3109/14992027.2014.972523. PMID 25544358. S2CID 13567744.
60. Rintelmann, W.F. (1985). "Monaural speech tests in the detection of central auditory disorders.". In Marilyn L Pinheiro; Frank E Musiek (eds.). Assessment of central auditory dysfunction: foundations and clinical correlates. Baltimore: Williams & Wilkins. pp. 173–200. ISBN 978-0-683-06887-0. OCLC 11497885.
61. Katz, Jack (1992). "Classification of auditory processing disorders". In Jack Katz; Nancy Austin Stecker; Donald Henderson (eds.). Central auditory processing: a transdisciplinary view. St. Louis: Mosby Year Book. pp. 81–92. ISBN 978-1-55664-372-9. OCLC 25877287.
62. Task Force on Central Auditory Processing Consensus Development, American Speech-Language-Hearing Association (1996). "Central Auditory Processing: Current Status of Research and Implications for Clinical Practice". American Journal of Audiology. 5 (2): 41–52. doi:10.1044/1059-0889.0502.41. Retrieved 23 October 2020.
63. Jerger J, Musiek F (October 2000). "Report of the Consensus Conference on the Diagnosis of Auditory Processing Disorders in School-Aged Children". J Am Acad Audiol. 11 (9): 467–74. doi:10.1055/s-0042-1748136. PMID 11057730. S2CID 18887683.
64. "(Central) Auditory Processing Disorders [technical report]". American Speech-Language-Hearing Association. Rockville (MD): ASHA. 2005. Retrieved 23 October 2020.
65. Paul, Rhea (25 August 2007). "Auditory Processing Disorder". Journal of Autism and Developmental Disorders. 38 (1): 208–209. doi:10.1007/s10803-007-0437-6. PMID 17721695. S2CID 33085064.
66. British Society of Audiology (2018). Auditory Processing Disorder (APD) (PDF). London, England: British Society of Audiology. Retrieved 23 October 2020.
67. "British Society of Audiology - BSA". British Society of Audiology.
68. Keith, Robert W. (2000). "SCAN-C Test for Auditory Processing Dis- orders in Children". Revised, Psychological Corporation.
69. Keith, Robert (2009). "SCAN-3:A Tests for Auditory Processing Disorders in Adolescents and Adults". Pearson US. {{cite journal}}: Cite journal requires |journal= (help)
70. Muluk, Nuray Bayar; Yalçınkaya, Fulya; Keith, Robert W. (February 2011). "Random gap detection test and random gap detection test-expanded: Results in children with previous language delay in early childhood". Auris Nasus Larynx. 38 (1): 6–13. doi:10.1016/j.anl.2010.05.007. ISSN 0385-8146. PMID 20599334.
71. Keith, Robert W. (2011). "Random gap detection test". {{cite journal}}: Cite journal requires |journal= (help)
72. Musiek, Frank E.; Shinn, Jennifer B.; Jirsa, Robert; Bamiou, Doris-Eva; Baran, Jane A.; Zaida, Elena (December 2005). "GIN (Gaps-In-Noise) Test Performance in Subjects with Confirmed Central Auditory Nervous System Involvement". Ear and Hearing. 26 (6): 608–618. doi:10.1097/01.aud.0000188069.80699.41. PMID 16377996. S2CID 25534002.
73. Musiek, Frank (1994). "Frequency (Pitch) and Duration Pattern Tests". Journal of the American Academy of Audiology. 5 (4): 265–268. PMID 7949300.
74. Brown, Mallory; Musiek, Frank (January 2013). "Pathways: The Fundamentals of Masking Level Differences for Assessing Auditory Function". The Hearing Journal. 66 (1): 16. doi:10.1097/01.HJ.0000425772.41884.1d. ISSN 0745-7472.
75. Cacace, Anthony T.; Dennis J. McFarland (July 1995). . American Journal of Audiology. 4 (2): 61–62. doi:10.1044/1059-0889.0402.61. Archived from the original on 2011-01-27. Retrieved 2010-08-31.
