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Pathologic fracture

A pathologic fracture is a bone fracture caused by weakness of the bone structure that leads to decrease mechanical resistance to normal mechanical loads.[1] This process is most commonly due to osteoporosis, but may also be due to other pathologies such as cancer, infection (such as osteomyelitis), inherited bone disorders, or a bone cyst. Only a small number of conditions are commonly responsible for pathological fractures, including osteoporosis, osteomalacia, Paget's disease, Osteitis, osteogenesis imperfecta, benign bone tumours and cysts, secondary malignant bone tumours and primary malignant bone tumours.

Pathologic fracture
Other namesInsufficiency fracture
Pathological fracture of the humerus in a patient with metastasis of renal cell carcinoma
SpecialtyRheumatology 

Fragility fracture is a type of pathologic fracture that occurs as a result of an injury that would be insufficient to cause fracture in a normal bone.[2] There are three fracture sites said to be typical of fragility fractures: vertebral fractures, fractures of the neck of the femur, and Colles fracture of the wrist. This definition arises because a normal human being ought to be able to fall from standing height without breaking any bones, and a fracture, therefore, suggests weakness of the skeleton.

Pathological fractures present as a chalkstick fracture in long bones, and appear as a transverse fractures nearly 90 degrees to the long axis of the bone. In a pathological compression fracture of a spinal vertebra fractures will commonly appear to collapse the entire body of vertebra.

Cause edit

Pathologic fractures in children and adolescents can result from a diverse array of disorders namely; metabolic, endocrine, neoplastic, infectious, immunologic, and genetic skeletal dysplasias. [citation needed]

 
Juvenile osteoporosis

Miscellaneous causes edit

Diagnosis edit

In circumstances where other pathologies are excluded (for example, cancer), a pathologic fracture is diagnostic of osteoporosis irrespective of bone mineral density.[citation needed]

Management edit

Based on Mirel's score (if the score is more than 8), bone fixation should be done prophylactically. Fixation is done by internal fixation rather than conservatively, along with treatment of the underlying cause.[4]

References edit

  1. ^ Salehi, Sana; Abedi, Aidin; Gross, Jordan S.; Gholamrezanezhad, Ali (2019-06-22). "Prayer's fracture: rare cases of knee insufficiency fracture in non-weight-bearing femoral condyle". Clinical Imaging. 58: 80–83. doi:10.1016/j.clinimag.2019.06.013. ISSN 0899-7071. PMID 31279988. S2CID 195830673.
  2. ^ Vanasse, Alain; Dagenais, Pierre; Niyonsenga, Théophile; Grégoire, Jean-Pierre; Courteau, Josiane; Hemiari, Abbas (2005). "Bone mineral density measurement and osteoporosis treatment after a fragility fracture in older adults: regional variation and determinants of use in Quebec". BMC Musculoskeletal Disorders. 6 (1): 33. doi:10.1186/1471-2474-6-33. ISSN 1471-2474. PMC 1187894. PMID 15969760.
  3. ^ Maheswari. Essential Orthopedics (3 ed.). Jaypee Publications. p. 4.
  4. ^ Mirels H (October 2003). "Metastatic disease in long bones: A proposed scoring system for diagnosing impending pathologic fractures. 1989". Clin. Orthop. Relat. Res. (415 Suppl): S4–13. doi:10.1097/01.blo.0000093045.56370.dd. PMID 14600587. S2CID 43255503.

External links edit


pathologic, fracture, pathologic, fracture, bone, fracture, caused, weakness, bone, structure, that, leads, decrease, mechanical, resistance, normal, mechanical, loads, this, process, most, commonly, osteoporosis, also, other, pathologies, such, cancer, infect. A pathologic fracture is a bone fracture caused by weakness of the bone structure that leads to decrease mechanical resistance to normal mechanical loads 1 This process is most commonly due to osteoporosis but may also be due to other pathologies such as cancer infection such as osteomyelitis inherited bone disorders or a bone cyst Only a small number of conditions are commonly responsible for pathological fractures including osteoporosis osteomalacia Paget s disease Osteitis osteogenesis imperfecta benign bone tumours and cysts secondary malignant bone tumours and primary malignant bone tumours Pathologic fractureOther namesInsufficiency fracturePathological fracture of the humerus in a patient with metastasis of renal cell carcinomaSpecialtyRheumatology Fragility fracture is a type of pathologic fracture that occurs as a result of an injury that would be insufficient to cause fracture in a normal bone 2 There are three fracture sites said to be typical of fragility fractures vertebral fractures fractures of the neck of the femur and Colles fracture of the wrist This definition arises because a normal human being ought to be able to fall from standing height without breaking any bones and a fracture therefore suggests weakness of the skeleton Pathological fractures present as a chalkstick fracture in long bones and appear as a transverse fractures nearly 90 degrees to the long axis of the bone In a pathological compression fracture of a spinal vertebra fractures will commonly appear to collapse the entire body of vertebra Contents 1 Cause 1 1 Miscellaneous causes 2 Diagnosis 3 Management 4 References 5 External linksCause editPathologic fractures in children and adolescents can result from a diverse array of disorders namely metabolic endocrine neoplastic infectious immunologic and genetic skeletal dysplasias citation needed nbsp Juvenile osteoporosis Primary hyperparathyroidism Simple bone cyst Aneurismal bone cyst Osteoporosis Chronic osteomyelitis Osteogenesis imperfecta Osteomalacia Rickets Renal osteodystrophy Malignant infantile osteopetrosis juvenile osteoporosis juvenile rheumatoid arthritis Miscellaneous causes edit Monostotic fibrous dysplasia Eosinophilic granuloma Bone atrophy secondary to diseases like polio 3 Diagnosis editIn circumstances where other pathologies are excluded for example cancer a pathologic fracture is diagnostic of osteoporosis irrespective of bone mineral density citation needed Management editBased on Mirel s score if the score is more than 8 bone fixation should be done prophylactically Fixation is done by internal fixation rather than conservatively along with treatment of the underlying cause 4 References edit Salehi Sana Abedi Aidin Gross Jordan S Gholamrezanezhad Ali 2019 06 22 Prayer s fracture rare cases of knee insufficiency fracture in non weight bearing femoral condyle Clinical Imaging 58 80 83 doi 10 1016 j clinimag 2019 06 013 ISSN 0899 7071 PMID 31279988 S2CID 195830673 Vanasse Alain Dagenais Pierre Niyonsenga Theophile Gregoire Jean Pierre Courteau Josiane Hemiari Abbas 2005 Bone mineral density measurement and osteoporosis treatment after a fragility fracture in older adults regional variation and determinants of use in Quebec BMC Musculoskeletal Disorders 6 1 33 doi 10 1186 1471 2474 6 33 ISSN 1471 2474 PMC 1187894 PMID 15969760 Maheswari Essential Orthopedics 3 ed Jaypee Publications p 4 Mirels H October 2003 Metastatic disease in long bones A proposed scoring system for diagnosing impending pathologic fractures 1989 Clin Orthop Relat Res 415 Suppl S4 13 doi 10 1097 01 blo 0000093045 56370 dd PMID 14600587 S2CID 43255503 External links edit nbsp This oncology article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Pathologic fracture amp oldid 1059968346, wikipedia, wiki, book, books, library,

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