fbpx
Wikipedia

Satoshi Ōmura

Satoshi Ōmura (大村 智, Ōmura Satoshi, [oːmɯɾa saꜜtoɕi]; born 12 July 1935) is a Japanese biochemist. He is known for the discovery and development of hundreds of pharmaceuticals originally occurring in microorganisms. In 2015, he was awarded the Nobel Prize in Physiology or Medicine jointly with William C. Campbell for their role in the discovery of avermectins and ivermectin,[1] the world's first endectocide and a safe and highly effective microfilaricide.[2] It is believed that the large molecular size of ivermectin prevents it from crossing the blood/aqueous humour barrier, and renders the drug an important treatment of helminthically-derived blindness.

Satoshi Ōmura
大村 智
Satoshi Ōmura, Nobel Laureate in medicine in Stockholm December 2015
Born (1935-07-12) 12 July 1935 (age 87)
NationalityJapanese
Alma materUniversity of Yamanashi (B.S.
Tokyo University of Science (M.S., Sc. D.)
University of Tokyo (Ph. D.)
Known forAvermectin and Ivermectin
Discovery of more than 480 new compounds
AwardsJapan Academy Prize (1990)
Koch Gold Medal (1997)
Ernest Guenther Award in the Chemistry of Natural Products (2005)
Tetrahedron Prize for Creativity in Organic Chemistry (2010)
Gairdner Global Health Award (2014)
Nobel Prize in Physiology or Medicine (2015)
Scientific career
FieldsBiochemistry
InstitutionsKitasato University
Wesleyan University
Academic advisorsKoji Nakanishi
Max Tishler

Early life and education

Satoshi Ōmura was born in Nirasaki, Yamanashi Japan in 1935, the second son of Ōmura family. After graduating from the University of Yamanashi in 1958, he was appointed to science teacher at Tokyo Metropolitan Sumida Tech High School. In 1960, he became an auditor of Koji Nakanishi’s course at Tokyo University of Education, one year later, he enrolled in the Tokyo University of Science (TUS) and studied sciences. Ōmura received his M.S. degree from TUS and his Ph.D. in Pharmaceutical Sciences from the University of Tokyo (1968, a Dissertation PhD) and a Ph.D. in Chemistry at TUS (1970).[3]

Career

Since 1965 Ōmura served at Kitasato Institute system.[4] From 1970 to 1990, he also became a part-time lecturer at Tokyo University of Science.[5]

In 1971 while he was a visiting professor at Wesleyan University,[4] he consulted the chairman of the American Chemical Society, Max Tishler, at an international conference. Together they successfully acquired research expenses from Merck & Co.[6] Ōmura was considering continuing his research in the United States, but ultimately he decided to return to Japan.

In 1973, he became a director of the antibiotic laboratory at Kitasato University,[7] and he also started collaborative research with Merck & Co.[8]

In 1975, he became professor of Kitasato University School of Pharmacy. Meanwhile, the Ōmura laboratory raised many researchers and produced 31 university professors and 120 doctors.

At present date, Ōmura is professor emeritus at Kitasato University and Max Tishler Professor of Chemistry at Wesleyan University.

Research

 
A molecular diagram of Ivermectin, one of Omura's discoveries

Satoshi Ōmura is known for the discovery and development of various pharmaceuticals originally occurring in microorganisms. He was awarded the 2015 Nobel Prize in Physiology or Medicine jointly with William C. Campbell and Tu Youyou for discoveries concerning a novel therapy against infections caused by roundworm parasites. More precisely, his research group isolated a strain of Streptomyces avermitilis that produce the anti-parasitical compound avermectin.[2] Campbell later acquired these bacteria and developed the derived drug ivermectin that was first commercialised for veterinary use in 1981 later put to human use against Onchocerciasis in 1987–88 with the name Mectizan,[2] and is today used against river blindness, lymphatic filariasis, scabies and other parasitic infections.[3][9][10]

Since the 1970s, Ōmura has discovered more than 480 new compounds, of which 25 kinds of drugs and reagents are in use. Examples include andrastin, herbimycin, neoxaline as well as:

Furthermore, compounds having a unique structure and biological activity discovered by Omura are drawing attention in drug discovery research, and new anticancer drugs and the like have been created.

