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SND1

December 20, 2023

Staphylococcal nuclease domain-containing protein 1 also known as 100 kDa coactivator or Tudor domain-containing protein 11 (TDRD11) is a protein that in humans is encoded by the SND1 gene.[5][6][7][8] SND1 is a main component of RISC complex[9] and plays an important role in miRNA function.[10][11] SND1 is Tudor domain containing protein and Tudor Proteins are highly conserved proteins and even present in Drosophila melanogaster.[12] SND1 is also involved in Autism.[13]

SND1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSND1, TDRD11, p100, staphylococcal nuclease and tudor domain containing 1, Tudor-SN
External IDsOMIM: 602181 MGI: 1929266 HomoloGene: 8665 GeneCards: SND1
Orthologs
SpeciesHumanMouse
Entrez

27044

56463

Ensembl

ENSG00000197157

ENSMUSG00000001424

UniProt

Q7KZF4

Q78PY7

RefSeq (mRNA)

NM_014390

NM_019776

RefSeq (protein)

NP_055205

NP_062750

Location (UCSC)Chr 7: 127.65 – 128.09 MbChr 6: 28.48 – 28.94 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Clinical significance edit

SND1 acts as oncogene in many cancers[14][15][16] and in hepatocellular carcinoma progression.[10][11] SND1 promotes tumor angiogenesis in human hepatocellular carcinoma through a novel pathway which involves NF-kappaB and miR-221.[17] SND1 promotes migration and invasion via angiotensin II type 1 receptor and TGFβ signaling.[18] SND1 expression is regulated by Mir-184 in gliomas.[19]

Interactions edit

SND1 has been shown to interact with MYB,[20]

SND1 also interacts with G3BP (stress granule protein)[25] and AEG-1.[10][11]

