fbpx
Wikipedia

Platypnea-orthodeoxia syndrome

Platypnea–orthodeoxia syndrome is a condition in which a person has shortness of breath and low oxygen saturations when upright (platypnea and orthodeoxia), but no symptoms when lying down. It can be caused by ventilation-perfusion mismatch, intracardiac shunting, or pulmonary shunting. In some cases, the cause is multifactorial.[1][2]

Platypnea-orthodeoxia syndrome
SpecialtyCardiology, cardiothoracic surgery (primarily),
pulmonology (secondarily),
neurology, hepatology and general surgery
Differential diagnosisIntracardiac shunting

Although the mechanism is still unclear, it is thought to be caused by right to left shunting of blood flow due to an anatomic defect allowing communication between right and left-sided circulation, such as an atrial septal defect, patent foramen ovale, or pulmonary atrioventricular malformations, and a functional component that causes blood to move through the shunt, such as Ebstein's Anomaly, pulmonary hypertension, or absent superior vena cava.[3]

References edit

  1. ^ Henkin, Stanislav; Negrotto, Sara; Pollak, Peter M.; Cullen, Michael W.; O'Cochlain, D. Fearghas; Wright, R. Scott (2015-10-01). "Platypnea-Orthodeoxia Syndrome: Diagnostic Challenge and the Importance of Heightened Clinical Suspicion". Texas Heart Institute Journal. 42 (5): 498–501. doi:10.14503/THIJ-14-4596. ISSN 0730-2347. PMC 4591898. PMID 26504452.
  2. ^ De Vecchis, Renato; Baldi, Cesare; Ariano, Carmelina (2016-09-23). "Platypnea–Orthodeoxia Syndrome: Multiple Pathophysiological Interpretations of a Clinical Picture Primarily Consisting of Orthostatic Dyspnea". Journal of Clinical Medicine. 5 (10): 85. doi:10.3390/jcm5100085. ISSN 2077-0383. PMC 5086587. PMID 27669319.
  3. ^ Knapper, Joseph T.; Schultz, Jason; Das, Gladwin; Sperling, Laurence S. (October 2014). "Cardiac Platypnea-Orthodeoxia Syndrome: An Often Unrecognized Malady: Cardiac Platypnea-Orthodeoxia Syndrome". Clinical Cardiology. 37 (10): 645–649. doi:10.1002/clc.22301. PMC 6649356. PMID 24912004.


platypnea, orthodeoxia, syndrome, platypnea, orthodeoxia, syndrome, condition, which, person, shortness, breath, oxygen, saturations, when, upright, platypnea, orthodeoxia, symptoms, when, lying, down, caused, ventilation, perfusion, mismatch, intracardiac, sh. Platypnea orthodeoxia syndrome is a condition in which a person has shortness of breath and low oxygen saturations when upright platypnea and orthodeoxia but no symptoms when lying down It can be caused by ventilation perfusion mismatch intracardiac shunting or pulmonary shunting In some cases the cause is multifactorial 1 2 Platypnea orthodeoxia syndromeSpecialtyCardiology cardiothoracic surgery primarily pulmonology secondarily neurology hepatology and general surgeryDifferential diagnosisIntracardiac shunting Although the mechanism is still unclear it is thought to be caused by right to left shunting of blood flow due to an anatomic defect allowing communication between right and left sided circulation such as an atrial septal defect patent foramen ovale or pulmonary atrioventricular malformations and a functional component that causes blood to move through the shunt such as Ebstein s Anomaly pulmonary hypertension or absent superior vena cava 3 References edit Henkin Stanislav Negrotto Sara Pollak Peter M Cullen Michael W O Cochlain D Fearghas Wright R Scott 2015 10 01 Platypnea Orthodeoxia Syndrome Diagnostic Challenge and the Importance of Heightened Clinical Suspicion Texas Heart Institute Journal 42 5 498 501 doi 10 14503 THIJ 14 4596 ISSN 0730 2347 PMC 4591898 PMID 26504452 De Vecchis Renato Baldi Cesare Ariano Carmelina 2016 09 23 Platypnea Orthodeoxia Syndrome Multiple Pathophysiological Interpretations of a Clinical Picture Primarily Consisting of Orthostatic Dyspnea Journal of Clinical Medicine 5 10 85 doi 10 3390 jcm5100085 ISSN 2077 0383 PMC 5086587 PMID 27669319 Knapper Joseph T Schultz Jason Das Gladwin Sperling Laurence S October 2014 Cardiac Platypnea Orthodeoxia Syndrome An Often Unrecognized Malady Cardiac Platypnea Orthodeoxia Syndrome Clinical Cardiology 37 10 645 649 doi 10 1002 clc 22301 PMC 6649356 PMID 24912004 nbsp This medical symptom article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Platypnea orthodeoxia syndrome amp oldid 1172585065, wikipedia, wiki, book, books, library,

article

, read, download, free, free download, mp3, video, mp4, 3gp, jpg, jpeg, gif, png, picture, music, song, movie, book, game, games.