76. Cacace, Anthony T.; Dennis J. McFarland (December 2005). "The Importance of Modality Specificity in Diagnosing Central Auditory Processing Disorder". American Journal of Audiology. 14 (2): 112–123. doi:10.1044/1059-0889(2005/012). PMID 16489868.
77. Cacace, A.T.; McFarland, D.J. (1998). "Central auditory processing disorder in school-aged children: a critical review". Journal of Speech, Language, and Hearing Research. 41 (2): 355–73. doi:10.1044/jslhr.4102.355. PMID 9570588. Retrieved 23 October 2020.
78. Bellis, Teri James; Ross, Jody (2011). "Performance of normal adults and children on central auditory diagnostic tests and their corresponding visual analogs". Journal of the American Academy of Audiology. 22 (8): 491–500. doi:10.3766/jaaa.22.8.2. PMID 22031674. Retrieved 23 October 2020.
79. Dawes, P; Bishop, D.V. M. (2007). "The SCAN-C in testing for auditory processing disorder in a sample of British children". International Journal of Audiology. 46 (12): 780–786. doi:10.1080/14992020701545906. PMID 18049967. S2CID 20449768.
80. Moore, D.R.; Ferguson, M.A.; Edmondson-Jones, A.M.; Ratib, S; Riley, A (2010). "Nature of auditory processing disorder in children". Pediatrics. 126 (2): e382–390. doi:10.1542/peds.2009-2826. PMID 20660546. S2CID 34412421.
81. Moore, D.R.; Cowan, J.A.; Riley, A; Edmondson-Jones, A.M.; Ferguson, M.A. (2011). "Development of auditory processing in 6-11 year old children". Ear and Hearing. 32 (3): 269–285. doi:10.1097/AUD.0b013e318201c468. PMID 21233712. S2CID 36072231.
82. Cowan J, Rosen S, Moore DR (2009). "Putting the Auditory Processing Back into Auditory Processing Disorder in Children". In Cacace AT, McFarland DJ (eds.). Controversies in central auditory processing disorder. San Diego, Calif.; Abingdon. pp. 187–197. ISBN 978-159-756260-7.{{cite book}}: CS1 maint: location missing publisher (link)
83. O'Connor K (December 2011). "Auditory processing in autism spectrum disorder: A review". Neurosci Biobehav Rev. 36 (2): 836–54. doi:10.1016/j.neubiorev.2011.11.008. PMID 22155284. S2CID 13991425.
84. Jerger, James; Musick, Frank (2000). "Report of the Consensus Conference on the Diagnosis of Auditory Processing Disorders in School-Aged Children". Journal of the American Academy of Audiology. 11 (9): 467–474. doi:10.1055/s-0042-1748136. PMID 11057730. S2CID 18887683.
85. Brandstaetter, Patt; Hunter, Lisa; Kalweit, Linda; Kloos, Eric; Landrud, Sherry; Larson, Nancy; Packer, Amy; Wall, Deb (2003). "Introduction to Auditory Processing Disorders". Minnesota Department of Education Total Special Education System.
86. "Central Auditory Processing Disorder: Signs and Symptoms". American Speech-Language-Hearing Association. Retrieved 23 October 2020.
87. DeVore, Brooke; Nagao, Kyoko; Pereira, Olivia; Nemith, Julianne; Sklar, Rachele; Deeves, Emily; Kish, Emily; Welsh, Kelsey; Morlet, Thierry (2016). Speech errors among children with auditory processing disorder. Proceedings of Meetings on Acoustics. Vol. 29. p. 6. doi:10.1121/2.0000440.
88. Anderson S, Kraus N (October 2010). "Sensory-cognitive interaction in the neural encoding of speech in noise: a review". J Am Acad Audiol. 21 (9): 575–85. doi:10.3766/jaaa.21.9.3. PMC 3075209. PMID 21241645.
89. Kamhi, A.G. (2011). "What speech-language pathologists need to know about Auditory Processing Disorder". Language, Speech, and Hearing Services in Schools. 42 (3): 265–272. doi:10.1044/0161-1461(2010/10-0004). PMID 20844272. S2CID 18198216.