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000197157 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001424 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Tong X, Drapkin R, Yalamanchili R, Mosialos G, Kieff E (Sep 1995). "The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE". Molecular and Cellular Biology. 15 (9): 4735–44. doi:10.1128/mcb.15.9.4735. PMC 230717. PMID 7651391.
  6. ^ Callebaut I, Mornon JP (Jan 1997). "The human EBNA-2 coactivator p100: multidomain organization and relationship to the staphylococcal nuclease fold and to the tudor protein involved in Drosophila melanogaster development". The Biochemical Journal. 321 (1): 125–32. doi:10.1042/bj3210125. PMC 1218045. PMID 9003410.
  7. ^ Paukku K, Yang J, Silvennoinen O (Sep 2003). "Tudor and nuclease-like domains containing protein p100 function as coactivators for signal transducer and activator of transcription 5". Molecular Endocrinology. 17 (9): 1805–14. doi:10.1210/me.2002-0256. PMID 12819296.
  8. ^ "Entrez Gene: SND1 staphylococcal nuclease and tudor domain containing 1".
  9. ^ Tsuchiya N, Ochiai M, Nakashima K, Ubagai T, Sugimura T, Nakagama H (Oct 2007). "SND1, a component of RNA-induced silencing complex, is up-regulated in human colon cancers and implicated in early stage colon carcinogenesis". Cancer Research. 67 (19): 9568–76. doi:10.1158/0008-5472.CAN-06-2707. PMID 17909068.
  10. ^ a b c Yoo BK, Santhekadur PK, Gredler R, Chen D, Emdad L, Bhutia S, Pannell L, Fisher PB, Sarkar D (May 2011). "Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma". Hepatology. 53 (5): 1538–48. doi:10.1002/hep.24216. PMC 3081619. PMID 21520169.
  11. ^ a b c Yoo BK, Emdad L, Lee SG, Su ZZ, Santhekadur P, Chen D, Gredler R, Fisher PB, Sarkar D (Apr 2011). "Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology". Pharmacology & Therapeutics. 130 (1): 1–8. doi:10.1016/j.pharmthera.2011.01.008. PMC 3043119. PMID 21256156.
  12. ^ Ying, Muying; Chen, Dahua (1 January 2012). "Tudor domain-containing proteins of Drosophila melanogaster". Development, Growth & Differentiation. 54 (1): 32–43. doi:10.1111/j.1440-169X.2011.01308.x. PMID 23741747. S2CID 23227910.
  13. ^ Holt R, Barnby G, Maestrini E, Bacchelli E, Brocklebank D, Sousa I, Mulder EJ, Kantojärvi K, Järvelä I, Klauck SM, Poustka F, Bailey AJ, Monaco AP (Sep 2010). "Linkage and candidate gene studies of autism spectrum disorders in European populations". European Journal of Human Genetics. 18 (9): 1013–9. doi:10.1038/ejhg.2010.69. PMC 2987412. PMID 20442744.
  14. ^ Tsuchiya N, Nakagama H (Nov 2010). "MicroRNA, SND1, and alterations in translational regulation in colon carcinogenesis". Mutation Research. 693 (1–2): 94–100. doi:10.1016/j.mrfmmm.2010.09.001. PMID 20883704.
  15. ^ Kuruma H, Kamata Y, Takahashi H, Igarashi K, Kimura T, Miki K, Miki J, Sasaki H, Hayashi N, Egawa S (Jun 2009). "Staphylococcal nuclease domain-containing protein 1 as a potential tissue marker for prostate cancer". The American Journal of Pathology. 174 (6): 2044–50. doi:10.2353/ajpath.2009.080776. PMC 2684170. PMID 19435788.
  16. ^ Ho J, Kong JW, Choong LY, Loh MC, Toy W, Chong PK, Wong CH, Wong CY, Shah N, Lim YP (Feb 2009). "Novel breast cancer metastasis-associated proteins". Journal of Proteome Research. 8 (2): 583–94. doi:10.1021/pr8007368. PMID 19086899.
  17. ^ Santhekadur PK, Das SK, Gredler R, Chen D, Srivastava J, Robertson C, Baldwin AS, Fisher PB, Sarkar D (Apr 2012). "Multifunction protein staphylococcal nuclease domain containing 1 (SND1) promotes tumor angiogenesis in human hepatocellular carcinoma through novel pathway that involves nuclear factor κB and miR-221". The Journal of Biological Chemistry. 287 (17): 13952–8. doi:10.1074/jbc.M111.321646. PMC 3340184. PMID 22396537.
  18. ^ Santhekadur PK, Akiel M, Emdad L, Gredler R, Srivastava J, Rajasekaran D, Robertson CL, Mukhopadhyay ND, Fisher PB, Sarkar D (2014). "Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFβ signaling". FEBS Open Bio. 4: 353–61. doi:10.1016/j.fob.2014.03.012. PMC 4050181. PMID 24918049.
  19. ^ Emdad L, Janjic A, Alzubi MA, Hu B, Santhekadur PK, Menezes ME, Shen XN, Das SK, Sarkar D, Fisher PB (Mar 2015). "Suppression of miR-184 in malignant gliomas upregulates SND1 and promotes tumor aggressiveness". Neuro-Oncology. 17 (3): 419–29. doi:10.1093/neuonc/nou220. PMC 4483100. PMID 25216670.
  20. ^ Dash AB, Orrico FC, Ness SA (Aug 1996). "The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb". Genes & Development. 10 (15): 1858–69. doi:10.1101/gad.10.15.1858. PMID 8756344.
  21. ^ Leverson JD, Koskinen PJ, Orrico FC, Rainio EM, Jalkanen KJ, Dash AB, Eisenman RN, Ness SA (Oct 1998). "Pim-1 kinase and p100 cooperate to enhance c-Myb activity". Molecular Cell. 2 (4): 417–25. doi:10.1016/S1097-2765(00)80141-0. PMID 9809063.
  22. ^ a b Yang J, Aittomäki S, Pesu M, Carter K, Saarinen J, Kalkkinen N, Kieff E, Silvennoinen O (Sep 2002). "Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II". The EMBO Journal. 21 (18): 4950–8. doi:10.1093/emboj/cdf463. PMC 126276. PMID 12234934.
  23. ^ Zhou S, Fujimuro M, Hsieh JJ, Chen L, Hayward SD (Feb 2000). "A role for SKIP in EBNA2 activation of CBF1-repressed promoters". Journal of Virology. 74 (4): 1939–47. doi:10.1128/jvi.74.4.1939-1947.2000. PMC 111672. PMID 10644367.
  24. ^ Hsieh JJ, Zhou S, Chen L, Young DB, Hayward SD (Jan 1999). "CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex". Proceedings of the National Academy of Sciences of the United States of America. 96 (1): 23–8. Bibcode:1999PNAS...96...23H. doi:10.1073/pnas.96.1.23. PMC 15086. PMID 9874765.
  25. ^ Gao X, Ge L, Shao J, Su C, Zhao H, Saarikettu J, Yao X, Yao Z, Silvennoinen O, Yang J (Aug 2010). "Tudor-SN interacts with and co-localizes with G3BP in stress granules under stress conditions". FEBS Letters. 584 (16): 3525–32. doi:10.1016/j.febslet.2010.07.022. PMC 7127458. PMID 20643132.