Selected publications

  • Satoshi Ōmura; Y Iwai; A Hirano; A Nakagawa; J Awaya; H Tsuchya; Y Takahashi; R Masuma (April 1977). "A new alkaloid AM-2282 OF Streptomyces origin. Taxonomy, fermentation, isolation and preliminary characterization". The Journal of Antibiotics. 30 (4): 275–82. doi:10.7164/ANTIBIOTICS.30.275. ISSN 0021-8820. PMID 863788. Wikidata Q28279608.
  • R W Burg; B M Miller; E E Baker; et al. (March 1979). "Avermectins, new family of potent anthelmintic agents: producing organism and fermentation". Antimicrobial Agents and Chemotherapy. 15 (3): 361–7. doi:10.1128/AAC.15.3.361. ISSN 0066-4804. PMC 352666. PMID 464561. Wikidata Q24598202.
  • D A Hopwood; F Malpartida; H M Kieser; et al. (1 April 1985). "Production of 'hybrid' antibiotics by genetic engineering". Nature. 314 (6012): 642–644. doi:10.1038/314642A0. ISSN 1476-4687. PMID 3857464. Wikidata Q59071761.
  • H Ikeda; T Nonomiya; M Usami; T Ohta; Satoshi Ōmura (1 August 1999). "Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis". Proceedings of the National Academy of Sciences of the United States of America. 96 (17): 9509–9514. Bibcode:1999PNAS...96.9509I. doi:10.1073/PNAS.96.17.9509. ISSN 0027-8424. PMC 22239. PMID 10449723. Wikidata Q33871234.
  • Masahiko Hayashi; Mun-Chual Rho; Akiko Enomoto; et al. (4 November 2002). "Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130". Proceedings of the National Academy of Sciences of the United States of America. 99 (23): 14728–14733. Bibcode:2002PNAS...9914728H. doi:10.1073/PNAS.232562799. ISSN 0027-8424. PMC 137487. PMID 12417753. Wikidata Q34379185.
  • Tomoyasu Hirose; Toshiaki Sunazuka; Satoshi Omura (1 January 2010). "Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms". Proceedings of the Japan Academy, Series B. 86 (2): 85–102. doi:10.2183/PJAB.86.85. ISSN 0386-2208. PMC 3417560. PMID 20154467. Wikidata Q34098670.
  • Nobuyuki Matoba; Adam S Husk; Brian W Barnett; et al. (2010). "HIV-1 neutralization profile and plant-based recombinant expression of actinohivin, an Env glycan-specific lectin devoid of T-cell mitogenic activity". PLOS One. 5 (6): e11143. Bibcode:2010PLoSO...511143M. doi:10.1371/JOURNAL.PONE.0011143. ISSN 1932-6203. PMC 2886112. PMID 20559567. Wikidata Q21076115.
  • Hirofumi Nakano; Satoshi Omura (9 January 2009). "Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine". The Journal of Antibiotics. 62 (1): 17–26. doi:10.1038/JA.2008.4. ISSN 0021-8820. PMID 19132059. Wikidata Q34918248.
  • Ōmura, S. (2011). "Microbial metabolites: 45 years of wandering, wondering and discovering". Tetrahedron. 67 (35): 6420–6459. doi:10.1016/j.tet.2011.03.117.

Social role

Ōmura served as deputy director and director at the Kitasato Institute. He was devoted to rebuild the laboratory and promoting the establishment of the medical center that is now Kitasato University Medical Center. Meanwhile, he established a path to rebuilding of the corporate school juridical person, which has integrated with the School corporation Kitasato Gakuen. He succeeded in establishing a new "School corporation Kitasato Institute". In addition, he served as president of the School corporation Joshibi University of Art and Design twice, and served as the honorary school chief of the School corporation Kaichi Gakuen.[11] In 2007, he established the Nirasaki Omura Art Museum on his collection.[12]

Awards and honors

 
Satoshi Ōmura (left) and William C. Campbell (right) in Stockholm, December 2015.