90. Lovett, B.J. (2011). "Auditory processing disorder: School psychologist beware?". Psychology in the Schools. 48 (8): 855–867. doi:10.1002/pits.20595.
91. Chermak, Gail D (2001). "Auditory processing disorder: An overview for the clinician". Hearing Journal. 54 (7): 10–25. doi:10.1097/01.HJ.0000294109.14504.d8. S2CID 147238455.
92. Zhao F, Stephens D (August 2000). "Subcategories of patients with Auditory Processing Disorder". Br J Audiol. 34 (4): 241–56. doi:10.3109/03005364000000134. PMID 10997453. S2CID 13246195.
93. "Subcategories of Patients with King-Kopetzky Syndrome". British Journal of Audiology. doi:10.3109/03005364000000134 – via informahealthcare.com.
94. Bellis, Teri James. "Auditory Processing Disorders (APD) in Children". www.asha.org. ASHA.
95. Chermak GD, Silva ME, Nye J, Hasbrouck J, Musiek FE (May 2007). "An update on professional education and clinical practices in central auditory processing". J Am Acad Audiol. 18 (5): 428–52, quiz 455. doi:10.3766/jaaa.18.5.7. PMID 17715652. S2CID 36265513.
96. Moore DR (2007). "Auditory processing disorders: acquisition and treatment". J Commun Disord. 40 (4): 295–304. doi:10.1016/j.jcomdis.2007.03.005. PMID 17467002.
97. Moore DR, Rosenberg JF, Coleman JS (July 2005). "Discrimination training of phonemic contrasts enhances phonological processing in mainstream school children". Brain Lang. 94 (1): 72–85. doi:10.1016/j.bandl.2004.11.009. PMID 15896385. S2CID 3895590.
98. Russo NM, Nicol TG, Zecker SG, Hayes EA, Kraus N (January 2005). "Auditory training improves neural timing in the human brainstem". Behav. Brain Res. 156 (1): 95–103. doi:10.1016/j.bbr.2004.05.012. PMID 15474654. S2CID 332303.
99. Alonso R, Schochat E (2009). "The efficacy of formal auditory training in children with (central) auditory processing disorder: behavioral and electrophysiological evaluation". Braz J Otorhinolaryngol. 75 (5): 726–32. doi:10.1590/S1808-86942009000500019. PMC 9442236. PMID 19893943.
100. Loo, J.H.Y.; Bamiou, D.-E.; Campbell, N.; Luxon, L.M. (2010). "Computer-based auditory training (CBAT): benefits for children with language- and reading-related learning difficulties". Developmental Medicine and Child Neurology. 52 (8): 708–717. doi:10.1111/j.1469-8749.2010.03654.x. PMID 20370814.
101. Cameron S, Dillon H (November 2011). "Development and Evaluation of the LiSN & Learn Auditory Training Software for Deficit-Specific Remediation of Binaural Processing Deficits in Children: Preliminary Findings". Journal of the American Academy of Audiology. 22 (10): 678–96. doi:10.3766/jaaa.22.10.6. PMID 22212767.
102. Leite RA, Wertzner HF, Matas CG (2010). "Long latency auditory evoked potentials in children with phonological disorder". Pró-fono: Revista de Atualização Científica. 22 (4): 561–6. doi:10.1590/s0104-56872010000400034. PMID 21271117.
103. Mudford OC, Cullen C (2004). "Auditory integration training: a critical review". In Jacobson JW, Foxx RM, Mulick JA (eds.). Controversial Therapies for Developmental Disabilities. Routledge. pp. 351–62. ISBN 978-0-8058-4192-3.
104. Sharma, Mridula & Purdy, Suzanne & Kelly, Andrea (2012). "A Randomized Control Trial of Interventions In School-Aged Children with Auditory Processing Disorders". International Journal of Audiology. 51 (7): 506–18. doi:10.3109/14992027.2012.670272. PMID 22512470. S2CID 25414619.{{cite journal}}: CS1 maint: multiple names: authors list (link)
105. Stephens, D.; Zhao, F.; Kennedy, V. (July 2003). "Is there an association between noise exposure and King Kopetzky Syndrome?". Noise and Health. 5 (20): 55–62. PMID 14558893. Retrieved 31 July 2010.
