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Wikipedia

Oxaline

Oxaline is a fungal isolate with anticancer activity in vitro.[1] It is an O-methylated derivative of meleagrin.

Oxaline
Identifiers
  • 55623-37-5 N
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:70400
ChemSpider
  • 10225680
  • 6438440
  • DTXSID60893990
  • InChI=1S/C24H25N5O4/c1-6-22(2,3)23-12-19(32-4)21(31)28-18(11-15-13-25-14-26-15)20(30)27-24(23,28)29(33-5)17-10-8-7-9-16(17)23/h6-14H,1H2,2-5H3,(H,25,26)(H,27,30)/b18-11+/t23-,24-/m1/s1
    Key: SOHAVULMGIITDH-SSDCDQDPSA-N
  • InChI=1/C24H25N5O4/c1-6-22(2,3)23-12-19(32-4)21(31)28-18(11-15-13-25-14-26-15)20(30)27-24(23,28)29(33-5)17-10-8-7-9-16(17)23/h6-14H,1H2,2-5H3,(H,25,26)(H,27,30)/b18-11+/t23-,24-/m1/s1
    Key: SOHAVULMGIITDH-SSDCDQDPBU
  • CC(C)(C=C)[C@]12C=C(C(=O)N\3[C@@]1(NC(=O)/C3=C\c4c[nH]cn4)N(c5c2cccc5)OC)OC
Properties
C24H25N5O4
Molar mass 447.495 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References edit

  1. ^ Koizumi, Y; Arai, M; Tomoda, H; Omura, S (2004). "Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1693 (1): 47–55. doi:10.1016/j.bbamcr.2004.04.013. PMID 15276324.


oxaline, short, glyoxaline, imidazole, fungal, isolate, with, anticancer, activity, vitro, methylated, derivative, meleagrin, identifiers, number, 55623, model, jsmol, interactive, image, chebi, chebi, 70400, chemspider, 10225680, pubchem, 6438440, comptox, da. For the short for glyoxaline see Imidazole Oxaline is a fungal isolate with anticancer activity in vitro 1 It is an O methylated derivative of meleagrin Oxaline Identifiers CAS Number 55623 37 5 N 3D model JSmol Interactive image ChEBI CHEBI 70400 ChemSpider 10225680 PubChem CID 6438440 CompTox Dashboard EPA DTXSID60893990 InChI InChI 1S C24H25N5O4 c1 6 22 2 3 23 12 19 32 4 21 31 28 18 11 15 13 25 14 26 15 20 30 27 24 23 28 29 33 5 17 10 8 7 9 16 17 23 h6 14H 1H2 2 5H3 H 25 26 H 27 30 b18 11 t23 24 m1 s1Key SOHAVULMGIITDH SSDCDQDPSA NInChI 1 C24H25N5O4 c1 6 22 2 3 23 12 19 32 4 21 31 28 18 11 15 13 25 14 26 15 20 30 27 24 23 28 29 33 5 17 10 8 7 9 16 17 23 h6 14H 1H2 2 5H3 H 25 26 H 27 30 b18 11 t23 24 m1 s1Key SOHAVULMGIITDH SSDCDQDPBU SMILES CC C C C C 12C C C O N 3 C 1 NC O C3 C c4c nH cn4 N c5c2cccc5 OC OC Properties Chemical formula C 24H 25N 5O 4 Molar mass 447 495 g mol 1 Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Infobox referencesReferences edit Koizumi Y Arai M Tomoda H Omura S 2004 Oxaline a fungal alkaloid arrests the cell cycle in M phase by inhibition of tubulin polymerization Biochimica et Biophysica Acta BBA Molecular Cell Research 1693 1 47 55 doi 10 1016 j bbamcr 2004 04 013 PMID 15276324 nbsp This article about an alkaloid is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Oxaline amp oldid 1143954709, wikipedia, wiki, book, books, library,

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