Further reading edit

  • Dash AB, Orrico FC, Ness SA (Aug 1996). "The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb". Genes & Development. 10 (15): 1858–69. doi:10.1101/gad.10.15.1858. PMID 8756344.
  • Leverson JD, Koskinen PJ, Orrico FC, Rainio EM, Jalkanen KJ, Dash AB, Eisenman RN, Ness SA (Oct 1998). "Pim-1 kinase and p100 cooperate to enhance c-Myb activity". Molecular Cell. 2 (4): 417–25. doi:10.1016/S1097-2765(00)80141-0. PMID 9809063.
  • Liénard P, Rivière M, Van Vooren P, Szpirer C, Szpirer J (2001). "Assignment of SND1, the gene encoding coactivator p100, to human chromosome 7q31.3 and rat chromosome 4q23 by in situ hybridization". Cytogenetics and Cell Genetics. 90 (3–4): 253–4. doi:10.1159/000056783. PMID 11124528. S2CID 46217878.
  • Rushton JJ, Ness SA (2001). "The conserved DNA binding domain mediates similar regulatory interactions for A-Myb, B-Myb, and c-Myb transcription factors". Blood Cells, Molecules & Diseases. 27 (2): 459–63. doi:10.1006/bcmd.2001.0405. PMID 11259168.
  • Broadhurst MK, Wheeler TT (Nov 2001). "The p100 coactivator is present in the nuclei of mammary epithelial cells and its abundance is increased in response to prolactin in culture and in mammary tissue during lactation". The Journal of Endocrinology. 171 (2): 329–37. doi:10.1677/joe.0.1710329. PMID 11691653.
  • Yang J, Aittomäki S, Pesu M, Carter K, Saarinen J, Kalkkinen N, Kieff E, Silvennoinen O (Sep 2002). "Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II". The EMBO Journal. 21 (18): 4950–8. doi:10.1093/emboj/cdf463. PMC 126276. PMID 12234934.
  • Tijms MA, Snijder EJ (Sep 2003). "Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100". The Journal of General Virology. 84 (Pt 9): 2317–22. doi:10.1099/vir.0.19297-0. PMID 12917451.
  • Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ (Jan 2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nature Biotechnology. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. S2CID 7200157.
  • Broadhurst MK, Lee RS, Hawkins S, Wheeler TT (Jan 2005). "The p100 EBNA-2 coactivator: a highly conserved protein found in a range of exocrine and endocrine cells and tissues in cattle". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1681 (2–3): 126–33. doi:10.1016/j.bbaexp.2004.10.009. PMID 15627504.
  • Välineva T, Yang J, Palovuori R, Silvennoinen O (Apr 2005). "The transcriptional co-activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6". The Journal of Biological Chemistry. 280 (15): 14989–96. doi:10.1074/jbc.M410465200. PMID 15695802.
  • Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF (Nov 2006). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes". Journal of Proteome Research. 5 (11): 3135–44. doi:10.1021/pr060363j. PMID 17081065.
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

