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Wikipedia

TUBGCP3

Gamma-tubulin complex component 3 is a protein that in humans is encoded by the TUBGCP3 gene.[5][6][7] It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

TUBGCP3
Identifiers
AliasesTUBGCP3, 104p, GCP3, Grip104, SPBC98, Spc98, Spc98p, tubulin gamma complex associated protein 3, ALP6
External IDsOMIM: 617818 MGI: 2183752 HomoloGene: 4609 GeneCards: TUBGCP3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001286277
NM_001286278
NM_001286279
NM_006322

NM_198031

RefSeq (protein)

NP_001273206
NP_001273207
NP_001273208
NP_006313

NP_932148

Location (UCSC)Chr 13: 112.49 – 112.59 MbChr 8: 12.66 – 12.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

See also edit

References edit

  1. ^ a b c ENSG00000126216 GRCh38: Ensembl release 89: ENSG00000282003, ENSG00000126216 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000759 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Murphy SM, Urbani L, Stearns T (Jun 1998). "The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p". J Cell Biol. 141 (3): 663–74. doi:10.1083/jcb.141.3.663. PMC 2132743. PMID 9566967.
  6. ^ Tassin AM, Celati C, Moudjou M, Bornens M (Jun 1998). "Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin". J Cell Biol. 141 (3): 689–701. doi:10.1083/jcb.141.3.689. PMC 2132749. PMID 9566969.
  7. ^ "Entrez Gene: TUBGCP3 tubulin, gamma complex associated protein 3".

Further reading edit

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. Bibcode:2004Natur.428..522D. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Takahashi M, Yamagiwa A, Nishimura T, et al. (2003). "Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex". Mol. Biol. Cell. 13 (9): 3235–45. doi:10.1091/mbc.E02-02-0112. PMC 124155. PMID 12221128.
  • Murphy SM, Preble AM, Patel UK, et al. (2002). "GCP5 and GCP6: two new members of the human gamma-tubulin complex". Mol. Biol. Cell. 12 (11): 3340–52. doi:10.1091/mbc.12.11.3340. PMC 60259. PMID 11694571.


tubgcp3, gamma, tubulin, complex, component, protein, that, humans, encoded, gene, part, gamma, tubulin, complex, which, required, microtubule, nucleation, centrosome, identifiersaliases, 104p, gcp3, grip104, spbc98, spc98, spc98p, tubulin, gamma, complex, ass. Gamma tubulin complex component 3 is a protein that in humans is encoded by the TUBGCP3 gene 5 6 7 It is part of the gamma tubulin complex which required for microtubule nucleation at the centrosome TUBGCP3IdentifiersAliasesTUBGCP3 104p GCP3 Grip104 SPBC98 Spc98 Spc98p tubulin gamma complex associated protein 3 ALP6External IDsOMIM 617818 MGI 2183752 HomoloGene 4609 GeneCards TUBGCP3Gene location Human Chr Chromosome 13 human 1 Band13q34Start112 485 011 bp 1 End112 588 205 bp 1 Gene location Mouse Chr Chromosome 8 mouse 2 Band8 8 A1 1Start12 664 277 bp 2 End12 722 248 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inmonocytebone marrow cellsganglionic eminencegastric mucosatibial nerveright lobe of liverskin of abdomenappendixcanal of the cervixleft uterine tubeTop expressed inthymuscerebellar cortexsuperior frontal gyrusdorsomedial hypothalamic nucleusdermisneural tubemedullary collecting ductganglionic eminenceyolk sacventromedial nucleusMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionstructural molecule activity structural constituent of cytoskeleton protein binding microtubule minus end binding gamma tubulin bindingCellular componentcytoplasm cytosol centrosome spindle pole equatorial microtubule organizing center membrane spindle microtubule organizing center gamma tubulin small complex polar microtubule spindle pole body centriole cytoskeleton microtubule gamma tubulin complexBiological processcentrosome duplication microtubule nucleation by interphase microtubule organizing center single fertilization mitotic spindle assembly cytoplasmic microtubule organization microtubule cytoskeleton organization microtubule nucleation meiosis mitotic cell cycle spindle assemblySources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez10426259279EnsemblENSG00000282003ENSG00000126216ENSMUSG00000000759UniProtQ96CW5P58854RefSeq mRNA NM 001286277NM 001286278NM 001286279NM 006322NM 198031RefSeq protein NP 001273206NP 001273207NP 001273208NP 006313NP 932148Location UCSC Chr 13 112 49 112 59 MbChr 8 12 66 12 72 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseSee also editTubulin TUBGCP2 TUBGCP4 TUBGCP5 TUBGCP6References edit a b c ENSG00000126216 GRCh38 Ensembl release 89 ENSG00000282003 ENSG00000126216 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000000759 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Murphy SM Urbani L Stearns T Jun 1998 The mammalian gamma tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p J Cell Biol 141 3 663 74 doi 10 1083 jcb 141 3 663 PMC 2132743 PMID 9566967 Tassin AM Celati C Moudjou M Bornens M Jun 1998 Characterization of the human homologue of the yeast spc98p and its association with gamma tubulin J Cell Biol 141 3 689 701 doi 10 1083 jcb 141 3 689 PMC 2132749 PMID 9566969 Entrez Gene TUBGCP3 tubulin gamma complex associated protein 3 Further reading editRual JF Venkatesan K Hao T et al 2005 Towards a proteome scale map of the human protein protein interaction network Nature 437 7062 1173 8 Bibcode 2005Natur 437 1173R doi 10 1038 nature04209 PMID 16189514 S2CID 4427026 Gerhard DS Wagner L Feingold EA et al 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Dunham A Matthews LH Burton J et al 2004 The DNA sequence and analysis of human chromosome 13 Nature 428 6982 522 8 Bibcode 2004Natur 428 522D doi 10 1038 nature02379 PMC 2665288 PMID 15057823 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Takahashi M Yamagiwa A Nishimura T et al 2003 Centrosomal proteins CG NAP and kendrin provide microtubule nucleation sites by anchoring gamma tubulin ring complex Mol Biol Cell 13 9 3235 45 doi 10 1091 mbc E02 02 0112 PMC 124155 PMID 12221128 Murphy SM Preble AM Patel UK et al 2002 GCP5 and GCP6 two new members of the human gamma tubulin complex Mol Biol Cell 12 11 3340 52 doi 10 1091 mbc 12 11 3340 PMC 60259 PMID 11694571 nbsp This article on a gene on human chromosome 13 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title TUBGCP3 amp oldid 1142727510, wikipedia, wiki, book, books, library,

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