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Quinestradol

February 23, 2023

Not to be confused with Quinestrol.

Quinestradol (INN, BAN) (brand names Colpovis, Colpovister, Pentovis), also known as quinestradiol or quinestriol, as well as estriol 3-cyclopentyl ether (E3CPE), is a synthetic estrogen and estrogen ether which is no longer marketed.[1][2][3][4] It is the 3-cyclopentyl ether of estriol.[1] The medication has been studied in the treatment of stress incontinence in elderly women, with effectiveness observed.[3][4]

Quinestradol
Clinical data
Trade namesColpovis, Colpovister, Pentovis
Other namesQuinestradiol; Quinestriol; Estriol 3-cyclopentyl ether; E3CPE
Routes of
administration		By mouth
Drug classEstrogen; Estrogen ether
ATC code
  • None
Identifiers
  • (8R,9S,13S,14S,16R,17R)-3-cyclopentyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol
CAS Number
  • 1169-79-5 Y
PubChem CID
  • 14431
ChemSpider
  • 16735993
UNII
  • 422L8173W8
CompTox Dashboard (EPA)
  • DTXSID30878638
ECHA InfoCard100.013.294
Chemical and physical data
FormulaC23H32O3
Molar mass356.506 g·mol−1
3D model (JSmol)
  • Interactive image
  • CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)OC5CCCC5
  • InChI=1S/C23H32O3/c1-23-11-10-18-17-9-7-16(26-15-4-2-3-5-15)12-14(17)6-8-19(18)20(23)13-21(24)22(23)25/h7,9,12,15,18-22,24-25H,2-6,8,10-11,13H2,1H3/t18-,19-,20+,21-,22+,23+/m1/s1
  • Key:ODYKCPYPRCJXLY-PZORDLPLSA-N

See also

References

  1. ^ a b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 899–. ISBN 978-1-4757-2085-3.
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 905–. ISBN 978-3-88763-075-1.
  3. ^ a b Crosignani PG, Paoletti R, Sarrel PM, Wenger NK (6 December 2012). Women's Health in Menopause: Behaviour, Cancer, Cardiovascular Disease, Hormone Replacement Therapy. Springer Science & Business Media. pp. 245–. ISBN 978-94-011-1024-2.
  4. ^ a b Seifer DB (27 July 1999). Menopause: Endocrinology and Management. Springer Science & Business Media. pp. 161–. ISBN 978-1-59259-246-3.



 

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February 23, 2023
quinestradol, confused, with, quinestrol, brand, names, colpovis, colpovister, pentovis, also, known, quinestradiol, quinestriol, well, estriol, cyclopentyl, ether, e3cpe, synthetic, estrogen, estrogen, ether, which, longer, marketed, cyclopentyl, ether, estri. Not to be confused with Quinestrol Quinestradol INN BAN brand names Colpovis Colpovister Pentovis also known as quinestradiol or quinestriol as well as estriol 3 cyclopentyl ether E3CPE is a synthetic estrogen and estrogen ether which is no longer marketed 1 2 3 4 It is the 3 cyclopentyl ether of estriol 1 The medication has been studied in the treatment of stress incontinence in elderly women with effectiveness observed 3 4 QuinestradolClinical dataTrade namesColpovis Colpovister PentovisOther namesQuinestradiol Quinestriol Estriol 3 cyclopentyl ether E3CPERoutes ofadministrationBy mouthDrug classEstrogen Estrogen etherATC codeNoneIdentifiersIUPAC name 8R 9S 13S 14S 16R 17R 3 cyclopentyloxy 13 methyl 6 7 8 9 11 12 14 15 16 17 decahydrocyclopenta a phenanthrene 16 17 diolCAS Number1169 79 5 YPubChem CID14431ChemSpider16735993UNII422L8173W8CompTox Dashboard EPA DTXSID30878638ECHA InfoCard100 013 294Chemical and physical dataFormulaC 23H 32O 3Molar mass356 506 g mol 13D model JSmol Interactive imageSMILES CC12CCC3C C1CC C2O O CCC4 C3C CC C4 OC5CCCC5InChI InChI 1S C23H32O3 c1 23 11 10 18 17 9 7 16 26 15 4 2 3 5 15 12 14 17 6 8 19 18 20 23 13 21 24 22 23 25 h7 9 12 15 18 22 24 25H 2 6 8 10 11 13H2 1H3 t18 19 20 21 22 23 m1 s1Key ODYKCPYPRCJXLY PZORDLPLSA NSee also EditList of estrogens List of estrogen esters Ethers of steroidal estrogensReferences Edit a b Elks J 14 November 2014 The Dictionary of Drugs Chemical Data Chemical Data Structures and Bibliographies Springer pp 899 ISBN 978 1 4757 2085 3 Index Nominum 2000 International Drug Directory Taylor amp Francis January 2000 pp 905 ISBN 978 3 88763 075 1 a b Crosignani PG Paoletti R Sarrel PM Wenger NK 6 December 2012 Women s Health in Menopause Behaviour Cancer Cardiovascular Disease Hormone Replacement Therapy Springer Science amp Business Media pp 245 ISBN 978 94 011 1024 2 a b Seifer DB 27 July 1999 Menopause Endocrinology and Management Springer Science amp Business Media pp 161 ISBN 978 1 59259 246 3 This article about a steroid is a stub You can help Wikipedia by expanding it vte This drug article relating to the genito urinary system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Quinestradol amp oldid 1069997140, wikipedia, wiki, book, books, library,

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