December 20, 2023
snd1, staphylococcal, nuclease, domain, containing, protein, also, known, coactivator, tudor, domain, containing, protein, tdrd11, protein, that, humans, encoded, gene, main, component, risc, complex, plays, important, role, mirna, function, tudor, domain, con. Staphylococcal nuclease domain containing protein 1 also known as 100 kDa coactivator or Tudor domain containing protein 11 TDRD11 is a protein that in humans is encoded by the SND1 gene 5 6 7 8 SND1 is a main component of RISC complex 9 and plays an important role in miRNA function 10 11 SND1 is Tudor domain containing protein and Tudor Proteins are highly conserved proteins and even present in Drosophila melanogaster 12 SND1 is also involved in Autism 13 SND1Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMGIdentifiersAliasesSND1 TDRD11 p100 staphylococcal nuclease and tudor domain containing 1 Tudor SNExternal IDsOMIM 602181 MGI 1929266 HomoloGene 8665 GeneCards SND1Gene location Human Chr Chromosome 7 human 1 Band7q32 1Start127 652 194 bp 1 End128 092 609 bp 1 Gene location Mouse Chr Chromosome 6 mouse 2 Band6 6 A3 3Start28 475 138 bp 2 End28 935 161 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inbody of pancreasstromal cell of endometriumislet of Langerhansparotid glandcanal of the cervixsmooth muscle tissueanterior pituitarybody of stomachmonocytebone marrow cellsTop expressed inlacrimal glandparotid glandyolk saclipmolarplacentaseminal vesiculaatriumislet of LangerhansuterusMore reference expression dataBioGPSn aGene ontologyMolecular functionprotein binding transcription coregulator activity nucleic acid binding nuclease activity RNA binding cadherin binding endonuclease activity endoribonuclease activity hydrolase activity RISC complex bindingCellular componentmelanosome RISC complex extracellular exosome mitochondrion membrane dense body cytoplasm cytosol nucleusBiological processgene silencing viral process regulation of transcription DNA templated osteoblast differentiation transcription DNA templated nucleic acid phosphodiester bond hydrolysis RNA catabolic process regulation of cell cycle process miRNA catabolic process RNA phosphodiester bond hydrolysis endonucleolytic regulation of nucleic acid templated transcriptionSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez2704456463EnsemblENSG00000197157ENSMUSG00000001424UniProtQ7KZF4Q78PY7RefSeq mRNA NM 014390NM 019776RefSeq protein NP 055205NP 062750Location UCSC Chr 7 127 65 128 09 MbChr 6 28 48 28 94 MbPubMed search 3 4 WikidataView Edit HumanView Edit Mouse Contents 1 Clinical significance 2 Interactions 3 References 4 Further readingClinical significance editSND1 acts as oncogene in many cancers 14 15 16 and in hepatocellular carcinoma progression 10 11 SND1 promotes tumor angiogenesis in human hepatocellular carcinoma through a novel pathway which involves NF kappaB and miR 221 17 SND1 promotes migration and invasion via angiotensin II type 1 receptor and TGFb signaling 18 SND1 expression is regulated by Mir 184 in gliomas 19 Interactions editSND1 has been shown to interact with MYB 20 PIM1 21 POLR2A 22 RBPJ 23 24 and STAT6 22 SND1 also interacts with G3BP stress granule protein 25 and AEG 1 10 11 References edit a b c GRCh38 Ensembl release 89 ENSG00000197157 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000001424 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Tong X Drapkin R Yalamanchili R Mosialos G Kieff E Sep 1995 The Epstein Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE Molecular and Cellular Biology 15 9 4735 44 doi 10 1128 mcb 15 9 4735 PMC 230717 PMID 7651391 Callebaut I Mornon JP Jan 1997 The human EBNA 2 coactivator p100 multidomain organization and relationship to the staphylococcal nuclease fold and to the tudor protein involved in Drosophila melanogaster development The Biochemical Journal 321 1 125 32 doi 10 1042 bj3210125 PMC 1218045 PMID 9003410 Paukku K Yang J Silvennoinen O Sep 2003 Tudor and nuclease like domains containing protein