A Children's statues leading to adults of onchocerciasis before Kitasato University buildings were produced by sculptors of Burkina Faso in honor of Ōmura's contributions of avermectin and ivermectin, a symbol of the campaign to eradicate onchocerciasis.[clarification needed][13] Similar life-sized bronze statues were erected in World Health Organization (WHO) Headquarters,[where?] Carter Center, Merck & Co., World Bank Headquarters, and Burkina Faso's World Health Organization Africa Onchocerciasis Control Program.[clarification needed]

Honorary doctorates

List of honorary doctorates:[18]

Learned societies membership

See also

References

  1. ^ "The Nobel Prize in Physiology or Medicine 2015". Nobel Prize Outreach AB. 6 October 2015.
  2. ^ a b c Andy Crump; Satoshi Ōmura (1 January 2011). "Ivermectin, 'wonder drug' from Japan: the human use perspective". Proceedings of the Japan Academy, Series B. 87 (2): 13–28. Bibcode:2011PJAB...87...13C. doi:10.2183/PJAB.87.13. ISSN 0386-2208. PMC 3043740. PMID 21321478. Wikidata Q34598257.
  3. ^ a b "Satoshi Omura PhD". Retrieved 5 October 2015.
  4. ^ a b 大村智北里研究所顧問・北里大学名誉教授が文化功労者に 北里大学 2012年11月1日
  5. ^ [from ストックホルム]「これからは人材の育成に努力します」大村先生が語った受賞後の活動 TUSToday 2015.12.18
  6. ^ 「人間発見」日本経済新聞2010年7月14日
  7. ^ 「【ノーベル賞受賞】大村智氏、常識破りの発想で治療薬開発 」 産経ニュース2015.10.5
  8. ^ 「 新しい微生物創薬の世界を切り開く 」 JT
  9. ^ Press release NobelPrize.org
  10. ^ "Japanese microbiologist Satoshi Omura shares Nobel Prize for medicine". The Japan Times. 5 October 2015. Retrieved 5 October 2015.
  11. ^ "大村先生". 開智学園高等部. Retrieved 2015-10-12.
  12. ^ . 韮崎大村美術館. Archived from the original on 2015-10-15. Retrieved 2015-10-12.
  13. ^ "『新しい微生物創薬の世界を切り開く』大村 智". サイエンティスト・ライブラリー | JT生命誌研究館. Retrieved 14 March 2022.
  14. ^ a b c d e f g h i j k l m n o Satoshi Ōmura. "Satoshi Ōmura Curriculum Vitae" (PDF).
  15. ^ "Robert Koch Gold Medal". Robert-Koch-Stiftung e.V. Retrieved 2015-10-05.
  16. ^ 【政府】11年「春の叙勲」‐森田氏に旭重、大村氏が瑞重 薬事日報 2011年6月20日
  17. ^ "Satoshi Ōmura". Retrieved 14 March 2022.
  18. ^ http://www.satoshi-omura.info/biography/omura_cv.pdf[bare URL PDF]
  19. ^ "List of Members | Prof. Dr. Dr. Satoshi Ōmura". Retrieved 14 March 2022.
  20. ^ "Satoshi Omura". www.nasonline.org. Retrieved 14 March 2022.
  21. ^ "Personal Information – ŌMURA Satoshi | The Japan Academy". www.japan-acad.go.jp. Retrieved 14 March 2022.
  22. ^ "Satoshi Omura | Liste des membres de l'Académie des sciences / O | Listes par ordre alphabétique | Listes des membres | Membres | Nous connaître". www.academie-sciences.fr. Retrieved 14 March 2022.

External links

  • Professor Satoshi Omura
  • Satoshi Ōmura | People | THE KITASATO INSTITUTE
  • Nirasaki Omura Art Museum
  • Satoshi Ōmura Quotes With Pictures
  • Satoshi Ōmura on Nobelprize.org  

