Nitromersol (metaphen) is a mercury-containing organic compound that is primarily used as an antiseptic and disinfectant. It is a brown-yellow solid that has no odor or taste, does not irritate the skin or mucous membranes, and has no impact on rubber or metallic instruments, including surgical and dental tools.[1]
This compound is a confirmed animal carcinogen. It can emit toxic fumes of NOx and mercury vapor when heated.[2] In 1998, use of nitromersol (and other mercury-containing products) as OTC first-aid antiseptics and products for diaper rash and vaginal contraceptives was disallowed by the FDA.[3] Nitromersol can cause hypersensitivity reactions.[4]
It is still in use as a preservative for vaccines and antitoxins.[examples needed]
See also
Thiomersal – Organomercury antiseptic and antifungal agent
Phenylmercuric nitrate - an organomercury compound with powerful antiseptic and antifungal effects
References
^Hospital formulary and compendium of useful information. Berkeley, California: University of California Press. 1941. p. 113. Retrieved 2011-04-08.
^Lewis, Richard J. (2008). Hazardous chemicals desk reference. Wiley-Interscience. p. 1018. ISBN978-0-470-18024-2. Retrieved 2011-04-08.
^Remington: the science and practice of pharmacy. Medicine Series. Vol. 1 (21st ed.). Lippincott Williams & Wilkins. 2005. p. 369. ISBN0-7817-4673-6.
^Trevor, Anthony J.; Katzung, Bertram G.; Masters, Susan B. (2007). Katzung & Trevor's pharmacology: examination & board review. Lange Basic Science (8th ed.). McGraw-Hill Professional. p. 420. ISBN978-0-07-148869-3.
January 26, 2023
nitromersol, metaphen, mercury, containing, organic, compound, that, primarily, used, antiseptic, disinfectant, brown, yellow, solid, that, odor, taste, does, irritate, skin, mucous, membranes, impact, rubber, metallic, instruments, including, surgical, dental. Nitromersol metaphen is a mercury containing organic compound that is primarily used as an antiseptic and disinfectant It is a brown yellow solid that has no odor or taste does not irritate the skin or mucous membranes and has no impact on rubber or metallic instruments including surgical and dental tools 1 Nitromersol NamesIUPAC name 5 Methyl 2 nitro 7 oxa 8 mercurabicyclo 4 2 0 octa 1 6 2 4 trieneOther names Metaphen 6 Methyl 3 nitrobenzoxamercurete 4 Nitro 5 hydroxymercuriorthocresolIdentifiersCAS Number 133 58 4 Y3D model JSmol Interactive imageChemSpider 16739372ECHA InfoCard 100 004 648PubChem CID 16682935UNII RU6242GP15CompTox Dashboard EPA DTXSID9057638InChI InChI 1S C7H6NO3 Hg c1 5 2 3 6 8 10 11 4 7 5 9 h2 3 9H 1H3 q 1 p 1Key UEHLXXJAWYWUGI UHFFFAOYSA MInChI 1 C7H6NO3 Hg c1 5 2 3 6 8 10 11 4 7 5 9 h2 3 9H 1H3 q 1 p 1 rC7H5HgNO3 c1 4 2 3 5 9 10 11 6 7 4 12 8 6 h2 3H 1H3Key UEHLXXJAWYWUGI ITKDQSLKATSMILES Cc1ccc c2 Hg Oc12 N O OPropertiesChemical formula C 7H 5Hg N O 3Molar mass 351 713 g mol 1HazardsOccupational safety and health OHS OSH Main hazards moderately toxicExcept where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Infobox references This compound is a confirmed animal carcinogen It can emit toxic fumes of NOx and mercury vapor when heated 2 In 1998 use of nitromersol and other mercury containing products as OTC first aid antiseptics and products for diaper rash and vaginal contraceptives was disallowed by the FDA 3 Nitromersol can cause hypersensitivity reactions 4 It is still in use as a preservative for vaccines and antitoxins examples needed See also EditThiomersal Organomercury antiseptic and antifungal agent Phenylmercuric nitrate an organomercury compound with powerful antiseptic and antifungal effectsReferences Edit Hospital formulary and compendium of useful information Berkeley California University of California Press 1941 p 113 Retrieved 2011 04 08 Lewis Richard J 2008 Hazardous chemicals desk reference Wiley Interscience p 1018 ISBN 978 0 470 18024 2 Retrieved 2011 04 08 Remington the science and practice of pharmacy Medicine Series Vol 1 21st ed Lippincott Williams amp Wilkins 2005 p 369 ISBN 0 7817 4673 6 Trevor Anthony J Katzung Bertram G Masters Susan B 2007 Katzung amp Trevor s pharmacology examination amp board review Lange Basic Science 8th ed McGraw Hill Professional p 420 ISBN 978 0 07 148869 3 Retrieved from https en wikipedia org w index php title Nitromersol amp oldid 1046726632, wikipedia, wiki, book, books, library,
