^Ghorani-Azam A, Balali-Mood M (2015). "Clinical pharmacology and toxicology of mustard compounds.". In Balali-Mood M, Abdollahi M (eds.). Basic and clinical toxicology of mustard compounds. Cham: Springer. p. 74. ISBN978-3-319-23874-6.
uramustine, uracil, mustard, chemotherapy, drug, which, belongs, class, alkylating, agents, used, lymphatic, malignancies, such, hodgkin, lymphoma, works, damaging, primarily, cancer, cells, that, preferentially, take, uracil, their, need, make, nucleic, acids. Uramustine INN or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents 1 It is used in lymphatic malignancies such as non Hodgkin s lymphoma It works by damaging DNA primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division The DNA damage leads to apoptosis of the affected cells Bone marrow suppression and nausea are the main side effects UramustineClinical dataATC codeL01AD08 WHO Pharmacokinetic dataProtein binding5 ExcretionRenalIdentifiersIUPAC name 5 bis 2 Chloroethyl amino 1H pyrimidine 2 4 dioneCAS Number66 75 1 YPubChem CID6194IUPHAR BPS7621DrugBankDB00791 NChemSpider5959 NUNIIW7KQ46GJ8UKEGGD06265 YChEMBLChEMBL1488 NCompTox Dashboard EPA DTXSID8026270ECHA InfoCard100 000 574Chemical and physical dataFormulaC 8H 11Cl 2N 3O 2Molar mass252 10 g mol 13D model JSmol Interactive imageSMILES O C1C N CCCl CCCl C NC O N1InChI InChI 1S C8H11Cl2N3O2 c9 1 3 13 4 2 10 6 5 11 8 15 12 7 6 14 h5H 1 4H2 H2 11 12 14 15 NKey IDPUKCWIGUEADI UHFFFAOYSA N N N Y what is this verify Chemically it is a derivative of nitrogen mustard and uracil References edit Ghorani Azam A Balali Mood M 2015 Clinical pharmacology and toxicology of mustard compounds In Balali Mood M Abdollahi M eds Basic and clinical toxicology of mustard compounds Cham Springer p 74 ISBN 978 3 319 23874 6 nbsp This antineoplastic or immunomodulatory drug article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Uramustine amp oldid 1147749686, wikipedia, wiki, book, books, library,