satoshi, Ōmura, 大村, Ōmura, satoshi, oːmɯɾa, saꜜtoɕi, born, july, 1935, japanese, biochemist, known, discovery, development, hundreds, pharmaceuticals, originally, occurring, microorganisms, 2015, awarded, nobel, prize, physiology, medicine, jointly, with, will. Satoshi Ōmura 大村 智 Ōmura Satoshi oːmɯɾa saꜜtoɕi born 12 July 1935 is a Japanese biochemist He is known for the discovery and development of hundreds of pharmaceuticals originally occurring in microorganisms In 2015 he was awarded the Nobel Prize in Physiology or Medicine jointly with William C Campbell for their role in the discovery of avermectins and ivermectin 1 the world s first endectocide and a safe and highly effective microfilaricide 2 It is believed that the large molecular size of ivermectin prevents it from crossing the blood aqueous humour barrier and renders the drug an important treatment of helminthically derived blindness Satoshi Ōmura大村 智Satoshi Ōmura Nobel Laureate in medicine in Stockholm December 2015Born 1935 07 12 12 July 1935 age 87 Nirasaki Yamanashi JapanNationalityJapaneseAlma materUniversity of Yamanashi B S Tokyo University of Science M S Sc D University of Tokyo Ph D Known forAvermectin and IvermectinDiscovery of more than 480 new compoundsAwardsJapan Academy Prize 1990 Koch Gold Medal 1997 Ernest Guenther Award in the Chemistry of Natural Products 2005 Tetrahedron Prize for Creativity in Organic Chemistry 2010 Gairdner Global Health Award 2014 Nobel Prize in Physiology or Medicine 2015 Scientific careerFieldsBiochemistryInstitutionsKitasato UniversityWesleyan UniversityAcademic advisorsKoji NakanishiMax Tishler Contents 1 Early life and education 2 Career 3 Research 3 1 Selected publications 4 Social role 5 Awards and honors 5 1 Honorary doctorates 6 Learned societies membership 7 See also 8 References 9 External linksEarly life and education EditSatoshi Ōmura was born in Nirasaki Yamanashi Japan in 1935 the second son of Ōmura family After graduating from the University of Yamanashi in 1958 he was appointed to science teacher at Tokyo Metropolitan Sumida Tech High School In 1960 he became an auditor of Koji Nakanishi s course at Tokyo University of Education one year later he enrolled in the Tokyo University of Science TUS and studied sciences Ōmura received his M S degree from TUS and his Ph D in Pharmaceutical Sciences from the University of Tokyo 1968 a Dissertation PhD and a Ph D in Chemistry at TUS 1970 3 Career EditSince 1965 Ōmura served at Kitasato Institute system 4 From 1970 to 1990 he also became a part time lecturer at Tokyo University of Science 5 In 1971 while he was a visiting professor at Wesleyan University 4 he consulted the chairman of the American Chemical Society Max Tishler at an international conference Together they successfully acquired research expenses from Merck amp Co 6 Ōmura was considering continuing his research in the United States but ultimately he decided to return to Japan In 1973 he became a director of the antibiotic laboratory at Kitasato University 7 and he also started collaborative research with Merck amp Co 8 In 1975 he became professor of Kitasato University School of Pharmacy Meanwhile the Ōmura laboratory raised many researchers and produced 31 university professors and 120 doctors At present date Ōmura is professor emeritus at Kitasato University and Max Tishler Professor of Chemistry at Wesleyan University Research Edit A molecular diagram of Ivermectin one of Omura s discoveries Satoshi Ōmura is known for the discovery and development of various pharmaceuticals originally occurring in microorganisms He was awarded the 2015 Nobel Prize in Physiology or Medicine jointly with William C Campbell and Tu Youyou for discoveries concerning a novel therapy against infections caused by roundworm parasites More precisely his research group isolated a strain of Streptomyces avermitilis that produce the anti parasitical compound avermectin 2 Campbell later acquired these bacteria and developed the derived drug ivermectin that was first commercialised for veterinary use in 1981 later put to human use against Onchocerciasis in 1987 88 with the name Mectizan 2 and is today used against