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Methyldiazinol

Methyldiazinol (also known as 3,3-azo-17α-methyl-5α-dihydrotestosterone, 3-azi-17α-methyl-DHT, or 3,3-azo-17α-methyl-5α-androstan-17β-ol) is a synthetic and orally active androgen/anabolic steroid (AAS) which was never marketed.[1][2] It is a 17α-methylated derivative of dihydrotestosterone (DHT); specifically, it is the C3 azi (i.e., 3,3-azo) analogue of mestanolone (17α-methyl-DHT).[1][2] The drug has been found to possess a high ratio and dissociation of myotrophic to androgenic activity; relative to methyltestosterone, its ratio was 15 (3:0.2), among the highest observed.[1][2]

Methyldiazinol
Clinical data
Other namesMethyldiazirinol; 3,3-Azo-17α-methyl-5α-dihydrotestosterone; 3,3-Azo-17α-methyl-DHT; 3,3-Azo-17α-methyl-5α-androstan-17β-ol; 3-Azi-17α-methyl-5α-androstan-17β-ol
Routes of
administration
By mouth
Drug classAndrogen; Anabolic steroid
Identifiers
  • (5S,8R,9S,10S,13S,14S,17S)-10,13,17-Trimethylspiro[2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,3'-diazirine]-17-ol
CAS Number
  • 2429-17-6
PubChem CID
  • 112500385
ChemSpider
  • 52084890
UNII
  • 7AA03AP597
Chemical and physical data
FormulaC20H32N2O
Molar mass316.489 g·mol−1
3D model (JSmol)
  • Interactive image
  • C[C@]12CCC3(C[C@@H]1CC[C@@H]4[C@@H]2CC[C@]5([C@H]4CC[C@]5(C)O)C)N=N3
  • InChI=LMNFACKYKJIJHJ-PHFHYRSDSA-N
  • Key:1S/C20H32N2O/c1-17-10-11-20(21-22-20)12-13(17)4-5-14-15(17)6-8-18(2)16(14)7-9-19(18,3)23/h13-16,23H,4-12H2,1-3H3/t13-,14+,15-,16-,17-,18-,19-/m0/s1

See also

References

  1. ^ a b c Kochakian CD (6 December 2012). Anabolic-Androgenic Steroids. Springer Science & Business Media. p. 385. ISBN 978-3-642-66353-6. Methyldiazinol: 3-Azi-17-methyl-5α-androstan-17β-ol: The 3-azi derivative of methandrostanolone was noted by CHURCH et al. (1965) to have a wide myotrophic:androgenic dissociation (3: 0.2) 15 relative to methyltestosterone orally, among the highest noted.
  2. ^ a b c Church RF, Kende AS, Weiss MJ (1965). "Diazirines. I. Some Observations on the Scope of the Ammonia-Hydroxylamine-O-sulfonic Acid Diaziridine Synthesis. The Preparation of Certain Steroid Diaziridines and Diazirines". Journal of the American Chemical Society. 87 (12): 2665–2671. doi:10.1021/ja01090a025. ISSN 0002-7863.

methyldiazinol, also, known, 17α, methyl, dihydrotestosterone, 17α, methyl, 17α, methyl, androstan, 17β, synthetic, orally, active, androgen, anabolic, steroid, which, never, marketed, 17α, methylated, derivative, dihydrotestosterone, specifically, analogue, m. Methyldiazinol also known as 3 3 azo 17a methyl 5a dihydrotestosterone 3 azi 17a methyl DHT or 3 3 azo 17a methyl 5a androstan 17b ol is a synthetic and orally active androgen anabolic steroid AAS which was never marketed 1 2 It is a 17a methylated derivative of dihydrotestosterone DHT specifically it is the C3 azi i e 3 3 azo analogue of mestanolone 17a methyl DHT 1 2 The drug has been found to possess a high ratio and dissociation of myotrophic to androgenic activity relative to methyltestosterone its ratio was 15 3 0 2 among the highest observed 1 2 MethyldiazinolClinical dataOther namesMethyldiazirinol 3 3 Azo 17a methyl 5a dihydrotestosterone 3 3 Azo 17a methyl DHT 3 3 Azo 17a methyl 5a androstan 17b ol 3 Azi 17a methyl 5a androstan 17b olRoutes ofadministrationBy mouthDrug classAndrogen Anabolic steroidIdentifiersIUPAC name 5S 8R 9S 10S 13S 14S 17S 10 13 17 Trimethylspiro 2 4 5 6 7 8 9 11 12 14 15 16 dodecahydro 1H cyclopenta a phenanthrene 3 3 diazirine 17 olCAS Number2429 17 6PubChem CID112500385ChemSpider52084890UNII7AA03AP597Chemical and physical dataFormulaC 20H 32N 2OMolar mass316 489 g mol 13D model JSmol Interactive imageSMILES C C 12CCC3 C C H 1CC C H 4 C H 2CC C 5 C H 4CC C 5 C O C N N3InChI InChI LMNFACKYKJIJHJ PHFHYRSDSA NKey 1S C20H32N2O c1 17 10 11 20 21 22 20 12 13 17 4 5 14 15 17 6 8 18 2 16 14 7 9 19 18 3 23 h13 16 23H 4 12H2 1 3H3 t13 14 15 16 17 18 19 m0 s1See also EditList of androgens anabolic steroidsReferences Edit a b c Kochakian CD 6 December 2012 Anabolic Androgenic Steroids Springer Science amp Business Media p 385 ISBN 978 3 642 66353 6 Methyldiazinol 3 Azi 17 methyl 5a androstan 17b ol The 3 azi derivative of methandrostanolone was noted by CHURCH et al 1965 to have a wide myotrophic androgenic dissociation 3 0 2 15 relative to methyltestosterone orally among the highest noted a b c Church RF Kende AS Weiss MJ 1965 Diazirines I Some Observations on the Scope of the Ammonia Hydroxylamine O sulfonic Acid Diaziridine Synthesis The Preparation of Certain Steroid Diaziridines and Diazirines Journal of the American Chemical Society 87 12 2665 2671 doi 10 1021 ja01090a025 ISSN 0002 7863 This drug article relating to the genito urinary system is a stub You can help Wikipedia by expanding it vte This article about a steroid is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Methyldiazinol amp oldid 1084547812, wikipedia, wiki, book, books, library,

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