Prostaglandin F2 receptor negative regulator is a protein that in humans is encoded by the PTGFRNgene.[5][6] PTGFRN has also been designated as CD315 (cluster of differentiation 315).
^ abCharrin, S; Le Naour F; Oualid M; Billard M; Faure G; Hanash S M; Boucheix C; Rubinstein E (Apr 2001). "The major CD9 and CD81 molecular partner. Identification and characterization of the complexes". J. Biol. Chem. 276 (17). United States: 14329–37. doi:10.1074/jbc.M011297200. ISSN 0021-9258. PMID 11278880.
^ abStipp, C S; Orlicky D; Hemler M E (Feb 2001). "FPRP, a major, highly stoichiometric, highly specific CD81- and CD9-associated protein". J. Biol. Chem. 276 (7). United States: 4853–62. doi:10.1074/jbc.M009859200. ISSN 0021-9258. PMID 11087758.
Further readingedit
Orlicky DJ (1997). "Negative regulatory activity of a prostaglandin F2 alpha receptor associated protein (FPRP)". Prostaglandins Leukot. Essent. Fatty Acids. 54 (4): 247–59. doi:10.1016/S0952-3278(96)90055-1. PMID 8804121.
Orlicky DJ, Lieber JG, Morin CL, Evans RM (1998). "Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells". J. Lipid Res. 39 (6): 1152–61. doi:10.1016/S0022-2275(20)32539-6. PMID 9643346.
Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
Stipp CS, Orlicky D, Hemler ME (2001). "FPRP, a major, highly stoichiometric, highly specific CD81- and CD9-associated protein". J. Biol. Chem. 276 (7): 4853–62. doi:10.1074/jbc.M009859200. PMID 11087758.
Charrin S, Le Naour F, Oualid M, et al. (2001). "The major CD9 and CD81 molecular partner. Identification and characterization of the complexes". J. Biol. Chem. 276 (17): 14329–37. doi:10.1074/jbc.M011297200. PMID 11278880.
Clark KL, Zeng Z, Langford AL, et al. (2001). "PGRL is a major CD81-associated protein on lymphocytes and distinguishes a new family of cell surface proteins". J. Immunol. 167 (9): 5115–21. doi:10.4049/jimmunol.167.9.5115. PMID 11673522.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Yang XH, Kovalenko OV, Kolesnikova TV, et al. (2006). "Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization". J. Biol. Chem. 281 (18): 12976–85. doi:10.1074/jbc.M510617200. PMID 16537545.
Sala-Valdés M, Ursa A, Charrin S, et al. (2006). "EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins". J. Biol. Chem. 281 (28): 19665–75. doi:10.1074/jbc.M602116200. PMID 16690612.
ptgfrn, prostaglandin, receptor, negative, regulator, protein, that, humans, encoded, gene, also, been, designated, cd315, cluster, differentiation, identifiersaliases, cd315, cd9p, fprp, smap, prostaglandin, receptor, inhibitorexternal, idsomim, 601204, 12771. Prostaglandin F2 receptor negative regulator is a protein that in humans is encoded by the PTGFRN gene 5 6 PTGFRN has also been designated as CD315 cluster of differentiation 315 PTGFRNIdentifiersAliasesPTGFRN CD315 CD9P 1 EWI F FPRP SMAP 6 prostaglandin F2 receptor inhibitorExternal IDsOMIM 601204 MGI 1277114 HomoloGene 7908 GeneCards PTGFRN OMA PTGFRN orthologsGene location Human Chr Chromosome 1 human 1 Band1p13 1Start116 909 916 bp 1 End116 990 353 bp 1 Gene location Mouse Chr Chromosome 3 mouse 2 Band3 3 F2 2Start100 947 548 bp 2 End101 017 594 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inleft uterine tubemyometriumright ventriclesaphenous veinsmooth muscle tissueganglionic eminencepericardiumurethrasecondary oocytegerminal epitheliumTop expressed inbelly cordatriumleft lung loberight lung lobeatrioventricular valvemolarurinary bladderendocardial cushionleft colonepithelium of stomachMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionprotein bindingCellular componentcell surface Golgi apparatus endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane integral component of membraneBiological processlipid