Tricetin is a flavone, a type of flavonoid. It is a rare aglycone found in the pollen of members of the Myrtaceae, subfamily Leptospermoideae, such as Eucalyptus globulus.[1] This compound shows anticancer effects on human breast adenocarcinoma MCF-7 cells.[2] Moreover. a potent anti-inflammatory effect of tricetin has also been demonstrated in a model of acute pancreatitis.[3] This observation was explained by the compound's radical scavenging effects, its inhibitory effect on the DNA damage sensor enzyme poly (ADP-ribose) polymerase-1 (PARP1) and PARP1-mediated cell death and suppression of inflammatory gene expression.
^Campos, Maria G.; Webby, Rosemary F.; Markham, Kenneth R. (2002). "The unique occurrence of the flavone aglycone tricetin in Myrtaceae pollen". Zeitschrift für Naturforschung C. 57 (9–10): 944–946. doi:10.1515/znc-2002-9-1031. PMID 12440738. S2CID29128828.
^Hsu, Ya-Ling; Uen, Yih-Huei; Chen, Yi; Liang, Hsin-Lin; Kuo, Po-Lin (2009). "Tricetin, a dietary flavonoid, inhibits proliferation of human breast adenocarcinoma MCF-7 cells by blocking cell cycle progression and inducing apoptosis". Journal of Agricultural and Food Chemistry. 57 (18): 8688–8695. doi:10.1021/jf901053x. PMID 19705844. S2CID 19856762.
^Nagy-Pénzes, Máté; Hajnády, Zoltán; Regdon, Zsolt; Demény, Máté Á; Kovács, Katalin; El-Hamoly, Tarek; Maléth, József; Hegyi, Péter; Hegedűs, Csaba; Virág, László (June 2022). "Tricetin Reduces Inflammation and Acinar Cell Injury in Cerulein-Induced Acute Pancreatitis: The Role of Oxidative Stress-Induced DNA Damage Signaling". Biomedicines. 10 (6): 1371. doi:10.3390/biomedicines10061371. ISSN 2227-9059. PMC9219693. PMID 35740393.
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tricetin, flavone, type, flavonoid, rare, aglycone, found, pollen, members, myrtaceae, subfamily, leptospermoideae, such, eucalyptus, globulus, this, compound, shows, anticancer, effects, human, breast, adenocarcinoma, cells, moreover, potent, anti, inflammato. Tricetin is a flavone a type of flavonoid It is a rare aglycone found in the pollen of members of the Myrtaceae subfamily Leptospermoideae such as Eucalyptus globulus 1 This compound shows anticancer effects on human breast adenocarcinoma MCF 7 cells 2 Moreover a potent anti inflammatory effect of tricetin has also been demonstrated in a model of acute pancreatitis 3 This observation was explained by the compound s radical scavenging effects its inhibitory effect on the DNA damage sensor enzyme poly ADP ribose polymerase 1 PARP1 and PARP1 mediated cell death and suppression of inflammatory gene expression Tricetin NamesPreferred IUPAC name 5 7 Dihydroxy 2 3 4 5 trihydroxyphenyl 4H 1 benzopyran 4 oneOther names 3 4 5 5 7 PentahydroxyflavoneIdentifiersCAS Number 520 31 0 Y3D model JSmol Interactive imageChemSpider 4445018ECHA InfoCard 100 237 320PubChem CID 5281701UNII 5627PY99ZO YCompTox Dashboard EPA DTXSID60199964InChI InChI 1S C15H10O7 c16 7 3 8 17 14 9 18 5 12 22 13 14 4 7 6 1 10 19 15 21 11 20 2 6 h1 5 16 17 19 21HKey ARSRJFRKVXALTF UHFFFAOYSA NSMILES C1 C C C C C1O O O C2 CC O C3 C C C C C3O2 O OPropertiesChemical formula C15H10O7Molar mass 302 23 g molExcept where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Infobox referencesSee also EditTricin synthase produces tricin or tricetin 3 5 dimethyl ether Tricetin 3 4 5 O trimethyltransferaseReferences Edit Campos Maria G Webby Rosemary F Markham Kenneth R 2002 The unique occurrence of the flavone aglycone tricetin in Myrtaceae pollen Zeitschrift fur Naturforschung C 57 9 10 944 946 doi 10 1515 znc 2002 9 1031 PMID 12440738 S2CID 29128828 Hsu Ya Ling Uen Yih Huei Chen Yi Liang Hsin Lin Kuo Po Lin 2009 Tricetin a dietary flavonoid inhibits proliferation of human breast adenocarcinoma MCF 7 cells by blocking cell cycle progression and inducing apoptosis Journal of Agricultural and Food Chemistry 57 18 8688 8695 doi 10 1021 jf901053x PMID 19705844 S2CID 19856762 Nagy Penzes Mate Hajnady Zoltan Regdon Zsolt Demeny Mate A Kovacs Katalin El Hamoly Tarek Maleth Jozsef Hegyi Peter Hegedus Csaba Virag Laszlo June 2022 Tricetin Reduces Inflammation and Acinar Cell Injury in Cerulein Induced Acute Pancreatitis The Role of Oxidative Stress Induced DNA Damage Signaling Biomedicines 10 6 1371 doi 10 3390 biomedicines10061371 ISSN 2227 9059 PMC 9219693 PMID 35740393 This article about an aromatic compound is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Tricetin amp oldid 1118289088, wikipedia, wiki, book, books, library,
