^(PDF). Geneva: World Health Organization. 2002. Archived from the original (PDF) on July 3, 2011.
^Tsurushita N, Vasquez M (January 2004). "Humanization of monoclonal antibodies". In Reth M, Radbruch A, Alt F, Honjo T, Neuberger M (eds.). Molecular Biology of B Cells. Academic Press. pp. 533–545. ISBN978-0-08-047950-7.
technetium, 99mtc, nofetumomab, merpentan, trade, name, verluma, mouse, monoclonal, antibody, derivative, used, diagnosis, lung, cancer, gastrointestinal, breast, ovary, pancreas, kidney, cervix, bladder, carcinoma, antibody, part, nofetumomab, attached, chela. Technetium 99mTc nofetumomab merpentan trade name Verluma is a mouse monoclonal antibody derivative used in the diagnosis of lung cancer 1 gastrointestinal breast ovary pancreas kidney cervix and bladder carcinoma 2 The antibody part nofetumomab is attached to the chelator merpentan which links it to the radioisotope technetium 99m 99mTc 3 Technetium 99mTc nofetumomab merpentanMonoclonal antibodyTypeFab fragmentSourceMouseClinical dataTrade namesVerlumaATC codenonePharmacokinetic dataElimination half life10 5 hoursExcretionrenal 64 IdentifiersCAS Number165942 79 0 NChemSpidernoneUNII9UFH75HT7S N Y what is this verify Contents 1 Nofetumomab 2 Merpentan 2 1 Phenthioate 3 ReferencesNofetumomab editNofetumomab is an antibody fragment that recognises the pancarcinoma glycoprotein antigen EpCAM 4 and or CD20 MS4A1 5 It is the Fab part of murine MAb NR LU 10 6 Merpentan editThe chelator part merpentan is a phenthioate ligand 2 3 5 6 tetrafluorophenyl 4 5 bis 5 1 ethoxyethyl thioacetoamidopentanoate 6 Phenthioate edit Phenthioate is an insecticide Cidial O o dimethyl S carbethoxy phenylmethyl dithiophosphate 7 References edit Straka MR Joyce JM Myers DT January 2000 Tc 99m nofetumomab merpentan complements an equivocal bone scan for detecting skeletal metastatic disease from lung cancer Clinical Nuclear Medicine 25 1 54 5 doi 10 1097 00003072 200001000 00013 PMID 10634533 Breitz HB Tyler A Bjorn MJ Lesley T Weiden PL September 1997 Clinical experience with Tc 99m nofetumomab merpentan Verluma radioimmunoscintigraphy Clinical Nuclear Medicine 22 9 615 20 doi 10 1097 00003072 199709000 00007 PMID 9298295 International Nonproprietary Names INN for pharmaceutical substances PDF Geneva World Health Organization 2002 Archived from the original PDF on July 3 2011 Tsurushita N Vasquez M January 2004 Humanization of monoclonal antibodies In Reth M Radbruch A Alt F Honjo T Neuberger M eds Molecular Biology of B Cells Academic Press pp 533 545 ISBN 978 0 08 047950 7 Anti MS4A1 Therapeutic Antibody Technetium 99MTC Nofetumomab Merpentan Creative BioLabs a b Mudd E 27 February 2015 Monoclonal Antibody Radionuclide Test Kits Pharmacological Sciences US 3934010 Drabek J Varsanyi D Insecticidal composition and method utilizing phosphoric acid phenylsulphonamide esters issued 20 January 1976 assigned to Ciba Geigy Corporation nbsp This monoclonal antibody related article is a stub You can help Wikipedia by expanding it vte nbsp This antineoplastic or immunomodulatory drug article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Technetium 99mTc nofetumomab merpentan amp oldid 1084076675 Phenthioate, wikipedia, wiki, book, books, library,
