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Wikipedia

5-Hydroxyisourate

5-Hydroxyisourate is an organic compound that is produced by the oxidation of uric acid. The conversion is a major pathway in the antioxidant properties of urate. The conversion is catalysed by urate oxidase.[1][2]

5-Hydroxyisourate
Names
IUPAC name
5-hydroxy-3,7-dihydropurine-2,6,8-trione
Identifiers
  • 6960-30-1 Y
3D model (JSmol)
  • Interactive image
  • Interactive image
ChEBI
  • CHEBI:18072 Y
ChemSpider
  • 219288 Y
KEGG
  • C11821 Y
MeSH 5-Hydroxyisourate
  • 250388
UNII
  • DU6PJ7L9BX Y
  • DTXSID10290591
  • InChI=1S/C5H4N4O4/c10-2-5(13)1(6-3(11)8-2)7-4(12)9-5/h13H,(H3,6,7,8,9,10,11,12) Y
    Key: LTQYPAVLAYVKTK-UHFFFAOYSA-N Y
  • InChI=1/C5H4N4O4/c10-2-5(13)1(6-3(11)8-2)7-4(12)9-5/h13H,(H3,6,7,8,9,10,11,12)
    Key: LTQYPAVLAYVKTK-UHFFFAOYAS
  • C12=NC(=O)NC1(C(=O)NC(=O)N2)O
  • O=C1NC(=O)N/C2=N/C(=O)NC12O
Properties
C5H4N4O4
Molar mass 184.11 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
sequence of oxidation of ureate.

5-Hydroxyisourate rearranges to allantoin.

References edit

  1. ^ Oksanen E, Blakeley MP, El-Hajji M, Ryde U, Budayova-Spano M (2014-01-23). "The Neutron Structure of Urate Oxidase Resolves a Long-Standing Mechanistic Conundrum and Reveals Unexpected Changes in Protonation". PLOS ONE. 9 (1): e86651. Bibcode:2014PLoSO...986651O. doi:10.1371/journal.pone.0086651. PMC 3900588. PMID 24466188.
  2. ^ Fetzner, Susanne; Steiner, Roberto A. (2010). "Cofactor-independent oxidases and oxygenases". Applied Microbiology and Biotechnology. 86 (3): 791–804. doi:10.1007/s00253-010-2455-0. PMID 20157809. S2CID 25377247.

See also edit



hydroxyisourate, organic, compound, that, produced, oxidation, uric, acid, conversion, major, pathway, antioxidant, properties, urate, conversion, catalysed, urate, oxidase, names, iupac, name, hydroxy, dihydropurine, trione, identifiers, number, 6960, model, . 5 Hydroxyisourate is an organic compound that is produced by the oxidation of uric acid The conversion is a major pathway in the antioxidant properties of urate The conversion is catalysed by urate oxidase 1 2 5 Hydroxyisourate Names IUPAC name 5 hydroxy 3 7 dihydropurine 2 6 8 trione Identifiers CAS Number 6960 30 1 Y 3D model JSmol Interactive imageInteractive image ChEBI CHEBI 18072 Y ChemSpider 219288 Y KEGG C11821 Y MeSH 5 Hydroxyisourate PubChem CID 250388 UNII DU6PJ7L9BX Y CompTox Dashboard EPA DTXSID10290591 InChI InChI 1S C5H4N4O4 c10 2 5 13 1 6 3 11 8 2 7 4 12 9 5 h13H H3 6 7 8 9 10 11 12 YKey LTQYPAVLAYVKTK UHFFFAOYSA N YInChI 1 C5H4N4O4 c10 2 5 13 1 6 3 11 8 2 7 4 12 9 5 h13H H3 6 7 8 9 10 11 12 Key LTQYPAVLAYVKTK UHFFFAOYAS SMILES C12 NC O NC1 C O NC O N2 OO C1NC O N C2 N C O NC12O Properties Chemical formula C5H4N4O4 Molar mass 184 11 g mol Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa N verify what is Y N Infobox references sequence of oxidation of ureate 5 Hydroxyisourate rearranges to allantoin References edit Oksanen E Blakeley MP El Hajji M Ryde U Budayova Spano M 2014 01 23 The Neutron Structure of Urate Oxidase Resolves a Long Standing Mechanistic Conundrum and Reveals Unexpected Changes in Protonation PLOS ONE 9 1 e86651 Bibcode 2014PLoSO 986651O doi 10 1371 journal pone 0086651 PMC 3900588 PMID 24466188 Fetzner Susanne Steiner Roberto A 2010 Cofactor independent oxidases and oxygenases Applied Microbiology and Biotechnology 86 3 791 804 doi 10 1007 s00253 010 2455 0 PMID 20157809 S2CID 25377247 See also editUrate oxidase Glycolaldehyde nbsp This article about an organic compound is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 5 Hydroxyisourate amp oldid 1145336645, wikipedia, wiki, book, books, library,

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