p100 function as coactivators for signal transducer and activator of transcription 5 Molecular Endocrinology 17 9 1805 14 doi 10 1210 me 2002 0256 PMID 12819296 Entrez Gene SND1 staphylococcal nuclease and tudor domain containing 1 Tsuchiya N Ochiai M Nakashima K Ubagai T Sugimura T Nakagama H Oct 2007 SND1 a component of RNA induced silencing complex is up regulated in human colon cancers and implicated in early stage colon carcinogenesis Cancer Research 67 19 9568 76 doi 10 1158 0008 5472 CAN 06 2707 PMID 17909068 a b c Yoo BK Santhekadur PK Gredler R Chen D Emdad L Bhutia S Pannell L Fisher PB Sarkar D May 2011 Increased RNA induced silencing complex RISC activity contributes to hepatocellular carcinoma Hepatology 53 5 1538 48 doi 10 1002 hep 24216 PMC 3081619 PMID 21520169 a b c Yoo BK Emdad L Lee SG Su ZZ Santhekadur P Chen D Gredler R Fisher PB Sarkar D Apr 2011 Astrocyte elevated gene 1 AEG 1 A multifunctional regulator of normal and abnormal physiology Pharmacology amp Therapeutics 130 1 1 8 doi 10 1016 j pharmthera 2011 01 008 PMC 3043119 PMID 21256156 Ying Muying Chen Dahua 1 January 2012 Tudor domain containing proteins of Drosophila melanogaster Development Growth amp Differentiation 54 1 32 43 doi 10 1111 j 1440 169X 2011 01308 x PMID 23741747 S2CID 23227910 Holt R Barnby G Maestrini E Bacchelli E Brocklebank D Sousa I Mulder EJ Kantojarvi K Jarvela I Klauck SM Poustka F Bailey AJ Monaco AP Sep 2010 Linkage and candidate gene studies of autism spectrum disorders in European populations European Journal of Human Genetics 18 9 1013 9 doi 10 1038 ejhg 2010 69 PMC 2987412 PMID 20442744 Tsuchiya N Nakagama H Nov 2010 MicroRNA SND1 and alterations in translational regulation in colon carcinogenesis Mutation Research 693 1 2 94 100 doi 10 1016 j mrfmmm 2010 09 001 PMID 20883704 Kuruma H Kamata Y Takahashi H Igarashi K Kimura T Miki K Miki J Sasaki H Hayashi N Egawa S Jun 2009 Staphylococcal nuclease domain containing protein 1 as a potential tissue marker for prostate cancer The American Journal of Pathology 174 6 2044 50 doi 10 2353 ajpath 2009 080776 PMC 2684170 PMID 19435788 Ho J Kong JW Choong LY Loh MC Toy W Chong PK Wong CH Wong CY Shah N Lim YP Feb 2009 Novel breast cancer metastasis associated proteins Journal of Proteome Research 8 2 583 94 doi 10 1021 pr8007368 PMID 19086899 Santhekadur PK Das SK Gredler R Chen D Srivastava J Robertson C Baldwin AS Fisher PB Sarkar D Apr 2012 Multifunction protein staphylococcal nuclease domain containing 1 SND1 promotes tumor angiogenesis in human hepatocellular carcinoma through novel pathway that involves nuclear factor kB and miR 221 The Journal of Biological Chemistry 287 17 13952 8 doi 10 1074 jbc M111 321646 PMC 3340184 PMID 22396537 Santhekadur PK Akiel M Emdad L Gredler R Srivastava J Rajasekaran D Robertson CL Mukhopadhyay ND Fisher PB Sarkar D 2014 Staphylococcal nuclease domain containing 1 SND1 promotes migration and invasion via angiotensin II type 1 receptor AT1R and TGFb signaling FEBS Open Bio 4 353 61 doi 10 1016 j fob 2014 03 012 PMC 4050181 PMID 24918049 Emdad L Janjic A Alzubi MA Hu B Santhekadur PK Menezes ME Shen XN Das SK Sarkar D Fisher PB Mar 2015 Suppression of miR 184 in malignant gliomas upregulates SND1 and promotes tumor aggressiveness Neuro Oncology 17 3 419 29 doi 10 1093 neuonc nou220 PMC 4483100 PMID 25216670 Dash AB Orrico FC Ness SA Aug 1996 The EVES motif mediates both intermolecular and intramolecular regulation of c Myb Genes amp Development 10 15 1858 69 doi 10 1101 gad 10 15 1858 PMID 8756344 Leverson JD Koskinen PJ Orrico FC Rainio EM Jalkanen KJ Dash AB Eisenman RN Ness SA Oct 1998 Pim 1 kinase and p100 cooperate to enhance c Myb activity Molecular Cell 2 4 417 25 doi 10 1016 S1097 2765 00 80141 0 PMID 9809063 a b Yang J Aittomaki S Pesu M Carter K Saarinen J Kalkkinen N Kieff E Silvennoinen O Sep 2002 Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II The EMBO Journal 21 18 4950 8 doi 10 1093 emboj cdf463 PMC 126276 PMID 12234934 