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Tryptophan tryptophylquinone

Tryptophan tryptophylquinone (TTQ)[1] is an enzyme cofactor, generated by posttranslational modification of amino acids within the protein. Methylamine dehydrogenase (MADH), an amine dehydrogenase, requires TTQ for its catalytic function.[2]

Tryptophan tryptophylquinone
Names
IUPAC name
2-Amino-3-[2-[2-amino-3-(2-carboxyethyl)-6,7-dioxo-1H-indol-4-yl]-1H-indol-3-yl]propanoic acid
Identifiers
  • 134645-25-3 Y
3D model (JSmol)
  • Interactive image
MeSH Tryptophan+tryptophylquinone
  • 5486829
  • C1=CC=C2C(=C1)C(=C(N2)C3=CC(=O)C(=O)C4=C3C(=C(N4)N)CCC(=O)O)CC(C(=O)O)N
Properties
C22H20N4O6
Molar mass 436.424 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)

See also edit

References edit

  1. ^ Davidson, V. L.; Liu, A. (2012). "Tryptophan tryptophylquinone biosynthesis: A radical approach to posttranslational modification, by Victor L. Davidson1 and Aimin Liu2, on National Center for Biotechnology Information, U.S. National Library of Medicine, published 2012 Jan 28. doi: 10.1016/j.bbapap.2012.01.008". Biochimica et Biophysica Acta. 1824 (11): 1299–1305. doi:10.1016/j.bbapap.2012.01.008. PMC 3432176. PMID 22314272.
  2. ^ Davidson VL, Liu A (2009). "Uncovering novel biochemistry in the mechanism of tryptophan tryptophylquinone cofactor biosynthesis". Curr. Opin. Chem. Biol. 13 (4): 469–474. doi:10.1016/j.cbpa.2009.06.026. PMC 2749888. PMID 19648051.

tryptophan, tryptophylquinone, enzyme, cofactor, generated, posttranslational, modification, amino, acids, within, protein, methylamine, dehydrogenase, madh, amine, dehydrogenase, requires, catalytic, function, namesiupac, name, amino, amino, carboxyethyl, dio. Tryptophan tryptophylquinone TTQ 1 is an enzyme cofactor generated by posttranslational modification of amino acids within the protein Methylamine dehydrogenase MADH an amine dehydrogenase requires TTQ for its catalytic function 2 Tryptophan tryptophylquinone NamesIUPAC name 2 Amino 3 2 2 amino 3 2 carboxyethyl 6 7 dioxo 1H indol 4 yl 1H indol 3 yl propanoic acidIdentifiersCAS Number 134645 25 3 Y3D model JSmol Interactive imageMeSH Tryptophan tryptophylquinonePubChem CID 5486829SMILES C1 CC C2C C1 C C N2 C3 CC O C O C4 C3C C N4 N CCC O O CC C O O NPropertiesChemical formula C 22H 20N 4O 6Molar mass 436 424 g mol 1Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Y verify what is Y N Infobox referencesSee also editAmicyaninReferences edit Davidson V L Liu A 2012 Tryptophan tryptophylquinone biosynthesis A radical approach to posttranslational modification by Victor L Davidson1 and Aimin Liu2 on National Center for Biotechnology Information U S National Library of Medicine published 2012 Jan 28 doi 10 1016 j bbapap 2012 01 008 Biochimica et Biophysica Acta 1824 11 1299 1305 doi 10 1016 j bbapap 2012 01 008 PMC 3432176 PMID 22314272 Davidson VL Liu A 2009 Uncovering novel biochemistry in the mechanism of tryptophan tryptophylquinone cofactor biosynthesis Curr Opin Chem Biol 13 4 469 474 doi 10 1016 j cbpa 2009 06 026 PMC 2749888 PMID 19648051 nbsp This biochemistry article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Tryptophan tryptophylquinone amp oldid 1178544111, wikipedia, wiki, book, books, library,

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