N1-Methyl-4-pyridone-3-carboxamide, also abbreviated as 4PY, is a breakdown product of niacin,[1] that is associated with an increased risk of cardiovascular disease.[2] It has 2 carbonyl groups that are close to each other.[3][4][5]
^Cosmetic Ingredient Review Expert Panel (2005). "Final report of the safety assessment of niacinamide and niacin". International Journal of Toxicology. 24 (Suppl 5): 1–31. doi:10.1080/10915810500434183. PMID 16596767. S2CID 208149068.
^Ferrell M, Wang Z, Anderson JT, Li XS, Witkowski M, DiDonato JA, Hilser JR, Hartiala JA, Haghikia A, Cajka T, Fiehn O, Sangwan N, Demuth I, König M, Steinhagen-Thiessen E, Landmesser U, Tang WH, Allayee H, Hazen SL (February 2024). "A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk". Nature Medicine. 30 (2): 424–434. doi:10.1038/s41591-023-02793-8. PMID 38374343.
^"Cleveland Clinic-Led Study Discovers Link between High Levels of Niacin – a Common B Vitamin – and Heart Disease". 19 February 2024.
^"N1-Methyl-4-pyridone-3-carboxamide". Toxin and Toxin Target Database (T3DB). T3D4179.
^MasterJohn C (24 February 2024). "NMN Probably Won't Make You Live Forever". Substack.
methyl, pyridone, carboxamide, also, abbreviated, breakdown, product, niacin, that, associated, with, increased, risk, cardiovascular, disease, carbonyl, groups, that, close, each, other, names, iupac, name, methyl, oxopyridine, carboxamide, other, names, iden. N1 Methyl 4 pyridone 3 carboxamide also abbreviated as 4PY is a breakdown product of niacin 1 that is associated with an increased risk of cardiovascular disease 2 It has 2 carbonyl groups that are close to each other 3 4 5 N1 Methyl 4 pyridone 3 carboxamide Names IUPAC name 1 Methyl 4 oxopyridine 3 carboxamide Other names 4PY Identifiers CAS Number 769 49 3 3D model JSmol Interactive image PubChem CID 440810 CompTox Dashboard EPA DTXSID80227697 SMILES CN1C CC O C C1 C O N Properties Chemical formula C 7H 8N 2O 2 Molar mass 152 153 g mol 1 Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Infobox referencesReferences edit Cosmetic Ingredient Review Expert Panel 2005 Final report of the safety assessment of niacinamide and niacin International Journal of Toxicology 24 Suppl 5 1 31 doi 10 1080 10915810500434183 PMID 16596767 S2CID 208149068 Ferrell M Wang Z Anderson JT Li XS Witkowski M DiDonato JA Hilser JR Hartiala JA Haghikia A Cajka T Fiehn O Sangwan N Demuth I Konig M Steinhagen Thiessen E Landmesser U Tang WH Allayee H Hazen SL February 2024 A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk Nature Medicine 30 2 424 434 doi 10 1038 s41591 023 02793 8 PMID 38374343 Cleveland Clinic Led Study Discovers Link between High Levels of Niacin a Common B Vitamin and Heart Disease 19 February 2024 N1 Methyl 4 pyridone 3 carboxamide Toxin and Toxin Target Database T3DB T3D4179 MasterJohn C 24 February 2024 NMN Probably Won t Make You Live Forever Substack nbsp This molecular biology article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title N1 Methyl 4 pyridone 3 carboxamide amp oldid 1211169137, wikipedia, wiki, book, books, library,