river blindness lymphatic filariasis scabies and other parasitic infections 3 9 10 Since the 1970s Ōmura has discovered more than 480 new compounds of which 25 kinds of drugs and reagents are in use Examples include andrastin herbimycin neoxaline as well as a specific inhibitor of protein kinase named staurosporine a proteasome inhibitor named lactacystin a fatty acid biosynthesis inhibitor named cerulenin Furthermore compounds having a unique structure and biological activity discovered by Omura are drawing attention in drug discovery research and new anticancer drugs and the like have been created Selected publications Edit Satoshi Ōmura Y Iwai A Hirano A Nakagawa J Awaya H Tsuchya Y Takahashi R Masuma April 1977 A new alkaloid AM 2282 OF Streptomyces origin Taxonomy fermentation isolation and preliminary characterization The Journal of Antibiotics 30 4 275 82 doi 10 7164 ANTIBIOTICS 30 275 ISSN 0021 8820 PMID 863788 Wikidata Q28279608 R W Burg B M Miller E E Baker et al March 1979 Avermectins new family of potent anthelmintic agents producing organism and fermentation Antimicrobial Agents and Chemotherapy 15 3 361 7 doi 10 1128 AAC 15 3 361 ISSN 0066 4804 PMC 352666 PMID 464561 Wikidata Q24598202 D A Hopwood F Malpartida H M Kieser et al 1 April 1985 Production of hybrid antibiotics by genetic engineering Nature 314 6012 642 644 doi 10 1038 314642A0 ISSN 1476 4687 PMID 3857464 Wikidata Q59071761 H Ikeda T Nonomiya M Usami T Ohta Satoshi Ōmura 1 August 1999 Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis Proceedings of the National Academy of Sciences of the United States of America 96 17 9509 9514 Bibcode 1999PNAS 96 9509I doi 10 1073 PNAS 96 17 9509 ISSN 0027 8424 PMC 22239 PMID 10449723 Wikidata Q33871234 Masahiko Hayashi Mun Chual Rho Akiko Enomoto et al 4 November 2002 Suppression of bone resorption by madindoline A a novel nonpeptide antagonist to gp130 Proceedings of the National Academy of Sciences of the United States of America 99 23 14728 14733 Bibcode 2002PNAS 9914728H doi 10 1073 PNAS 232562799 ISSN 0027 8424 PMC 137487 PMID 12417753 Wikidata Q34379185 Tomoyasu Hirose Toshiaki Sunazuka Satoshi Omura 1 January 2010 Recent development of two chitinase inhibitors Argifin and Argadin produced by soil microorganisms Proceedings of the Japan Academy Series B 86 2 85 102 doi 10 2183 PJAB 86 85 ISSN 0386 2208 PMC 3417560 PMID 20154467 Wikidata Q34098670 Nobuyuki Matoba Adam S Husk Brian W Barnett et al 2010 HIV 1 neutralization profile and plant based recombinant expression of actinohivin an Env glycan specific lectin devoid of T cell mitogenic activity PLOS One 5 6 e11143 Bibcode 2010PLoSO 511143M doi 10 1371 JOURNAL PONE 0011143 ISSN 1932 6203 PMC 2886112 PMID 20559567 Wikidata Q21076115 Hirofumi Nakano Satoshi Omura 9 January 2009 Chemical biology of natural indolocarbazole products 30 years since the discovery of staurosporine The Journal of Antibiotics 62 1 17 26 doi 10 1038 JA 2008 4 ISSN 0021 8820 PMID 19132059 Wikidata Q34918248 Ōmura S 2011 Microbial metabolites 45 years of wandering wondering and discovering Tetrahedron 67 35 6420 6459 doi 10 1016 j tet 2011 03 117 Social role EditŌmura served as deputy director and director at the Kitasato Institute He was devoted to rebuild the laboratory and promoting the establishment of the medical center that is now Kitasato University Medical Center Meanwhile he established a path to rebuilding of the corporate school juridical person which has integrated with the School corporation Kitasato Gakuen He succeeded in establishing a new School corporation Kitasato Institute In addition he served as president of the School corporation Joshibi University of Art and Design twice and served as the honorary school chief of the School corporation Kaichi Gakuen 11 In 2007 he established the Nirasaki Omura Art Museum on his collection 12 Awards and honors Edit Satoshi Ōmura left and William C Campbell right in Stockholm December 2015 A Children s statues leading to adults of onchocerciasis before Kitasato University buildings were produced by sculptors of Burkina Faso in honor of Ōmura s contributions of avermectin and ivermectin a symbol of the