Zhou S Fujimuro M Hsieh JJ Chen L Hayward SD Feb 2000 A role for SKIP in EBNA2 activation of CBF1 repressed promoters Journal of Virology 74 4 1939 47 doi 10 1128 jvi 74 4 1939 1947 2000 PMC 111672 PMID 10644367 Hsieh JJ Zhou S Chen L Young DB Hayward SD Jan 1999 CIR a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex Proceedings of the National Academy of Sciences of the United States of America 96 1 23 8 Bibcode 1999PNAS 96 23H doi 10 1073 pnas 96 1 23 PMC 15086 PMID 9874765 Gao X Ge L Shao J Su C Zhao H Saarikettu J Yao X Yao Z Silvennoinen O Yang J Aug 2010 Tudor SN interacts with and co localizes with G3BP in stress granules under stress conditions FEBS Letters 584 16 3525 32 doi 10 1016 j febslet 2010 07 022 PMC 7127458 PMID 20643132 Further reading editDash AB Orrico FC Ness SA Aug 1996 The EVES motif mediates both intermolecular and intramolecular regulation of c Myb Genes amp Development 10 15 1858 69 doi 10 1101 gad 10 15 1858 PMID 8756344 Leverson JD Koskinen PJ Orrico FC Rainio EM Jalkanen KJ Dash AB Eisenman RN Ness SA Oct 1998 Pim 1 kinase and p100 cooperate to enhance c Myb activity Molecular Cell 2 4 417 25 doi 10 1016 S1097 2765 00 80141 0 PMID 9809063 Lienard P Riviere M Van Vooren P Szpirer C Szpirer J 2001 Assignment of SND1 the gene encoding coactivator p100 to human chromosome 7q31 3 and rat chromosome 4q23 by in situ hybridization Cytogenetics and Cell Genetics 90 3 4 253 4 doi 10 1159 000056783 PMID 11124528 S2CID 46217878 Rushton JJ Ness SA 2001 The conserved DNA binding domain mediates similar regulatory interactions for A Myb B Myb and c Myb transcription factors Blood Cells Molecules amp Diseases 27 2 459 63 doi 10 1006 bcmd 2001 0405 PMID 11259168 Broadhurst MK Wheeler TT Nov 2001 The p100 coactivator is present in the nuclei of mammary epithelial cells and its abundance is increased in response to prolactin in culture and in mammary tissue during lactation The Journal of Endocrinology 171 2 329 37 doi 10 1677 joe 0 1710329 PMID 11691653 Yang J Aittomaki S Pesu M Carter K Saarinen J Kalkkinen N Kieff E Silvennoinen O Sep 2002 Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II The EMBO Journal 21 18 4950 8 doi 10 1093 emboj cdf463 PMC 126276 PMID 12234934 Tijms MA Snijder EJ Sep 2003 Equine arteritis virus non structural protein 1 an essential factor for viral subgenomic mRNA synthesis interacts with the cellular transcription co factor p100 The Journal of General Virology 84 Pt 9 2317 22 doi 10 1099 vir 0 19297 0 PMID 12917451 Rush J Moritz A Lee KA Guo A Goss VL Spek EJ Zhang H Zha XM Polakiewicz RD Comb MJ Jan 2005 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells Nature Biotechnology 23 1 94 101 doi 10 1038 nbt1046 PMID 15592455 S2CID 7200157 Broadhurst MK Lee RS Hawkins S Wheeler TT Jan 2005 The p100 EBNA 2 coactivator a highly conserved protein found in a range of exocrine and endocrine cells and tissues in cattle Biochimica et Biophysica Acta BBA Gene Structure and Expression 1681 2 3 126 33 doi 10 1016 j bbaexp 2004 10 009 PMID 15627504 Valineva T Yang J Palovuori R Silvennoinen O Apr 2005 The transcriptional co activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB binding protein and STAT6 The Journal of Biological Chemistry 280 15 14989 96 doi 10 1074 jbc M410465200 PMID 15695802 Chi A Valencia JC Hu ZZ Watabe H Yamaguchi H Mangini NJ Huang H Canfield VA Cheng KC Yang F Abe R Yamagishi S Shabanowitz J Hearing VJ Wu C Appella E Hunt DF Nov 2006 Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes Journal of Proteome Research 5 11 3135 44 doi 10 1021 pr060363j PMID 17081065 Olsen JV Blagoev B Gnad F Macek B Kumar C Mortensen P Mann M Nov 2006 Global in vivo and site specific phosphorylation dynamics in signaling networks Cell 127 3 635 48 doi 10 1016 j cell 2006 09 026 PMID 17081983 S2CID 7827573 Retrieved from https en wikipedia org w index php title SND1 amp oldid 1136255259, wikipedia, wiki, book, books, library,

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