106. Myklebust, H. (1954). Auditory disorders in children. New York: Grune & Stratton. OCLC 553322
107. Bocca E, Calearo C, Cassinari V (1954). "A new method for testing hearing in temporal lobe tumours; preliminary report". Acta Oto-Laryngologica. 44 (3): 219–21. doi:10.3109/00016485409128700. PMID 13197002.
108. Bocca E, Calearo C, Cassinari V, Migliavacca F (1955). "Testing "cortical" hearing in temporal lobe tumours". Acta Oto-Laryngologica. 45 (4): 289–304. doi:10.3109/00016485509124282. PMID 13275293.
109. Kimura, Doreen (1961). "Cerebral dominance and the perception of verbal stimuli". Canadian Journal of Psychology. 15 (3): 166–171. doi:10.1037/h0083219. ISSN 0008-4255.
110. Katz, J., & Illmer, R. (1972). Auditory perception in children with learning disabilities. In J. Katz (Ed.), Handbook of clinical audiology (pp. 540–563). Baltimore: Williams & Wilkins. OCoLC 607728817
111. Keith, Robert W. (1977). Central auditory dysfunction: University of Cincinnati Medical Center Division of Audiology and Speech Pathology symposium. New York: Grune & Stratton. ISBN 978-0-8089-1061-9. OCLC 3203948.
112. Sweetow RW, Reddell RC (1978). "The use of masking level differences in the identification of children with perceptual problems". J Am Audiol Soc. 4 (2): 52–6. PMID 738915.
113. Manning WH, Johnston KL, Beasley DS (February 1977). "The performance of children with auditory perceptual disorders on a time-compressed speech discrimination measure". J Speech Hear Disord. 42 (1): 77–84. doi:10.1044/jshd.4201.77. PMID 839757.
114. Willeford, J. A. (1977). "Assessing central auditory behavior in children A test battery approach". In Keith, Robert W. (ed.). Central auditory dysfunction. New York: Grune & Stratton. pp. 43–72. ISBN 978-0-8089-1061-9. OCLC 3203948.
115. Jerger J, Thibodeau L, Martin J, et al. (September 2002). "Behavioral and electrophysiologic evidence of auditory processing disorder: a twin study". J Am Acad Audiol. 13 (8): 438–60. doi:10.1055/s-0040-1716007. PMID 12371661.
116. Estes RI, Jerger J, Jacobson G (February 2002). "Reversal of hemispheric asymmetry on auditory tasks in children who are poor listeners". J Am Acad Audiol. 13 (2): 59–71. doi:10.1055/s-0040-1715949. PMID 11895008.
117. Chermak GD, Musiek FE (2002). "Auditory training: Principles and approaches for remediation and managing auditory processing disorders". Seminars in Hearing. 23 (4): 287–295. doi:10.1055/s-2002-35878. ISSN 0734-0451.
118. Musiek F (June 1999). "Habilitation and management of auditory processing disorders: overview of selected procedures". J Am Acad Audiol. 10 (6): 329–42. doi:10.1055/s-0042-1748504. PMID 10385875. S2CID 11936281.
119. Jerger J, Musiek F (October 2000). (PDF). J Am Acad Audiol. 11 (9): 467–74. doi:10.1055/s-0042-1748136. PMID 11057730. S2CID 18887683. Archived from the original (PDF) on 2013-06-21. Retrieved 2012-05-24.
120. Keith, Robert W. (1981). Central auditory and language disorders in children. San Diego, CA: College-Hill Press. ISBN 978-0-933014-74-9. OCLC 9258682.
121. Katz, Jack; Henderson, Donald; Stecker, Nancy Austin (1992). Central auditory processing: a transdisciplinary view. St. Louis, MO: Mosby Year Book. ISBN 978-1-55664-372-9. OCLC 2587728.
122. Katz, Jack; Stecker, Nancy Austin (1998). Central auditory processing disorders: mostly management. Boston: Allyn and Bacon. ISBN 978-0-205-27361-4. OCLC 246378171.

External links

• Auditory processing disorder: An overview for the clinician