^Lucas G, Rymar VV, Du J, Mnie-Filali O, Bisgaard C, Manta S, Lambas-Senas L, Wiborg O, Haddjeri N, Piñeyro G, Sadikot AF, Debonnel G (2007). "Serotonin(4) (5-HT(4)) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action". Neuron. 55 (5): 712–25. doi:10.1016/j.neuron.2007.07.041. PMID 17785179. S2CID 14558104.
^Lamirault L, Simon H (2001). "Enhancement of place and object recognition memory in young adult and old rats by RS 67333, a partial agonist of 5-HT4 receptors". Neuropharmacology. 41 (7): 844–53. doi:10.1016/S0028-3908(01)00123-X. PMID 11684148. S2CID 31707593.
^Cho S, Hu Y (2007). "Activation of 5-HT4 receptors inhibits secretion of beta-amyloid peptides and increases neuronal survival". Experimental Neurology. 203 (1): 274–8. doi:10.1016/j.expneurol.2006.07.021. PMID 16978609. S2CID 41975593.
^Eglen RM, Bonhaus DW, Johnson LG, Leung E, Clark RD (August 1995). "Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo". Br. J. Pharmacol. 115 (8): 1387–92. doi:10.1111/j.1476-5381.1995.tb16628.x. PMC1908873. PMID 8564196.
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.
drug, which, been, investigated, potential, rapid, acting, antidepressant, nootropic, treatment, alzheimer, disease, high, affinity, receptor, partial, agonist, well, sigma, receptor, ligand, both, subtypes, lesser, extent, identifiersiupac, name, amino, chlor. RS 67 333 is a drug which has been investigated as a potential rapid acting antidepressant 1 nootropic 2 and treatment for Alzheimer s disease 3 It is a high affinity 5 HT4 receptor partial agonist as well as a sigma receptor ligand of both subtypes to a lesser extent 4 RS 67 333IdentifiersIUPAC name 1 4 amino 5 chloro 2 methoxyphenyl 3 1 butyl 4 piperidinyl 1 propanoneCAS Number160845 95 4 YPubChem CID183782ChemSpider159808 NUNII39N8XG5C9ACompTox Dashboard EPA DTXSID90167010Chemical and physical dataFormulaC 19H 29Cl N 2O 2Molar mass352 90 g mol 13D model JSmol Interactive imageSMILES C CCC1CCN CC1 CCCC O c1c cc c c1 Cl N OCInChI InChI 1S C19H29ClN2O2 c1 3 4 9 22 10 7 14 8 11 22 5 6 18 23 15 12 16 20 17 21 13 19 15 24 2 h12 14H 3 11 21H2 1 2H3 NKey JBHLYIVFFLNISJ UHFFFAOYSA N N N Y what is this verify References edit Lucas G Rymar VV Du J Mnie Filali O Bisgaard C Manta S Lambas Senas L Wiborg O Haddjeri N Pineyro G Sadikot AF Debonnel G 2007 Serotonin 4 5 HT 4 Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action Neuron 55 5 712 25 doi 10 1016 j neuron 2007 07 041 PMID 17785179 S2CID 14558104 Lamirault L Simon H 2001 Enhancement of place and object recognition memory in young adult and old rats by RS 67333 a partial agonist of 5 HT4 receptors Neuropharmacology 41 7 844 53 doi 10 1016 S0028 3908 01 00123 X PMID 11684148 S2CID 31707593 Cho S Hu Y 2007 Activation of 5 HT4 receptors inhibits secretion of beta amyloid peptides and increases neuronal survival Experimental Neurology 203 1 274 8 doi 10 1016 j expneurol 2006 07 021 PMID 16978609 S2CID 41975593 Eglen RM Bonhaus DW Johnson LG Leung E Clark RD August 1995 Pharmacological characterization of two novel and potent 5 HT4 receptor agonists RS 67333 and RS 67506 in vitro and in vivo Br J Pharmacol 115 8 1387 92 doi 10 1111 j 1476 5381 1995 tb16628 x PMC 1908873 PMID 8564196 nbsp This drug article relating to the nervous system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title RS 67 333 amp oldid 1203024441, wikipedia, wiki, book, books, library,