campaign to eradicate onchocerciasis clarification needed 13 Similar life sized bronze statues were erected in World Health Organization WHO Headquarters where Carter Center Merck amp Co World Bank Headquarters and Burkina Faso s World Health Organization Africa Onchocerciasis Control Program clarification needed 1985 Hoechst Roussel Award 14 1986 The Pharmaceutical Society of Japan Award 14 1988 Uehara Prize 14 1990 Japan Academy Prize academics 14 1992 Medal with Purple Ribbon 14 1995 Fujihara Award 14 1997 Robert Koch Gold Medal 15 1998 Prince Mahidol Award 14 2000 Nakanishi Prize American Chemical Society and Chemical Society of Japan 14 2005 Ernest Guenther Award in the Chemistry of Natural Products American Chemical Society 14 2007 Hamao Umezawa Memorial Award 14 2008 Knight of the Legion of Honour of France 2010 Tetrahedron Prize for Creativity in Organic Chemistry 14 2011 Arima Award 14 2011 Order of the Sacred Treasure Gold and Silver Star 16 2012 Person of Cultural Merit 14 2014 Canada Gairdner Global Health Award 17 2015 Asahi Prize 14 2015 The Order of Cultural Merit 14 2015 Nobel Prize in Physiology or Medicine Honorary doctorates Edit List of honorary doctorates 18 1992 Lajos Kossuth University Hungary 1994 Wesleyan University USA 2016 Shanghai Jiao Tong University China 2018 University of St Andrews ScotlandLearned societies membership Edit1992 Academy of Sciences Leopoldina 19 1999 National Academy of Sciences 20 2001 Japan Academy 21 2002 Academie des sciences 22 2005 Russian Academy of Sciences 2005 Royal Society of Chemistry 2005 Academia Europaea 2006 Chinese Academy of Engineering 2009 Japan Society for Bioscience Biotechnology and Agrochemistry 2014 Pharmaceutical Society of Japan ja 2016 Japan Pharmaceutical Association 2016 Japan Society of Synthetic Organic Chemistry 2016 Japan Society of ChemotherapySee also EditLactacystin Cerulenin Andrastin A Herbimycin and Neoxaline Koji Nakanishi Tohru Fukuyama Kitasato Shibasaburō List of Japanese Nobel laureates List of Nobel laureates affiliated with the University of TokyoReferences Edit The Nobel Prize in Physiology or Medicine 2015 Nobel Prize Outreach AB 6 October 2015 a b c Andy Crump Satoshi Ōmura 1 January 2011 Ivermectin wonder drug from Japan the human use perspective Proceedings of the Japan Academy Series B 87 2 13 28 Bibcode 2011PJAB 87 13C doi 10 2183 PJAB 87 13 ISSN 0386 2208 PMC 3043740 PMID 21321478 Wikidata Q34598257 a b Satoshi Omura PhD Retrieved 5 October 2015 a b 大村智北里研究所顧問 北里大学名誉教授が文化功労者に 北里大学 2012年11月1日 from ストックホルム これからは人材の育成に努力します 大村先生が語った受賞後の活動 TUSToday 2015 12 18 人間発見 日本経済新聞2010年7月14日 ノーベル賞受賞 大村智氏 常識破りの発想で治療薬開発 産経ニュース2015 10 5 新しい微生物創薬の世界を切り開く JT Press release NobelPrize org Japanese microbiologist Satoshi Omura shares Nobel Prize for medicine The Japan Times 5 October 2015 Retrieved 5 October 2015 大村先生 開智学園高等部 Retrieved 2015 10 12 韮崎大村美術館 館長あいさつ 大村智 韮崎大村美術館 Archived from the original on 2015 10 15 Retrieved 2015 10 12 新しい微生物創薬の世界を切り開く 大村 智 サイエンティスト ライブラリー JT生命誌研究館 Retrieved 14 March 2022 a b c d e f g h i j k l m n o Satoshi Ōmura Satoshi Ōmura Curriculum Vitae PDF Robert Koch Gold Medal Robert Koch Stiftung e V Retrieved 2015 10 05 政府 11年 春の叙勲 森田氏に旭重 大村氏が瑞重 薬事日報 2011年6月20日 Satoshi Ōmura Retrieved 14 March 2022 http www satoshi omura info biography omura cv pdf bare URL PDF List of Members Prof Dr Dr Satoshi Ōmura Retrieved 14 March 2022 Satoshi Omura www nasonline org Retrieved 14 March 2022 Personal Information ŌMURA Satoshi The Japan Academy www japan acad go jp Retrieved 14 March 2022 Satoshi Omura Liste des membres de l Academie des sciences O Listes par ordre alphabetique Listes des membres Membres Nous connaitre www academie sciences fr Retrieved 14 March 2022 External links EditProfessor Satoshi Omura Satoshi Ōmura People THE KITASATO INSTITUTE Nirasaki Omura Art Museum Satoshi Ōmura Quotes With Pictures Satoshi Ōmura on Nobelprize org Retrieved from https en wikipedia org w index php title Satoshi Ōmura amp oldid 1090153649, wikipedia, wiki, book, books, library,

article

, read, download, free, free download, mp3, video, mp4, 3gp, jpg, jpeg, gif, png, picture, music, song, movie, book, game, games.