droplet organization myoblast fusion involved in skeletal muscle regenerationSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez573819221EnsemblENSG00000134247ENSMUSG00000027864UniProtQ9P2B2Q9WV91RefSeq mRNA NM 020440NM 011197RefSeq protein NP 065173NP 035327Location UCSC Chr 1 116 91 116 99 MbChr 3 100 95 101 02 MbPubMed search 3 4 WikidataView Edit HumanView Edit Mouse Contents 1 Interactions 2 References 3 Further reading 4 External linksInteractions editPTGFRN has been shown to interact with CD9 7 8 and CD81 7 8 References edit a b c GRCh38 Ensembl release 89 ENSG00000134247 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000027864 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Orlicky DJ Berry R Sikela JM Jul 1996 Human chromosome 1 localization of the gene for a prostaglandin F2alpha receptor negative regulatory protein Hum Genet 97 5 655 8 doi 10 1007 BF02281878 PMID 8655148 S2CID 21645802 Entrez Gene PTGFRN prostaglandin F2 receptor negative regulator a b Charrin S Le Naour F Oualid M Billard M Faure G Hanash S M Boucheix C Rubinstein E Apr 2001 The major CD9 and CD81 molecular partner Identification and characterization of the complexes J Biol Chem 276 17 United States 14329 37 doi 10 1074 jbc M011297200 ISSN 0021 9258 PMID 11278880 a b Stipp C S Orlicky D Hemler M E Feb 2001 FPRP a major highly stoichiometric highly specific CD81 and CD9 associated protein J Biol Chem 276 7 United States 4853 62 doi 10 1074 jbc M009859200 ISSN 0021 9258 PMID 11087758 Further reading editOrlicky DJ 1997 Negative regulatory activity of a prostaglandin F2 alpha receptor associated protein FPRP Prostaglandins Leukot Essent Fatty Acids 54 4 247 59 doi 10 1016 S0952 3278 96 90055 1 PMID 8804121 Orlicky DJ Lieber JG Morin CL Evans RM 1998 Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3 L1 cells J Lipid Res 39 6 1152 61 doi 10 1016 S0022 2275 20 32539 6 PMID 9643346 Nagase T Kikuno R Ishikawa KI et al 2000 Prediction of the coding sequences of unidentified human genes XVI The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro DNA Res 7 1 65 73 doi 10 1093 dnares 7 1 65 PMID 10718198 Stipp CS Orlicky D Hemler ME 2001 FPRP a major highly stoichiometric highly specific CD81 and CD9 associated protein J Biol Chem 276 7 4853 62 doi 10 1074 jbc M009859200 PMID 11087758 Charrin S Le Naour F Oualid M et al 2001 The major CD9 and CD81 molecular partner Identification and characterization of the complexes J Biol Chem 276 17 14329 37 doi 10 1074 jbc M011297200 PMID 11278880 Clark KL Zeng Z Langford AL et al 2001 PGRL is a major CD81 associated protein on lymphocytes and distinguishes a new family of cell surface proteins J Immunol 167 9 5115 21 doi 10 4049 jimmunol 167 9 5115 PMID 11673522 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Otsuki T Ota T Nishikawa T et al 2007 Signal sequence and keyword trap in silico for selection of full length human cDNAs encoding secretion or membrane proteins from oligo capped cDNA libraries DNA Res 12 2 117 26 doi 10 1093 dnares 12 2 117 PMID 16303743 Yang XH Kovalenko OV Kolesnikova TV et al 2006 Contrasting effects of EWI proteins integrins and protein palmitoylation on cell surface CD9 organization J Biol Chem 281 18 12976 85 doi 10 1074 jbc M510617200 PMID 16537545 Sala Valdes M Ursa A Charrin S et al 2006 EWI 2 and EWI F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin radixin moesin proteins J Biol Chem 281 28 19665 75 doi 10 1074 jbc M602116200 PMID 16690612 External links editPTGFRN protein human at the U S National Library of Medicine Medical Subject Headings MeSH nbsp This membrane protein related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title PTGFRN amp oldid 1142683661, wikipedia, wiki, book, books, library,
